The Experts below are selected from a list of 189 Experts worldwide ranked by ideXlab platform
Maria Chiaramonte - One of the best experts on this subject based on the ideXlab platform.
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Hepatocellular carcinoma in primary Biliary Cirrhosis
Journal of hepatology, 1994Co-Authors: Fabio Farinati, Annarosa Floreani, N. De Maria, Stefano Fagiuoli, Remo Naccarato, Maria ChiaramonteAbstract:Primary Biliary Cirrhosis is considered a low risk for the development of hepatocellular carcinoma. We evaluated the incidence of hepatocellular carcinoma in a cohort of 89 female primary Biliary Cirrhosis patients and, as a control group, in 73 female patients with Cirrhosis of a different etiology. The patients underwent ultrasound and alfa-fetoprotein determination every 6 months. Two patients developed hepatocellular carcinoma in the primary Biliary Cirrhosis and three in the control group, respectively. The Relative Risk for hepatocellular carcinoma in primary Biliary Cirrhosis patients was 0.7. However, when considering only stage IV, primary Biliary Cirrhosis patients with Cirrhosis, the Relative Risk was actually 1.5 with respect to controls, with 1.4% cases of hepatocellular carcinoma per year. These data suggest that the risk of hepatocellular carcinoma is similar in female patients with primary Biliary Cirrhosis and in female patients with Cirrhosis of a different etiology.
Yulan Liu - One of the best experts on this subject based on the ideXlab platform.
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Primary Biliary Cirrhosis and ulcerative colitis: A case report and review of literature
World journal of gastroenterology, 2003Co-Authors: Wenbin Xiao, Yulan LiuAbstract:AIM: To summarize the characteristics of patients suffered from primary Biliary Cirrhosis associated with ulcerative colitis. METHODS: To report a new case and review the literature. RESULTS: There were 18 cases (including our case) of primary Biliary Cirrhosis complicated with ulcerative colitis reported in the literature. Compared with classical primary Biliary Cirrhosis, the patients were more often males and younger similar. The bowel lesions were usually mild with proctitis predominated. While ulcerative colitis was diagnosed before primary Biliary Cirrhosis in 13 cases, the presentation of primary Biliary Cirrhosis was earlier than that of ulcerative colitis in our new case reported here. The prevalence of primary Biliary Cirrhosis among patients of ulcerative colitis was almost 30 times higher than in general population. CONCLUSION: Association of primary Biliary Cirrhosis with ulcerative colitis is rare. It should be considered in the differential diagnosis of hepatoBiliary disease in patients with ulcerative colitis, and vice versa.
Elias A. Kouroumalis - One of the best experts on this subject based on the ideXlab platform.
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Ulcerative colitis associated with primary Biliary Cirrhosis.
Digestive diseases and sciences, 1999Co-Authors: M. Koulentaki, Ioannis E. Koutroubakis, Efthimia Petinaki, Maria Tzardi, H. Oekonomaki, I. A. Mouzas, Elias A. KouroumalisAbstract:Primary Biliary Cirrhosis and ulcerative colitis are two diseases with many features of autoimmunity. Thirteen cases of coexistence of the two diseases have been reported in the literature so far. Patients are usually younger and more often males than the ordinary primary Biliary Cirrhosis patient, while the colitis is mild and easily controllable. In a homogeneous population of 550,000 inhabitants of the island of Crete, 412 cases of ulcerative colitis and 82 individuals with primary Biliary Cirrhosis or autoimmune cholangitis have been identified. In two cases, coexistence of the two diseases was found. Immunological screening for AMA positivity in 150 ulcerative colitis sera disclosed no further cases. Prevalence of primary Biliary Cirrhosis in ulcerative colitis patients seems at least 30 times higher than in the general population in our area. A possible immunological link between the two diseases is discussed.
Dipalma Ja - One of the best experts on this subject based on the ideXlab platform.
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Recognizing primary Biliary Cirrhosis and primary sclerosing cholangitis.
American Family Physician, 1996Co-Authors: Buckley Se, Dipalma JaAbstract:Nonsuppurative cholangiopathies such as primary Biliary Cirrhosis and primary sclerosing cholangitis are chronic cholestatic liver diseases that result from inflammation of the Biliary system. Recent advances in management options for patients with primary Biliary Cirrhosis and primary sclerosing cholangitis have facilitated treatment by family physicians. Patients with significant laboratory abnormalities on liver tests for cholestasis should be evaluated for possible primary Biliary Cirrhosis or primary sclerosing cholangitis. Investigation with liver biopsy and endoscopic retrograde cholangiopancreatography should be considered if abnormal biochemical findings remain unexplained after a careful history and physical examination are performed, a thorough medication history is obtained and abdominal ultrasonography is conducted to search for Biliary obstruction.
Fabio Farinati - One of the best experts on this subject based on the ideXlab platform.
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Hepatocellular carcinoma in primary Biliary Cirrhosis
Journal of hepatology, 1994Co-Authors: Fabio Farinati, Annarosa Floreani, N. De Maria, Stefano Fagiuoli, Remo Naccarato, Maria ChiaramonteAbstract:Primary Biliary Cirrhosis is considered a low risk for the development of hepatocellular carcinoma. We evaluated the incidence of hepatocellular carcinoma in a cohort of 89 female primary Biliary Cirrhosis patients and, as a control group, in 73 female patients with Cirrhosis of a different etiology. The patients underwent ultrasound and alfa-fetoprotein determination every 6 months. Two patients developed hepatocellular carcinoma in the primary Biliary Cirrhosis and three in the control group, respectively. The Relative Risk for hepatocellular carcinoma in primary Biliary Cirrhosis patients was 0.7. However, when considering only stage IV, primary Biliary Cirrhosis patients with Cirrhosis, the Relative Risk was actually 1.5 with respect to controls, with 1.4% cases of hepatocellular carcinoma per year. These data suggest that the risk of hepatocellular carcinoma is similar in female patients with primary Biliary Cirrhosis and in female patients with Cirrhosis of a different etiology.