The Experts below are selected from a list of 54132 Experts worldwide ranked by ideXlab platform
Ron Milo - One of the best experts on this subject based on the ideXlab platform.
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equilibrator the Biochemical thermodynamics calculator
Nucleic Acids Research, 2012Co-Authors: Avi I Flamholz, Elad Noor, Arren Bareven, Ron MiloAbstract:The laws of thermodynamics constrain the action of Biochemical systems. However, thermodynamic data on Biochemical Compounds can be difficult to find and is cumbersome to perform calculations with manually. Even simple thermodynamic questions like ‘how much Gibbs energy is released by ATP hydrolysis at pH 5?’ are complicated excessively by the search for accurate data. To address this problem, eQuilibrator couples a comprehensive and accurate database of thermodynamic properties of Biochemical Compounds and reactions with a simple and powerful online search and calculation interface. The web interface to eQuilibrator (http://equilibrator.weizmann.ac.il) enables easy calculation of Gibbs energies of Compounds and reactions given arbitrary pH, ionic strength and metabolite concentrations. The eQuilibrator code is open-source and all thermodynamic source data are freely downloadable in standard formats. Here we describe the database characteristics and implementation and demonstrate its use.
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eQuilibrator—the Biochemical thermodynamics calculator
Nucleic Acids Research, 2011Co-Authors: Avi I Flamholz, Elad Noor, Arren Bar-even, Ron MiloAbstract:The laws of thermodynamics constrain the action of Biochemical systems. However, thermodynamic data on Biochemical Compounds can be difficult to find and is cumbersome to perform calculations with manually. Even simple thermodynamic questions like ‘how much Gibbs energy is released by ATP hydrolysis at pH 5?’ are complicated excessively by the search for accurate data. To address this problem, eQuilibrator couples a comprehensive and accurate database of thermodynamic properties of Biochemical Compounds and reactions with a simple and powerful online search and calculation interface. The web interface to eQuilibrator (http://equilibrator.weizmann.ac.il) enables easy calculation of Gibbs energies of Compounds and reactions given arbitrary pH, ionic strength and metabolite concentrations. The eQuilibrator code is open-source and all thermodynamic source data are freely downloadable in standard formats. Here we describe the database characteristics and implementation and demonstrate its use.
Avi I Flamholz - One of the best experts on this subject based on the ideXlab platform.
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equilibrator the Biochemical thermodynamics calculator
Nucleic Acids Research, 2012Co-Authors: Avi I Flamholz, Elad Noor, Arren Bareven, Ron MiloAbstract:The laws of thermodynamics constrain the action of Biochemical systems. However, thermodynamic data on Biochemical Compounds can be difficult to find and is cumbersome to perform calculations with manually. Even simple thermodynamic questions like ‘how much Gibbs energy is released by ATP hydrolysis at pH 5?’ are complicated excessively by the search for accurate data. To address this problem, eQuilibrator couples a comprehensive and accurate database of thermodynamic properties of Biochemical Compounds and reactions with a simple and powerful online search and calculation interface. The web interface to eQuilibrator (http://equilibrator.weizmann.ac.il) enables easy calculation of Gibbs energies of Compounds and reactions given arbitrary pH, ionic strength and metabolite concentrations. The eQuilibrator code is open-source and all thermodynamic source data are freely downloadable in standard formats. Here we describe the database characteristics and implementation and demonstrate its use.
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eQuilibrator—the Biochemical thermodynamics calculator
Nucleic Acids Research, 2011Co-Authors: Avi I Flamholz, Elad Noor, Arren Bar-even, Ron MiloAbstract:The laws of thermodynamics constrain the action of Biochemical systems. However, thermodynamic data on Biochemical Compounds can be difficult to find and is cumbersome to perform calculations with manually. Even simple thermodynamic questions like ‘how much Gibbs energy is released by ATP hydrolysis at pH 5?’ are complicated excessively by the search for accurate data. To address this problem, eQuilibrator couples a comprehensive and accurate database of thermodynamic properties of Biochemical Compounds and reactions with a simple and powerful online search and calculation interface. The web interface to eQuilibrator (http://equilibrator.weizmann.ac.il) enables easy calculation of Gibbs energies of Compounds and reactions given arbitrary pH, ionic strength and metabolite concentrations. The eQuilibrator code is open-source and all thermodynamic source data are freely downloadable in standard formats. Here we describe the database characteristics and implementation and demonstrate its use.
Michael L. Mavrovouniotis - One of the best experts on this subject based on the ideXlab platform.
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Estimation of standard Gibbs energy changes of biotransformations.
The Journal of biological chemistry, 1991Co-Authors: Michael L. MavrovouniotisAbstract:Contributions and corrections for the estimation of standard Gibbs energies are given. The group contribution method, applicable to both cyclic and acyclic Compounds, permits the approximate estimation of the standard Gibbs energy of a biotransformation, given the stoichiometry and structures of the metabolites involved. Estimated standard Gibbs energies of formation for a number of acyclic Biochemical Compounds are provided.
Elad Noor - One of the best experts on this subject based on the ideXlab platform.
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equilibrator the Biochemical thermodynamics calculator
Nucleic Acids Research, 2012Co-Authors: Avi I Flamholz, Elad Noor, Arren Bareven, Ron MiloAbstract:The laws of thermodynamics constrain the action of Biochemical systems. However, thermodynamic data on Biochemical Compounds can be difficult to find and is cumbersome to perform calculations with manually. Even simple thermodynamic questions like ‘how much Gibbs energy is released by ATP hydrolysis at pH 5?’ are complicated excessively by the search for accurate data. To address this problem, eQuilibrator couples a comprehensive and accurate database of thermodynamic properties of Biochemical Compounds and reactions with a simple and powerful online search and calculation interface. The web interface to eQuilibrator (http://equilibrator.weizmann.ac.il) enables easy calculation of Gibbs energies of Compounds and reactions given arbitrary pH, ionic strength and metabolite concentrations. The eQuilibrator code is open-source and all thermodynamic source data are freely downloadable in standard formats. Here we describe the database characteristics and implementation and demonstrate its use.
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eQuilibrator—the Biochemical thermodynamics calculator
Nucleic Acids Research, 2011Co-Authors: Avi I Flamholz, Elad Noor, Arren Bar-even, Ron MiloAbstract:The laws of thermodynamics constrain the action of Biochemical systems. However, thermodynamic data on Biochemical Compounds can be difficult to find and is cumbersome to perform calculations with manually. Even simple thermodynamic questions like ‘how much Gibbs energy is released by ATP hydrolysis at pH 5?’ are complicated excessively by the search for accurate data. To address this problem, eQuilibrator couples a comprehensive and accurate database of thermodynamic properties of Biochemical Compounds and reactions with a simple and powerful online search and calculation interface. The web interface to eQuilibrator (http://equilibrator.weizmann.ac.il) enables easy calculation of Gibbs energies of Compounds and reactions given arbitrary pH, ionic strength and metabolite concentrations. The eQuilibrator code is open-source and all thermodynamic source data are freely downloadable in standard formats. Here we describe the database characteristics and implementation and demonstrate its use.
Arren Bar-even - One of the best experts on this subject based on the ideXlab platform.
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eQuilibrator—the Biochemical thermodynamics calculator
Nucleic Acids Research, 2011Co-Authors: Avi I Flamholz, Elad Noor, Arren Bar-even, Ron MiloAbstract:The laws of thermodynamics constrain the action of Biochemical systems. However, thermodynamic data on Biochemical Compounds can be difficult to find and is cumbersome to perform calculations with manually. Even simple thermodynamic questions like ‘how much Gibbs energy is released by ATP hydrolysis at pH 5?’ are complicated excessively by the search for accurate data. To address this problem, eQuilibrator couples a comprehensive and accurate database of thermodynamic properties of Biochemical Compounds and reactions with a simple and powerful online search and calculation interface. The web interface to eQuilibrator (http://equilibrator.weizmann.ac.il) enables easy calculation of Gibbs energies of Compounds and reactions given arbitrary pH, ionic strength and metabolite concentrations. The eQuilibrator code is open-source and all thermodynamic source data are freely downloadable in standard formats. Here we describe the database characteristics and implementation and demonstrate its use.