The Experts below are selected from a list of 4170 Experts worldwide ranked by ideXlab platform
Changming Dong - One of the best experts on this subject based on the ideXlab platform.
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synthesis and ph sensitive self assembly of dendritic poly amidoamine b poly l glutamate Biohybrids
Chinese Journal of Polymer Science, 2009Co-Authors: Shuo Qiu, Hui Huang, Changming DongAbstract:Dendritic poly(amidoamine)-b-poly(L-glutamate) (PAMAM-b-PLG) Biohybrids were synthesized by the ring-opening polymerization of γ-benzyl-L-glutamate N-carboxyanhydride monomer, followed by the deprotection of benzyl groups on poly(benzyl-L-glutamate), and were characterized by 1H-NMR, FT-IR and gel permeation chromatography. The self-assembly behavior of the PAMAM-b-PLG biohybrid was investigated by means of UV-Vis, dynamic light scattering (DLS), transmission electronic microscopy (TEM) and 1H-NMR. UV-Vis analysis demonstrated that the critical aggregation concentration of PAMAM-b-PLG was dependent on the pH value of aqueous solutios. DLS results further evidenced that the PAMAM-b-PLG biohybrid exhibited a pH-sensitive self-assembly behavior, and the average size of the self-assembled nanoparticles decreased gradually with the increasing pH value of the PAMAM-b-PLG solution. The self-assembled nanoparticles gave a nearly spherical morphology, and the pH-induced self-assembly had no obvious effect on the morphology of nanoparticles.
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star shaped polypeptide glycopolymer Biohybrids synthesis self assembly biomolecular recognition and controlled drug release behavior
Journal of Polymer Science Part A, 2009Co-Authors: Shuo Qiu, Hui Huang, Wei Zhou, Xiaohui Dai, Changming DongAbstract:Star-shaped polypeptide/glycopolymer Biohybrids composed of poly(γ- benzyl L-glutamate) and poly(D-gluconamidoethyl methacrylate), exhibiting controlled molecular weights and low polydispersities, were synthesized by the combination of ring-opening polymerization of γ-benzyl-L-glutamate N-carboxyanhydride and the direct atom transfer radical polymerization of unprotected D-gluconamidoethyl methacrylate glycomonomer. These Biohybrids were characterized in detail by means of FTIR, 1H NMR, gel permeation chromatography, differential scanning calorimetry, and wide angle X-ray diffraction. Independent of weight fraction of hydrophilic glycopolymer segment, the Biohybrids self-assembled into large spherical micelles in aqueous solution, which had a helical polypeptide core surrounded by a multivalent glycopolymer shell. The deprotected poly(L-glutamate)/glycopolymer hybrid exhibited a pH-sensitive self-assembly behavior, and the average size of the nanoparticles decreased gradually over the aqueous pH value. Moreover, whatever these Biohybrids existed in unimolecular level or glycopolymer-surfaced nanoparticles, they had specific biomolecular recognition with Concanavalin A compared with bovine serum albumin. Furthermore, star-shaped Biohybrids showed a higher doxorubicin loading efficiency and longer drug-release time than linear analogues. This potentially provides a platform for fabricating targeted anticancer drug delivery system and studying glycoprotein functions in vitro. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 47: 2009–2023, 2009
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star shaped polypeptide glycopolymer Biohybrids synthesis self assembly biomolecular recognition and controlled drug release behavior part a polymer chemistry
Journal of Polymer Science, 2009Co-Authors: Shuo Qiu, Hui Huang, Wei Zhou, Xiaohui Dai, Changming DongAbstract:Star-shaped polypeptide/glycopolymer Biohybrids composed of poly(γ- benzyl L-glutamate) and poly(D-gluconamidoethyl methacrylate), exhibiting controlled molecular weights and low polydispersities, were synthesized by the combination of ring-opening polymerization of γ-benzyl-L-glutamate N-carboxyanhydride and the direct atom transfer radical polymerization of unprotected D-gluconamidoethyl methacrylate glycomonomer. These Biohybrids were characterized in detail by means of FTIR, ¹H NMR, gel permeation chromatography, differential scanning calorimetry, and wide angle X-ray diffraction. Independent of weight fraction of hydrophilic glycopolymer segment, the Biohybrids self-assembled into large spherical micelles in aqueous solution, which had a helical polypeptide core surrounded by a multivalent glycopolymer shell. The deprotected poly(L-glutamate)/glycopolymer hybrid exhibited a pH-sensitive self-assembly behavior, and the average size of the nanoparticles decreased gradually over the aqueous pH value. Moreover, whatever these Biohybrids existed in unimolecular level or glycopolymer-surfaced nanoparticles, they had specific biomolecular recognition with Concanavalin A compared with bovine serum albumin. Furthermore, star-shaped Biohybrids showed a higher doxorubicin loading efficiency and longer drug-release time than linear analogues. This potentially provides a platform for fabricating targeted anticancer drug delivery system and studying glycoprotein functions in vitro.
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Biodegradable and Biomimetic Poly(ε‐caprolactone)/Poly(lactobionamidoethyl methacrylate) Biohybrids: Synthesis, Lactose‐Installed Nanoparticles and Recognition Properties
Macromolecular bioscience, 2008Co-Authors: Wei Zhou, Xiaohui Dai, Changming DongAbstract:Biodegradable and biomimetic SPCL-PLAMA Biohybrids were synthesized via ATRP and characterized by FT-IR, 1 H NMR, GPC and DSC. Biohybrids with small PDI were obtained, and the block length of the PLAMA glycopolymer could be varied linearly by the varying the molar ratio of glycomonomer to macroinitiator. The outer PLAMA glycopolymer restrained the crystallization of inner PCL segments. The self-assembly properties of amphiphilic Biohybrids were studied. Lactose-installed aggregates were fabricated in aqueous solution; they changed from spherical micelles to vesicles with increasing weight fraction of hydrophobic PCL. The SPCL-PLAMA Biohybrids showed specific recognition for RCA 120 lectin.
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biodegradable and biomimetic poly e caprolactone poly lactobionamidoethyl methacrylate Biohybrids synthesis lactose installed nanoparticles and recognition properties
Macromolecular Bioscience, 2008Co-Authors: Wei Zhou, Xiaohui Dai, Changming DongAbstract:Biodegradable and biomimetic SPCL-PLAMA Biohybrids were synthesized via ATRP and characterized by FT-IR, 1 H NMR, GPC and DSC. Biohybrids with small PDI were obtained, and the block length of the PLAMA glycopolymer could be varied linearly by the varying the molar ratio of glycomonomer to macroinitiator. The outer PLAMA glycopolymer restrained the crystallization of inner PCL segments. The self-assembly properties of amphiphilic Biohybrids were studied. Lactose-installed aggregates were fabricated in aqueous solution; they changed from spherical micelles to vesicles with increasing weight fraction of hydrophobic PCL. The SPCL-PLAMA Biohybrids showed specific recognition for RCA 120 lectin.
Aji P Mathew - One of the best experts on this subject based on the ideXlab platform.
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cellulose nanofiber graphene oxide Biohybrids disclosing the self assembly and copper ion adsorption using advanced microscopy and reaxff simulations
ACS Nano, 2018Co-Authors: Chuantao Zhu, Susanna Monti, Aji P MathewAbstract:The self-assembly of nanocellulose and graphene oxide into highly porous biohybrid materials has inspired the design and synthesis of multifunctional membranes for removing water pollutants. The mechanisms of self-assembly, metal ion capture, and cluster formation on the Biohybrids at the nano- and molecular scales are quite complex. Their elucidation requires evidence from the synergistic combination of experimental data and computational models. The AFM-based microscopy studies of (2,2,6,6-tetramethylpiperidine-1-oxylradical)-mediated oxidized cellulose nanofibers (TOCNFs), graphene oxide (GO), and their biohybrid membranes provide strong, direct evidence of self-assembly; small GO nanoparticles first attach and accumulate along a single TOCNF fiber, while the long, flexible TOCNF filaments wrap around the flat, wide GO planes, thus forming an amorphous and porous biohybrid network. The layered structure of the TOCNFs and GO membrane, derived from the self-assembly and its surface properties before and ...
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Cellulose Nanofiber–Graphene Oxide Biohybrids: Disclosing the Self-Assembly and Copper-Ion Adsorption Using Advanced Microscopy and ReaxFF Simulations
2018Co-Authors: Chuantao Zhu, Susanna Monti, Aji P MathewAbstract:The self-assembly of nanocellulose and graphene oxide into highly porous biohybrid materials has inspired the design and synthesis of multifunctional membranes for removing water pollutants. The mechanisms of self-assembly, metal ion capture, and cluster formation on the Biohybrids at the nano- and molecular scales are quite complex. Their elucidation requires evidence from the synergistic combination of experimental data and computational models. The AFM-based microscopy studies of (2,2,6,6-tetramethylpiperidine-1-oxylradical)-mediated oxidized cellulose nanofibers (TOCNFs), graphene oxide (GO), and their biohybrid membranes provide strong, direct evidence of self-assembly; small GO nanoparticles first attach and accumulate along a single TOCNF fiber, while the long, flexible TOCNF filaments wrap around the flat, wide GO planes, thus forming an amorphous and porous biohybrid network. The layered structure of the TOCNFs and GO membrane, derived from the self-assembly and its surface properties before and after the adsorption of Cu(II), is investigated by advanced microscopy techniques and is further clarified by the ReaxFF molecular dynamics (MD) simulations. The dynamics of the Cu(II)-ion capture by the TOCNF and GO membranes in solution and the ion cluster formation during drying are confirmed by the MD simulations. The results of this multidisciplinary investigation move the research one step forward by disclosing specific aspects of the self-assembly behavior of biospecies and suggesting effective design strategies to control the pore size and robust materials for industrial applications
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tempo cellulose nanofiber graphene oxide Biohybrids disclosing self assembly and cu ii adsorption using advanced microscopy and reaxff molecular dynamics simulations
2018Co-Authors: Chuantao Zhu, Susanna Monti, Aji P MathewAbstract:TEMPO Cellulose Nanofiber - Graphene Oxide Biohybrids : Disclosing Self-Assembly and Cu(II) Adsorption using Advanced Microscopy and ReaxFF Molecular Dynamics Simulations
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Self-Assembled TEMPO Cellulose Nanofibers: Graphene Oxide-Based Biohybrids for Water Purification
ACS applied materials & interfaces, 2017Co-Authors: Chuantao Zhu, Peng Liu, Aji P MathewAbstract:Nanocellulose, graphene oxide (GO), and their combinations there off have attracted great attention for the application of water purification recently because of their unique adsorption capacity, mechanical characteristics, coordination with transition metal ions, surface charge density, and so on. In the current study, (2,2,6,6-tetramethylpiperidine-1-oxylradical) (TEMPO)-mediated oxidized cellulose nanofibers (TOCNF) and GO sheets or graphene oxide nanocolloid (nanoGO) Biohybrids were prepared by vacuum filtration method to obtain self-assembled adsorbents and membranes for water purification. The porous biohybrid structure, studied using advanced microscopy techniques, revealed a unique networking and self-assembling of TOCNF, GO, and nanoGO, driven by the morphology of the GO phase and stabilized by the intermolecular H-bonding between carboxyl groups and hydroxyl groups. The Biohybrids exhibited a promising adsorption capacity toward Cu(II) due to TOCNF and formed a unique “arrested state” in water b...
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Self-Assembled TEMPO Cellulose Nanofibers: Graphene Oxide-Based Biohybrids for Water Purification
2017Co-Authors: Chuantao Zhu, Peng Liu, Aji P MathewAbstract:Nanocellulose, graphene oxide (GO), and their combinations there off have attracted great attention for the application of water purification recently because of their unique adsorption capacity, mechanical characteristics, coordination with transition metal ions, surface charge density, and so on. In the current study, (2,2,6,6-tetramethylpiperidine-1-oxylradical) (TEMPO)-mediated oxidized cellulose nanofibers (TOCNF) and GO sheets or graphene oxide nanocolloid (nanoGO) Biohybrids were prepared by vacuum filtration method to obtain self-assembled adsorbents and membranes for water purification. The porous biohybrid structure, studied using advanced microscopy techniques, revealed a unique networking and self-assembling of TOCNF, GO, and nanoGO, driven by the morphology of the GO phase and stabilized by the intermolecular H-bonding between carboxyl groups and hydroxyl groups. The Biohybrids exhibited a promising adsorption capacity toward Cu(II) due to TOCNF and formed a unique “arrested state” in water because of ionic cross-linking between adsorbed Cu(II) and the negatively charged TOCNF and GO phase. The mechanical performance of the freestanding biohybrid membranes investigated using PeakForce Quantative NanoMechanics characterization confirmed the enhanced modulus of the hybrid membrane compared to that of the TOCNF membrane. Besides, the TOCNF+nanoGO membrane shows unique hydrolytic stability and recyclability even under several cycles of adsorption and desorption and strong sonication. This study shows that TOCNF and nanoGO hybrids can generate new water-cleaning membranes with synergistic properties because of their high adsorption capacity, flexibility, hydrolytic stability, and mechanical robustness
Jacques Livage - One of the best experts on this subject based on the ideXlab platform.
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From diatoms to silica-based Biohybrids
Chemical Society Reviews, 2011Co-Authors: Nadine Nassif, Jacques LivageAbstract:This critical review shows that diatoms can be a source of inspiration for the synthesis of advanced nanostructured Biohybrids. These single cell microalgae are living inside a porous silica shell called 'frustule'. Mimicking this model, silica-based Biohybrids have been produced via the so-called sol-gel process. Biomolecules such as proteins, enzymes or antibodies can be trapped within a silica matrix leading to hybrid biosensors and bioreactors. Whole cells remain viable and retain their metabolic activity leading to the formation of living Biohybrids that offer new possibilities in the field of biotechnology and nanomedicine. Diatom frustules exhibit an incredible variety of sophisticated shapes; they can be used as 3D hierarchically structured materials for the realization of sensors, photonic devices or microfluidics. They can also be a model for the bio-templated synthesis of nanostructured materials. Diatom nanotechnology is becoming a new field of research where biologists and materials scientists are working together!
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From diatoms to silica-based Biohybrids.
Chemical Society reviews, 2010Co-Authors: Nadine Nassif, Jacques LivageAbstract:This critical review shows that diatoms can be a source of inspiration for the synthesis of advanced nanostructured Biohybrids. These single cell microalgae are living inside a porous silica shell called ‘frustule’. Mimicking this model, silica-based Biohybrids have been produced via the so-called sol–gel process. Biomolecules such as proteins, enzymes or antibodies can be trapped within a silica matrix leading to hybrid biosensors and bioreactors. Whole cells remain viable and retain their metabolic activity leading to the formation of living Biohybrids that offer new possibilities in the field of biotechnology and nanomedicine. Diatom frustules exhibit an incredible variety of sophisticated shapes; they can be used as 3D hierarchically structured materials for the realization of sensors, photonic devices or microfluidics. They can also be a model for the bio-templated synthesis of nanostructured materials. Diatom nanotechnology is becoming a new field of research where biologists and materials scientists are working together! (125 references)
Chuantao Zhu - One of the best experts on this subject based on the ideXlab platform.
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cellulose nanofiber graphene oxide Biohybrids disclosing the self assembly and copper ion adsorption using advanced microscopy and reaxff simulations
ACS Nano, 2018Co-Authors: Chuantao Zhu, Susanna Monti, Aji P MathewAbstract:The self-assembly of nanocellulose and graphene oxide into highly porous biohybrid materials has inspired the design and synthesis of multifunctional membranes for removing water pollutants. The mechanisms of self-assembly, metal ion capture, and cluster formation on the Biohybrids at the nano- and molecular scales are quite complex. Their elucidation requires evidence from the synergistic combination of experimental data and computational models. The AFM-based microscopy studies of (2,2,6,6-tetramethylpiperidine-1-oxylradical)-mediated oxidized cellulose nanofibers (TOCNFs), graphene oxide (GO), and their biohybrid membranes provide strong, direct evidence of self-assembly; small GO nanoparticles first attach and accumulate along a single TOCNF fiber, while the long, flexible TOCNF filaments wrap around the flat, wide GO planes, thus forming an amorphous and porous biohybrid network. The layered structure of the TOCNFs and GO membrane, derived from the self-assembly and its surface properties before and ...
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Cellulose Nanofiber–Graphene Oxide Biohybrids: Disclosing the Self-Assembly and Copper-Ion Adsorption Using Advanced Microscopy and ReaxFF Simulations
2018Co-Authors: Chuantao Zhu, Susanna Monti, Aji P MathewAbstract:The self-assembly of nanocellulose and graphene oxide into highly porous biohybrid materials has inspired the design and synthesis of multifunctional membranes for removing water pollutants. The mechanisms of self-assembly, metal ion capture, and cluster formation on the Biohybrids at the nano- and molecular scales are quite complex. Their elucidation requires evidence from the synergistic combination of experimental data and computational models. The AFM-based microscopy studies of (2,2,6,6-tetramethylpiperidine-1-oxylradical)-mediated oxidized cellulose nanofibers (TOCNFs), graphene oxide (GO), and their biohybrid membranes provide strong, direct evidence of self-assembly; small GO nanoparticles first attach and accumulate along a single TOCNF fiber, while the long, flexible TOCNF filaments wrap around the flat, wide GO planes, thus forming an amorphous and porous biohybrid network. The layered structure of the TOCNFs and GO membrane, derived from the self-assembly and its surface properties before and after the adsorption of Cu(II), is investigated by advanced microscopy techniques and is further clarified by the ReaxFF molecular dynamics (MD) simulations. The dynamics of the Cu(II)-ion capture by the TOCNF and GO membranes in solution and the ion cluster formation during drying are confirmed by the MD simulations. The results of this multidisciplinary investigation move the research one step forward by disclosing specific aspects of the self-assembly behavior of biospecies and suggesting effective design strategies to control the pore size and robust materials for industrial applications
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tempo cellulose nanofiber graphene oxide Biohybrids disclosing self assembly and cu ii adsorption using advanced microscopy and reaxff molecular dynamics simulations
2018Co-Authors: Chuantao Zhu, Susanna Monti, Aji P MathewAbstract:TEMPO Cellulose Nanofiber - Graphene Oxide Biohybrids : Disclosing Self-Assembly and Cu(II) Adsorption using Advanced Microscopy and ReaxFF Molecular Dynamics Simulations
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Self-Assembled TEMPO Cellulose Nanofibers: Graphene Oxide-Based Biohybrids for Water Purification
ACS applied materials & interfaces, 2017Co-Authors: Chuantao Zhu, Peng Liu, Aji P MathewAbstract:Nanocellulose, graphene oxide (GO), and their combinations there off have attracted great attention for the application of water purification recently because of their unique adsorption capacity, mechanical characteristics, coordination with transition metal ions, surface charge density, and so on. In the current study, (2,2,6,6-tetramethylpiperidine-1-oxylradical) (TEMPO)-mediated oxidized cellulose nanofibers (TOCNF) and GO sheets or graphene oxide nanocolloid (nanoGO) Biohybrids were prepared by vacuum filtration method to obtain self-assembled adsorbents and membranes for water purification. The porous biohybrid structure, studied using advanced microscopy techniques, revealed a unique networking and self-assembling of TOCNF, GO, and nanoGO, driven by the morphology of the GO phase and stabilized by the intermolecular H-bonding between carboxyl groups and hydroxyl groups. The Biohybrids exhibited a promising adsorption capacity toward Cu(II) due to TOCNF and formed a unique “arrested state” in water b...
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Self-Assembled TEMPO Cellulose Nanofibers: Graphene Oxide-Based Biohybrids for Water Purification
2017Co-Authors: Chuantao Zhu, Peng Liu, Aji P MathewAbstract:Nanocellulose, graphene oxide (GO), and their combinations there off have attracted great attention for the application of water purification recently because of their unique adsorption capacity, mechanical characteristics, coordination with transition metal ions, surface charge density, and so on. In the current study, (2,2,6,6-tetramethylpiperidine-1-oxylradical) (TEMPO)-mediated oxidized cellulose nanofibers (TOCNF) and GO sheets or graphene oxide nanocolloid (nanoGO) Biohybrids were prepared by vacuum filtration method to obtain self-assembled adsorbents and membranes for water purification. The porous biohybrid structure, studied using advanced microscopy techniques, revealed a unique networking and self-assembling of TOCNF, GO, and nanoGO, driven by the morphology of the GO phase and stabilized by the intermolecular H-bonding between carboxyl groups and hydroxyl groups. The Biohybrids exhibited a promising adsorption capacity toward Cu(II) due to TOCNF and formed a unique “arrested state” in water because of ionic cross-linking between adsorbed Cu(II) and the negatively charged TOCNF and GO phase. The mechanical performance of the freestanding biohybrid membranes investigated using PeakForce Quantative NanoMechanics characterization confirmed the enhanced modulus of the hybrid membrane compared to that of the TOCNF membrane. Besides, the TOCNF+nanoGO membrane shows unique hydrolytic stability and recyclability even under several cycles of adsorption and desorption and strong sonication. This study shows that TOCNF and nanoGO hybrids can generate new water-cleaning membranes with synergistic properties because of their high adsorption capacity, flexibility, hydrolytic stability, and mechanical robustness
Wei Zhou - One of the best experts on this subject based on the ideXlab platform.
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star shaped polypeptide glycopolymer Biohybrids synthesis self assembly biomolecular recognition and controlled drug release behavior
Journal of Polymer Science Part A, 2009Co-Authors: Shuo Qiu, Hui Huang, Wei Zhou, Xiaohui Dai, Changming DongAbstract:Star-shaped polypeptide/glycopolymer Biohybrids composed of poly(γ- benzyl L-glutamate) and poly(D-gluconamidoethyl methacrylate), exhibiting controlled molecular weights and low polydispersities, were synthesized by the combination of ring-opening polymerization of γ-benzyl-L-glutamate N-carboxyanhydride and the direct atom transfer radical polymerization of unprotected D-gluconamidoethyl methacrylate glycomonomer. These Biohybrids were characterized in detail by means of FTIR, 1H NMR, gel permeation chromatography, differential scanning calorimetry, and wide angle X-ray diffraction. Independent of weight fraction of hydrophilic glycopolymer segment, the Biohybrids self-assembled into large spherical micelles in aqueous solution, which had a helical polypeptide core surrounded by a multivalent glycopolymer shell. The deprotected poly(L-glutamate)/glycopolymer hybrid exhibited a pH-sensitive self-assembly behavior, and the average size of the nanoparticles decreased gradually over the aqueous pH value. Moreover, whatever these Biohybrids existed in unimolecular level or glycopolymer-surfaced nanoparticles, they had specific biomolecular recognition with Concanavalin A compared with bovine serum albumin. Furthermore, star-shaped Biohybrids showed a higher doxorubicin loading efficiency and longer drug-release time than linear analogues. This potentially provides a platform for fabricating targeted anticancer drug delivery system and studying glycoprotein functions in vitro. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 47: 2009–2023, 2009
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star shaped polypeptide glycopolymer Biohybrids synthesis self assembly biomolecular recognition and controlled drug release behavior part a polymer chemistry
Journal of Polymer Science, 2009Co-Authors: Shuo Qiu, Hui Huang, Wei Zhou, Xiaohui Dai, Changming DongAbstract:Star-shaped polypeptide/glycopolymer Biohybrids composed of poly(γ- benzyl L-glutamate) and poly(D-gluconamidoethyl methacrylate), exhibiting controlled molecular weights and low polydispersities, were synthesized by the combination of ring-opening polymerization of γ-benzyl-L-glutamate N-carboxyanhydride and the direct atom transfer radical polymerization of unprotected D-gluconamidoethyl methacrylate glycomonomer. These Biohybrids were characterized in detail by means of FTIR, ¹H NMR, gel permeation chromatography, differential scanning calorimetry, and wide angle X-ray diffraction. Independent of weight fraction of hydrophilic glycopolymer segment, the Biohybrids self-assembled into large spherical micelles in aqueous solution, which had a helical polypeptide core surrounded by a multivalent glycopolymer shell. The deprotected poly(L-glutamate)/glycopolymer hybrid exhibited a pH-sensitive self-assembly behavior, and the average size of the nanoparticles decreased gradually over the aqueous pH value. Moreover, whatever these Biohybrids existed in unimolecular level or glycopolymer-surfaced nanoparticles, they had specific biomolecular recognition with Concanavalin A compared with bovine serum albumin. Furthermore, star-shaped Biohybrids showed a higher doxorubicin loading efficiency and longer drug-release time than linear analogues. This potentially provides a platform for fabricating targeted anticancer drug delivery system and studying glycoprotein functions in vitro.
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Biodegradable and Biomimetic Poly(ε‐caprolactone)/Poly(lactobionamidoethyl methacrylate) Biohybrids: Synthesis, Lactose‐Installed Nanoparticles and Recognition Properties
Macromolecular bioscience, 2008Co-Authors: Wei Zhou, Xiaohui Dai, Changming DongAbstract:Biodegradable and biomimetic SPCL-PLAMA Biohybrids were synthesized via ATRP and characterized by FT-IR, 1 H NMR, GPC and DSC. Biohybrids with small PDI were obtained, and the block length of the PLAMA glycopolymer could be varied linearly by the varying the molar ratio of glycomonomer to macroinitiator. The outer PLAMA glycopolymer restrained the crystallization of inner PCL segments. The self-assembly properties of amphiphilic Biohybrids were studied. Lactose-installed aggregates were fabricated in aqueous solution; they changed from spherical micelles to vesicles with increasing weight fraction of hydrophobic PCL. The SPCL-PLAMA Biohybrids showed specific recognition for RCA 120 lectin.
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biodegradable and biomimetic poly e caprolactone poly lactobionamidoethyl methacrylate Biohybrids synthesis lactose installed nanoparticles and recognition properties
Macromolecular Bioscience, 2008Co-Authors: Wei Zhou, Xiaohui Dai, Changming DongAbstract:Biodegradable and biomimetic SPCL-PLAMA Biohybrids were synthesized via ATRP and characterized by FT-IR, 1 H NMR, GPC and DSC. Biohybrids with small PDI were obtained, and the block length of the PLAMA glycopolymer could be varied linearly by the varying the molar ratio of glycomonomer to macroinitiator. The outer PLAMA glycopolymer restrained the crystallization of inner PCL segments. The self-assembly properties of amphiphilic Biohybrids were studied. Lactose-installed aggregates were fabricated in aqueous solution; they changed from spherical micelles to vesicles with increasing weight fraction of hydrophobic PCL. The SPCL-PLAMA Biohybrids showed specific recognition for RCA 120 lectin.