The Experts below are selected from a list of 267 Experts worldwide ranked by ideXlab platform

Luciano Milanesi - One of the best experts on this subject based on the ideXlab platform.

  • Web services and workflow management for Biological Resources.
    BMC bioinformatics, 2005
    Co-Authors: Paolo Romano, Domenico Marra, Luciano Milanesi
    Abstract:

    The completion of the Human Genome Project has resulted in large quantities of Biological data which are proving difficult to manage and integrate effectively. There is a need for a system that is able to automate accesses to remote sites and to "understand" the information that it is managing in order to link data properly. Workflow management systems combined with Web Services are promising Information and Communication Technologies (ICT) tools. Some have already been proposed and are being increasingly applied to the biomedical domain, especially as many biology-related Web Services are now becoming available. Information on Biological Resources and on genomic sequences mutations are two examples of very specialized datasets that are useful for specific research domains. The architecture of a system that is able to access and execute predefined workflows is presented in this paper. Web Services allowing access to the IARC TP53 Mutation Database and CABRI catalogues of Biological Resources have been implemented and are available on-line. Example workflows which retrieve data from these Web Services have also been created and are available on-line. We present a general architecture and some building blocks for the implementation of a system that is able to remotely execute workflows of biomedical interest and show how this approach can effectively produce useful outputs. The further development and implementation of Web Services allowing access to an exhaustive set of biomedical databases and the creation of effective and useful workflows will improve the automation of in-silico analysis.

  • Web services and workflow management for Biological Resources
    BMC Bioinformatics, 2005
    Co-Authors: Paolo Romano, Domenico Marra, Luciano Milanesi
    Abstract:

    Abstract Backgorund The completion of the Human Genome Project has resulted in large quantities of Biological data which are proving difficult to manage and integrate effectively. There is a need for a system that is able to automate accesses to remote sites and to "understand" the information that it is managing in order to link data properly. Workflow management systems combined with Web Services are promising Information and Communication Technologies (ICT) tools. Some have already been proposed and are being increasingly applied to the biomedical domain, especially as many biology-related Web Services are now becoming available. Information on Biological Resources and on genomic sequences mutations are two examples of very specialized datasets that are useful for specific research domains. Results The architecture of a system that is able to access and execute predefined workflows is presented in this paper. Web Services allowing access to the IARC TP53 Mutation Database and CABRI catalogues of Biological Resources have been implemented and are available on-line. Example workflows which retrieve data from these Web Services have also been created and are available on-line. Conclusion We present a general architecture and some building blocks for the implementation of a system that is able to remotely execute workflows of biomedical interest and show how this approach can effectively produce useful outputs. The further development and implementation of Web Services allowing access to an exhaustive set of biomedical databases and the creation of effective and useful workflows will improve the automation of in-silico analysis.

Paolo Romano - One of the best experts on this subject based on the ideXlab platform.

  • Web services and workflow management for Biological Resources.
    BMC bioinformatics, 2005
    Co-Authors: Paolo Romano, Domenico Marra, Luciano Milanesi
    Abstract:

    The completion of the Human Genome Project has resulted in large quantities of Biological data which are proving difficult to manage and integrate effectively. There is a need for a system that is able to automate accesses to remote sites and to "understand" the information that it is managing in order to link data properly. Workflow management systems combined with Web Services are promising Information and Communication Technologies (ICT) tools. Some have already been proposed and are being increasingly applied to the biomedical domain, especially as many biology-related Web Services are now becoming available. Information on Biological Resources and on genomic sequences mutations are two examples of very specialized datasets that are useful for specific research domains. The architecture of a system that is able to access and execute predefined workflows is presented in this paper. Web Services allowing access to the IARC TP53 Mutation Database and CABRI catalogues of Biological Resources have been implemented and are available on-line. Example workflows which retrieve data from these Web Services have also been created and are available on-line. We present a general architecture and some building blocks for the implementation of a system that is able to remotely execute workflows of biomedical interest and show how this approach can effectively produce useful outputs. The further development and implementation of Web Services allowing access to an exhaustive set of biomedical databases and the creation of effective and useful workflows will improve the automation of in-silico analysis.

  • The Role of Informatics in the Coordinated Management of Biological Resources Collections
    Applied Bioinformatics, 2005
    Co-Authors: Paolo Romano, Manfred Kracht, Maria Assunta Manniello, Gerrit Stegehuis, Dagmar Fritze
    Abstract:

    The term ‘Biological Resources’ is applied to the living Biological material collected, held and catalogued in culture collections: bacterial and fungal cultures; animal, human and plant cells; viruses; and isolated genetic material. A wealth of information on these materials has been accumulated in culture collections, and most of this information is accessible. Digitalisation of data has reached a high level; however, information is still dispersed. Individual and coordinated approaches have been initiated to improve accessibility of Biological resource centres, their holdings and related information through the Internet. These approaches cover subjects such as standardisation of data handling and data accessibility, and standardisation and quality control of laboratory procedures. This article reviews some of the most important initiatives implemented so far, as well as the most recent achievements. It also discusses the possible improvements that could be achieved by adopting new communication standards and technologies, such as web services, in view of a deeper and more fruitful integration of Biological Resources information in the bioinformatics network environment.

  • Web services and workflow management for Biological Resources
    BMC Bioinformatics, 2005
    Co-Authors: Paolo Romano, Domenico Marra, Luciano Milanesi
    Abstract:

    Abstract Backgorund The completion of the Human Genome Project has resulted in large quantities of Biological data which are proving difficult to manage and integrate effectively. There is a need for a system that is able to automate accesses to remote sites and to "understand" the information that it is managing in order to link data properly. Workflow management systems combined with Web Services are promising Information and Communication Technologies (ICT) tools. Some have already been proposed and are being increasingly applied to the biomedical domain, especially as many biology-related Web Services are now becoming available. Information on Biological Resources and on genomic sequences mutations are two examples of very specialized datasets that are useful for specific research domains. Results The architecture of a system that is able to access and execute predefined workflows is presented in this paper. Web Services allowing access to the IARC TP53 Mutation Database and CABRI catalogues of Biological Resources have been implemented and are available on-line. Example workflows which retrieve data from these Web Services have also been created and are available on-line. Conclusion We present a general architecture and some building blocks for the implementation of a system that is able to remotely execute workflows of biomedical interest and show how this approach can effectively produce useful outputs. The further development and implementation of Web Services allowing access to an exhaustive set of biomedical databases and the creation of effective and useful workflows will improve the automation of in-silico analysis.

Domenico Marra - One of the best experts on this subject based on the ideXlab platform.

  • Web services and workflow management for Biological Resources.
    BMC bioinformatics, 2005
    Co-Authors: Paolo Romano, Domenico Marra, Luciano Milanesi
    Abstract:

    The completion of the Human Genome Project has resulted in large quantities of Biological data which are proving difficult to manage and integrate effectively. There is a need for a system that is able to automate accesses to remote sites and to "understand" the information that it is managing in order to link data properly. Workflow management systems combined with Web Services are promising Information and Communication Technologies (ICT) tools. Some have already been proposed and are being increasingly applied to the biomedical domain, especially as many biology-related Web Services are now becoming available. Information on Biological Resources and on genomic sequences mutations are two examples of very specialized datasets that are useful for specific research domains. The architecture of a system that is able to access and execute predefined workflows is presented in this paper. Web Services allowing access to the IARC TP53 Mutation Database and CABRI catalogues of Biological Resources have been implemented and are available on-line. Example workflows which retrieve data from these Web Services have also been created and are available on-line. We present a general architecture and some building blocks for the implementation of a system that is able to remotely execute workflows of biomedical interest and show how this approach can effectively produce useful outputs. The further development and implementation of Web Services allowing access to an exhaustive set of biomedical databases and the creation of effective and useful workflows will improve the automation of in-silico analysis.

  • Web services and workflow management for Biological Resources
    BMC Bioinformatics, 2005
    Co-Authors: Paolo Romano, Domenico Marra, Luciano Milanesi
    Abstract:

    Abstract Backgorund The completion of the Human Genome Project has resulted in large quantities of Biological data which are proving difficult to manage and integrate effectively. There is a need for a system that is able to automate accesses to remote sites and to "understand" the information that it is managing in order to link data properly. Workflow management systems combined with Web Services are promising Information and Communication Technologies (ICT) tools. Some have already been proposed and are being increasingly applied to the biomedical domain, especially as many biology-related Web Services are now becoming available. Information on Biological Resources and on genomic sequences mutations are two examples of very specialized datasets that are useful for specific research domains. Results The architecture of a system that is able to access and execute predefined workflows is presented in this paper. Web Services allowing access to the IARC TP53 Mutation Database and CABRI catalogues of Biological Resources have been implemented and are available on-line. Example workflows which retrieve data from these Web Services have also been created and are available on-line. Conclusion We present a general architecture and some building blocks for the implementation of a system that is able to remotely execute workflows of biomedical interest and show how this approach can effectively produce useful outputs. The further development and implementation of Web Services allowing access to an exhaustive set of biomedical databases and the creation of effective and useful workflows will improve the automation of in-silico analysis.

Malathi Lakshmikumaran - One of the best experts on this subject based on the ideXlab platform.

  • Protecting Traditional Knowledge Related to Biological Resources: Is Scientific Research Going to Become More Bureaucratized?
    Cold Spring Harbor perspectives in medicine, 2015
    Co-Authors: Prashant Reddy, Malathi Lakshmikumaran
    Abstract:

    For the past several decades, there has been a world debate on the need for protecting traditional knowledge. A global treaty appears to be a distant reality. Of more immediate concern are the steps taken by the global community to protect access to Biological Resources in the name of protecting traditional knowledge. The Indian experience with implementing the Convention on Biological Diversity has created substantial legal uncertainty in collaborative scientific research between Indians and foreigners apart from bureaucratizing the entire process of scientific research, especially with regard to filing of applications for intellectual property rights. The issue therefore is whether the world needs to better balance the needs of the scientific community with the rights of those who have access to traditional knowledge.

Prashant Reddy - One of the best experts on this subject based on the ideXlab platform.

  • Protecting Traditional Knowledge Related to Biological Resources: Is Scientific Research Going to Become More Bureaucratized?
    Cold Spring Harbor perspectives in medicine, 2015
    Co-Authors: Prashant Reddy, Malathi Lakshmikumaran
    Abstract:

    For the past several decades, there has been a world debate on the need for protecting traditional knowledge. A global treaty appears to be a distant reality. Of more immediate concern are the steps taken by the global community to protect access to Biological Resources in the name of protecting traditional knowledge. The Indian experience with implementing the Convention on Biological Diversity has created substantial legal uncertainty in collaborative scientific research between Indians and foreigners apart from bureaucratizing the entire process of scientific research, especially with regard to filing of applications for intellectual property rights. The issue therefore is whether the world needs to better balance the needs of the scientific community with the rights of those who have access to traditional knowledge.