The Experts below are selected from a list of 13332 Experts worldwide ranked by ideXlab platform
Wenwen Tung - One of the best experts on this subject based on the ideXlab platform.
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entropy measures for Biological Signal analyses
Nonlinear Dynamics, 2012Co-Authors: Jing Hu, Wenwen TungAbstract:Entropies are among the most popular and promising complexity measures for Biological Signal analyses. Various types of entropy measures exist, including Shannon entropy, Kolmogorov entropy, approximate entropy (ApEn), sample entropy (SampEn), multiscale entropy (MSE), and so on. A fundamental question is which entropy should be chosen for a specific Biological application. To solve this issue, we focus on scaling laws of different entropy measures and introduce an ensemble forecasting framework to find the connections among them. One critical component of the ensemble forecasting framework is the scale-dependent Lyapunov exponent (SDLE), whose scaling behavior is found to be the richest among all the entropy measures. In fact, SDLE contains all the essential information of other entropy measures, and can act as a unifying multiscale complexity measure. Furthermore, SDLE has a unique scale separation property to aptly deal with nonstationarity and characterize high-dimensional and intermittent chaos. Therefore, SDLE can often be the first choice for exploratory studies in biology. The effectiveness of SDLE and the ensemble forecasting framework is illustrated by considering epileptic seizure detection from EEG.
Kwang Suk Park - One of the best experts on this subject based on the ideXlab platform.
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nonintrusive Biological Signal monitoring in a car to evaluate a driver s stress and health state
Telemedicine Journal and E-health, 2009Co-Authors: Hyun Jae Baek, Jong Min Choi, Kwang Suk ParkAbstract:Nonintrusive monitoring of a driver's physiological Signals was introduced and evaluated in a car as a test of extending the concept of ubiquitous healthcare to vehicles. Electrocardiogram, photoplethysmogram, galvanic skin response, and respiration were measured in the ubiquitous healthcare car (U-car) using nonintrusively installed sensors on the steering wheel, driver's seat, and seat belt. Measured Signals were transmitted to the embedded computer via Bluetooth(R) communication and processed. We collected and analyzed physiological Signals during driving in order to estimate a driver's stress state while using this system. In order to compare the effect of stress on physical and mental conditions, two categories of stresses were defined. Experimental results show that a driver's physiological Signals were measured with acceptable quality for analysis without interrupting driving, and they were changed meaningfully due to elicited stress. This nonintrusive monitoring can be used to evaluate a driver's state of health and stress. Language: en
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Nonintrusive measurement of Biological Signals for ubiquitous healthcare
Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, 2009Co-Authors: Kwang Suk ParkAbstract:In order to monitor Biological Signals during our daily lives for ubiquitous healthcare, nonintrusive Biological Signal monitoring methods have been developed. Without contacting sensors and connecting wires to the subjects, the Biological Signals are monitored using specially designed methods. ECG is measured using capacitive coupling over clothes and PPG is measured nonintrusively during ordinary activities. Blood pressure is also estimated from ECG and PPG by calculating pulse arrival time (PAT). These methods can be applied to evaluate the health levels of subjects without intervening in their ordinary daily activities.
Jim A Rogers - One of the best experts on this subject based on the ideXlab platform.
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emergent decision making in Biological Signal transduction networks
Proceedings of the National Academy of Sciences of the United States of America, 2008Co-Authors: Tomas Helikar, John Konvalina, Jack Heidel, Jim A RogersAbstract:The complexity of biochemical intracellular Signal transduction networks has led to speculation that the high degree of interconnectivity that exists in these networks transforms them into an information processing network. To test this hypothesis directly, a large scale model was created with the logical mechanism of each node described completely to allow simulation and dynamical analysis. Exposing the network to tens of thousands of random combinations of inputs and analyzing the combined dynamics of multiple outputs revealed a robust system capable of clustering widely varying input combinations into equivalence classes of Biologically relevant cellular responses. This capability was nontrivial in that the network performed sharp, nonfuzzy classifications even in the face of added noise, a hallmark of real-world decision-making.
Jing Hu - One of the best experts on this subject based on the ideXlab platform.
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entropy measures for Biological Signal analyses
Nonlinear Dynamics, 2012Co-Authors: Jing Hu, Wenwen TungAbstract:Entropies are among the most popular and promising complexity measures for Biological Signal analyses. Various types of entropy measures exist, including Shannon entropy, Kolmogorov entropy, approximate entropy (ApEn), sample entropy (SampEn), multiscale entropy (MSE), and so on. A fundamental question is which entropy should be chosen for a specific Biological application. To solve this issue, we focus on scaling laws of different entropy measures and introduce an ensemble forecasting framework to find the connections among them. One critical component of the ensemble forecasting framework is the scale-dependent Lyapunov exponent (SDLE), whose scaling behavior is found to be the richest among all the entropy measures. In fact, SDLE contains all the essential information of other entropy measures, and can act as a unifying multiscale complexity measure. Furthermore, SDLE has a unique scale separation property to aptly deal with nonstationarity and characterize high-dimensional and intermittent chaos. Therefore, SDLE can often be the first choice for exploratory studies in biology. The effectiveness of SDLE and the ensemble forecasting framework is illustrated by considering epileptic seizure detection from EEG.
Alexander S Mikhailov - One of the best experts on this subject based on the ideXlab platform.
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self correcting networks function robustness and motif distributions in Biological Signal processing
Chaos, 2008Co-Authors: Pablo Kaluza, Martin Vingron, Alexander S MikhailovAbstract:Statistical properties of large ensembles of networks, all designed to have the same functions of Signal processing, but robust against different kinds of perturbations, are analyzed. We find that robustness against noise and random local damage plays a dominant role in determining motif distributions of networks and may underlie their classification into network superfamilies.
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design and statistical properties of robust functional networks a model study of Biological Signal transduction
Physical Review E, 2007Co-Authors: Pablo Kaluza, Mads Ipsen, Martin Vingron, Alexander S MikhailovAbstract:A simple flow network model of Biological Signal transduction is investigated. Networks with prescribed Signal processing functions, robust against random node or link removals, are designed through an evolutionary optimization process. Statistical properties of large ensembles of such networks, including their characteristic motif distributions, are determined. Our analysis suggests that robustness against link removals plays the principal role in the architecture of real Signal transduction networks and developmental genetic transcription networks.