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Bitemporal Hemianopsia

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Elisabeth J. Rushing – 1st expert on this subject based on the ideXlab platform

  • synchronous pituitary adenoma and pituicytoma
    Human Pathology, 2016
    Co-Authors: Marian Christoph Neidert, Henning Leske, Jankarl Burkhardt, Spyros Kollias, David Capper, Daniel Schrimpf, Luca Regli, Elisabeth J. Rushing

    Abstract:

    Pituicytoma is a rare benign neoplasm arising in the sellar region, usually found in the posterior lobe and/or pituitary stalk. Here, we report the case of a 67-year-old woman who presented with Bitemporal Hemianopsia and visual impairment accompanied by mildly elevated prolactin. Pathologic and molecular examination of the tissue removed transsphenoidally revealed 2 distinct tumors: pituitary adenoma and pituicytoma. To the best of our knowledge, histologically proven pituicytoma and pituitary adenoma have never been reported together.

Patrick J. Codd – 2nd expert on this subject based on the ideXlab platform

  • transnasal transsphenoidal elevation of optic chiasm in secondary empty sella syndrome following prolactinoma treatment
    World Neurosurgery, 2018
    Co-Authors: Mary Inping Huang Cobb, Matthew G Crowson, Rachael A Mintzcole, Aatif M Husain, Miles Berger, David W Jang, Patrick J. Codd

    Abstract:

    Background Prolactinomas are typically treated nonsurgically with a dopamine agonist. Once the tumor shrinks, adjacent eloquent structures, such as the optic apparatus, can become skeletonized and herniate into the dilated parasellar space. Case Description A 48-year-old man with a prolactin-secreting macroadenoma treated with cabergoline presented with progressive Bitemporal Hemianopsia. Magnetic resonance imaging showed no recurrence of disease and a stretched optic chiasm herniating into an empty sella. Elevation of the optic chiasm via a transnasal transsphenoidal approach with ALLODERM graft and septal cartilage strut was performed. The patient was discharged home the next day with significant improvement in vision; magnetic resonance imaging showed interval elevation of the optic chiasm. Conclusions We review secondary empty sella syndrome and discuss surgical strategies for optic chiasmapexy.

David J. Gross – 3rd expert on this subject based on the ideXlab platform

  • Pituitary Macroadenoma Secreting Thyrotropin and Growth Hormone: Remission of Bihormonal Hypersecretion in Response to Lanreotide Therapy
    Pituitary, 2001
    Co-Authors: Ilan Shimon, Dvora Nass, David J. Gross

    Abstract:

    We report a case of mixed TSH- and GH-secreting pituitary adenoma in a 60-year-old female patient. She presented with Bitemporal Hemianopsia and large invasive pituitary macroadenoma. Blood hormone levels determinations revealed elevated thyroid hormones, TSH, and IGF-1 with a relatively low GH. The patient had a mild acromegalic appearance but did not display signs of thyrotoxicosis or goiter. She underwent two pituitary surgical procedures followed by radiotherapy, but despite treatment was still hormonally active. Pathological examination of the resected tumor immunostained positively for both TSH and GH. The patient was subsequently treated with injections of lanreotide, a depot long-acting somatostatin analog, resulting in suppression of blood TSH, thyroid hormones, α-subunits, GH and IGF-1.