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Blood Coagulation

The Experts below are selected from a list of 252 Experts worldwide ranked by ideXlab platform

Leonidas G. Bachas – 1st expert on this subject based on the ideXlab platform

  • monitoring Blood Coagulation with magnetoelastic sensors
    Biosensors and Bioelectronics, 2003
    Co-Authors: Libby G. Puckett, Gary Barrett, D. Kouzoudis, Craig A. Grimes, Leonidas G. Bachas

    Abstract:

    The determination of Blood Coagulation time is an essential part of monitoring therapeutic anticoagulants. Standard methodologies for the measurement of Blood clotting time require dedicated personnel and involve Blood sampling procedures. A new method based on magnetoelastic sensors has been employed for the monitoring of Blood Coagulation. The ribbon-like magnetoelastic sensor oscillates at a fundamental frequency, which shifts linearly in response to applied mass loads or a fixed mass load of changing elasticity. The magnetoelastic sensors emit magnetic flux, which can be detected by a remotely located pick-up coil, so that no direct physical connections are required. During Blood Coagulation, the viscosity of Blood changes due to the formation of a soft fibrin clot. In turn, this change in viscosity shifts the characteristic resonance frequency of the magnetoelastic sensor enabling real-time continuous monitoring of this biological event. By monitoring the signal output as a function of time, a distinct Blood clotting profile can be seen. The relatively low cost of the magnetoelastic ribbons enables their use as disposable sensors. This, along with the reduced volume of Blood required, make the magnetoelastic sensors well suited for at-home and point-of-care testing devices.

  • Monitoring Blood Coagulation with magnetoelastic sensors
    Biosensors and Bioelectronics, 2003
    Co-Authors: Libby G. Puckett, Gary Barrett, D. Kouzoudis, Craig A. Grimes, Craig Grimes, Leonidas G. Bachas

    Abstract:

    The determination of Blood Coagulation time is an essential part of monitoring therapeutic anticoagulants. Standard methodologies for the measurement of Blood clotting time require dedicated personnel and involve Blood sampling procedures. A new method based on magnetoelastic sensors has been employed for the monitoring of Blood Coagulation. The ribbon-like magnetoelastic sensor oscillates at a fundamental frequency, which shifts linearly in response to applied mass loads or a fixed mass load of changing elasticity. The magnetoelastic sensors emit magnetic flux, which can be detected by a remotely located pick-up coil, so that no direct physical connections are required. During Blood Coagulation, the viscosity of Blood changes due to the formation of a soft fibrin clot. In turn, this change in viscosity shifts the characteristic resonance frequency of the magnetoelastic sensor enabling real-time continuous monitoring of this biological event. By monitoring the signal output as a function of time, a distinct Blood clotting profile can be seen. The relatively low cost of the magnetoelastic ribbons enables their use as disposable sensors. This, along with the reduced volume of Blood required, make the magnetoelastic sensors well suited for at-home and point-of-care testing devices. © 2003 Elsevier Science B.V. All rights reserved.

Libby G. Puckett – 2nd expert on this subject based on the ideXlab platform

  • monitoring Blood Coagulation with magnetoelastic sensors
    Biosensors and Bioelectronics, 2003
    Co-Authors: Libby G. Puckett, Gary Barrett, D. Kouzoudis, Craig A. Grimes, Leonidas G. Bachas

    Abstract:

    The determination of Blood Coagulation time is an essential part of monitoring therapeutic anticoagulants. Standard methodologies for the measurement of Blood clotting time require dedicated personnel and involve Blood sampling procedures. A new method based on magnetoelastic sensors has been employed for the monitoring of Blood Coagulation. The ribbon-like magnetoelastic sensor oscillates at a fundamental frequency, which shifts linearly in response to applied mass loads or a fixed mass load of changing elasticity. The magnetoelastic sensors emit magnetic flux, which can be detected by a remotely located pick-up coil, so that no direct physical connections are required. During Blood Coagulation, the viscosity of Blood changes due to the formation of a soft fibrin clot. In turn, this change in viscosity shifts the characteristic resonance frequency of the magnetoelastic sensor enabling real-time continuous monitoring of this biological event. By monitoring the signal output as a function of time, a distinct Blood clotting profile can be seen. The relatively low cost of the magnetoelastic ribbons enables their use as disposable sensors. This, along with the reduced volume of Blood required, make the magnetoelastic sensors well suited for at-home and point-of-care testing devices.

  • Monitoring Blood Coagulation with magnetoelastic sensors
    Biosensors and Bioelectronics, 2003
    Co-Authors: Libby G. Puckett, Gary Barrett, D. Kouzoudis, Craig A. Grimes, Craig Grimes, Leonidas G. Bachas

    Abstract:

    The determination of Blood Coagulation time is an essential part of monitoring therapeutic anticoagulants. Standard methodologies for the measurement of Blood clotting time require dedicated personnel and involve Blood sampling procedures. A new method based on magnetoelastic sensors has been employed for the monitoring of Blood Coagulation. The ribbon-like magnetoelastic sensor oscillates at a fundamental frequency, which shifts linearly in response to applied mass loads or a fixed mass load of changing elasticity. The magnetoelastic sensors emit magnetic flux, which can be detected by a remotely located pick-up coil, so that no direct physical connections are required. During Blood Coagulation, the viscosity of Blood changes due to the formation of a soft fibrin clot. In turn, this change in viscosity shifts the characteristic resonance frequency of the magnetoelastic sensor enabling real-time continuous monitoring of this biological event. By monitoring the signal output as a function of time, a distinct Blood clotting profile can be seen. The relatively low cost of the magnetoelastic ribbons enables their use as disposable sensors. This, along with the reduced volume of Blood required, make the magnetoelastic sensors well suited for at-home and point-of-care testing devices. © 2003 Elsevier Science B.V. All rights reserved.

Craig A. Grimes – 3rd expert on this subject based on the ideXlab platform

  • monitoring Blood Coagulation with magnetoelastic sensors
    Biosensors and Bioelectronics, 2003
    Co-Authors: Libby G. Puckett, Gary Barrett, D. Kouzoudis, Craig A. Grimes, Leonidas G. Bachas

    Abstract:

    The determination of Blood Coagulation time is an essential part of monitoring therapeutic anticoagulants. Standard methodologies for the measurement of Blood clotting time require dedicated personnel and involve Blood sampling procedures. A new method based on magnetoelastic sensors has been employed for the monitoring of Blood Coagulation. The ribbon-like magnetoelastic sensor oscillates at a fundamental frequency, which shifts linearly in response to applied mass loads or a fixed mass load of changing elasticity. The magnetoelastic sensors emit magnetic flux, which can be detected by a remotely located pick-up coil, so that no direct physical connections are required. During Blood Coagulation, the viscosity of Blood changes due to the formation of a soft fibrin clot. In turn, this change in viscosity shifts the characteristic resonance frequency of the magnetoelastic sensor enabling real-time continuous monitoring of this biological event. By monitoring the signal output as a function of time, a distinct Blood clotting profile can be seen. The relatively low cost of the magnetoelastic ribbons enables their use as disposable sensors. This, along with the reduced volume of Blood required, make the magnetoelastic sensors well suited for at-home and point-of-care testing devices.

  • Monitoring Blood Coagulation with magnetoelastic sensors
    Biosensors and Bioelectronics, 2003
    Co-Authors: Libby G. Puckett, Gary Barrett, D. Kouzoudis, Craig A. Grimes, Craig Grimes, Leonidas G. Bachas

    Abstract:

    The determination of Blood Coagulation time is an essential part of monitoring therapeutic anticoagulants. Standard methodologies for the measurement of Blood clotting time require dedicated personnel and involve Blood sampling procedures. A new method based on magnetoelastic sensors has been employed for the monitoring of Blood Coagulation. The ribbon-like magnetoelastic sensor oscillates at a fundamental frequency, which shifts linearly in response to applied mass loads or a fixed mass load of changing elasticity. The magnetoelastic sensors emit magnetic flux, which can be detected by a remotely located pick-up coil, so that no direct physical connections are required. During Blood Coagulation, the viscosity of Blood changes due to the formation of a soft fibrin clot. In turn, this change in viscosity shifts the characteristic resonance frequency of the magnetoelastic sensor enabling real-time continuous monitoring of this biological event. By monitoring the signal output as a function of time, a distinct Blood clotting profile can be seen. The relatively low cost of the magnetoelastic ribbons enables their use as disposable sensors. This, along with the reduced volume of Blood required, make the magnetoelastic sensors well suited for at-home and point-of-care testing devices. © 2003 Elsevier Science B.V. All rights reserved.