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Brian M Mercer - One of the best experts on this subject based on the ideXlab platform.

  • Blood Volume Determination in obese and normal-weight gravidas: the hydroxyethyl starch method.
    American journal of obstetrics and gynecology, 2015
    Co-Authors: Laura K Vricella, Judette M Louis, Edward Chien, Brian M Mercer
    Abstract:

    The impact of obesity on maternal Blood Volume in pregnancy has not been reported. We compared the Blood Volumes of obese and normal-weight gravidas using a validated hydroxyethyl starch (HES) dilution technique for Blood Volume estimation. Blood Volumes were estimated in 30 normal-weight (pregravid body mass index [BMI] <25 kg/m(2)) and 30 obese (pregravid BMI >35 kg/m(2)) gravidas >34 weeks' gestation using a modified HES dilution technique. Blood samples obtained before and 10 minutes after HES injection were analyzed for plasma glucose concentrations after acid hydrolysis of HES. Blood Volume was calculated from the difference between glucose concentrations measured in hydrolyzed plasma. Obese gravidas had higher pregravid and visit BMI (mean [SD]): pregravid (41 [4] vs 22 [2] kg/m(2), P = .001); visit (42 [4] vs 27 [2] kg/m(2), P = .001), but lower weight gain (5 [7] vs 12 [4] kg, P = .001) than normal-weight women. Obese gravidas had similar estimated total Blood Volume to normal-weight women (8103 ± 2452 vs 6944 ± 2830 mL, P = .1), but lower Blood Volume per kilogram weight (73 ± 22 vs 95 ± 30 mL/kg, P = .007). Obese gravidas have similar circulating Blood Volume, but lower Blood Volume per kilogram body weight, than normal-weight gravidas near term. Copyright © 2015 Elsevier Inc. All rights reserved.

  • Blood Volume Determination in obese and normal-weight gravidas: the hydroxyethyl starch method.
    American Journal of Obstetrics and Gynecology, 2015
    Co-Authors: Laura K Vricella, Judette Louis, Edward K. Chien, Brian M Mercer
    Abstract:

    Objective The impact of obesity on maternal Blood Volume in pregnancy has not been reported. We compared the Blood Volumes of obese and normal-weight gravidas using a validated hydroxyethyl starch (HES) dilution technique for Blood Volume estimation. Study Design Blood Volumes were estimated in 30 normal-weight (pregravid body mass index [BMI] 2 ) and 30 obese (pregravid BMI >35 kg/m 2 ) gravidas >34 weeks' gestation using a modified HES dilution technique. Blood samples obtained before and 10 minutes after HES injection were analyzed for plasma glucose concentrations after acid hydrolysis of HES. Blood Volume was calculated from the difference between glucose concentrations measured in hydrolyzed plasma. Results Obese gravidas had higher pregravid and visit BMI (mean [SD]): pregravid (41 [4] vs 22 [2] kg/m 2 , P  = .001); visit (42 [4] vs 27 [2] kg/m 2 , P  = .001), but lower weight gain (5 [7] vs 12 [4] kg, P  = .001) than normal-weight women. Obese gravidas had similar estimated total Blood Volume to normal-weight women (8103 ± 2452 vs 6944 ± 2830 mL, P  = .1), but lower Blood Volume per kilogram weight (73 ± 22 vs 95 ± 30 mL/kg, P  = .007). Conclusion Obese gravidas have similar circulating Blood Volume, but lower Blood Volume per kilogram body weight, than normal-weight gravidas near term.

Laura K Vricella - One of the best experts on this subject based on the ideXlab platform.

  • Blood Volume Determination in obese and normal-weight gravidas: the hydroxyethyl starch method.
    American journal of obstetrics and gynecology, 2015
    Co-Authors: Laura K Vricella, Judette M Louis, Edward Chien, Brian M Mercer
    Abstract:

    The impact of obesity on maternal Blood Volume in pregnancy has not been reported. We compared the Blood Volumes of obese and normal-weight gravidas using a validated hydroxyethyl starch (HES) dilution technique for Blood Volume estimation. Blood Volumes were estimated in 30 normal-weight (pregravid body mass index [BMI] <25 kg/m(2)) and 30 obese (pregravid BMI >35 kg/m(2)) gravidas >34 weeks' gestation using a modified HES dilution technique. Blood samples obtained before and 10 minutes after HES injection were analyzed for plasma glucose concentrations after acid hydrolysis of HES. Blood Volume was calculated from the difference between glucose concentrations measured in hydrolyzed plasma. Obese gravidas had higher pregravid and visit BMI (mean [SD]): pregravid (41 [4] vs 22 [2] kg/m(2), P = .001); visit (42 [4] vs 27 [2] kg/m(2), P = .001), but lower weight gain (5 [7] vs 12 [4] kg, P = .001) than normal-weight women. Obese gravidas had similar estimated total Blood Volume to normal-weight women (8103 ± 2452 vs 6944 ± 2830 mL, P = .1), but lower Blood Volume per kilogram weight (73 ± 22 vs 95 ± 30 mL/kg, P = .007). Obese gravidas have similar circulating Blood Volume, but lower Blood Volume per kilogram body weight, than normal-weight gravidas near term. Copyright © 2015 Elsevier Inc. All rights reserved.

  • Blood Volume Determination in obese and normal-weight gravidas: the hydroxyethyl starch method.
    American Journal of Obstetrics and Gynecology, 2015
    Co-Authors: Laura K Vricella, Judette Louis, Edward K. Chien, Brian M Mercer
    Abstract:

    Objective The impact of obesity on maternal Blood Volume in pregnancy has not been reported. We compared the Blood Volumes of obese and normal-weight gravidas using a validated hydroxyethyl starch (HES) dilution technique for Blood Volume estimation. Study Design Blood Volumes were estimated in 30 normal-weight (pregravid body mass index [BMI] 2 ) and 30 obese (pregravid BMI >35 kg/m 2 ) gravidas >34 weeks' gestation using a modified HES dilution technique. Blood samples obtained before and 10 minutes after HES injection were analyzed for plasma glucose concentrations after acid hydrolysis of HES. Blood Volume was calculated from the difference between glucose concentrations measured in hydrolyzed plasma. Results Obese gravidas had higher pregravid and visit BMI (mean [SD]): pregravid (41 [4] vs 22 [2] kg/m 2 , P  = .001); visit (42 [4] vs 27 [2] kg/m 2 , P  = .001), but lower weight gain (5 [7] vs 12 [4] kg, P  = .001) than normal-weight women. Obese gravidas had similar estimated total Blood Volume to normal-weight women (8103 ± 2452 vs 6944 ± 2830 mL, P  = .1), but lower Blood Volume per kilogram weight (73 ± 22 vs 95 ± 30 mL/kg, P  = .007). Conclusion Obese gravidas have similar circulating Blood Volume, but lower Blood Volume per kilogram body weight, than normal-weight gravidas near term.

Edward K. Chien - One of the best experts on this subject based on the ideXlab platform.

  • Blood Volume Determination in obese and normal-weight gravidas: the hydroxyethyl starch method.
    American Journal of Obstetrics and Gynecology, 2015
    Co-Authors: Laura K Vricella, Judette Louis, Edward K. Chien, Brian M Mercer
    Abstract:

    Objective The impact of obesity on maternal Blood Volume in pregnancy has not been reported. We compared the Blood Volumes of obese and normal-weight gravidas using a validated hydroxyethyl starch (HES) dilution technique for Blood Volume estimation. Study Design Blood Volumes were estimated in 30 normal-weight (pregravid body mass index [BMI] 2 ) and 30 obese (pregravid BMI >35 kg/m 2 ) gravidas >34 weeks' gestation using a modified HES dilution technique. Blood samples obtained before and 10 minutes after HES injection were analyzed for plasma glucose concentrations after acid hydrolysis of HES. Blood Volume was calculated from the difference between glucose concentrations measured in hydrolyzed plasma. Results Obese gravidas had higher pregravid and visit BMI (mean [SD]): pregravid (41 [4] vs 22 [2] kg/m 2 , P  = .001); visit (42 [4] vs 27 [2] kg/m 2 , P  = .001), but lower weight gain (5 [7] vs 12 [4] kg, P  = .001) than normal-weight women. Obese gravidas had similar estimated total Blood Volume to normal-weight women (8103 ± 2452 vs 6944 ± 2830 mL, P  = .1), but lower Blood Volume per kilogram weight (73 ± 22 vs 95 ± 30 mL/kg, P  = .007). Conclusion Obese gravidas have similar circulating Blood Volume, but lower Blood Volume per kilogram body weight, than normal-weight gravidas near term.

Judette Louis - One of the best experts on this subject based on the ideXlab platform.

  • Blood Volume Determination in obese and normal-weight gravidas: the hydroxyethyl starch method.
    American Journal of Obstetrics and Gynecology, 2015
    Co-Authors: Laura K Vricella, Judette Louis, Edward K. Chien, Brian M Mercer
    Abstract:

    Objective The impact of obesity on maternal Blood Volume in pregnancy has not been reported. We compared the Blood Volumes of obese and normal-weight gravidas using a validated hydroxyethyl starch (HES) dilution technique for Blood Volume estimation. Study Design Blood Volumes were estimated in 30 normal-weight (pregravid body mass index [BMI] 2 ) and 30 obese (pregravid BMI >35 kg/m 2 ) gravidas >34 weeks' gestation using a modified HES dilution technique. Blood samples obtained before and 10 minutes after HES injection were analyzed for plasma glucose concentrations after acid hydrolysis of HES. Blood Volume was calculated from the difference between glucose concentrations measured in hydrolyzed plasma. Results Obese gravidas had higher pregravid and visit BMI (mean [SD]): pregravid (41 [4] vs 22 [2] kg/m 2 , P  = .001); visit (42 [4] vs 27 [2] kg/m 2 , P  = .001), but lower weight gain (5 [7] vs 12 [4] kg, P  = .001) than normal-weight women. Obese gravidas had similar estimated total Blood Volume to normal-weight women (8103 ± 2452 vs 6944 ± 2830 mL, P  = .1), but lower Blood Volume per kilogram weight (73 ± 22 vs 95 ± 30 mL/kg, P  = .007). Conclusion Obese gravidas have similar circulating Blood Volume, but lower Blood Volume per kilogram body weight, than normal-weight gravidas near term.

Edward Chien - One of the best experts on this subject based on the ideXlab platform.

  • Blood Volume Determination in obese and normal-weight gravidas: the hydroxyethyl starch method.
    American journal of obstetrics and gynecology, 2015
    Co-Authors: Laura K Vricella, Judette M Louis, Edward Chien, Brian M Mercer
    Abstract:

    The impact of obesity on maternal Blood Volume in pregnancy has not been reported. We compared the Blood Volumes of obese and normal-weight gravidas using a validated hydroxyethyl starch (HES) dilution technique for Blood Volume estimation. Blood Volumes were estimated in 30 normal-weight (pregravid body mass index [BMI] <25 kg/m(2)) and 30 obese (pregravid BMI >35 kg/m(2)) gravidas >34 weeks' gestation using a modified HES dilution technique. Blood samples obtained before and 10 minutes after HES injection were analyzed for plasma glucose concentrations after acid hydrolysis of HES. Blood Volume was calculated from the difference between glucose concentrations measured in hydrolyzed plasma. Obese gravidas had higher pregravid and visit BMI (mean [SD]): pregravid (41 [4] vs 22 [2] kg/m(2), P = .001); visit (42 [4] vs 27 [2] kg/m(2), P = .001), but lower weight gain (5 [7] vs 12 [4] kg, P = .001) than normal-weight women. Obese gravidas had similar estimated total Blood Volume to normal-weight women (8103 ± 2452 vs 6944 ± 2830 mL, P = .1), but lower Blood Volume per kilogram weight (73 ± 22 vs 95 ± 30 mL/kg, P = .007). Obese gravidas have similar circulating Blood Volume, but lower Blood Volume per kilogram body weight, than normal-weight gravidas near term. Copyright © 2015 Elsevier Inc. All rights reserved.