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Fabio Pitta - One of the best experts on this subject based on the ideXlab platform.

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity). Methods Thirty-eight subjects with COPD (21 men, 66 ± 8 years, forced expiratory volume in the first second (FEV_1) 42 ± 16 % predicted) underwent assessments of SNIP, airflow limitation, body mass Index (BMI), dyspnea (Medical Research Council scale), and exercise capacity (6-min walking test, 6MWT). The BODE Index was calculated, and patients were separated into two groups according to the BODE quartiles (1 and 2, or 3 and 4). Results Patients from quartiles 3 and 4 presented lower values of SNIP than patients from quartiles 1 and 2 (73 ± 18 vs 56 ± 21 cmH_2O, respectively; p  = 0.01). There was significant and inverse correlation between SNIP and the BODE Index ( r  = −0.62; p

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity).

  • Relationship between sniff nasal inspiratory pressure and the multidimensional BODE Index in patients with COPD
    European Respiratory Journal, 2013
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Mônica Yosino, Fabio Pitta
    Abstract:

    Introduction : Inspiratory muscle force has been traditionally assessed by maximal inspiratory pressure (MIP). The sniff nasal inspiratory pressure (SNIP) is an alternative to the MIP and is considered as predictor of mortality in patients with chronic obstructive pulmonary disease (COPD). However, the relationship of SNIP with multidimensional Indexes which predict mortality in COPD patients such as the Body mass Index, airflow Obstruction, Dyspnea and Exercise capacity (BODE) has not yet been investigated. Objective: To investigate the relationship between SNIP and BODE Index in COPD patients COPD. Methods : Thirty-eight subjects with COPD (21 men, 66±8 years, FEV 1 42±16% of predicted) underwent assessments: SNIP, spirometry, degree of dyspnea (Medical Research Council scale) and 6-minute walk test. The BODE Index was calculated and the patients were divided into four quartiles according to the BODE score. Results : There was significant difference in the SNIP (cmH 2 O and %predicted) when patients in the different BODE quartiles were compared. The SNIP (cmH 2 O and %predicted) showed moderate correlation with the BODE and the updated BODE (-0.45 2 O (OR: 4.67, 95% CI 1.19 to 18.35, P= 0.03). Conclusion : SNIP is moderately and significantly related with the BODE Index in COPD patients. Moreover, the cutoff point of 63 cmH 2 O showed the best combination of sensitivity and specificity for predicting a higher ( i.e ., worse) score in the BODE Index.

  • does the BODE Index reflect the level of physical activity in daily life in patients with copd
    Revista Brasileira De Fisioterapia, 2011
    Co-Authors: Leandro C Mantoani, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Monica Martins Guimaraes, Renato Vitorasso, Fabio Pitta
    Abstract:

    OBJECTIVES: To study the relationship between the level of physical activity in daily life and disease severity assessed by the BODE Index in patients with chronic obstructive pulmonary disease (COPD). METHODS: Sixty-seven patients with COPD (36 men) with forced expiratory volume in the first second (FEV1) of 39 (27-47)% predicted and age of 66 (61-72) years old were evaluated by spirometry, dyspnea levels (measured by the Medical Research Council scale, MRC) and by the 6-minute walking test (6MWT). The BODE Index was calculated based on the body mass Index (weight/height2), FEV1, MRC and 6MWT, and then the patients were divided in four quartiles according to their scores (Quartile I: 0 to 2 points, n=15; Quartile II: 3 to 4 points, n=20; Quartile III: 5 to 6 points, n=23; Quartile IV: 7 to 10 points, n=9). Two activity monitors (DynaPort® and SenseWear®) were used to evaluate the level of physical activity in daily life. The Kruskal-Wallis test (Dunns's post-hoc test), the Mann-Whitney test and the Spearman Correlation Coefficient were used for statistical analysis. RESULTS: There were modest correlation between the BODE Index and the time spent walking per day, the total daily energy expenditure and the time spent in moderate and vigorous activities per day (-0.32 < r <- 0.47; p<0.01 for all variables). When comparing the pooled quartiles I+II with III+IV, there were significant difference between the time spent walking per day, the total daily energy expenditure and the time spent in moderate activities per day (p<0.05). CONCLUSION: The level of physical activity in daily life has a modest correlation with the classification of COPD severity assessed by the BODE Index, reflecting only differences between patients with classified as mild-moderate and severe-very severe COPD.

  • Does the BODE Index reflect the level of physical activity in daily life in patients with COPD
    Revista brasileira de fisioterapia (Sao Carlos (Sao Paulo Brazil)), 2011
    Co-Authors: Leandro C Mantoani, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Monica Martins Guimaraes, Renato Vitorasso, Fabio Pitta
    Abstract:

    OBJECTIVES: To study the relationship between the level of physical activity in daily life and disease severity assessed by the BODE Index in patients with chronic obstructive pulmonary disease (COPD). METHODS: Sixty-seven patients with COPD (36 men) with forced expiratory volume in the first second (FEV1) of 39 (27-47)% predicted and age of 66 (61-72) years old were evaluated by spirometry, dyspnea levels (measured by the Medical Research Council scale, MRC) and by the 6-minute walking test (6MWT). The BODE Index was calculated based on the body mass Index (weight/height2), FEV1, MRC and 6MWT, and then the patients were divided in four quartiles according to their scores (Quartile I: 0 to 2 points, n=15; Quartile II: 3 to 4 points, n=20; Quartile III: 5 to 6 points, n=23; Quartile IV: 7 to 10 points, n=9). Two activity monitors (DynaPort® and SenseWear®) were used to evaluate the level of physical activity in daily life. The Kruskal-Wallis test (Dunns's post-hoc test), the Mann-Whitney test and the Spearman Correlation Coefficient were used for statistical analysis. RESULTS: There were modest correlation between the BODE Index and the time spent walking per day, the total daily energy expenditure and the time spent in moderate and vigorous activities per day (-0.32 < r

Leila Donária - One of the best experts on this subject based on the ideXlab platform.

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity). Methods Thirty-eight subjects with COPD (21 men, 66 ± 8 years, forced expiratory volume in the first second (FEV_1) 42 ± 16 % predicted) underwent assessments of SNIP, airflow limitation, body mass Index (BMI), dyspnea (Medical Research Council scale), and exercise capacity (6-min walking test, 6MWT). The BODE Index was calculated, and patients were separated into two groups according to the BODE quartiles (1 and 2, or 3 and 4). Results Patients from quartiles 3 and 4 presented lower values of SNIP than patients from quartiles 1 and 2 (73 ± 18 vs 56 ± 21 cmH_2O, respectively; p  = 0.01). There was significant and inverse correlation between SNIP and the BODE Index ( r  = −0.62; p

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity).

  • Relationship between sniff nasal inspiratory pressure and the multidimensional BODE Index in patients with COPD
    European Respiratory Journal, 2013
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Mônica Yosino, Fabio Pitta
    Abstract:

    Introduction : Inspiratory muscle force has been traditionally assessed by maximal inspiratory pressure (MIP). The sniff nasal inspiratory pressure (SNIP) is an alternative to the MIP and is considered as predictor of mortality in patients with chronic obstructive pulmonary disease (COPD). However, the relationship of SNIP with multidimensional Indexes which predict mortality in COPD patients such as the Body mass Index, airflow Obstruction, Dyspnea and Exercise capacity (BODE) has not yet been investigated. Objective: To investigate the relationship between SNIP and BODE Index in COPD patients COPD. Methods : Thirty-eight subjects with COPD (21 men, 66±8 years, FEV 1 42±16% of predicted) underwent assessments: SNIP, spirometry, degree of dyspnea (Medical Research Council scale) and 6-minute walk test. The BODE Index was calculated and the patients were divided into four quartiles according to the BODE score. Results : There was significant difference in the SNIP (cmH 2 O and %predicted) when patients in the different BODE quartiles were compared. The SNIP (cmH 2 O and %predicted) showed moderate correlation with the BODE and the updated BODE (-0.45 2 O (OR: 4.67, 95% CI 1.19 to 18.35, P= 0.03). Conclusion : SNIP is moderately and significantly related with the BODE Index in COPD patients. Moreover, the cutoff point of 63 cmH 2 O showed the best combination of sensitivity and specificity for predicting a higher ( i.e ., worse) score in the BODE Index.

Vanessa Suziane Probst - One of the best experts on this subject based on the ideXlab platform.

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity). Methods Thirty-eight subjects with COPD (21 men, 66 ± 8 years, forced expiratory volume in the first second (FEV_1) 42 ± 16 % predicted) underwent assessments of SNIP, airflow limitation, body mass Index (BMI), dyspnea (Medical Research Council scale), and exercise capacity (6-min walking test, 6MWT). The BODE Index was calculated, and patients were separated into two groups according to the BODE quartiles (1 and 2, or 3 and 4). Results Patients from quartiles 3 and 4 presented lower values of SNIP than patients from quartiles 1 and 2 (73 ± 18 vs 56 ± 21 cmH_2O, respectively; p  = 0.01). There was significant and inverse correlation between SNIP and the BODE Index ( r  = −0.62; p

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity).

  • Relationship between sniff nasal inspiratory pressure and the multidimensional BODE Index in patients with COPD
    European Respiratory Journal, 2013
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Mônica Yosino, Fabio Pitta
    Abstract:

    Introduction : Inspiratory muscle force has been traditionally assessed by maximal inspiratory pressure (MIP). The sniff nasal inspiratory pressure (SNIP) is an alternative to the MIP and is considered as predictor of mortality in patients with chronic obstructive pulmonary disease (COPD). However, the relationship of SNIP with multidimensional Indexes which predict mortality in COPD patients such as the Body mass Index, airflow Obstruction, Dyspnea and Exercise capacity (BODE) has not yet been investigated. Objective: To investigate the relationship between SNIP and BODE Index in COPD patients COPD. Methods : Thirty-eight subjects with COPD (21 men, 66±8 years, FEV 1 42±16% of predicted) underwent assessments: SNIP, spirometry, degree of dyspnea (Medical Research Council scale) and 6-minute walk test. The BODE Index was calculated and the patients were divided into four quartiles according to the BODE score. Results : There was significant difference in the SNIP (cmH 2 O and %predicted) when patients in the different BODE quartiles were compared. The SNIP (cmH 2 O and %predicted) showed moderate correlation with the BODE and the updated BODE (-0.45 2 O (OR: 4.67, 95% CI 1.19 to 18.35, P= 0.03). Conclusion : SNIP is moderately and significantly related with the BODE Index in COPD patients. Moreover, the cutoff point of 63 cmH 2 O showed the best combination of sensitivity and specificity for predicting a higher ( i.e ., worse) score in the BODE Index.

  • does the BODE Index reflect the level of physical activity in daily life in patients with copd
    Revista Brasileira De Fisioterapia, 2011
    Co-Authors: Leandro C Mantoani, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Monica Martins Guimaraes, Renato Vitorasso, Fabio Pitta
    Abstract:

    OBJECTIVES: To study the relationship between the level of physical activity in daily life and disease severity assessed by the BODE Index in patients with chronic obstructive pulmonary disease (COPD). METHODS: Sixty-seven patients with COPD (36 men) with forced expiratory volume in the first second (FEV1) of 39 (27-47)% predicted and age of 66 (61-72) years old were evaluated by spirometry, dyspnea levels (measured by the Medical Research Council scale, MRC) and by the 6-minute walking test (6MWT). The BODE Index was calculated based on the body mass Index (weight/height2), FEV1, MRC and 6MWT, and then the patients were divided in four quartiles according to their scores (Quartile I: 0 to 2 points, n=15; Quartile II: 3 to 4 points, n=20; Quartile III: 5 to 6 points, n=23; Quartile IV: 7 to 10 points, n=9). Two activity monitors (DynaPort® and SenseWear®) were used to evaluate the level of physical activity in daily life. The Kruskal-Wallis test (Dunns's post-hoc test), the Mann-Whitney test and the Spearman Correlation Coefficient were used for statistical analysis. RESULTS: There were modest correlation between the BODE Index and the time spent walking per day, the total daily energy expenditure and the time spent in moderate and vigorous activities per day (-0.32 < r <- 0.47; p<0.01 for all variables). When comparing the pooled quartiles I+II with III+IV, there were significant difference between the time spent walking per day, the total daily energy expenditure and the time spent in moderate activities per day (p<0.05). CONCLUSION: The level of physical activity in daily life has a modest correlation with the classification of COPD severity assessed by the BODE Index, reflecting only differences between patients with classified as mild-moderate and severe-very severe COPD.

  • Does the BODE Index reflect the level of physical activity in daily life in patients with COPD
    Revista brasileira de fisioterapia (Sao Carlos (Sao Paulo Brazil)), 2011
    Co-Authors: Leandro C Mantoani, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Monica Martins Guimaraes, Renato Vitorasso, Fabio Pitta
    Abstract:

    OBJECTIVES: To study the relationship between the level of physical activity in daily life and disease severity assessed by the BODE Index in patients with chronic obstructive pulmonary disease (COPD). METHODS: Sixty-seven patients with COPD (36 men) with forced expiratory volume in the first second (FEV1) of 39 (27-47)% predicted and age of 66 (61-72) years old were evaluated by spirometry, dyspnea levels (measured by the Medical Research Council scale, MRC) and by the 6-minute walking test (6MWT). The BODE Index was calculated based on the body mass Index (weight/height2), FEV1, MRC and 6MWT, and then the patients were divided in four quartiles according to their scores (Quartile I: 0 to 2 points, n=15; Quartile II: 3 to 4 points, n=20; Quartile III: 5 to 6 points, n=23; Quartile IV: 7 to 10 points, n=9). Two activity monitors (DynaPort® and SenseWear®) were used to evaluate the level of physical activity in daily life. The Kruskal-Wallis test (Dunns's post-hoc test), the Mann-Whitney test and the Spearman Correlation Coefficient were used for statistical analysis. RESULTS: There were modest correlation between the BODE Index and the time spent walking per day, the total daily energy expenditure and the time spent in moderate and vigorous activities per day (-0.32 < r

Nidia Aparecida Hernandes - One of the best experts on this subject based on the ideXlab platform.

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity). Methods Thirty-eight subjects with COPD (21 men, 66 ± 8 years, forced expiratory volume in the first second (FEV_1) 42 ± 16 % predicted) underwent assessments of SNIP, airflow limitation, body mass Index (BMI), dyspnea (Medical Research Council scale), and exercise capacity (6-min walking test, 6MWT). The BODE Index was calculated, and patients were separated into two groups according to the BODE quartiles (1 and 2, or 3 and 4). Results Patients from quartiles 3 and 4 presented lower values of SNIP than patients from quartiles 1 and 2 (73 ± 18 vs 56 ± 21 cmH_2O, respectively; p  = 0.01). There was significant and inverse correlation between SNIP and the BODE Index ( r  = −0.62; p

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity).

  • Relationship between sniff nasal inspiratory pressure and the multidimensional BODE Index in patients with COPD
    European Respiratory Journal, 2013
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Mônica Yosino, Fabio Pitta
    Abstract:

    Introduction : Inspiratory muscle force has been traditionally assessed by maximal inspiratory pressure (MIP). The sniff nasal inspiratory pressure (SNIP) is an alternative to the MIP and is considered as predictor of mortality in patients with chronic obstructive pulmonary disease (COPD). However, the relationship of SNIP with multidimensional Indexes which predict mortality in COPD patients such as the Body mass Index, airflow Obstruction, Dyspnea and Exercise capacity (BODE) has not yet been investigated. Objective: To investigate the relationship between SNIP and BODE Index in COPD patients COPD. Methods : Thirty-eight subjects with COPD (21 men, 66±8 years, FEV 1 42±16% of predicted) underwent assessments: SNIP, spirometry, degree of dyspnea (Medical Research Council scale) and 6-minute walk test. The BODE Index was calculated and the patients were divided into four quartiles according to the BODE score. Results : There was significant difference in the SNIP (cmH 2 O and %predicted) when patients in the different BODE quartiles were compared. The SNIP (cmH 2 O and %predicted) showed moderate correlation with the BODE and the updated BODE (-0.45 2 O (OR: 4.67, 95% CI 1.19 to 18.35, P= 0.03). Conclusion : SNIP is moderately and significantly related with the BODE Index in COPD patients. Moreover, the cutoff point of 63 cmH 2 O showed the best combination of sensitivity and specificity for predicting a higher ( i.e ., worse) score in the BODE Index.

  • does the BODE Index reflect the level of physical activity in daily life in patients with copd
    Revista Brasileira De Fisioterapia, 2011
    Co-Authors: Leandro C Mantoani, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Monica Martins Guimaraes, Renato Vitorasso, Fabio Pitta
    Abstract:

    OBJECTIVES: To study the relationship between the level of physical activity in daily life and disease severity assessed by the BODE Index in patients with chronic obstructive pulmonary disease (COPD). METHODS: Sixty-seven patients with COPD (36 men) with forced expiratory volume in the first second (FEV1) of 39 (27-47)% predicted and age of 66 (61-72) years old were evaluated by spirometry, dyspnea levels (measured by the Medical Research Council scale, MRC) and by the 6-minute walking test (6MWT). The BODE Index was calculated based on the body mass Index (weight/height2), FEV1, MRC and 6MWT, and then the patients were divided in four quartiles according to their scores (Quartile I: 0 to 2 points, n=15; Quartile II: 3 to 4 points, n=20; Quartile III: 5 to 6 points, n=23; Quartile IV: 7 to 10 points, n=9). Two activity monitors (DynaPort® and SenseWear®) were used to evaluate the level of physical activity in daily life. The Kruskal-Wallis test (Dunns's post-hoc test), the Mann-Whitney test and the Spearman Correlation Coefficient were used for statistical analysis. RESULTS: There were modest correlation between the BODE Index and the time spent walking per day, the total daily energy expenditure and the time spent in moderate and vigorous activities per day (-0.32 < r <- 0.47; p<0.01 for all variables). When comparing the pooled quartiles I+II with III+IV, there were significant difference between the time spent walking per day, the total daily energy expenditure and the time spent in moderate activities per day (p<0.05). CONCLUSION: The level of physical activity in daily life has a modest correlation with the classification of COPD severity assessed by the BODE Index, reflecting only differences between patients with classified as mild-moderate and severe-very severe COPD.

  • Does the BODE Index reflect the level of physical activity in daily life in patients with COPD
    Revista brasileira de fisioterapia (Sao Carlos (Sao Paulo Brazil)), 2011
    Co-Authors: Leandro C Mantoani, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Monica Martins Guimaraes, Renato Vitorasso, Fabio Pitta
    Abstract:

    OBJECTIVES: To study the relationship between the level of physical activity in daily life and disease severity assessed by the BODE Index in patients with chronic obstructive pulmonary disease (COPD). METHODS: Sixty-seven patients with COPD (36 men) with forced expiratory volume in the first second (FEV1) of 39 (27-47)% predicted and age of 66 (61-72) years old were evaluated by spirometry, dyspnea levels (measured by the Medical Research Council scale, MRC) and by the 6-minute walking test (6MWT). The BODE Index was calculated based on the body mass Index (weight/height2), FEV1, MRC and 6MWT, and then the patients were divided in four quartiles according to their scores (Quartile I: 0 to 2 points, n=15; Quartile II: 3 to 4 points, n=20; Quartile III: 5 to 6 points, n=23; Quartile IV: 7 to 10 points, n=9). Two activity monitors (DynaPort® and SenseWear®) were used to evaluate the level of physical activity in daily life. The Kruskal-Wallis test (Dunns's post-hoc test), the Mann-Whitney test and the Spearman Correlation Coefficient were used for statistical analysis. RESULTS: There were modest correlation between the BODE Index and the time spent walking per day, the total daily energy expenditure and the time spent in moderate and vigorous activities per day (-0.32 < r

Rafael Mesquita - One of the best experts on this subject based on the ideXlab platform.

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity). Methods Thirty-eight subjects with COPD (21 men, 66 ± 8 years, forced expiratory volume in the first second (FEV_1) 42 ± 16 % predicted) underwent assessments of SNIP, airflow limitation, body mass Index (BMI), dyspnea (Medical Research Council scale), and exercise capacity (6-min walking test, 6MWT). The BODE Index was calculated, and patients were separated into two groups according to the BODE quartiles (1 and 2, or 3 and 4). Results Patients from quartiles 3 and 4 presented lower values of SNIP than patients from quartiles 1 and 2 (73 ± 18 vs 56 ± 21 cmH_2O, respectively; p  = 0.01). There was significant and inverse correlation between SNIP and the BODE Index ( r  = −0.62; p

  • Relationship Between Sniff Nasal Inspiratory Pressure and BODE Index in Patients with COPD
    Lung, 2014
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Luciana Sípoli, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Fabio Pitta
    Abstract:

    Purpose The aims of this study were to investigate the relationship between sniff nasal inspiratory pressure (SNIP) and severity of chronic obstructive pulmonary disease (COPD) as defined by the BODE Index, and to investigate the capacity of different SNIP cutoffs to predict a BODE Index score ≥5 (i.e., worse disease severity).

  • Relationship between sniff nasal inspiratory pressure and the multidimensional BODE Index in patients with COPD
    European Respiratory Journal, 2013
    Co-Authors: Leila Donária, Rafael Mesquita, Larissa Martinez, Josiane Marques Felcar, Vanessa Suziane Probst, Nidia Aparecida Hernandes, Mônica Yosino, Fabio Pitta
    Abstract:

    Introduction : Inspiratory muscle force has been traditionally assessed by maximal inspiratory pressure (MIP). The sniff nasal inspiratory pressure (SNIP) is an alternative to the MIP and is considered as predictor of mortality in patients with chronic obstructive pulmonary disease (COPD). However, the relationship of SNIP with multidimensional Indexes which predict mortality in COPD patients such as the Body mass Index, airflow Obstruction, Dyspnea and Exercise capacity (BODE) has not yet been investigated. Objective: To investigate the relationship between SNIP and BODE Index in COPD patients COPD. Methods : Thirty-eight subjects with COPD (21 men, 66±8 years, FEV 1 42±16% of predicted) underwent assessments: SNIP, spirometry, degree of dyspnea (Medical Research Council scale) and 6-minute walk test. The BODE Index was calculated and the patients were divided into four quartiles according to the BODE score. Results : There was significant difference in the SNIP (cmH 2 O and %predicted) when patients in the different BODE quartiles were compared. The SNIP (cmH 2 O and %predicted) showed moderate correlation with the BODE and the updated BODE (-0.45 2 O (OR: 4.67, 95% CI 1.19 to 18.35, P= 0.03). Conclusion : SNIP is moderately and significantly related with the BODE Index in COPD patients. Moreover, the cutoff point of 63 cmH 2 O showed the best combination of sensitivity and specificity for predicting a higher ( i.e ., worse) score in the BODE Index.