The Experts below are selected from a list of 126 Experts worldwide ranked by ideXlab platform
Hajime Yamabayashi - One of the best experts on this subject based on the ideXlab platform.
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Functional Residual Capacity and Airway Resistance of the Rat Measured with a Heat- and Temperature-Adjusted Body Plethysmograph
The journal of physiological sciences : JPS, 2006Co-Authors: Sakurako Tajiri, Tetsuri Kondo, Hajime YamabayashiAbstract:The functional residual capacity (FRC) and airway resistance (R(aw)) of the rat were measured, using a newly designed Body Plethysmograph (BPG), the inner environment of which was maintained at Body temperature and was water-vapor saturated. The subjects were anesthetized and tracheally intubated male Wistar rats (n = 15). After measuring the FRC and R(aw), we analyzed the effects of inhaled methacholine (Mch, 0-8 mg/ml) on R(aw).The determined FRC was 5.37 +/- 0.22 ml (mean +/- SE). An almost linear relationship between box pressure and respiratory flow was obtained when the difference between box-gas temperature and the rectal temperature of the rat was less than 1.0 degrees C. The R(aw) at FRC was 0.230 +/- 0.017 cm H(2)O/ml/s. It increased proportionally with increases in the Mch concentration. When the dynamic changes in R(aw) were analyzed, the R(aw) was found to progressively increase during expiration; this increase continued throughout inspiration. Thus in the rat, R(aw) is not simply a function of changes in lung volume. In conclusion, the humidity- and temperature-adjusted BPG provided an absolute and possibly dynamic value of R(aw).
Leonhard Reindl - One of the best experts on this subject based on the ideXlab platform.
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An alternative way to measure total lung capacity: a pilot study
Current Directions in Biomedical Engineering, 2020Co-Authors: Bernhard Laufer, Sabine Krueger-ziolek, Knut Moeller, Paul D. Docherty, Fabian Hoeflinger, Leonhard ReindlAbstract:AbstractTotal lung capacity is usually measured by a Body Plethysmograph or helium dilution methods. In this study an alternative approach to obtain total lung capacity of spontaneous breathing subjects is introduced. The device utilises an optoelectronic Plethysmograph and a small tube, which measures mouth pressure and allows total lung capacity to be obtained, which differs less than 0.4 L from the total lung capacity of the Body Plethysmograph. The method shows potential to be a less burdensome method to estimate total lung capacity determination than the Body Plethysmograph.
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EMBC - Tidal volume via circumferences of the upper Body: a pilot study
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Inte, 2019Co-Authors: Bernhard Laufer, Sabine Krueger-ziolek, Paul D. Docherty, Fabian Hoeflinger, Leonhard Reindl, Knut MoellerAbstract:The gold standard for tidal volume measurement is spirometry. Based on retrospective data, this study evaluates different geometric lung models in their ability to deliver accurate tidal volumes from changes in thoracic and abdominal circumference. The geometric lung models showed good coefficients of determination (adjusted R2 >0.97) compared to the tidal volumes measured by a Body Plethysmograph. Tidal volumes obtained by circumference changes might be used in surveillance systems to analyze respiration without a face mask.
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Hierarchical Analysis of Thorax Models to Measure Tidal Volume
Current Directions in Biomedical Engineering, 2018Co-Authors: Bernhard Laufer, Sabine Krueger-ziolek, Knut Moeller, Paul D. Docherty, Fabian Hoeflinger, Leonhard ReindlAbstract:AbstractMotion tracking of thorax kinematics can be used to determine respiration. However, determining a minimal sensor configuration from 64 candidate sensor locations is associated with high computational costs. Hence, a hierarchical optimization method was proposed to determine the optimal combination of sensors. The hierarchical method was assessed by its ability to quickly determine the sensor combination that will yield optimal modelled tidal volume compared to Body Plethysmograph measurements. This method was able to find the optimal sensor combinations, in approximately 2% of the estimated time required by an exhaustive search.
Sakurako Tajiri - One of the best experts on this subject based on the ideXlab platform.
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Functional Residual Capacity and Airway Resistance of the Rat Measured with a Heat- and Temperature-Adjusted Body Plethysmograph
The journal of physiological sciences : JPS, 2006Co-Authors: Sakurako Tajiri, Tetsuri Kondo, Hajime YamabayashiAbstract:The functional residual capacity (FRC) and airway resistance (R(aw)) of the rat were measured, using a newly designed Body Plethysmograph (BPG), the inner environment of which was maintained at Body temperature and was water-vapor saturated. The subjects were anesthetized and tracheally intubated male Wistar rats (n = 15). After measuring the FRC and R(aw), we analyzed the effects of inhaled methacholine (Mch, 0-8 mg/ml) on R(aw).The determined FRC was 5.37 +/- 0.22 ml (mean +/- SE). An almost linear relationship between box pressure and respiratory flow was obtained when the difference between box-gas temperature and the rectal temperature of the rat was less than 1.0 degrees C. The R(aw) at FRC was 0.230 +/- 0.017 cm H(2)O/ml/s. It increased proportionally with increases in the Mch concentration. When the dynamic changes in R(aw) were analyzed, the R(aw) was found to progressively increase during expiration; this increase continued throughout inspiration. Thus in the rat, R(aw) is not simply a function of changes in lung volume. In conclusion, the humidity- and temperature-adjusted BPG provided an absolute and possibly dynamic value of R(aw).
Bernhard Laufer - One of the best experts on this subject based on the ideXlab platform.
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An alternative way to measure total lung capacity: a pilot study
Current Directions in Biomedical Engineering, 2020Co-Authors: Bernhard Laufer, Sabine Krueger-ziolek, Knut Moeller, Paul D. Docherty, Fabian Hoeflinger, Leonhard ReindlAbstract:AbstractTotal lung capacity is usually measured by a Body Plethysmograph or helium dilution methods. In this study an alternative approach to obtain total lung capacity of spontaneous breathing subjects is introduced. The device utilises an optoelectronic Plethysmograph and a small tube, which measures mouth pressure and allows total lung capacity to be obtained, which differs less than 0.4 L from the total lung capacity of the Body Plethysmograph. The method shows potential to be a less burdensome method to estimate total lung capacity determination than the Body Plethysmograph.
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EMBC - Tidal volume via circumferences of the upper Body: a pilot study
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Inte, 2019Co-Authors: Bernhard Laufer, Sabine Krueger-ziolek, Paul D. Docherty, Fabian Hoeflinger, Leonhard Reindl, Knut MoellerAbstract:The gold standard for tidal volume measurement is spirometry. Based on retrospective data, this study evaluates different geometric lung models in their ability to deliver accurate tidal volumes from changes in thoracic and abdominal circumference. The geometric lung models showed good coefficients of determination (adjusted R2 >0.97) compared to the tidal volumes measured by a Body Plethysmograph. Tidal volumes obtained by circumference changes might be used in surveillance systems to analyze respiration without a face mask.
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Hierarchical Analysis of Thorax Models to Measure Tidal Volume
Current Directions in Biomedical Engineering, 2018Co-Authors: Bernhard Laufer, Sabine Krueger-ziolek, Knut Moeller, Paul D. Docherty, Fabian Hoeflinger, Leonhard ReindlAbstract:AbstractMotion tracking of thorax kinematics can be used to determine respiration. However, determining a minimal sensor configuration from 64 candidate sensor locations is associated with high computational costs. Hence, a hierarchical optimization method was proposed to determine the optimal combination of sensors. The hierarchical method was assessed by its ability to quickly determine the sensor combination that will yield optimal modelled tidal volume compared to Body Plethysmograph measurements. This method was able to find the optimal sensor combinations, in approximately 2% of the estimated time required by an exhaustive search.
Urs Frey - One of the best experts on this subject based on the ideXlab platform.
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Assessment of an infant whole-Body Plethysmograph using an infant lung function model
The European respiratory journal, 2001Co-Authors: B. Reinmann, J. Stocks, Urs FreyAbstract:In order to facilitate international multicentre studies and improve the quality control of infant pulmonary function measurements, the European Respiratory Society-American Thoracic Society Task Force for infant lung function testing has recently developed specifications for standardized infant lung function equipment and software. A mechanical infant lung model analogue has been developed to assess whether infant lung function equipment is able to meet these requirements. However, the practical testing of infant lung function equipment using such models is highly complex because of the need to use very small pressure and flow changes, and the numerous potentially confounding factors associated with both the design of the device and the testing procedure. The aim of this study was to determine whether the infant lung model is capable of assessing the overall function of an whole-Body infant- Plethysmograph, using the only infant Plethysmograph that was commercially available at the time as an example. The mechanical characteristics of the model such as vibrations or noise did not disturb the delicate Plethysmographic measurements and thereby allowed a reliable assessment of the system. A series of tests revealed that the Plethysmograph was able to measure airway resistance 1–3.5 kPa·L−1·s with an accuracy of ±2.5% and lung volumes 75–300 mL with an accuracy of ±2.5% under in vitro conditions. To conclude, the infant lung model is a useful means of assessing the overall in vitro performance of infant whole-Body Plethysmographs, but thermal, mechanical and frequency response characteristics of such a device must be taken into account when interpreting the results of such assessments.