The Experts below are selected from a list of 42 Experts worldwide ranked by ideXlab platform

Keiichi Ohno - One of the best experts on this subject based on the ideXlab platform.

  • Crystal structure of 1,10-dibromodecane and its infrared intensity in a urea clathrate and in the crystal.
    Spectrochimica acta. Part A Molecular and biomolecular spectroscopy, 2004
    Co-Authors: Isao Kanesaka, Sachie Matsuzawa, Tsutomu Ishioka, Yasuyuki Kitagawa, Keiichi Ohno
    Abstract:

    Abstract The crystal structure of 1,10-dibromodecane belongs to the monoclinic system and the space group is P2 1 /c with lattice dimensions of a =5.4574(3) A, b =5.2814(4) A, c =21.088(1) A and β =92.897(2)° and z =2. Infrared spectra of 1,10-dibromodecane in a urea clathrate and in the crystal were observed to investigate the effect of molecular interaction on infrared intensity. The infrared intensity of the CH 2 waggings in the crystalline state is 1.5–1.9 times stronger on the relative basis than that in a urea clathrate, whereas those of CH 2 stretching, CH 2 rocking and CH 2 bending are almost the same in both states. The former enhancement is explained in terms of increase in the Bond Moment of the C α H 2 group on the basis of crystal structure and the electrostatic model. The relative intensity of two CH 2 asymmetric stretching changes between the two states. This is also analyzed by the use of the electrostatic model.

Isao Kanesaka - One of the best experts on this subject based on the ideXlab platform.

  • Crystal structure of 1,10-dibromodecane and its infrared intensity in a urea clathrate and in the crystal.
    Spectrochimica acta. Part A Molecular and biomolecular spectroscopy, 2004
    Co-Authors: Isao Kanesaka, Sachie Matsuzawa, Tsutomu Ishioka, Yasuyuki Kitagawa, Keiichi Ohno
    Abstract:

    Abstract The crystal structure of 1,10-dibromodecane belongs to the monoclinic system and the space group is P2 1 /c with lattice dimensions of a =5.4574(3) A, b =5.2814(4) A, c =21.088(1) A and β =92.897(2)° and z =2. Infrared spectra of 1,10-dibromodecane in a urea clathrate and in the crystal were observed to investigate the effect of molecular interaction on infrared intensity. The infrared intensity of the CH 2 waggings in the crystalline state is 1.5–1.9 times stronger on the relative basis than that in a urea clathrate, whereas those of CH 2 stretching, CH 2 rocking and CH 2 bending are almost the same in both states. The former enhancement is explained in terms of increase in the Bond Moment of the C α H 2 group on the basis of crystal structure and the electrostatic model. The relative intensity of two CH 2 asymmetric stretching changes between the two states. This is also analyzed by the use of the electrostatic model.

Harold Kohn - One of the best experts on this subject based on the ideXlab platform.

  • Fluorine-substituted dihydrobicyclomycins: synthesis and biochemical and biological properties.
    Bioorganic & medicinal chemistry, 2005
    Co-Authors: Boon Saeng Park, William R. Widger, Harold Kohn
    Abstract:

    Many studies show that selective introduction of fluorine within pharmacological agents leads to improved activities. In this study, we determine the effects of aryl fluorine substitution in 5a-(benzylsulfanyl)-dihydrobicyclomycin (3) on the in vitro inhibition of Escherichia coli rho-dependent ATPase activity. Compound 3 is an analog of bicyclomycin (1), which is the only known selective inhibitor of rho, and 1 and 3 have comparable in vitro inhibitory activities. We demonstrate that aryl fluorine substitution of 3 leads to increase in inhibitory activity but that the beneficial effects due to fluorine were dependent upon the site and number of fluorine substituents. The bioactivities are rationalized in terms of the Bond Moment created by the aryl fluoride Bond within the 5a-aryl dihydrobicyclomycin-rho-binding pocket. Use of this hypothesis led to the design of dihydrobicyclomycin derivatives with superior in vitro rho inhibitory activities.

B. Subba - One of the best experts on this subject based on the ideXlab platform.

  • Dielectric studies of binary mixtures of 1-chloromethylnaphthalene with non polar solvents
    2011
    Co-Authors: Nv . Poornachandra Rao, B. Subba
    Abstract:

    The electric dipole Moments, Kirkwood correlation factors of dielectric polarization and the dielectric virial coefficients for 1-chloromethylnaphthalene in non polar solvents benzene and carbontetrachloride are estimated. The estimated dipole Moments are compared and analyzed with the sum of their Bond Moment values. The deviation in the estimated dipole Moments when compared with the dipole Moments estimated as a sum of their Bond Moments are attributed to the hyper conjugation and inductive effects. The estimated dipole Moments, Kirkwood correlation factors of dielectric polarization and the solution virial coefficients are correlated to understand the nature of intermolecular interactions in binary mixture of 1chloromethylnaphthalene dissolved in two non-polar solvents.

Achim Müller - One of the best experts on this subject based on the ideXlab platform.