The Experts below are selected from a list of 222 Experts worldwide ranked by ideXlab platform
V. Patterson - One of the best experts on this subject based on the ideXlab platform.
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Long-term stabilization after Bone Marrow Transplantation in juvenile metachromatic leukodystrophy
Archives of neurology, 1998Co-Authors: D. Kidd, J. Nelson, F. Jones, H. Dusoir, I. Wallace, S. Mckinstry, V. PattersonAbstract:We describe a 16-year-old boy with juvenile metachromatic leukodystrophy who was treated with Bone Marrow Transplantation. Follow-up over 8 years showed no increase in symptoms, no progression of neurological signs, and no neuropsychological deterioration. We conclude that Bone Marrow Transplantation may increase brain levels of arylsulfatase A enough to prevent deterioration in patients with juvenile metachromatic leukodystrophy.
Jun Okamura - One of the best experts on this subject based on the ideXlab platform.
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Unrelated Bone Marrow Transplantation using a reduced intensity-conditioning regimen in leukocyte adhesion deficiency.
Bone Marrow Transplantation, 2006Co-Authors: Daijiro Takahashi, Yoshihisa Nagatoshi, Yusuke Saito, Jun Nagayama, Yuichi Shinkoda, Jiro Inagaki, Kyoko Fujita, Jun OkamuraAbstract:Unrelated Bone Marrow Transplantation using a reduced intensity-conditioning regimen in leukocyte adhesion deficiency
Haydar Frangoul - One of the best experts on this subject based on the ideXlab platform.
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Matched unrelated Bone Marrow Transplantation with reduced-intensity conditioning for leukocyte adhesion deficiency
Bone Marrow Transplantation, 2006Co-Authors: Michael E. Engel, T. R. Bauer, C Calder, Becky Manes, Daniel D Hickstein, Haydar FrangoulAbstract:Matched unrelated Bone Marrow Transplantation with reduced-intensity conditioning for leukocyte adhesion deficiency
Chiara Messina - One of the best experts on this subject based on the ideXlab platform.
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Successful unrelated Bone Marrow Transplantation for Shwachman-Diamond syndrome.
Bone Marrow Transplantation, 2001Co-Authors: Simone Cesaro, M. V. Gazzola, R Destro, Stefania Varotto, Elisabetta Calore, Luigi Zanesco, Graziella Guariso, Chiara MessinaAbstract:A 5-year-old boy with Shwachman-Diamond syndrome underwent unrelated HLA-identical Bone Marrow Transplantation for severe pancytopenia. Conditioning was with busulfan, thiotepa and cyclophosphamide plus rabbit anti-lymphocyte serum. Engraftment for neutrophils and platelets was observed on days +18 and +41, respectively. Transplant-related side-effects were mild and transient. After a follow-up of 32 months, the patient is alive and enjoys a normal life, off any immunosuppressives. Immunological and hematological reconstitution is complete while other phenotypic characteristics (pancreatic insufficiency, short stature, femur dysostosis) are stable. Although experience in this field is scarce, we speculate that Bone Marrow failure in Shwachman-Diamond syndrome (even if not linked to the appearance of clonal disorders or leukemic transformation) is an indication for Bone Marrow Transplantation and may be associated with a better outcome.
D. Kidd - One of the best experts on this subject based on the ideXlab platform.
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Long-term stabilization after Bone Marrow Transplantation in juvenile metachromatic leukodystrophy
Archives of neurology, 1998Co-Authors: D. Kidd, J. Nelson, F. Jones, H. Dusoir, I. Wallace, S. Mckinstry, V. PattersonAbstract:We describe a 16-year-old boy with juvenile metachromatic leukodystrophy who was treated with Bone Marrow Transplantation. Follow-up over 8 years showed no increase in symptoms, no progression of neurological signs, and no neuropsychological deterioration. We conclude that Bone Marrow Transplantation may increase brain levels of arylsulfatase A enough to prevent deterioration in patients with juvenile metachromatic leukodystrophy.