The Experts below are selected from a list of 1287 Experts worldwide ranked by ideXlab platform
Jeremy K Cockcroft - One of the best experts on this subject based on the ideXlab platform.
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a novel ammonium pentaborate poly ethylene glycol templated polymer inclusion compound
Chemical Communications, 2019Co-Authors: Ar Ploszajski, Matthew Billing, Neal T Skipper, Jeremy K CockcroftAbstract:A new hydrogen-bonded supramolecular framework is reported, consisting of ammonium pentaborate, containing poly(ethylene-glycol) chains extending down tubular cavities in the structure. The crystal architecture is templated by the presence of the polyether chains, analogous to template synthesis of zeolites and metal organic frameworks. The ammonium pentaborate is formed by the thermolysis of ammonia borane, followed by hydrolysis of the dehydrogenation products by ambient water. This structure represents the first known example of a borate-based polymer inclusion compound.
Neal T Skipper - One of the best experts on this subject based on the ideXlab platform.
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a novel ammonium pentaborate poly ethylene glycol templated polymer inclusion compound
Chemical Communications, 2019Co-Authors: Ar Ploszajski, Matthew Billing, Neal T Skipper, Jeremy K CockcroftAbstract:A new hydrogen-bonded supramolecular framework is reported, consisting of ammonium pentaborate, containing poly(ethylene-glycol) chains extending down tubular cavities in the structure. The crystal architecture is templated by the presence of the polyether chains, analogous to template synthesis of zeolites and metal organic frameworks. The ammonium pentaborate is formed by the thermolysis of ammonia borane, followed by hydrolysis of the dehydrogenation products by ambient water. This structure represents the first known example of a borate-based polymer inclusion compound.
Ar Ploszajski - One of the best experts on this subject based on the ideXlab platform.
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a novel ammonium pentaborate poly ethylene glycol templated polymer inclusion compound
Chemical Communications, 2019Co-Authors: Ar Ploszajski, Matthew Billing, Neal T Skipper, Jeremy K CockcroftAbstract:A new hydrogen-bonded supramolecular framework is reported, consisting of ammonium pentaborate, containing poly(ethylene-glycol) chains extending down tubular cavities in the structure. The crystal architecture is templated by the presence of the polyether chains, analogous to template synthesis of zeolites and metal organic frameworks. The ammonium pentaborate is formed by the thermolysis of ammonia borane, followed by hydrolysis of the dehydrogenation products by ambient water. This structure represents the first known example of a borate-based polymer inclusion compound.
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A novel ammonium pentaborate – poly(ethylene-glycol) templated polymer-inclusion compound
2019Co-Authors: Ar Ploszajski, Billing M, Nt Skipper, Jk CockcroftAbstract:A new hydrogen-bonded supramolecular framework is reported, consisting of ammonium pentaborate, containing poly(ethylene-glycol) chains extending down tubular cavities in the structure. The crystal architecture is templated by the presence of the polyether chains, analogous to template synthesis of zeolites and metal organic frameworks. The ammonium pentaborate is formed by the thermolysis of ammonia borane, followed by hydrolysis of the dehydrogenation products by ambient water. This structure represents the first known example of a borate-based polymer inclusion compound
Sara Soleimani Asl - One of the best experts on this subject based on the ideXlab platform.
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Effect of Borage on hipocampal TNF-α α α α α protein and gene in the Amyloid β β β β β-Peptide(25-35)-Induced of Alzheimer model in rat
2020Co-Authors: Ehsan Barati, Sara Soleimani Asl, Seyed Ali Pourbakhsh, Mahmoud Jamshidian, Siamak ShahidiAbstract:Alzheimer's disease (AD) is a neurodegenerative disorder and most common form of dementia that leads to memory impairment. In the present study we have examined the investigating effect of Borago officinale on hipocampal TNF-α α α α α protein in the Beta Amyloid peptid induced of inflammation in the rat. Wistar male rats received intrahippocampal (IHP) injection of the Aβ β β β β(25-35) and Borage extract orally (100 mg/ kg).inflamation was confirmed by pathologist.in order to measure the expression of the TNF-α α α α α gene , RT-PCR method and for extraction of the TNF-α α α α α protein western bloting method was used. results showed that using Borage lead to reduce TNF-α α α α α gene and protein. This data suggests that Borage could improve the reduction of inflammation factors such as TNF-α α α α α and Borage consumption may lead to an improvement of ADinduced cognitive dysfunction
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the protective effect of borago officinalis extract on amyloid β 25 35 induced long term potentiation disruption in the dentate gyrus of male rats
Metabolic Brain Disease, 2015Co-Authors: Somayeh Zargooshnia, Fatemeh Ghahremanitamadon, Siamak Shahidi, Ali Nikkhah, Mehdi Mehdizadeh, Sara Soleimani AslAbstract:Alzheimer's disease (AD) begins with impairment in synaptic functions before developing into later neurodegeneration and neural loss. In the present study we have examined the protective effects of Borago Officinalis (Borage) extract on amyloid β (Aβ)--Induced long term potentiation (LTP) disruption in hippocampal dentate gyrus (DG). Wistar male rats received intrahippocampal (IHP) injection of the Aβ (25-35) and Borage extract throughout gestation (100 mg/kg). LTP in perforant path- DG synapses was assessed using electrophysiology method and field excitatory post- synaptic potential (fEPSP) slope and population spike (PS) amplitude were measured by 400 Hz tetanization. Finally, the total thiol content of hippocampus was measured using colorimetric reaction based on the Ellman's method. The results showed that Aβ (25-35) significantly decreased fEPSP slope and SP amplitude comparing with the control and sham group, whereas Borage extract administration increased these parameters compared to the Aβ group. Aβ induced a remarkable decrease in total thiol content of hippocampus and Borage prevented the decrease of the hippocampal total sulfhydryl (SH) groups. This data suggest that Aβ (25-35) can effectively inhibit LTP in the granular cells of the DG in hippocampus, and Borage supplementation reverse the synaptic plasticity in DG following Aβ treatment and that Borage consumption may lead to an improvement of AD-induced cognitive dysfunction.
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protective effects of borago officinalis extract on amyloid β peptide 25 35 induced memory impairment in male rats a behavioral study
BioMed Research International, 2014Co-Authors: Fatemeh Ghahremanitamadon, Siamak Shahidi, Somayeh Zargooshnia, Ali Nikkhah, Akram Ranjbar, Sara Soleimani AslAbstract:Alzheimer’s disease (AD) is a neurodegenerative disorder and most common form of dementia that leads to memory impairment. In the present study we have examined the protective effects of Borago officinalis (Borage) extract on Amyloid β (Aβ)-Induced memory impairment. Wistar male rats received intrahippocampal (IHP) injection of the Aβ(25–35) and Borage extract throughout gestation (100 mg/kg). Learning and memory functions in the rats were examined by the passive avoidance and the Morris water maze (MWM) tasks. Finally, the antioxidant capacity of hippocampus was measured using ferric ion reducing antioxidant power (FRAP) assay. The results showed that Aβ(25–35) impaired step-through latency and time in dark compartment in passive avoidance task. In the MWM, Aβ(25–35) significantly increased escape latency and traveled distance. Borage administration attenuated the Aβ-induced memory impairment in both the passive avoidance and the MWM tasks. Aβ induced a remarkable decrease in antioxidant power (FRAP value) of hippocampus and Borage prevented the decrease of the hippocampal antioxidant status. This data suggests that Borage could improve the learning impairment and oxidative damage in the hippocampal tissue following Aβ treatment and that Borage consumption may lead to an improvement of AD-induced cognitive dysfunction.
Matthew Billing - One of the best experts on this subject based on the ideXlab platform.
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a novel ammonium pentaborate poly ethylene glycol templated polymer inclusion compound
Chemical Communications, 2019Co-Authors: Ar Ploszajski, Matthew Billing, Neal T Skipper, Jeremy K CockcroftAbstract:A new hydrogen-bonded supramolecular framework is reported, consisting of ammonium pentaborate, containing poly(ethylene-glycol) chains extending down tubular cavities in the structure. The crystal architecture is templated by the presence of the polyether chains, analogous to template synthesis of zeolites and metal organic frameworks. The ammonium pentaborate is formed by the thermolysis of ammonia borane, followed by hydrolysis of the dehydrogenation products by ambient water. This structure represents the first known example of a borate-based polymer inclusion compound.