The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform

Anne Hansen - One of the best experts on this subject based on the ideXlab platform.

Frank L. Margolis - One of the best experts on this subject based on the ideXlab platform.

  • Imaging Ca2+-transients in single dendritic knobs of mouse OSNs in situ.
    2013
    Co-Authors: Hyun J. Kwon, Jae Hyung Koo, Frank Zufall, Trese Leinders-zufall, Frank L. Margolis
    Abstract:

    A–B, Low resolution transmitted light (A) and confocal fluoresence image in pseudocolor (B) of the olfactory epithelium preparation at rest. Scale bar, 5 µm. Multiple olfactory knobs are clearly visible (white arrows). A single Bowman Gland (arrowhead) is also identifiable based on its size and shape. C, Resting fluorescence Ca2+ signal superimposed onto the anatomical map. D, E, High resolution transmitted light (D) and confocal fluorescence image (E) of the olfactory knob delimited by the black box in A (arrow). F–I, Time series images of the same knob shown at rest (F), after focal application of a 1-s IBMX pulse (100 µM) (G–H), and following recovery of the fluorescence signal (I). The time points at which these images were acquired are indicated in (J). J, Analysis of the time course of the IBMX-evoked Ca2+ signal. The response was reversibly abolished by lowering the external Ca2+ concentration from 1 mM (normal Ca2+) to 0.6 µM (low Ca2+).

Hyun J. Kwon - One of the best experts on this subject based on the ideXlab platform.

  • Imaging Ca2+-transients in single dendritic knobs of mouse OSNs in situ.
    2013
    Co-Authors: Hyun J. Kwon, Jae Hyung Koo, Frank Zufall, Trese Leinders-zufall, Frank L. Margolis
    Abstract:

    A–B, Low resolution transmitted light (A) and confocal fluoresence image in pseudocolor (B) of the olfactory epithelium preparation at rest. Scale bar, 5 µm. Multiple olfactory knobs are clearly visible (white arrows). A single Bowman Gland (arrowhead) is also identifiable based on its size and shape. C, Resting fluorescence Ca2+ signal superimposed onto the anatomical map. D, E, High resolution transmitted light (D) and confocal fluorescence image (E) of the olfactory knob delimited by the black box in A (arrow). F–I, Time series images of the same knob shown at rest (F), after focal application of a 1-s IBMX pulse (100 µM) (G–H), and following recovery of the fluorescence signal (I). The time points at which these images were acquired are indicated in (J). J, Analysis of the time course of the IBMX-evoked Ca2+ signal. The response was reversibly abolished by lowering the external Ca2+ concentration from 1 mM (normal Ca2+) to 0.6 µM (low Ca2+).

Jae Hyung Koo - One of the best experts on this subject based on the ideXlab platform.

  • Imaging Ca2+-transients in single dendritic knobs of mouse OSNs in situ.
    2013
    Co-Authors: Hyun J. Kwon, Jae Hyung Koo, Frank Zufall, Trese Leinders-zufall, Frank L. Margolis
    Abstract:

    A–B, Low resolution transmitted light (A) and confocal fluoresence image in pseudocolor (B) of the olfactory epithelium preparation at rest. Scale bar, 5 µm. Multiple olfactory knobs are clearly visible (white arrows). A single Bowman Gland (arrowhead) is also identifiable based on its size and shape. C, Resting fluorescence Ca2+ signal superimposed onto the anatomical map. D, E, High resolution transmitted light (D) and confocal fluorescence image (E) of the olfactory knob delimited by the black box in A (arrow). F–I, Time series images of the same knob shown at rest (F), after focal application of a 1-s IBMX pulse (100 µM) (G–H), and following recovery of the fluorescence signal (I). The time points at which these images were acquired are indicated in (J). J, Analysis of the time course of the IBMX-evoked Ca2+ signal. The response was reversibly abolished by lowering the external Ca2+ concentration from 1 mM (normal Ca2+) to 0.6 µM (low Ca2+).

Frank Zufall - One of the best experts on this subject based on the ideXlab platform.

  • Imaging Ca2+-transients in single dendritic knobs of mouse OSNs in situ.
    2013
    Co-Authors: Hyun J. Kwon, Jae Hyung Koo, Frank Zufall, Trese Leinders-zufall, Frank L. Margolis
    Abstract:

    A–B, Low resolution transmitted light (A) and confocal fluoresence image in pseudocolor (B) of the olfactory epithelium preparation at rest. Scale bar, 5 µm. Multiple olfactory knobs are clearly visible (white arrows). A single Bowman Gland (arrowhead) is also identifiable based on its size and shape. C, Resting fluorescence Ca2+ signal superimposed onto the anatomical map. D, E, High resolution transmitted light (D) and confocal fluorescence image (E) of the olfactory knob delimited by the black box in A (arrow). F–I, Time series images of the same knob shown at rest (F), after focal application of a 1-s IBMX pulse (100 µM) (G–H), and following recovery of the fluorescence signal (I). The time points at which these images were acquired are indicated in (J). J, Analysis of the time course of the IBMX-evoked Ca2+ signal. The response was reversibly abolished by lowering the external Ca2+ concentration from 1 mM (normal Ca2+) to 0.6 µM (low Ca2+).