The Experts below are selected from a list of 285 Experts worldwide ranked by ideXlab platform

Diederik Van De Beek - One of the best experts on this subject based on the ideXlab platform.

  • anti infective treatment of Brain Abscess
    Expert Review of Anti-infective Therapy, 2018
    Co-Authors: Jacob Bodilsen, Matthijs C Brouwer, Henrik Nielsen, Diederik Van De Beek
    Abstract:

    ABSTRACTIntroduction: Brain Abscess is an uncommon and potentially life-threatening infection of the CNS that can be caused by a range of different pathogens including bacteria, fungi, and parasites. A multidisciplinary approach is important and anti-infective treatment remains crucial. Here, we review anti-infective treatment of Brain Abscess.Areas covered: We used the terms ‘(Brain Abscess[ti] AND (antibiotic* OR treatment)) NOT case report’), to conduct a search in the PubMed. Additional papers were identified by cross-reference checking and by browsing textbooks of infectious diseases and neurology.Commentary: Empiric treatment of bacterial Brain Abscess consists of cefotaxime and metronidazole with the addition of vancomycin if meticilline-resistant Staphylococcus aureus is suspected. For severely immuno-suppressed patients, for example transplant recipients, voriconazole and trimethoprim-sulfamethoxazole or sulfadiazine should be added. Increased knowledge of the pharmacokinetic profile of anti-infe...

  • Brain Abscess.
    The New England journal of medicine, 2014
    Co-Authors: Matthijs C Brouwer, Allan R Tunkel, Guy M Mckhann, Diederik Van De Beek
    Abstract:

    Despite advances in diagnostic techniques and treatment, Brain Abscess remains a challenging clinical problem with substantial case fatality rates. Delays in diagnosis and treatment can result in a poor outcome. This review summarizes current approaches to effective treatmen

Wayne L Gold - One of the best experts on this subject based on the ideXlab platform.

  • pyogenic Brain Abscess caused by streptococcus pneumoniae case report and review
    Clinical Infectious Diseases, 1997
    Co-Authors: Elizabeth Grigoriadis, Wayne L Gold
    Abstract:

    While Streptococcus pneumoniae is the most common cause of bacterial meningitis in adults, cases of pneumococcal Brain Abscess have rarely been reported. We describe a case of otogenic Brain Abscess caused by S. pneumoniae that developed in a patient who was receiving ciprofloxacin for the empirical treatment of otitis media. We also review 23 additional cases of pyogenic Brain Abscess caused by S. pneumoniae that have previously been reported. The development of a pneumococcal Brain Abscess was associated with a contiguous intracranial focus of infection in 50% of cases. The majority of patients presented with headache (81%) and focal neurological deficits (86%). However, the classic triad of headache, fever, and focal neurological deficits was present in only 24% of patients. The mortality rate for patients with Brain Abscess caused by S. pneumoniae was 35%; persistent neurological deficits were documented in 40% of patients who survived.

Elizabeth Grigoriadis - One of the best experts on this subject based on the ideXlab platform.

  • pyogenic Brain Abscess caused by streptococcus pneumoniae case report and review
    Clinical Infectious Diseases, 1997
    Co-Authors: Elizabeth Grigoriadis, Wayne L Gold
    Abstract:

    While Streptococcus pneumoniae is the most common cause of bacterial meningitis in adults, cases of pneumococcal Brain Abscess have rarely been reported. We describe a case of otogenic Brain Abscess caused by S. pneumoniae that developed in a patient who was receiving ciprofloxacin for the empirical treatment of otitis media. We also review 23 additional cases of pyogenic Brain Abscess caused by S. pneumoniae that have previously been reported. The development of a pneumococcal Brain Abscess was associated with a contiguous intracranial focus of infection in 50% of cases. The majority of patients presented with headache (81%) and focal neurological deficits (86%). However, the classic triad of headache, fever, and focal neurological deficits was present in only 24% of patients. The mortality rate for patients with Brain Abscess caused by S. pneumoniae was 35%; persistent neurological deficits were documented in 40% of patients who survived.

James A. Giglio - One of the best experts on this subject based on the ideXlab platform.

Matthijs C Brouwer - One of the best experts on this subject based on the ideXlab platform.

  • anti infective treatment of Brain Abscess
    Expert Review of Anti-infective Therapy, 2018
    Co-Authors: Jacob Bodilsen, Matthijs C Brouwer, Henrik Nielsen, Diederik Van De Beek
    Abstract:

    ABSTRACTIntroduction: Brain Abscess is an uncommon and potentially life-threatening infection of the CNS that can be caused by a range of different pathogens including bacteria, fungi, and parasites. A multidisciplinary approach is important and anti-infective treatment remains crucial. Here, we review anti-infective treatment of Brain Abscess.Areas covered: We used the terms ‘(Brain Abscess[ti] AND (antibiotic* OR treatment)) NOT case report’), to conduct a search in the PubMed. Additional papers were identified by cross-reference checking and by browsing textbooks of infectious diseases and neurology.Commentary: Empiric treatment of bacterial Brain Abscess consists of cefotaxime and metronidazole with the addition of vancomycin if meticilline-resistant Staphylococcus aureus is suspected. For severely immuno-suppressed patients, for example transplant recipients, voriconazole and trimethoprim-sulfamethoxazole or sulfadiazine should be added. Increased knowledge of the pharmacokinetic profile of anti-infe...

  • Brain Abscess.
    The New England journal of medicine, 2014
    Co-Authors: Matthijs C Brouwer, Allan R Tunkel, Guy M Mckhann, Diederik Van De Beek
    Abstract:

    Despite advances in diagnostic techniques and treatment, Brain Abscess remains a challenging clinical problem with substantial case fatality rates. Delays in diagnosis and treatment can result in a poor outcome. This review summarizes current approaches to effective treatmen