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K Kikuchi - One of the best experts on this subject based on the ideXlab platform.
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Association of postoperative Brain Dysfunction and atherosclerosis, intraoperative rSO2 and CO2 reaction in open heart surgery
Masui. The Japanese journal of anesthesiology, 1996Co-Authors: A Konishi, K KikuchiAbstract:We studied the relationship between postoperative Brain Dysfunction and the state of atherosclerosis in the patients of open heart surgery, by analyzing the intraoperative cerebral oxygen saturation (rSO2) and the CO2 reaction. The subjects were 143 patients with average age of 64 years. The patients with low postoperative Hasegawa's Dementia Score were categorized as Brain Dysfunction group. rSO2 was utilized to monitor cerebral blood flow, and AI and stiffness parameter beta were used for evaluation of systemic atherosclerosis. Postoperative Brain Dysfunction was confirmed in 12%. There were significantly high values of AI and beta as well as low rSO2, in elder age with low cardiac index and no correlation was observed between rSO2 and PaCO2 in the Brain Dysfunction group. The results suggested that a higher level of atherosclerosis is associated with the postoperative Brain Dysfunction with resultant decreased cerebral blood flow and disturbed reaction to CO2 of cerebral blood vessels.
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Cerebral oxygen saturation (rSo2) during open heart surgery and postoperative Brain Dysfunction
Masui. The Japanese journal of anesthesiology, 1995Co-Authors: A Konishi, K KikuchiAbstract:We studied the occurrence of Brain Dysfunction in regards to changes in cerebral oxygen saturation (rSo2) during open heart surgery. The subjects were 68 patients with the average age of 61 years. For the evaluation of Brain function, Hasegawa Dementia Scale was used, and those patients whose scores were less than 23 points, or had decreased by more than 3 points from preoperative scores on the 7th postoperative day were categorized as the Brain Dysfunction group. There were 14 (21%) postoperative Brain Dysfunction cases. Although rSo2 values during surgery ran at 70-65% level, the Brain Dysfunction group showed significantly lower values throughout the entire procedures, with the lowest value being 61% during cardiopulmonary bypass. The patients in the Dysfunction group were of older ages and postoperative lower cardiac index, which indicated that the occurrence of Brain Dysfunction is greatly influenced by low cerebral blood flow. Effect from the operative procedures and CPB alone seemed to be small. Cerebral oxygen saturation (rSo2) is believed to be a useful monitor of cerebral blood flow, and occurrence of Brain Dysfunction may be expected at values lower than 60%.
Judith E. Nelson - One of the best experts on this subject based on the ideXlab platform.
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Risk Factors for Long-Term Brain Dysfunction after Chronic Critical Illness
Annals of the American Thoracic Society, 2013Co-Authors: Aluko A. Hope, R. Sean Morrison, Sylvan Wallenstein, Judith E. NelsonAbstract:Rationale: Factors associated with long-term Brain Dysfunction (LTBD) in survivors of chronic critical illness (CCI) have not been explored but may be important for clinical practice and planning by patients, families, and providers. Objectives: To identify risk factors for LTBD after treatment for CCI and to explore the association between acute delirium and coma during hospital treatment and LTBD. Methods: A prospective cohort study of adults admitted to a respiratory care unit for treatment of CCI. Measurements and Main Results: Using the Confusion Assessment Method for ICU and the Richmond Agitation and Sedation Scale, we evaluated patients for delirium and coma during their hospital treatment for CCI. We collected data on other potential risk factors for LTBD by prospectively reviewing the patients’ medical records and interviewing surrogates. We contacted survivors by telephone at 6 months after discharge to assess Brain function using the telephone Confusion Assessment Method. Among 385 patients treated for CCI, 213 (56.1%) were dead at 6 months, and 108 of 167 (64.7%) of survivors were impaired. We used multinomial logistic regression in which the outcomes were (1) death, (2) Brain Dysfunction, and (3) survival without LTBD. Older patients, patients with higher Acute Physiology Score, and those with multiple complications during treatment for CCI were more likely to have LTBD. Acute Brain Dysfunction during hospital treatment was also associated with an increased risk of LTBD (odds ratio, 2.14; 95% confidence interval, 1.02–4.52). Conclusions: LTBD after treatment for CCI is associated with Brain Dysfunction during such treatment as well as with older age and higher severity of illness of the patients.
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Brain Dysfunction another burden for the chronically critically ill
JAMA Internal Medicine, 2006Co-Authors: Judith E. Nelson, Nidhi Tandon, Alice F Mercado, Sharon L Camhi, Wesley E Ely, Sean R MorrisonAbstract:Background Chronic critical illness is a devastating syndrome of prolonged respiratory failure and other derangements. To our knowledge, no previous research has addressed Brain Dysfunction in the chronically critically ill, although this topic is important for medical decision making. Methods We studied a prospective cohort of 203 consecutive, chronically critically ill adults transferred to our hospital's respiratory care unit (RCU) after tracheotomy for failure to wean. We measured prevalence and duration of coma and delirium during RCU treatment using the Confusion Assessment Method for the Intensive Care Unit with the Richmond Agitation-Sedation Scale. To assess survivors (at 3 and 6 months after RCU discharge), we used a validated telephone Confusion Assessment Method. Results Before hospitalization, most (153 [75.4%]) of the 203 patients in the study were at home, completely independent (115 [56.7%]), and cognitively intact (116 [82.0%]). In the RCU, 61 (30.0%) were comatose throughout the stay. Approximately half of patients (66 of 142) who were not in coma were delirious. Patients spent an average of 17.9 days (range, 1-153 days) in coma or delirium (average RCU stay, 25.6 days). Half of survivors (79 of 160) had one of these disturbances at RCU discharge. At 6 months, three fourths (151) of the study patients were dead or institutionalized; of 85 survivors, 58 (68.2%) were too profoundly impaired to respond to telephone cognitive assessment, and 53 (62.4%) were dependent in all activities of daily living. Conclusions Severe, prolonged, and permanent Brain Dysfunction is a prominent feature of chronic critical illness. These data, together with previous reports of symptom distress and rates of mortality and institutionalization, describe burdens for chronically critically ill patients receiving continued life-prolonging treatment and for their families.
Luzius A. Steiner - One of the best experts on this subject based on the ideXlab platform.
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Brain Dysfunction in sepsis: what can we learn from cerebral perfusion studies?
Critical Care, 2008Co-Authors: Luzius A. SteinerAbstract:Investigations on the relationship between sepsis, Brain Dysfunction, and cerebral perfusion are methodologically very difficult to perform. It is important to interpret the results of such studies in view of our limited ability to diagnose and quantify Brain Dysfunction and to consider our limited understanding of the mechanisms that lead to or are associated with Brain Dysfunction in sepsis.
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Commentary Brain Dysfunction in sepsis: what can we learn from cerebral perfusion studies?
2008Co-Authors: Luzius A. SteinerAbstract:Investigations on the relationship between sepsis, Brain Dysfunction, and cerebral perfusion are methodologically very difficult to perform. It is important to interpret the results of such studies in view of our limited ability to diagnose and quantify Brain Dysfunction and to consider our limited understanding of the mechanisms that lead to or are associated with Brain Dysfunction in sepsis.
A Konishi - One of the best experts on this subject based on the ideXlab platform.
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Association of postoperative Brain Dysfunction and atherosclerosis, intraoperative rSO2 and CO2 reaction in open heart surgery
Masui. The Japanese journal of anesthesiology, 1996Co-Authors: A Konishi, K KikuchiAbstract:We studied the relationship between postoperative Brain Dysfunction and the state of atherosclerosis in the patients of open heart surgery, by analyzing the intraoperative cerebral oxygen saturation (rSO2) and the CO2 reaction. The subjects were 143 patients with average age of 64 years. The patients with low postoperative Hasegawa's Dementia Score were categorized as Brain Dysfunction group. rSO2 was utilized to monitor cerebral blood flow, and AI and stiffness parameter beta were used for evaluation of systemic atherosclerosis. Postoperative Brain Dysfunction was confirmed in 12%. There were significantly high values of AI and beta as well as low rSO2, in elder age with low cardiac index and no correlation was observed between rSO2 and PaCO2 in the Brain Dysfunction group. The results suggested that a higher level of atherosclerosis is associated with the postoperative Brain Dysfunction with resultant decreased cerebral blood flow and disturbed reaction to CO2 of cerebral blood vessels.
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Cerebral oxygen saturation (rSo2) during open heart surgery and postoperative Brain Dysfunction
Masui. The Japanese journal of anesthesiology, 1995Co-Authors: A Konishi, K KikuchiAbstract:We studied the occurrence of Brain Dysfunction in regards to changes in cerebral oxygen saturation (rSo2) during open heart surgery. The subjects were 68 patients with the average age of 61 years. For the evaluation of Brain function, Hasegawa Dementia Scale was used, and those patients whose scores were less than 23 points, or had decreased by more than 3 points from preoperative scores on the 7th postoperative day were categorized as the Brain Dysfunction group. There were 14 (21%) postoperative Brain Dysfunction cases. Although rSo2 values during surgery ran at 70-65% level, the Brain Dysfunction group showed significantly lower values throughout the entire procedures, with the lowest value being 61% during cardiopulmonary bypass. The patients in the Dysfunction group were of older ages and postoperative lower cardiac index, which indicated that the occurrence of Brain Dysfunction is greatly influenced by low cerebral blood flow. Effect from the operative procedures and CPB alone seemed to be small. Cerebral oxygen saturation (rSo2) is believed to be a useful monitor of cerebral blood flow, and occurrence of Brain Dysfunction may be expected at values lower than 60%.
Peter Kuster - One of the best experts on this subject based on the ideXlab platform.
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Screening For Brain Dysfunction In Psychiatric Patients
2016Co-Authors: Peter KusterAbstract:screening for Brain Dysfunction in psychiatric patients is available in our digital library an online access to it is set as public so you can get it instantly. Our books collection spans in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the screening for Brain Dysfunction in psychiatric patients is universally compatible with any devices to read.