The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform
Kai Shan - One of the best experts on this subject based on the ideXlab platform.
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Stroke caused by an inflammatory thrombus: a case report
BMC Neurology, 2017Co-Authors: Kai ShanAbstract:Abstract Background Stroke is the leading cause of mortality and disability worldwide. Several definite risk factors have been identified for stroke, although infectious factors might also contribute to stroke episodes through increased susceptibility or direct induction. Case presentation A 46-year-old Chinese male initially presented with fever, headache, and impaired memory and developed disturbance of consciousness after admission. A clinical diagnosis of Staphylococcus aureus sepsis, massive cerebral infarction and haemorrhagic transformation (left internal carotid arterial system, inflammatory thrombus) were made based on Brain Radiography, blood culture and postoperative pathological examinations. These symptoms improved following antibiotic therapy with vancomycin and conventional treatments for stroke. Conclusion For stroke patients without traditional cerebrovascular risk factors but with signs of infection, infectious causes should be considered.
Wayseen Wang - One of the best experts on this subject based on the ideXlab platform.
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Prenatal diagnosis of de novo terminal deletion of chromosome 7q.
Prenatal Diagnosis, 2003Co-Authors: Chih-ping Chen, Schu-rern Chern, Tung-yao Chang, Chin-yuan Tzen, Wen-lin Chen, Wayseen WangAbstract:Objectives To present the prenatal diagnosis and perinatal findings of a de novo terminal deletion of chromosome 7q. Case Amniocentesis was performed at 21-weeks gestation owing to a positive result of maternal serum multiple-marker screening. The 30-year-old woman, gravida 2, para 1, had a maternal serum multiple-marker screening test at 18-weeks gestation. The risk of Down syndrome was 1/11 calculated from the gestational age, maternal age, a maternal serum α-fetoprotein level of 1.026 multiples of the median (MOM), and a maternal serum free β-human chorionic gonadotrophin (hCG) level of 8.678 MoM. Cytogenetic analysis of the cultured amniotic fluid cells revealed a de novo terminal deletion of 7q, 46,XX,del(7)(q35). Ultrasonography showed intrauterine growth restriction, microcephaly, and tetralogy of Fallot. The pregnancy was terminated subsequently. Grossly, the placenta was normal. On autopsy, the proband additionally manifested a prominent forehead, hypertelorism, epicanthus, upslanting palpebral fissures, a flat and broad nasal bridge, micrognathia, large low-set ears, overriding toes, and a normal Brain. Radiography demonstrated a normal spine. Fluorescence in situ hybridization analysis demonstrated a 7q terminal deletion. Genetic marker analysis showed a maternally derived terminal deletion of chromosome 7(q35–qter). Conclusion Fetuses with a de novo 7q terminal deletion may be associated with a markedly elevated maternal serum hCG level and abnormal sonographic findings of intrauterine growth restriction, microcephaly, and congenital heart defects in the second trimester. Copyright © 2003 John Wiley & Sons, Ltd.
Chih-ping Chen - One of the best experts on this subject based on the ideXlab platform.
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Prenatal diagnosis of de novo terminal deletion of chromosome 7q.
Prenatal Diagnosis, 2003Co-Authors: Chih-ping Chen, Schu-rern Chern, Tung-yao Chang, Chin-yuan Tzen, Wen-lin Chen, Wayseen WangAbstract:Objectives To present the prenatal diagnosis and perinatal findings of a de novo terminal deletion of chromosome 7q. Case Amniocentesis was performed at 21-weeks gestation owing to a positive result of maternal serum multiple-marker screening. The 30-year-old woman, gravida 2, para 1, had a maternal serum multiple-marker screening test at 18-weeks gestation. The risk of Down syndrome was 1/11 calculated from the gestational age, maternal age, a maternal serum α-fetoprotein level of 1.026 multiples of the median (MOM), and a maternal serum free β-human chorionic gonadotrophin (hCG) level of 8.678 MoM. Cytogenetic analysis of the cultured amniotic fluid cells revealed a de novo terminal deletion of 7q, 46,XX,del(7)(q35). Ultrasonography showed intrauterine growth restriction, microcephaly, and tetralogy of Fallot. The pregnancy was terminated subsequently. Grossly, the placenta was normal. On autopsy, the proband additionally manifested a prominent forehead, hypertelorism, epicanthus, upslanting palpebral fissures, a flat and broad nasal bridge, micrognathia, large low-set ears, overriding toes, and a normal Brain. Radiography demonstrated a normal spine. Fluorescence in situ hybridization analysis demonstrated a 7q terminal deletion. Genetic marker analysis showed a maternally derived terminal deletion of chromosome 7(q35–qter). Conclusion Fetuses with a de novo 7q terminal deletion may be associated with a markedly elevated maternal serum hCG level and abnormal sonographic findings of intrauterine growth restriction, microcephaly, and congenital heart defects in the second trimester. Copyright © 2003 John Wiley & Sons, Ltd.
Schu-rern Chern - One of the best experts on this subject based on the ideXlab platform.
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Prenatal diagnosis of de novo terminal deletion of chromosome 7q.
Prenatal Diagnosis, 2003Co-Authors: Chih-ping Chen, Schu-rern Chern, Tung-yao Chang, Chin-yuan Tzen, Wen-lin Chen, Wayseen WangAbstract:Objectives To present the prenatal diagnosis and perinatal findings of a de novo terminal deletion of chromosome 7q. Case Amniocentesis was performed at 21-weeks gestation owing to a positive result of maternal serum multiple-marker screening. The 30-year-old woman, gravida 2, para 1, had a maternal serum multiple-marker screening test at 18-weeks gestation. The risk of Down syndrome was 1/11 calculated from the gestational age, maternal age, a maternal serum α-fetoprotein level of 1.026 multiples of the median (MOM), and a maternal serum free β-human chorionic gonadotrophin (hCG) level of 8.678 MoM. Cytogenetic analysis of the cultured amniotic fluid cells revealed a de novo terminal deletion of 7q, 46,XX,del(7)(q35). Ultrasonography showed intrauterine growth restriction, microcephaly, and tetralogy of Fallot. The pregnancy was terminated subsequently. Grossly, the placenta was normal. On autopsy, the proband additionally manifested a prominent forehead, hypertelorism, epicanthus, upslanting palpebral fissures, a flat and broad nasal bridge, micrognathia, large low-set ears, overriding toes, and a normal Brain. Radiography demonstrated a normal spine. Fluorescence in situ hybridization analysis demonstrated a 7q terminal deletion. Genetic marker analysis showed a maternally derived terminal deletion of chromosome 7(q35–qter). Conclusion Fetuses with a de novo 7q terminal deletion may be associated with a markedly elevated maternal serum hCG level and abnormal sonographic findings of intrauterine growth restriction, microcephaly, and congenital heart defects in the second trimester. Copyright © 2003 John Wiley & Sons, Ltd.
Tung-yao Chang - One of the best experts on this subject based on the ideXlab platform.
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Prenatal diagnosis of de novo terminal deletion of chromosome 7q.
Prenatal Diagnosis, 2003Co-Authors: Chih-ping Chen, Schu-rern Chern, Tung-yao Chang, Chin-yuan Tzen, Wen-lin Chen, Wayseen WangAbstract:Objectives To present the prenatal diagnosis and perinatal findings of a de novo terminal deletion of chromosome 7q. Case Amniocentesis was performed at 21-weeks gestation owing to a positive result of maternal serum multiple-marker screening. The 30-year-old woman, gravida 2, para 1, had a maternal serum multiple-marker screening test at 18-weeks gestation. The risk of Down syndrome was 1/11 calculated from the gestational age, maternal age, a maternal serum α-fetoprotein level of 1.026 multiples of the median (MOM), and a maternal serum free β-human chorionic gonadotrophin (hCG) level of 8.678 MoM. Cytogenetic analysis of the cultured amniotic fluid cells revealed a de novo terminal deletion of 7q, 46,XX,del(7)(q35). Ultrasonography showed intrauterine growth restriction, microcephaly, and tetralogy of Fallot. The pregnancy was terminated subsequently. Grossly, the placenta was normal. On autopsy, the proband additionally manifested a prominent forehead, hypertelorism, epicanthus, upslanting palpebral fissures, a flat and broad nasal bridge, micrognathia, large low-set ears, overriding toes, and a normal Brain. Radiography demonstrated a normal spine. Fluorescence in situ hybridization analysis demonstrated a 7q terminal deletion. Genetic marker analysis showed a maternally derived terminal deletion of chromosome 7(q35–qter). Conclusion Fetuses with a de novo 7q terminal deletion may be associated with a markedly elevated maternal serum hCG level and abnormal sonographic findings of intrauterine growth restriction, microcephaly, and congenital heart defects in the second trimester. Copyright © 2003 John Wiley & Sons, Ltd.