The Experts below are selected from a list of 24 Experts worldwide ranked by ideXlab platform
Yukio Imamura - One of the best experts on this subject based on the ideXlab platform.
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Ischemic Pretreatment Delays Ischemic Brain Vasospasm Injury in Gerbils
Advances in experimental medicine and biology, 2014Co-Authors: Akitoshi Seiyama, Nao Yoshikawa, Yukio ImamuraAbstract:Three experiments were conducted for the present study. First, to elucidate the mechanism and functional significance underlying ischemic vasoconstriction, we investigated the relationship between arteriolar constriction and tissue energy metabolism during bilateral common carotid artery occlusion in gerbils. Second, to identify differences in the postischemic recovery of physiologic parameters between short and prolonged Brain ischemia, we measured changes in regional cerebral blood flow, microvessel diameter, Brain temperature, and electrophysiologic response. Third, to explore the physiological mechanism of ischemic tolerance, we studied vascular response and intracerebral oxygenation states after acute global ischemia with and without pretreatment by mild ischemic stress. Here, we identify one of the physiologic mechanisms of the ischemic tolerance caused by brief ischemic pretreatment.
Manoel Jacobsen Teixeira - One of the best experts on this subject based on the ideXlab platform.
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Brain Vasospasm after head injury.
Journal of neurosurgery, 2007Co-Authors: Edson Bor-seng-shu, Manoel Jacobsen TeixeiraAbstract:Object. The purpose of this prospective study was to evaluate the cumulative incidence, duration, and time course of cerebral Vasospasm after traumatic Brain injury (TBI) in a cohort of 299 patients. Methods. Transcranial Doppler (TCD) ultrasonography studies of blood flow velocity in the middle cerebral and basilar arteries (VMCA and VBA, respectively) were performed at regular intervals during the first 2 weeks posttrauma in association with 133Xe cerebral blood flow (CBF) measurements. According to current definitions of Vasospasm, five different criteria were used to classify the patients: A (VMCA > 120 cm/second); B (VMCA > 120 cm/second and a Lindegaard ratio [LR] > 3); C (spasm index [SI] in the anterior circulation > 3.4); D (VBA > 90 cm/second); and E (SI in the posterior circulation > 2.5). Criteria C and E were considered to represent hemodynamically significant Vasospasm. Mixed-effects spline models were used to analyze the data of multiple measurements with an inconsistent sampling rate. Over...
Akitoshi Seiyama - One of the best experts on this subject based on the ideXlab platform.
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Ischemic Pretreatment Delays Ischemic Brain Vasospasm Injury in Gerbils
Advances in experimental medicine and biology, 2014Co-Authors: Akitoshi Seiyama, Nao Yoshikawa, Yukio ImamuraAbstract:Three experiments were conducted for the present study. First, to elucidate the mechanism and functional significance underlying ischemic vasoconstriction, we investigated the relationship between arteriolar constriction and tissue energy metabolism during bilateral common carotid artery occlusion in gerbils. Second, to identify differences in the postischemic recovery of physiologic parameters between short and prolonged Brain ischemia, we measured changes in regional cerebral blood flow, microvessel diameter, Brain temperature, and electrophysiologic response. Third, to explore the physiological mechanism of ischemic tolerance, we studied vascular response and intracerebral oxygenation states after acute global ischemia with and without pretreatment by mild ischemic stress. Here, we identify one of the physiologic mechanisms of the ischemic tolerance caused by brief ischemic pretreatment.
Edson Bor-seng-shu - One of the best experts on this subject based on the ideXlab platform.
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Brain Vasospasm after head injury.
Journal of neurosurgery, 2007Co-Authors: Edson Bor-seng-shu, Manoel Jacobsen TeixeiraAbstract:Object. The purpose of this prospective study was to evaluate the cumulative incidence, duration, and time course of cerebral Vasospasm after traumatic Brain injury (TBI) in a cohort of 299 patients. Methods. Transcranial Doppler (TCD) ultrasonography studies of blood flow velocity in the middle cerebral and basilar arteries (VMCA and VBA, respectively) were performed at regular intervals during the first 2 weeks posttrauma in association with 133Xe cerebral blood flow (CBF) measurements. According to current definitions of Vasospasm, five different criteria were used to classify the patients: A (VMCA > 120 cm/second); B (VMCA > 120 cm/second and a Lindegaard ratio [LR] > 3); C (spasm index [SI] in the anterior circulation > 3.4); D (VBA > 90 cm/second); and E (SI in the posterior circulation > 2.5). Criteria C and E were considered to represent hemodynamically significant Vasospasm. Mixed-effects spline models were used to analyze the data of multiple measurements with an inconsistent sampling rate. Over...
Nao Yoshikawa - One of the best experts on this subject based on the ideXlab platform.
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Ischemic Pretreatment Delays Ischemic Brain Vasospasm Injury in Gerbils
Advances in experimental medicine and biology, 2014Co-Authors: Akitoshi Seiyama, Nao Yoshikawa, Yukio ImamuraAbstract:Three experiments were conducted for the present study. First, to elucidate the mechanism and functional significance underlying ischemic vasoconstriction, we investigated the relationship between arteriolar constriction and tissue energy metabolism during bilateral common carotid artery occlusion in gerbils. Second, to identify differences in the postischemic recovery of physiologic parameters between short and prolonged Brain ischemia, we measured changes in regional cerebral blood flow, microvessel diameter, Brain temperature, and electrophysiologic response. Third, to explore the physiological mechanism of ischemic tolerance, we studied vascular response and intracerebral oxygenation states after acute global ischemia with and without pretreatment by mild ischemic stress. Here, we identify one of the physiologic mechanisms of the ischemic tolerance caused by brief ischemic pretreatment.