The Experts below are selected from a list of 264 Experts worldwide ranked by ideXlab platform
Chung-ming Sun - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of Aminofuran-Linked Benzimidazoles and Cyanopyrrole-Fused Benzimidazoles by Condition-Based Skeletal Divergence
ACS combinatorial science, 2017Co-Authors: Wei-shun Hsu, Min-huan Tsai, Indrajeet J. Barve, Gorakh S. Yellol, Chung-ming SunAbstract:A condition-based skeletal divergent synthesis was explored to achieve skeletal diversity in two component condensation reaction. Cyanomethyl benzimidazole was reacted with α-Bromoketone under thermal conditions to furnish 2-aminofuranyl-benzimidazoles, while the same reaction afforded 3-cyano-benzopyrrolo-imidazoles under microwave irradiation. Two nonequivalent nucleophilic centers on benzimidazole moiety were manipulated elegantly by different reaction conditions to achieve the skeletal diversity.
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Synthesis of Aminofuran-Linked Benzimidazoles and Cyanopyrrole-Fused Benzimidazoles by Condition-Based Skeletal Divergence
2017Co-Authors: Wei-shun Hsu, Min-huan Tsai, Indrajeet J. Barve, Gorakh S. Yellol, Chung-ming SunAbstract:A condition-based skeletal divergent synthesis was explored to achieve skeletal diversity in two component condensation reaction. Cyanomethyl benzimidazole was reacted with α-Bromoketone under thermal conditions to furnish 2-aminofuranyl-benzimidazoles, while the same reaction afforded 3-cyano-benzopyrrolo-imidazoles under microwave irradiation. Two nonequivalent nucleophilic centers on benzimidazole moiety were manipulated elegantly by different reaction conditions to achieve the skeletal diversity
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Regioselective one-pot three component synthesis of chiral 2-iminoselenazolines under sonication
RSC Advances, 2015Co-Authors: Wong Jin Chang, Manohar V. Kulkarni, Chung-ming SunAbstract:A one-pot multi component reaction of selenoureas, which are in situ generated from L-amino esters and isoselenocyanates, with α-Bromoketone under ultrasonication. Selenourea and α-Bromoketones formed 2-iminoselenazoles through a Hantzsch selenazole-type reaction. The steric effect of the α-substituted Bromoketones on the rate of the tandem reaction was studied to understand the reaction mechanism by isolating the key reaction intermediate, 2-iminoselenol.
Michael B. Hursthouse - One of the best experts on this subject based on the ideXlab platform.
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Pyrrolo[1,2,3-de]quinoxalines: unexpected products from 1,3-dipolar cycloaddition of dihydroimidazolium ylides
Tetrahedron Letters, 2001Co-Authors: Raymond C. F. Jones, Jim Iley, Pedro M. J. Lory, Simon C. Coles, Mark E. Light, Michael B. HursthouseAbstract:4,5-Dihydroimidazoles undergo an N-alkylation and 1,3-dipolar cycloaddition cascade with unsaturated ?-Bromoketones, with subsequent eliminative ring-opening, recyclisation and tautomerisation to form unexpected hexahydropyrrolo[1,2,3-de]quinoxalines.
Jie-fei Cheng - One of the best experts on this subject based on the ideXlab platform.
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unprecedented formation of δ2 isoxazoline and or 1 nitroso pyrazoline from α Bromoketone oximes and diazo compounds
Tetrahedron Letters, 2009Co-Authors: Jianhua Guo, John A. Gaudette, Jie-fei ChengAbstract:Reaction of α-Bromoketone oximes with diazo compounds in the presence of a metal catalyst and base led to the unprecedented formation of two types of rings: Δ 2 -isoxazolines and 1-nitrosopyrazolines.
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Unprecedented formation of Δ2-isoxazoline and/or 1-nitroso-pyrazoline from α-Bromoketone oximes and diazo compounds
Tetrahedron Letters, 2009Co-Authors: Jianhua Guo, John A. Gaudette, Jie-fei ChengAbstract:Reaction of α-Bromoketone oximes with diazo compounds in the presence of a metal catalyst and base led to the unprecedented formation of two types of rings: Δ 2 -isoxazolines and 1-nitrosopyrazolines.
Bhisma K. Patel - One of the best experts on this subject based on the ideXlab platform.
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A new facile synthetic method for the construction of 1,3-oxathiolan-2-ylidenes
Tetrahedron Letters, 2008Co-Authors: Harisadhan Ghosh, Siva Murru, Veerababu Rao Kavala, C. B. Singh, Bhisma K. PatelAbstract:A new, convenient and efficient synthetic method for the construction of 1,3-oxathiolan-2-ylidenes via sodium borohydride reduction of the addition product of dithiocarbamic acid esters with α-Bromoketones under basic conditions is reported. This method is general and applicable to a range of systems.
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3 -aryl-1-benzoylthioureas with α-Bromoketones in water form 2-N-benzoyl-3-arylthiazol -2 (3H)-imines, not 3-aryl-1 -benzoylimidazoline-2-thiones
Journal of Chemical Research, 2007Co-Authors: C. B. Singh, Siva Murru, Veerababu Rao Kavala, Bhisma K. PatelAbstract:The products obtained by the reaction of 1-benzoyl-3-phenylthioureas with α-Bromoketones in water in the presence of triethylamine are not imidazoline-2-thiones as reported (J. Chem. Res. 2005, 689-690); rather they are thiazol-2-imine derivatives.
Wei-shun Hsu - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of Aminofuran-Linked Benzimidazoles and Cyanopyrrole-Fused Benzimidazoles by Condition-Based Skeletal Divergence
ACS combinatorial science, 2017Co-Authors: Wei-shun Hsu, Min-huan Tsai, Indrajeet J. Barve, Gorakh S. Yellol, Chung-ming SunAbstract:A condition-based skeletal divergent synthesis was explored to achieve skeletal diversity in two component condensation reaction. Cyanomethyl benzimidazole was reacted with α-Bromoketone under thermal conditions to furnish 2-aminofuranyl-benzimidazoles, while the same reaction afforded 3-cyano-benzopyrrolo-imidazoles under microwave irradiation. Two nonequivalent nucleophilic centers on benzimidazole moiety were manipulated elegantly by different reaction conditions to achieve the skeletal diversity.
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Synthesis of Aminofuran-Linked Benzimidazoles and Cyanopyrrole-Fused Benzimidazoles by Condition-Based Skeletal Divergence
2017Co-Authors: Wei-shun Hsu, Min-huan Tsai, Indrajeet J. Barve, Gorakh S. Yellol, Chung-ming SunAbstract:A condition-based skeletal divergent synthesis was explored to achieve skeletal diversity in two component condensation reaction. Cyanomethyl benzimidazole was reacted with α-Bromoketone under thermal conditions to furnish 2-aminofuranyl-benzimidazoles, while the same reaction afforded 3-cyano-benzopyrrolo-imidazoles under microwave irradiation. Two nonequivalent nucleophilic centers on benzimidazole moiety were manipulated elegantly by different reaction conditions to achieve the skeletal diversity
