The Experts below are selected from a list of 1074 Experts worldwide ranked by ideXlab platform
Miloš Kostov - One of the best experts on this subject based on the ideXlab platform.
-
1
2016Co-Authors: Miloš Stanković, Miloš Kostov, Ph. DAbstract:Background: Mucous gland adenoma of the Bronchus is a rare benign epithelial tumor. The majority arises from the submucosal seromucous glands and ducts of the proximal airways. In Bronchus Biopsy specimen it might be difficult to distinguish mucous gland adenomas from low-grade malignant tumors, such as carcinoids, mucoepidermoid carcinomas, or adenoid cystic carcinomas. Complete tumor resection serves for both definite diagnosis and potential curative treatment. Case: A non smoking man of 78 years suffered from cough, dyspnea and recently from hemoptysis. Fiberoptic bronchoscopy revealed a polypoid, well-circumscribed mass in the right posterior segmental Bronchus. A bronchoscopic tumor excision was performed. Histology and immunohistochemistry (IHC): The tumor displayed with exuberant dilated cystic glands lined by columnar, cuboidal or flattened mucus secreting cells. IHC was positive for EMA, CKAE1/AE3, and negative for TTF1. Conclusion: Uncommon benign Bronchus adenomas should be taken into account in addition to the common malignant lung carcinomas with endobronchial growth pattern. Endoscopic tumor excision of Bronchus adenomas is indicated for potential curative treatment, especially in patients of higher age
-
mucous gland adenoma of a segment Bronchus case report
Diagnostic Pathology, 2015Co-Authors: Zaklina Zarko Mijovic, D Mihailovic, Nikola Zivkovic, Milos S Stankovic, Miloš KostovAbstract:BackgroundMucous gland adenoma of the Bronchus is a rare benign epithelial tumor. The majority arises from the submucosal seromucous glands and ducts of the proximal airways. In Bronchus Biopsy specimen it might be difficult to distinguish mucous gland adenomas from low-grade malignant tumors, such as carcinoids, mucoepidermoid carcinomas, or adenoid cystic carcinomas. Complete tumor resection serves for both definite diagnosis and potential curative treatment.CaseA non smoking man of 78 years suffered from cough, dyspnea and recently from hemoptysis. Fiberoptic bronchoscopy revealed a polypoid, well-circumscribed mass in the right posterior segmental Bronchus. A bronchoscopic tumor excision was performed.Histology and immunohistochemistry (IHC)The tumor displayed with exuberant dilated cystic glands lined by columnar, cuboidal or flattened mucus secreting cells. IHC was positive for EMA, CKAE1/AE3, and negative for TTF1.ConclusionUncommon benign Bronchus adenomas should be taken into account in addition to the common malignant lung carcinomas with endobronchial growth pattern. Endoscopic tumor excision of Bronchus adenomas is indicated for potential curative treatment, especially in patients of higher age.
J. Cunha - One of the best experts on this subject based on the ideXlab platform.
-
Endobronchial myxoma â Case report
Elsevier, 2012Co-Authors: R. Rolo, R. Pereira, R. Eisele, L. Ferreira, R. Nogueira, J. CunhaAbstract:Introduction: Pulmonary myxoma is an extremely rare benign neoplasm. It is mostly parenchymal but may occasionally occur within the tracheobronchial tree. There are very few reports of endobronchial myxoma. Case report: We describe a case of endobronchial myxoma in a 40-year-old female patient with a history of asthma and repeated right-sided pneumonia. Thoracic computed tomography (CT) showed medium lobe atelectasis. Fiber optic bronchoscopy revealed a polypoid, well-circumscribed tumor, causing total obstruction of the medium lobe Bronchus. Biopsy of the mass was non-diagnostic. Further study included a positron emission tomography (PET) which demonstrated low metabolic activity of the tumor and no evidence of neoplasia in other location. The patient was submitted to a medium lobectomy and microscopic examination of the tumor revealed myxoid stroma with lobulated pattern, elongated and stellate cells, compatible with myxoma. Conclusion: Pulmonary myxoma is extraordinary rare and endobronchial location is very few reported in medical literature. Resumo: Introdução: Os mixomas pulmonares são tumores benignos muito raros e quase sempre de localização parenquimatosa, mas ocasionalmente podem ocorrer na árvore traqueo-brônquica. Estão descritos raros casos de mixomas pulmonares endobrônquicos na literatura médica. Caso clÃnico: Doente do sexo feminino, de 40 anos, com história de asma e pneumonias de repetição à direita. A tomografia computadorizada (TC) do tórax revelou atelectasia do lobo médio. A broncofibroscopia revelou lesão tumoral polipóide, de limites bem definidos, causando obstrução total do brônquio lobar médio. A biopsia do tumor não foi diagnóstica. A tomografia por emissão de positrões (PET) demonstrou atividade metabólica baixa do tumor e ausência de evidência de malignidade noutros locais. A doente foi submetida a lobectomia média e o exame microscópico do tumor revelou um padrão lobular com células alongadas e estreladas, tipo fibroblasto, com estroma mixoide intercelular abundante, compatÃvel com mixoma pulmonar. Conclusão: O mixoma pulmonar é muito raro e a sua localização endobrônquica está descrita em poucos casos na literatura médica. Keywords: Pulmonary myxoma, Endobronchial, Rare tumor, Myxoid stroma, Palavras-chave: Mixoma pulmonar, Endobrônquico, Tumor raro, Estroma mixóid
-
Mixoma endobrônquico â Caso clÃnico
Elsevier, 2012Co-Authors: R. Rolo, R. Pereira, R. Eisele, L. Ferreira, R. Nogueira, J. CunhaAbstract:Resumo: Introdução: Os mixomas pulmonares são tumores benignos muito raros e quase sempre de localização parênquimatosa, mas ocasionalmente podem ocorrer na árvore traqueo-brônquica. Estão descritos raros casos de mixomas pulmonares endobrônquicos na literatura médica. Caso clÃnico: Doente do sexo feminino, de 40 anos, com história de asma e pneumonias de repetição à direita. A tomografia computadorizada (TC) do tórax revelou atelectasia do lobo médio. A broncofibroscopia revelou lesão tumoral polipóide, de limites bem definidos, causando obstrução total do brônquio lobar médio. A biopsia do tumor não foi diagnóstica. A tomografia por emissão de positrões (PET) demonstrou atividade metabólica baixa do tumor e ausência de evidência de malignidade noutros locais. A doente foi submetida a lobectomia média e o exame microscópico do tumor revelou um padrão lobular com células alongadas e estreladas, tipo fibroblasto, com estroma mixoide intercelular abundante, compatÃvel com mixoma pulmonar. Conclusão: O mixoma pulmonar é muito raro e a sua localização endobrônquica está descrita em poucos casos na literatura médica. Abstract: Introduction: Pulmonary myxoma is an extremely rare benign neoplasm. It is mostly parenchymal but may occasionally occur within the tracheobronchial tree. There are very few reports of endobronchial myxoma. Case report: We describe a case of endobronchial myxoma in a 40-year-old female patient with a history of asthma and repeated right-sided pneumonia. Thoracic computed tomography (CT) showed medium lobe atelectasis. Fiber optic bronchoscopy revealed a polypoid, well-circumscribed tumor, causing total obstruction of the medium lobe Bronchus. Biopsy of the mass was non-diagnostic. Further study included a positron emission tomography (PET) which demonstrated low metabolic activity of the tumor and no evidence of neoplasia in other location. The patient was submitted to a medium lobectomy and microscopic examination of the tumor revealed myxoid stroma with lobulated pattern, elongated and stellate cells, compatible with myxoma. Conclusion: Pulmonary myxoma is extraordinary rare and endobronchial location is very few reported in medical literature. Palavras-chave: Mixoma pulmonar, Endobrônquico, Tumor raro, Estroma mixóide, Keywords: Pulmonary myxoma, Endobronchial, Rare tumor, Myxoid strom
Zaklina Zarko Mijovic - One of the best experts on this subject based on the ideXlab platform.
-
mucous gland adenoma of a segment Bronchus case report
Diagnostic Pathology, 2015Co-Authors: Zaklina Zarko Mijovic, D Mihailovic, Nikola Zivkovic, Milos S Stankovic, Miloš KostovAbstract:BackgroundMucous gland adenoma of the Bronchus is a rare benign epithelial tumor. The majority arises from the submucosal seromucous glands and ducts of the proximal airways. In Bronchus Biopsy specimen it might be difficult to distinguish mucous gland adenomas from low-grade malignant tumors, such as carcinoids, mucoepidermoid carcinomas, or adenoid cystic carcinomas. Complete tumor resection serves for both definite diagnosis and potential curative treatment.CaseA non smoking man of 78 years suffered from cough, dyspnea and recently from hemoptysis. Fiberoptic bronchoscopy revealed a polypoid, well-circumscribed mass in the right posterior segmental Bronchus. A bronchoscopic tumor excision was performed.Histology and immunohistochemistry (IHC)The tumor displayed with exuberant dilated cystic glands lined by columnar, cuboidal or flattened mucus secreting cells. IHC was positive for EMA, CKAE1/AE3, and negative for TTF1.ConclusionUncommon benign Bronchus adenomas should be taken into account in addition to the common malignant lung carcinomas with endobronchial growth pattern. Endoscopic tumor excision of Bronchus adenomas is indicated for potential curative treatment, especially in patients of higher age.
R. Rolo - One of the best experts on this subject based on the ideXlab platform.
-
Endobronchial myxoma â Case report
Elsevier, 2012Co-Authors: R. Rolo, R. Pereira, R. Eisele, L. Ferreira, R. Nogueira, J. CunhaAbstract:Introduction: Pulmonary myxoma is an extremely rare benign neoplasm. It is mostly parenchymal but may occasionally occur within the tracheobronchial tree. There are very few reports of endobronchial myxoma. Case report: We describe a case of endobronchial myxoma in a 40-year-old female patient with a history of asthma and repeated right-sided pneumonia. Thoracic computed tomography (CT) showed medium lobe atelectasis. Fiber optic bronchoscopy revealed a polypoid, well-circumscribed tumor, causing total obstruction of the medium lobe Bronchus. Biopsy of the mass was non-diagnostic. Further study included a positron emission tomography (PET) which demonstrated low metabolic activity of the tumor and no evidence of neoplasia in other location. The patient was submitted to a medium lobectomy and microscopic examination of the tumor revealed myxoid stroma with lobulated pattern, elongated and stellate cells, compatible with myxoma. Conclusion: Pulmonary myxoma is extraordinary rare and endobronchial location is very few reported in medical literature. Resumo: Introdução: Os mixomas pulmonares são tumores benignos muito raros e quase sempre de localização parenquimatosa, mas ocasionalmente podem ocorrer na árvore traqueo-brônquica. Estão descritos raros casos de mixomas pulmonares endobrônquicos na literatura médica. Caso clÃnico: Doente do sexo feminino, de 40 anos, com história de asma e pneumonias de repetição à direita. A tomografia computadorizada (TC) do tórax revelou atelectasia do lobo médio. A broncofibroscopia revelou lesão tumoral polipóide, de limites bem definidos, causando obstrução total do brônquio lobar médio. A biopsia do tumor não foi diagnóstica. A tomografia por emissão de positrões (PET) demonstrou atividade metabólica baixa do tumor e ausência de evidência de malignidade noutros locais. A doente foi submetida a lobectomia média e o exame microscópico do tumor revelou um padrão lobular com células alongadas e estreladas, tipo fibroblasto, com estroma mixoide intercelular abundante, compatÃvel com mixoma pulmonar. Conclusão: O mixoma pulmonar é muito raro e a sua localização endobrônquica está descrita em poucos casos na literatura médica. Keywords: Pulmonary myxoma, Endobronchial, Rare tumor, Myxoid stroma, Palavras-chave: Mixoma pulmonar, Endobrônquico, Tumor raro, Estroma mixóid
-
Mixoma endobrônquico â Caso clÃnico
Elsevier, 2012Co-Authors: R. Rolo, R. Pereira, R. Eisele, L. Ferreira, R. Nogueira, J. CunhaAbstract:Resumo: Introdução: Os mixomas pulmonares são tumores benignos muito raros e quase sempre de localização parênquimatosa, mas ocasionalmente podem ocorrer na árvore traqueo-brônquica. Estão descritos raros casos de mixomas pulmonares endobrônquicos na literatura médica. Caso clÃnico: Doente do sexo feminino, de 40 anos, com história de asma e pneumonias de repetição à direita. A tomografia computadorizada (TC) do tórax revelou atelectasia do lobo médio. A broncofibroscopia revelou lesão tumoral polipóide, de limites bem definidos, causando obstrução total do brônquio lobar médio. A biopsia do tumor não foi diagnóstica. A tomografia por emissão de positrões (PET) demonstrou atividade metabólica baixa do tumor e ausência de evidência de malignidade noutros locais. A doente foi submetida a lobectomia média e o exame microscópico do tumor revelou um padrão lobular com células alongadas e estreladas, tipo fibroblasto, com estroma mixoide intercelular abundante, compatÃvel com mixoma pulmonar. Conclusão: O mixoma pulmonar é muito raro e a sua localização endobrônquica está descrita em poucos casos na literatura médica. Abstract: Introduction: Pulmonary myxoma is an extremely rare benign neoplasm. It is mostly parenchymal but may occasionally occur within the tracheobronchial tree. There are very few reports of endobronchial myxoma. Case report: We describe a case of endobronchial myxoma in a 40-year-old female patient with a history of asthma and repeated right-sided pneumonia. Thoracic computed tomography (CT) showed medium lobe atelectasis. Fiber optic bronchoscopy revealed a polypoid, well-circumscribed tumor, causing total obstruction of the medium lobe Bronchus. Biopsy of the mass was non-diagnostic. Further study included a positron emission tomography (PET) which demonstrated low metabolic activity of the tumor and no evidence of neoplasia in other location. The patient was submitted to a medium lobectomy and microscopic examination of the tumor revealed myxoid stroma with lobulated pattern, elongated and stellate cells, compatible with myxoma. Conclusion: Pulmonary myxoma is extraordinary rare and endobronchial location is very few reported in medical literature. Palavras-chave: Mixoma pulmonar, Endobrônquico, Tumor raro, Estroma mixóide, Keywords: Pulmonary myxoma, Endobronchial, Rare tumor, Myxoid strom
Milos S Stankovic - One of the best experts on this subject based on the ideXlab platform.
-
mucous gland adenoma of a segment Bronchus case report
Diagnostic Pathology, 2015Co-Authors: Zaklina Zarko Mijovic, D Mihailovic, Nikola Zivkovic, Milos S Stankovic, Miloš KostovAbstract:BackgroundMucous gland adenoma of the Bronchus is a rare benign epithelial tumor. The majority arises from the submucosal seromucous glands and ducts of the proximal airways. In Bronchus Biopsy specimen it might be difficult to distinguish mucous gland adenomas from low-grade malignant tumors, such as carcinoids, mucoepidermoid carcinomas, or adenoid cystic carcinomas. Complete tumor resection serves for both definite diagnosis and potential curative treatment.CaseA non smoking man of 78 years suffered from cough, dyspnea and recently from hemoptysis. Fiberoptic bronchoscopy revealed a polypoid, well-circumscribed mass in the right posterior segmental Bronchus. A bronchoscopic tumor excision was performed.Histology and immunohistochemistry (IHC)The tumor displayed with exuberant dilated cystic glands lined by columnar, cuboidal or flattened mucus secreting cells. IHC was positive for EMA, CKAE1/AE3, and negative for TTF1.ConclusionUncommon benign Bronchus adenomas should be taken into account in addition to the common malignant lung carcinomas with endobronchial growth pattern. Endoscopic tumor excision of Bronchus adenomas is indicated for potential curative treatment, especially in patients of higher age.
