vulvar pruritus and Burning Sensation in women with psoriasis

Approximately 80% of psoriatic individuals experience pruritus, of varying intensity. This study evaluated the frequency of vulvar itching and Burning and its influence on well-being in women with psoriasis. A total of 93 women were included in the study. Psoriasis severity was assessed according to the Psoriasis Area and Severity Index, the intensity of vulvar discomfort by visual analogue scale and depressive symptoms by Beck’s Depression Inventory. On admission 41 (44.1%) women experienced vulvar discomfort, 18 (19.4%) itching, 10 (10.8%) Burning and 13 (14.0%) both itching and Burning Sensations. Psoriatic lesions on the vulva were found in 22 (23.7%) women. No significant correlation was found between Burning or itching intensity and global psoriasis severity (r = 0.19, p = 0.26). Patients with vulvar discomfort had psoriatic lesions on the vulva more often than women without discomfort (43.6% vs. 8.2%, p < 0.001). In addition, patients with vulvar discomfort more frequently demonstrated depressive symptoms (p < 0.05). We conclude

recurrent facial erythema with Burning Sensation and increased temperature a variant of erythromelalgia or a new entity

Objective

Erythromelalgia is a rare clinical syndrome characterized by episodic attacks of Burning pain, erythema, and increased temperature, primarily affecting the extremities, and in rare instances, involving the ear, face, neck, and the scrotum. The dermatoscopic features of erythromelalgia in a case with solely facial involvement have never been described previously.

Observations

We describe a 14-year-old female who presented with erythema, Burning Sensation, and warmth on her face only, which mimic the features of erythromelalgia. Physical examination showed higher temperature on the involved cheeks than on axillas during the episode, while the temperature on both areas was the same between episodes. Dermatoscope showed more dilated vessels inside the erythema during the episodes than between the episodes. The symptoms had excellent response to the combination treatment of gabapentin, indomethacin, and topical lidocaine compounds.

Conclusions

The present case is considered to be a variant of erythromelalgia. Its erythema may be resulted from the dilated vessels. Combination of modalities may provide effective management for erythromelalgia. “Erythermalgia” may be better than “erythromelalgia” to describe such conditions.

heat Burning Sensation induced by topical application of capsaicin on perineal cutaneous area new approach in diagnosis and treatment of chronic prostatitis chronic pelvic pain syndrome

Abstract Objectives To investigate the feasibility, safety, and efficacy of perineal cutaneous application of capsaicin as a test for the diagnosis, as well as a potential therapeutic tool, in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods We recruited 22 patients (mean age 34.5 years, range 19 to 56), who had been diagnosed with CP/CPPS according to the National Institutes of Health criteria, and 6 healthy control subjects. Both groups received a topical application of 5 mL capsaicin at a concentration of 10 −5 M to the perineal body skin. The patients were asked to mark on a visual analogue scale the intensity of any heat or Burning Sensation. All the patients had completed a National Institutes of Health Chronic Prostatitis Symptom Index before and 1 week after the test. The scores of the two groups were compared using the Mann-Whitney U test. Results The patients with CP/CPPS reported a heat/Burning Sensation intensity that was statistically greater than that of the healthy controls (7.5 versus 4.3, P P P P Conclusions We found a statistically significant difference in the pain visual analogue scale and interval between topical application and the onset of the heat/Burning Sensation between patients with CP/CPPS and healthy controls. The small sample size strongly suggests the need for additional larger and more controlled studies.

Heat/Burning Sensation induced by topical application of capsaicin on perineal cutaneous area: new approach in diagnosis and treatment of chronic prostatitis/chronic pelvic pain syndrome?

Abstract Objectives To investigate the feasibility, safety, and efficacy of perineal cutaneous application of capsaicin as a test for the diagnosis, as well as a potential therapeutic tool, in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods We recruited 22 patients (mean age 34.5 years, range 19 to 56), who had been diagnosed with CP/CPPS according to the National Institutes of Health criteria, and 6 healthy control subjects. Both groups received a topical application of 5 mL capsaicin at a concentration of 10 −5 M to the perineal body skin. The patients were asked to mark on a visual analogue scale the intensity of any heat or Burning Sensation. All the patients had completed a National Institutes of Health Chronic Prostatitis Symptom Index before and 1 week after the test. The scores of the two groups were compared using the Mann-Whitney U test. Results The patients with CP/CPPS reported a heat/Burning Sensation intensity that was statistically greater than that of the healthy controls (7.5 versus 4.3, P P P P Conclusions We found a statistically significant difference in the pain visual analogue scale and interval between topical application and the onset of the heat/Burning Sensation between patients with CP/CPPS and healthy controls. The small sample size strongly suggests the need for additional larger and more controlled studies.