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H S Chandel - One of the best experts on this subject based on the ideXlab platform.
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evaluation of wound healing activity of acorus Calamus linn
Natural Product Research, 2010Co-Authors: Nilesh Jain, Ruchi Jain, Arti Jain, Deepak Kumar Jain, H S ChandelAbstract:The aim of the present study was to assess the wound-healing activity of ethanolic extracts of Acorus Calamus leaves. A wound was induced by an excision- and incision-based wound model in rats of either sex. The mature green leaves of A. Calamus were collected and authenticated. Extractions of dried leaves were carried out with 80% ethanol in a soxhlet apparatus. For wound-healing activity, the extracts were applied topically once daily in conc. of 40% w/w and 20% w/w in the form of ointment and compared with a standard drug (povidion-iodine). The healing of the wound was assessed by the rate of wound closure, period of epithelialisation, tensile strength and weight of the granulation tissue, hydroxyproline content and histopathology of the granulation tissue. The ethanolic extract of A. Calamus promoted wound-healing activity significantly in both the wound models studied. The histological study of the granulation tissue with 20% A. Calamus extract ointment-treated animals showed a larger number of infla...
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evaluation of wound healing activity of acorus Calamus linn
Natural Product Research, 2010Co-Authors: Nilesh Jain, Ruchi Jain, Arti Jain, Deepak Kumar Jain, H S ChandelAbstract:The aim of the present study was to assess the wound-healing activity of ethanolic extracts of Acorus Calamus leaves. A wound was induced by an excision- and incision-based wound model in rats of either sex. The mature green leaves of A. Calamus were collected and authenticated. Extractions of dried leaves were carried out with 80% ethanol in a soxhlet apparatus. For wound-healing activity, the extracts were applied topically once daily in conc. of 40% w/w and 20% w/w in the form of ointment and compared with a standard drug (povidion-iodine). The healing of the wound was assessed by the rate of wound closure, period of epithelialisation, tensile strength and weight of the granulation tissue, hydroxyproline content and histopathology of the granulation tissue. The ethanolic extract of A. Calamus promoted wound-healing activity significantly in both the wound models studied. The histological study of the granulation tissue with 20% A. Calamus extract ointment-treated animals showed a larger number of inflammatory cells and lesser collagen when compared with the 40% A. Calamus extract ointment-treated animals. However, this was better than the control group of animals. Enhanced wound contraction, decreased epithelialisation time, increased hydroxyproline content and histological characteristics suggest that A. Calamus extract may have therapeutic benefits in wound healing.
Nilesh Jain - One of the best experts on this subject based on the ideXlab platform.
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evaluation of wound healing activity of acorus Calamus linn
Natural Product Research, 2010Co-Authors: Nilesh Jain, Ruchi Jain, Arti Jain, Deepak Kumar Jain, H S ChandelAbstract:The aim of the present study was to assess the wound-healing activity of ethanolic extracts of Acorus Calamus leaves. A wound was induced by an excision- and incision-based wound model in rats of either sex. The mature green leaves of A. Calamus were collected and authenticated. Extractions of dried leaves were carried out with 80% ethanol in a soxhlet apparatus. For wound-healing activity, the extracts were applied topically once daily in conc. of 40% w/w and 20% w/w in the form of ointment and compared with a standard drug (povidion-iodine). The healing of the wound was assessed by the rate of wound closure, period of epithelialisation, tensile strength and weight of the granulation tissue, hydroxyproline content and histopathology of the granulation tissue. The ethanolic extract of A. Calamus promoted wound-healing activity significantly in both the wound models studied. The histological study of the granulation tissue with 20% A. Calamus extract ointment-treated animals showed a larger number of infla...
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evaluation of wound healing activity of acorus Calamus linn
Natural Product Research, 2010Co-Authors: Nilesh Jain, Ruchi Jain, Arti Jain, Deepak Kumar Jain, H S ChandelAbstract:The aim of the present study was to assess the wound-healing activity of ethanolic extracts of Acorus Calamus leaves. A wound was induced by an excision- and incision-based wound model in rats of either sex. The mature green leaves of A. Calamus were collected and authenticated. Extractions of dried leaves were carried out with 80% ethanol in a soxhlet apparatus. For wound-healing activity, the extracts were applied topically once daily in conc. of 40% w/w and 20% w/w in the form of ointment and compared with a standard drug (povidion-iodine). The healing of the wound was assessed by the rate of wound closure, period of epithelialisation, tensile strength and weight of the granulation tissue, hydroxyproline content and histopathology of the granulation tissue. The ethanolic extract of A. Calamus promoted wound-healing activity significantly in both the wound models studied. The histological study of the granulation tissue with 20% A. Calamus extract ointment-treated animals showed a larger number of inflammatory cells and lesser collagen when compared with the 40% A. Calamus extract ointment-treated animals. However, this was better than the control group of animals. Enhanced wound contraction, decreased epithelialisation time, increased hydroxyproline content and histological characteristics suggest that A. Calamus extract may have therapeutic benefits in wound healing.
Andrea Scorciapino - One of the best experts on this subject based on the ideXlab platform.
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chemical composition of the essential oil and supercritical co2 extract of commiphora myrrha nees engl and of acorus Calamus l
Journal of Agricultural and Food Chemistry, 2005Co-Authors: Bruno Marongiu, Alessandra Piras, Silvia Porcedda, Andrea ScorciapinoAbstract:Volatile concentrates from the oleo-gum resin of Commiphora myrrha (Nees) Engl. and from the rhizomes of Acorus Calamus were isolated by supercritical extraction with carbon dioxide. The volatile oil of myrrh was obtained at 9.0 MPa and 50 °C and at a CO2 flow of 1.5 kg/h. Acorus Calamus was extracted at 9.0 MPa and 45 °C and at a CO2 flow of 1.6 kg/h. In both cases, an oil devoid of cuticular waxes was obtained with a single depressurization stage. The SFE myrrh oil had a yield, Y, of 3.2%. Its main components, identified and quantified by GC/MS, were furanoeudesma-1,3-diene, 34.9%; lindestrene, 12.9%; curzerene, 8.5%; and germacrone, 5.8%. The essential oils from the same starting material by hydrodistillation, HD, (Y = 2.8%) and by steam distillation, SD, (Y = 0.4%) were quite similar to the SFE extract. The main components of the SFE oil of A. Calamus (Y = 3.5%) were acorenone, 13.4%; iso-acorone, 11.6%; (Z)-sesquilavandulol, 11.0%; dehydroxy isocalamendiol, 7.7%; and β-asarone, 5.5%. The comparison w...
Silalahi Marina - One of the best experts on this subject based on the ideXlab platform.
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SENYAWA BIOAKTIF PADA ACORUS Calamus (L.) DAN PEMANFAATANNYA SEBAGAI OBAT KANKER DAN ANTIMIKROBA
'UKI Press', 2018Co-Authors: Silalahi MarinaAbstract:ABSTRACT Jerango (Acorus Calamus L.) or also known as the sweet flag is a species in the Acoraceae which used as medicine. This article aims to reveal the relationship of secondary metabolites contained of the A. Calamus with its use as a cure for cancer and anti microbial. This article is based on offline and online media literature. Offline literature used the books, whereas online media used Web, Scopus, Pubmed, and scientific journals. Acorus Calamus is an aromatic plant containing the essential oils, especially asarone. The local community Indonesian has long been exploited the Acorus Calamus to cure fever, malnutrition, and postpartum mothers. The essential oil of the A. Calamus inhibits of microbial growth (bacteria, fungi and yeasts) and inhibits cell growth. The A. Calamus is potentially developed as a cancer drug, but its toxicity needs to be further investigated.Key Words: Acorus Calamus, asaron, anti cancer, anti microbial. ABSTRAK Jerango (Acorus Calamus L.) atau yang dikenal juga sebagai sweet flag merupakan salah jenis dalam famili Acoraceae yang dimanfaatkan sebagai obat. Artikel ini bertujuan untuk mengungkapkan hubungan metabolit sekunder yang dikandung A. Calamus denga pemanfaatannya sebagai obat kanker dan anti mikroba. This article is based on literature offline and online media. Offline literature used the books, whereas online media used Web, Scopus, Pubmed, and scientific journals. Acorus Calamus merupakan tumbuhan aromatik yang mengandung essensial oil, khususnya asaron. Masyarakat lokal Indonesia Acorus Calamus telah lama dimanfaatkan masyarakat lokal Indonesia sebagai obat demam, malnutrisi dan obat ibu pasca melahirkan. Essensial oil A. Calamus menghambat pertumbuhan mikroba (bakteri, jamur dan khamir) dan menghambat pertumbuhan sel. Acorus Calamus sangat potensial dikembangkan sebagai obat kanker, namun toksisitasnya perlu diteliti lebih lanjut.Kata Kunci: Acorus Calamus, asaron, anti kanker, anti mikrob
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Senyawa Bioaktif Pada Acorus Calamus (L.) Dan Pemanfaatannya Sebagai Obat Kanker Dan Antimikroba
Fakultas Keguruan dan Ilmu Pendidikan Universitas Kristen Indonesia, 2018Co-Authors: Silalahi MarinaAbstract:Jerango (Acorus Calamus L.) or also known as the sweet flag is a species in the Acoraceae which used as medicine. This article aims to reveal the relationship of secondary metabolites contained of the A. Calamus with its use as a cure for cancer and anti microbial. This article is based on offline and online media literature. Offline literature used the books, whereas online media used Web, Scopus, Pubmed, and scientific journals. Acorus Calamus is an aromatic plant containing the essential oils, especially asarone. The local community Indonesian has long been exploited the Acorus Calamus to cure fever, malnutrition, and postpartum mothers. The essential oil of the A. Calamus inhibits of microbial growth (bacteria, fungi and yeasts) and inhibits cell growth. The A. Calamus is potentially developed as a cancer drug, but its toxicity needs to be further investigated
Ruchi Jain - One of the best experts on this subject based on the ideXlab platform.
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evaluation of wound healing activity of acorus Calamus linn
Natural Product Research, 2010Co-Authors: Nilesh Jain, Ruchi Jain, Arti Jain, Deepak Kumar Jain, H S ChandelAbstract:The aim of the present study was to assess the wound-healing activity of ethanolic extracts of Acorus Calamus leaves. A wound was induced by an excision- and incision-based wound model in rats of either sex. The mature green leaves of A. Calamus were collected and authenticated. Extractions of dried leaves were carried out with 80% ethanol in a soxhlet apparatus. For wound-healing activity, the extracts were applied topically once daily in conc. of 40% w/w and 20% w/w in the form of ointment and compared with a standard drug (povidion-iodine). The healing of the wound was assessed by the rate of wound closure, period of epithelialisation, tensile strength and weight of the granulation tissue, hydroxyproline content and histopathology of the granulation tissue. The ethanolic extract of A. Calamus promoted wound-healing activity significantly in both the wound models studied. The histological study of the granulation tissue with 20% A. Calamus extract ointment-treated animals showed a larger number of infla...
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evaluation of wound healing activity of acorus Calamus linn
Natural Product Research, 2010Co-Authors: Nilesh Jain, Ruchi Jain, Arti Jain, Deepak Kumar Jain, H S ChandelAbstract:The aim of the present study was to assess the wound-healing activity of ethanolic extracts of Acorus Calamus leaves. A wound was induced by an excision- and incision-based wound model in rats of either sex. The mature green leaves of A. Calamus were collected and authenticated. Extractions of dried leaves were carried out with 80% ethanol in a soxhlet apparatus. For wound-healing activity, the extracts were applied topically once daily in conc. of 40% w/w and 20% w/w in the form of ointment and compared with a standard drug (povidion-iodine). The healing of the wound was assessed by the rate of wound closure, period of epithelialisation, tensile strength and weight of the granulation tissue, hydroxyproline content and histopathology of the granulation tissue. The ethanolic extract of A. Calamus promoted wound-healing activity significantly in both the wound models studied. The histological study of the granulation tissue with 20% A. Calamus extract ointment-treated animals showed a larger number of inflammatory cells and lesser collagen when compared with the 40% A. Calamus extract ointment-treated animals. However, this was better than the control group of animals. Enhanced wound contraction, decreased epithelialisation time, increased hydroxyproline content and histological characteristics suggest that A. Calamus extract may have therapeutic benefits in wound healing.