The Experts below are selected from a list of 6183 Experts worldwide ranked by ideXlab platform
Rick W Wright - One of the best experts on this subject based on the ideXlab platform.
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Calcium Pyrophosphate dihydrate deposition disease pseudogout after total knee arthroplasty
Journal of Arthroplasty, 2007Co-Authors: Christopher B Hirose, Rick W WrightAbstract:The authors report a case of Calcium Pyrophosphate dihydrate deposition disease (pseudogout) presenting in the early period after primary total knee arthroplasty. The patient's symptoms resolved with conservative management including colchicine and indomethacin. The presentation of pseudogout resembles septic arthritis and should be included in the differential diagnosis to prevent unnecessary surgery in these patients.
Michael Salcman - One of the best experts on this subject based on the ideXlab platform.
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Calcium Pyrophosphate Arthropathy of the Spine
Neurosurgery, 1994Co-Authors: Michael Salcman, Agha Khan, Daniel A. SymondsAbstract:Calcium Pyrophosphate deposition disease is a relatively uncommon arthropathy characterized by the clinical features of pseudogout, the radiographic manifestations of chondrocalcinosis, and the pathological deposition of Calcium Pyrophosphate crystals in both hyaline and fibrocartilage. Symptomatic involvement of the spine by Calcium Pyrophosphate deposition disease is rare except by nodular deposition in the ligamentum flavum and atlanto-occipital ligament. We report a 50-year-old woman who presented with an acute herniated disc syndrome secondary to an intraspinal inflammatory Calcium Pyrophosphate deposition disease mass at the level of the L4-L5 interspace. The magnetic resonance image and histopathological features of the case are also discussed.
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Calcium Pyrophosphate arthropathy of the spine case report and review of the literature
Neurosurgery, 1994Co-Authors: Michael Salcman, Agha Khan, Daniel A. SymondsAbstract:Calcium Pyrophosphate deposition disease is a relatively uncommon arthropathy characterized by the clinical features of pseudogout, the radiographic manifestations of chondrocalcinosis, and the pathological deposition of Calcium Pyrophosphate crystals in both hyaline and fibrocartilage. Symptomatic involvement of the spine by Calcium Pyrophosphate deposition disease is rare except by nodular deposition in the ligamentum flavum and atlanto-occipital ligament. We report a 50-year-old woman who presented with an acute herniated disc syndrome secondary to an intraspinal inflammatory Calcium Pyrophosphate deposition disease mass at the level of the L4-L5 interspace. The magnetic resonance image and histopathological features of the case are also discussed.
Christopher B Hirose - One of the best experts on this subject based on the ideXlab platform.
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Calcium Pyrophosphate dihydrate deposition disease pseudogout after total knee arthroplasty
Journal of Arthroplasty, 2007Co-Authors: Christopher B Hirose, Rick W WrightAbstract:The authors report a case of Calcium Pyrophosphate dihydrate deposition disease (pseudogout) presenting in the early period after primary total knee arthroplasty. The patient's symptoms resolved with conservative management including colchicine and indomethacin. The presentation of pseudogout resembles septic arthritis and should be included in the differential diagnosis to prevent unnecessary surgery in these patients.
Ann K. Rosenthal - One of the best experts on this subject based on the ideXlab platform.
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The Role of ANK in Calcium Pyrophosphate Deposition Disease
Current Rheumatology Reports, 2016Co-Authors: Elizabeth Mitton-fitzgerald, Claudia M. Gohr, Brittany Bettendorf, Ann K. RosenthalAbstract:The protein product of the progressive ankylosis gene, known as ANK, is a 492-amino acid multi-pass transmembrane protein. This protein is critical for the regulation of Pyrophosphate, and gain of function ANK mutations is associated with Calcium Pyrophosphate deposition disease. Much about the structure, function, and regulation of ANK remain unstudied. This review of the current literature examines recent contributions to our understanding of ANK. We focus on new work on the function, binding partners, and regulators of ANK. A more complete understanding of this important protein may help to identify future therapeutic targets for the treatment of Calcium Pyrophosphate deposition disease.
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validation of administrative codes for Calcium Pyrophosphate deposition a veterans administration study
Jcr-journal of Clinical Rheumatology, 2015Co-Authors: Christie M Bartels, Jasvinder A Singh, Konstantinos Parperis, Karri Huber, Ann K. RosenthalAbstract:BackgroundDespite high prevalence, progress in Calcium Pyrophosphate deposition (CPPD) has been limited by poor awareness and absence of validated approaches to study it in large data sets.ObjectivesWe aimed to determine the accuracy of administrative codes for the diagnosis of CPPD as a foundationa
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Imaging of Calcium Pyrophosphate Deposition Disease
Current Rheumatology Reports, 2015Co-Authors: Jennifer Miksanek, Ann K. RosenthalAbstract:Calcium Pyrophosphate deposition disease (CPPD) is a common and clinically heterogeneous form of arthritis caused by the deposition of Calcium Pyrophosphate (CPP) crystals in articular tissues. The diagnosis of CPPD is supported by the presence of radiographic chondrocalcinosis; yet, conventional radiography detects only about 40 % of clinically important CPPD. Here, we critically review the recent literature on imaging in CPPD. New studies inform our use of conventional radiographic screening methodologies for CPPD and provide additional evidence for the utility of diagnostic ultrasound. Recent work also highlights the polyarticular nature of CPPD, its association with tissue damage, and the high prevalence of tendon involvement. While dual energy CT and diffraction-enhanced synchrotron imaging remain research tools, they present potential avenues for improved visualization of CPP deposits. Advances in imaging in CPPD will increase diagnostic accuracy and eventually result in better management of this common form of arthritis.
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Pathogenesis of Calcium Pyrophosphate crystal deposition disease
Current Rheumatology Reports, 2001Co-Authors: Ann K. RosenthalAbstract:Calcium Pyrophosphate dihydrate deposition (CPPDD) disease is an increasingly common form of arthritis affecting the elderly. It is characterized by the formation of CPPD crystals in articular cartilage and usually results in severe cartilage destruction with loss of joint function. This article discusses our understanding of how and why these crystals form, highlighting recent developments in the field.
Daniel A. Symonds - One of the best experts on this subject based on the ideXlab platform.
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Calcium Pyrophosphate Arthropathy of the Spine
Neurosurgery, 1994Co-Authors: Michael Salcman, Agha Khan, Daniel A. SymondsAbstract:Calcium Pyrophosphate deposition disease is a relatively uncommon arthropathy characterized by the clinical features of pseudogout, the radiographic manifestations of chondrocalcinosis, and the pathological deposition of Calcium Pyrophosphate crystals in both hyaline and fibrocartilage. Symptomatic involvement of the spine by Calcium Pyrophosphate deposition disease is rare except by nodular deposition in the ligamentum flavum and atlanto-occipital ligament. We report a 50-year-old woman who presented with an acute herniated disc syndrome secondary to an intraspinal inflammatory Calcium Pyrophosphate deposition disease mass at the level of the L4-L5 interspace. The magnetic resonance image and histopathological features of the case are also discussed.
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Calcium Pyrophosphate arthropathy of the spine case report and review of the literature
Neurosurgery, 1994Co-Authors: Michael Salcman, Agha Khan, Daniel A. SymondsAbstract:Calcium Pyrophosphate deposition disease is a relatively uncommon arthropathy characterized by the clinical features of pseudogout, the radiographic manifestations of chondrocalcinosis, and the pathological deposition of Calcium Pyrophosphate crystals in both hyaline and fibrocartilage. Symptomatic involvement of the spine by Calcium Pyrophosphate deposition disease is rare except by nodular deposition in the ligamentum flavum and atlanto-occipital ligament. We report a 50-year-old woman who presented with an acute herniated disc syndrome secondary to an intraspinal inflammatory Calcium Pyrophosphate deposition disease mass at the level of the L4-L5 interspace. The magnetic resonance image and histopathological features of the case are also discussed.
