The Experts below are selected from a list of 21618 Experts worldwide ranked by ideXlab platform
Warwick Bruce - One of the best experts on this subject based on the ideXlab platform.
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response of a Calcium Sulfate bone graft substitute in a confined cancellous defect
Clinical Orthopaedics and Related Research, 2003Co-Authors: William R Walsh, P Morberg, Yan Yu, Jialin Yang, W Haggard, P C Sheath, M Svehla, Warwick BruceAbstract:Calcium Sulfate, plaster of Paris, has a long clinical history for use as a bone graft substitute in various skeletal sites. The current authors examined the in vivo response of Calcium Sulfate pellets alone or in combination with autogenous bone graft in a bilateral critical-size distal femoral cancellous defect in an adult sheep model. New thick bone formation was seen in defects filled with Calcium Sulfate pellets alone. Increased immunostaining for bone morphogenetic protein-2, bone morphogenetic protein-7, transforming growth factor-β, and platelet derived growth factor was seen in defects filled with Calcium Sulfate pellets alone and in combination with autograft. The local acidity during Calcium Sulfate resorption is proposed as a possible in vivo mechanism for this type of material.
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Response of a Calcium Sulfate bone graft substitute in a confined cancellous defect.
Clinical orthopaedics and related research, 2003Co-Authors: William R Walsh, P Morberg, Jialin Yang, W Haggard, P C Sheath, M Svehla, Warwick BruceAbstract:Calcium Sulfate, plaster of Paris, has a long clinical history for use as a bone graft substitute in various skeletal sites. The current authors examined the in vivo response of Calcium Sulfate pellets alone or in combination with autogenous bone graft in a bilateral critical-size distal femoral cancellous defect in an adult sheep model. New thick bone formation was seen in defects filled with Calcium Sulfate pellets alone. Increased immunostaining for bone morphogenetic protein-2, bone morphogenetic protein-7, transforming growth factor-beta, and platelet derived growth factor was seen in defects filled with Calcium Sulfate pellets alone and in combination with autograft. The local acidity during Calcium Sulfate resorption is proposed as a possible in vivo mechanism for this type of material.
Arnaud Perrot - One of the best experts on this subject based on the ideXlab platform.
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Rheological properties of Calcium Sulfate suspensions
Cement and Concrete Research, 2015Co-Authors: Alexandre Pierre, Christophe Lanos, Patrice Estellé, Arnaud PerrotAbstract:The rheological properties of Calcium Sulfate anhydrite particles dispersed in water are studied in the presence of two polycarboxylate superplasticizers. Gel permeation chromatography is used to investigate the molecular structure of the superplasticizers. Rheological shear flow measurements are carried out to investigate the effect of the two polycarboxylate superplasticizers as well as the solid volume fraction on the elastic moduli and yield stress of Calcium Sulfate suspensions. The affinity of polymers with Calcium Sulfate particles is characterized by the determination of Total Organic Carbon contents. A link is highlighted between the rheological behaviour of the suspensions, the adsorption onto mineral particles and the molecular weight of the superplasticizers. Particular attention is taken to compute the interparticle distance in the suspension as a function of the solid volume fraction and the amount of superplasticizer. For this purpose, a model based on mechanical and homogenization assumptions is developed to compute a thickness ratio of the adsorbed polymer layer. Results from the proposed model suggest that the interparticle distance is dependent on the solid volume fraction and the mix-proportion of polymer.
William R Walsh - One of the best experts on this subject based on the ideXlab platform.
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response of a Calcium Sulfate bone graft substitute in a confined cancellous defect
Clinical Orthopaedics and Related Research, 2003Co-Authors: William R Walsh, P Morberg, Yan Yu, Jialin Yang, W Haggard, P C Sheath, M Svehla, Warwick BruceAbstract:Calcium Sulfate, plaster of Paris, has a long clinical history for use as a bone graft substitute in various skeletal sites. The current authors examined the in vivo response of Calcium Sulfate pellets alone or in combination with autogenous bone graft in a bilateral critical-size distal femoral cancellous defect in an adult sheep model. New thick bone formation was seen in defects filled with Calcium Sulfate pellets alone. Increased immunostaining for bone morphogenetic protein-2, bone morphogenetic protein-7, transforming growth factor-β, and platelet derived growth factor was seen in defects filled with Calcium Sulfate pellets alone and in combination with autograft. The local acidity during Calcium Sulfate resorption is proposed as a possible in vivo mechanism for this type of material.
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Response of a Calcium Sulfate bone graft substitute in a confined cancellous defect.
Clinical orthopaedics and related research, 2003Co-Authors: William R Walsh, P Morberg, Jialin Yang, W Haggard, P C Sheath, M Svehla, Warwick BruceAbstract:Calcium Sulfate, plaster of Paris, has a long clinical history for use as a bone graft substitute in various skeletal sites. The current authors examined the in vivo response of Calcium Sulfate pellets alone or in combination with autogenous bone graft in a bilateral critical-size distal femoral cancellous defect in an adult sheep model. New thick bone formation was seen in defects filled with Calcium Sulfate pellets alone. Increased immunostaining for bone morphogenetic protein-2, bone morphogenetic protein-7, transforming growth factor-beta, and platelet derived growth factor was seen in defects filled with Calcium Sulfate pellets alone and in combination with autograft. The local acidity during Calcium Sulfate resorption is proposed as a possible in vivo mechanism for this type of material.
Baohong Guan - One of the best experts on this subject based on the ideXlab platform.
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Structural evolution of amorphous Calcium Sulfate nanoparticles into crystalline gypsum phase
CrystEngComm, 2020Co-Authors: Caiyun Jia, Qiaoshan Chen, James J. De Yoreo, Baohong GuanAbstract:The involvement of amorphous Calcium Sulfate (ACS) as a precursor to Calcium Sulfate crystallization remains an important but poorly understood phenomenon, especially the mechanism by which ACS evolves into crystalline phase. Here, we captured the ACS nanoparticles as a precursor to Calcium Sulfate crystallization in a concentrated CaCl2 solution at 90 °C and observed several stages of its evolution. The ACS nanoparticles grew by simultaneous fusion and internal structural evolution. Aggregation of the ACS nanoparticles gave birth to bulk ACS particles within which nanocrystalline domains sprouted and developed into crystalline gypsum. This work deepens the understanding of the evolution of ACS nanoparticles and its role in multistage crystallization of Calcium Sulfate.
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Formation of mesoporous Calcium Sulfate microspheres through phase conversion in controlled calcination
RSC Advances, 2016Co-Authors: Qiaoshan Chen, Guangming Jiang, Mengqian Qian, Caiyun Jia, Junming Lin, Baohong GuanAbstract:Calcium Sulfate has been used as a biomedical material for over a century thanks to its biocompatible, biodegradable and cementitious properties. However the dense structure and low surface area of existing materials exclude its adsorption properties and restrict the applications. In this work, mesoporous Calcium Sulfate microspheres are prepared through topological conversion of monodisperse α-Calcium Sulfate hemihydrate (α-HH) microspheres under controlled calcination. The calcination process contributes to the phase conversion from α-HH to Calcium Sulfate anhydrite (AH) along with the elimination of structural water and the reduction of crystallite size, resulting in the formation of mesopores. The microspheres composed of 29.56 wt% α-HH and 70.44 wt% AH demonstrate a maximum surface area of 30.62 m2 g−1 and an ibuprofen (IBU) loading capacity of 22.44 mg g−1, which shows a one hundred times improvement in surface area compared with traditional Calcium Sulfate materials. This is the first time drugs have been loaded directly to Calcium Sulfate particles, showing that the mesoporous Calcium Sulfate microspheres with uniform particle size and ordered pore structure could be a promising carrier as a biomaterial.
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solution mediated transformation kinetics of Calcium Sulfate dihydrate to α Calcium Sulfate hemihydrate in cacl2 solutions at elevated temperature
Industrial & Engineering Chemistry Research, 2013Co-Authors: Guangming Jiang, Hao Wang, Baohong GuanAbstract:α-Calcium Sulfate hemihydrate (α-HH), a kind of advanced cementitious material, can be prepared from Calcium Sulfate dihydrate (DH) in electrolyte solutions. The kinetics of the DH−α-HH transformat...
Alexandre Pierre - One of the best experts on this subject based on the ideXlab platform.
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Rheological properties of Calcium Sulfate suspensions
Cement and Concrete Research, 2015Co-Authors: Alexandre Pierre, Christophe Lanos, Patrice Estellé, Arnaud PerrotAbstract:The rheological properties of Calcium Sulfate anhydrite particles dispersed in water are studied in the presence of two polycarboxylate superplasticizers. Gel permeation chromatography is used to investigate the molecular structure of the superplasticizers. Rheological shear flow measurements are carried out to investigate the effect of the two polycarboxylate superplasticizers as well as the solid volume fraction on the elastic moduli and yield stress of Calcium Sulfate suspensions. The affinity of polymers with Calcium Sulfate particles is characterized by the determination of Total Organic Carbon contents. A link is highlighted between the rheological behaviour of the suspensions, the adsorption onto mineral particles and the molecular weight of the superplasticizers. Particular attention is taken to compute the interparticle distance in the suspension as a function of the solid volume fraction and the amount of superplasticizer. For this purpose, a model based on mechanical and homogenization assumptions is developed to compute a thickness ratio of the adsorbed polymer layer. Results from the proposed model suggest that the interparticle distance is dependent on the solid volume fraction and the mix-proportion of polymer.
