The Experts below are selected from a list of 2967 Experts worldwide ranked by ideXlab platform

Keshava Rajagopal - One of the best experts on this subject based on the ideXlab platform.

  • determination of pressure data from velocity data with a view towards its application in Cardiovascular Mechanics part 2 a study of aortic valve stenosis
    International Journal of Engineering Science, 2017
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract This paper is Part 2 of a study of blood flow across Cardiovascular stenoses. In Part 1, we developed a rigorous mathematical approach for deriving a pressure field from experimental data for a velocity field that can be obtained by direct measurement. In this Part, existing methods for quantifying stenoses, with specific reference to cardiac valves, are reviewed. Using the mathematically rigorous and physically reasonable approach that we developed in Part 1, for a pre-specified flow velocity field proximal to the stenosis and pressure waveform field distal to the stenosis, we ascertain the intra-stenosis and distal flow velocity field, pressure field proximal to and within the stenosis, and energy dissipation, all as functions of position and time. The computed dissipation, kinetic energy and pressure are then presented in an idealized geometry, but relevant to a realistic geometry, with a symmetric stenosis.

  • determination of pressure data from velocity data with a view toward its application in Cardiovascular Mechanics part 1 theoretical considerations
    International Journal of Engineering Science, 2016
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract The non-invasive determination of the pressure (mean normal stress) in a flowing fluid has ramifications in a variety of important problems: the flow of blood in blood vessels, flows taking place in inaccessible locations in complex internal geometries that occur in mechanical systems, etc. In this paper we discuss a rigorous new mathematical procedure for the determination of the pressure (mean normal stress) field, from data for the velocity field that can be obtained through imaging procedures such as 4D magnetic resonance imaging or echocardiography. We then use the procedure to demonstrate its efficacy by considering flows in an idealized geometry with a symmetric and asymmetric obstruction. We delineate the superiority of the method with regard to the methods that are currently in place. In Part 2 of this two part paper, we study the loss of pressure and the dissipation that occurs due to the flow of blood across a diseased valve (the pressure loss being an important indicator of the extent of the valvular disease) as well as the flow taking place in a realistic cerebral aneurysm.

Helena Svihlova - One of the best experts on this subject based on the ideXlab platform.

  • determination of pressure data from velocity data with a view towards its application in Cardiovascular Mechanics part 2 a study of aortic valve stenosis
    International Journal of Engineering Science, 2017
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract This paper is Part 2 of a study of blood flow across Cardiovascular stenoses. In Part 1, we developed a rigorous mathematical approach for deriving a pressure field from experimental data for a velocity field that can be obtained by direct measurement. In this Part, existing methods for quantifying stenoses, with specific reference to cardiac valves, are reviewed. Using the mathematically rigorous and physically reasonable approach that we developed in Part 1, for a pre-specified flow velocity field proximal to the stenosis and pressure waveform field distal to the stenosis, we ascertain the intra-stenosis and distal flow velocity field, pressure field proximal to and within the stenosis, and energy dissipation, all as functions of position and time. The computed dissipation, kinetic energy and pressure are then presented in an idealized geometry, but relevant to a realistic geometry, with a symmetric stenosis.

  • determination of pressure data from velocity data with a view toward its application in Cardiovascular Mechanics part 1 theoretical considerations
    International Journal of Engineering Science, 2016
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract The non-invasive determination of the pressure (mean normal stress) in a flowing fluid has ramifications in a variety of important problems: the flow of blood in blood vessels, flows taking place in inaccessible locations in complex internal geometries that occur in mechanical systems, etc. In this paper we discuss a rigorous new mathematical procedure for the determination of the pressure (mean normal stress) field, from data for the velocity field that can be obtained through imaging procedures such as 4D magnetic resonance imaging or echocardiography. We then use the procedure to demonstrate its efficacy by considering flows in an idealized geometry with a symmetric and asymmetric obstruction. We delineate the superiority of the method with regard to the methods that are currently in place. In Part 2 of this two part paper, we study the loss of pressure and the dissipation that occurs due to the flow of blood across a diseased valve (the pressure loss being an important indicator of the extent of the valvular disease) as well as the flow taking place in a realistic cerebral aneurysm.

Josef Malek - One of the best experts on this subject based on the ideXlab platform.

  • determination of pressure data from velocity data with a view towards its application in Cardiovascular Mechanics part 2 a study of aortic valve stenosis
    International Journal of Engineering Science, 2017
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract This paper is Part 2 of a study of blood flow across Cardiovascular stenoses. In Part 1, we developed a rigorous mathematical approach for deriving a pressure field from experimental data for a velocity field that can be obtained by direct measurement. In this Part, existing methods for quantifying stenoses, with specific reference to cardiac valves, are reviewed. Using the mathematically rigorous and physically reasonable approach that we developed in Part 1, for a pre-specified flow velocity field proximal to the stenosis and pressure waveform field distal to the stenosis, we ascertain the intra-stenosis and distal flow velocity field, pressure field proximal to and within the stenosis, and energy dissipation, all as functions of position and time. The computed dissipation, kinetic energy and pressure are then presented in an idealized geometry, but relevant to a realistic geometry, with a symmetric stenosis.

  • determination of pressure data from velocity data with a view toward its application in Cardiovascular Mechanics part 1 theoretical considerations
    International Journal of Engineering Science, 2016
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract The non-invasive determination of the pressure (mean normal stress) in a flowing fluid has ramifications in a variety of important problems: the flow of blood in blood vessels, flows taking place in inaccessible locations in complex internal geometries that occur in mechanical systems, etc. In this paper we discuss a rigorous new mathematical procedure for the determination of the pressure (mean normal stress) field, from data for the velocity field that can be obtained through imaging procedures such as 4D magnetic resonance imaging or echocardiography. We then use the procedure to demonstrate its efficacy by considering flows in an idealized geometry with a symmetric and asymmetric obstruction. We delineate the superiority of the method with regard to the methods that are currently in place. In Part 2 of this two part paper, we study the loss of pressure and the dissipation that occurs due to the flow of blood across a diseased valve (the pressure loss being an important indicator of the extent of the valvular disease) as well as the flow taking place in a realistic cerebral aneurysm.

K R Rajagopal - One of the best experts on this subject based on the ideXlab platform.

  • determination of pressure data from velocity data with a view towards its application in Cardiovascular Mechanics part 2 a study of aortic valve stenosis
    International Journal of Engineering Science, 2017
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract This paper is Part 2 of a study of blood flow across Cardiovascular stenoses. In Part 1, we developed a rigorous mathematical approach for deriving a pressure field from experimental data for a velocity field that can be obtained by direct measurement. In this Part, existing methods for quantifying stenoses, with specific reference to cardiac valves, are reviewed. Using the mathematically rigorous and physically reasonable approach that we developed in Part 1, for a pre-specified flow velocity field proximal to the stenosis and pressure waveform field distal to the stenosis, we ascertain the intra-stenosis and distal flow velocity field, pressure field proximal to and within the stenosis, and energy dissipation, all as functions of position and time. The computed dissipation, kinetic energy and pressure are then presented in an idealized geometry, but relevant to a realistic geometry, with a symmetric stenosis.

  • determination of pressure data from velocity data with a view toward its application in Cardiovascular Mechanics part 1 theoretical considerations
    International Journal of Engineering Science, 2016
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract The non-invasive determination of the pressure (mean normal stress) in a flowing fluid has ramifications in a variety of important problems: the flow of blood in blood vessels, flows taking place in inaccessible locations in complex internal geometries that occur in mechanical systems, etc. In this paper we discuss a rigorous new mathematical procedure for the determination of the pressure (mean normal stress) field, from data for the velocity field that can be obtained through imaging procedures such as 4D magnetic resonance imaging or echocardiography. We then use the procedure to demonstrate its efficacy by considering flows in an idealized geometry with a symmetric and asymmetric obstruction. We delineate the superiority of the method with regard to the methods that are currently in place. In Part 2 of this two part paper, we study the loss of pressure and the dissipation that occurs due to the flow of blood across a diseased valve (the pressure loss being an important indicator of the extent of the valvular disease) as well as the flow taking place in a realistic cerebral aneurysm.

Jaroslav Hron - One of the best experts on this subject based on the ideXlab platform.

  • determination of pressure data from velocity data with a view towards its application in Cardiovascular Mechanics part 2 a study of aortic valve stenosis
    International Journal of Engineering Science, 2017
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract This paper is Part 2 of a study of blood flow across Cardiovascular stenoses. In Part 1, we developed a rigorous mathematical approach for deriving a pressure field from experimental data for a velocity field that can be obtained by direct measurement. In this Part, existing methods for quantifying stenoses, with specific reference to cardiac valves, are reviewed. Using the mathematically rigorous and physically reasonable approach that we developed in Part 1, for a pre-specified flow velocity field proximal to the stenosis and pressure waveform field distal to the stenosis, we ascertain the intra-stenosis and distal flow velocity field, pressure field proximal to and within the stenosis, and energy dissipation, all as functions of position and time. The computed dissipation, kinetic energy and pressure are then presented in an idealized geometry, but relevant to a realistic geometry, with a symmetric stenosis.

  • determination of pressure data from velocity data with a view toward its application in Cardiovascular Mechanics part 1 theoretical considerations
    International Journal of Engineering Science, 2016
    Co-Authors: Helena Svihlova, Jaroslav Hron, Josef Malek, K R Rajagopal, Keshava Rajagopal
    Abstract:

    Abstract The non-invasive determination of the pressure (mean normal stress) in a flowing fluid has ramifications in a variety of important problems: the flow of blood in blood vessels, flows taking place in inaccessible locations in complex internal geometries that occur in mechanical systems, etc. In this paper we discuss a rigorous new mathematical procedure for the determination of the pressure (mean normal stress) field, from data for the velocity field that can be obtained through imaging procedures such as 4D magnetic resonance imaging or echocardiography. We then use the procedure to demonstrate its efficacy by considering flows in an idealized geometry with a symmetric and asymmetric obstruction. We delineate the superiority of the method with regard to the methods that are currently in place. In Part 2 of this two part paper, we study the loss of pressure and the dissipation that occurs due to the flow of blood across a diseased valve (the pressure loss being an important indicator of the extent of the valvular disease) as well as the flow taking place in a realistic cerebral aneurysm.