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K S Kristensen - One of the best experts on this subject based on the ideXlab platform.
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White coat hypertension is a Cardiovascular Risk Factor: a 10-year follow-up study
Journal of Human Hypertension, 2003Co-Authors: P H Gustavsen, A Høegholm, L E Bang, K S KristensenAbstract:The objective of this paper was to evaluate the Cardiovascular Risk in white coat hypertension (WCH). WCH is a well-known clinical entity defined by persistently elevated blood pressure (BP) in the doctor's office, whereas BP in other conditions is normal. The prognosis of WCH is unsettled, although two prospective studies that include normal control groups imply that the condition is benign. This study is a 10-year follow-up study on 420 patients with grade I–II hypertension newly diagnosed by their general practitioner and 146 normal controls (NTs). Ambulatory blood pressure (ABP) monitoring was performed at baseline. With our protocollated cutoff value of daytime-ABP
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white coat hypertension is a Cardiovascular Risk Factor a 10 year follow up study
Journal of Human Hypertension, 2003Co-Authors: P H Gustavsen, A Høegholm, L E Bang, K S KristensenAbstract:The objective of this paper was to evaluate the Cardiovascular Risk in white coat hypertension (WCH). WCH is a well-known clinical entity defined by persistently elevated blood pressure (BP) in the doctor's office, whereas BP in other conditions is normal. The prognosis of WCH is unsettled, although two prospective studies that include normal control groups imply that the condition is benign. This study is a 10-year follow-up study on 420 patients with grade I–II hypertension newly diagnosed by their general practitioner and 146 normal controls (NTs). Ambulatory blood pressure (ABP) monitoring was performed at baseline. With our protocollated cutoff value of daytime-ABP <135/90 mmHg, 76 (18.1%) of the 420 hypertensives were white coat hypertensives (WCHs) and 344 were established hypertensives (EHs). With a lower cutoff of 135/85 mmHg, 40 (9.5%) were WCHs. Complete follow-up data were obtained for all 566 subjects. The mean duration of follow-up was 10.2 years (range 9.0–12.5). In the WCH group, 14 first events were recorded (18.4%) consisting of two Cardiovascular deaths and 12 nonfatal Cardiovascular events. In the EH group, the corresponding number of events were 56 first events (16.3%), 12 Cardiovascular deaths and 44 nonfatal Cardiovascular events, and in the NT group 10 first events (6.8%), two Cardiovascular deaths and eight nonfatal Cardiovascular events. The event rate was similar in the WCH group and the EH group and significantly lower in the NT group (P<0.05). When corrected for daytime-ABP, age and other confounders, the difference remained statistically significant. When using the lower cutoff of 135/85 mmHg, WCH was still associated with a significantly higher Cardiovascular event rate. In conclusion, the main finding of this 10-year follow-up study is an increased Cardiovascular Risk in WCH compared to normotensive controls.
P H Gustavsen - One of the best experts on this subject based on the ideXlab platform.
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White coat hypertension is a Cardiovascular Risk Factor: a 10-year follow-up study
Journal of Human Hypertension, 2003Co-Authors: P H Gustavsen, A Høegholm, L E Bang, K S KristensenAbstract:The objective of this paper was to evaluate the Cardiovascular Risk in white coat hypertension (WCH). WCH is a well-known clinical entity defined by persistently elevated blood pressure (BP) in the doctor's office, whereas BP in other conditions is normal. The prognosis of WCH is unsettled, although two prospective studies that include normal control groups imply that the condition is benign. This study is a 10-year follow-up study on 420 patients with grade I–II hypertension newly diagnosed by their general practitioner and 146 normal controls (NTs). Ambulatory blood pressure (ABP) monitoring was performed at baseline. With our protocollated cutoff value of daytime-ABP
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white coat hypertension is a Cardiovascular Risk Factor a 10 year follow up study
Journal of Human Hypertension, 2003Co-Authors: P H Gustavsen, A Høegholm, L E Bang, K S KristensenAbstract:The objective of this paper was to evaluate the Cardiovascular Risk in white coat hypertension (WCH). WCH is a well-known clinical entity defined by persistently elevated blood pressure (BP) in the doctor's office, whereas BP in other conditions is normal. The prognosis of WCH is unsettled, although two prospective studies that include normal control groups imply that the condition is benign. This study is a 10-year follow-up study on 420 patients with grade I–II hypertension newly diagnosed by their general practitioner and 146 normal controls (NTs). Ambulatory blood pressure (ABP) monitoring was performed at baseline. With our protocollated cutoff value of daytime-ABP <135/90 mmHg, 76 (18.1%) of the 420 hypertensives were white coat hypertensives (WCHs) and 344 were established hypertensives (EHs). With a lower cutoff of 135/85 mmHg, 40 (9.5%) were WCHs. Complete follow-up data were obtained for all 566 subjects. The mean duration of follow-up was 10.2 years (range 9.0–12.5). In the WCH group, 14 first events were recorded (18.4%) consisting of two Cardiovascular deaths and 12 nonfatal Cardiovascular events. In the EH group, the corresponding number of events were 56 first events (16.3%), 12 Cardiovascular deaths and 44 nonfatal Cardiovascular events, and in the NT group 10 first events (6.8%), two Cardiovascular deaths and eight nonfatal Cardiovascular events. The event rate was similar in the WCH group and the EH group and significantly lower in the NT group (P<0.05). When corrected for daytime-ABP, age and other confounders, the difference remained statistically significant. When using the lower cutoff of 135/85 mmHg, WCH was still associated with a significantly higher Cardiovascular event rate. In conclusion, the main finding of this 10-year follow-up study is an increased Cardiovascular Risk in WCH compared to normotensive controls.
Robert Mckeown - One of the best experts on this subject based on the ideXlab platform.
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Sugar-sweetened and diet beverage consumption is associated with Cardiovascular Risk Factor profile in youth with type 1 diabetes
Acta Diabetologica, 2011Co-Authors: Andrey V. Bortsov, Angela D. Liese, Ronny A. Bell, Dana Dabelea, Ralph B. D’agostino, Richard F. Hamman, Georgeanna J. Klingensmith, Jean M. Lawrence, David M. Maahs, Robert MckeownAbstract:The prevalence of Cardiovascular disease (CVD) Risk Factors among youth with type 1 diabetes is high and associated with age, gender, and race/ethnicity. It has also been shown that youth with type 1 diabetes often do not follow dietary recommendations. The objective of this cross-sectional observational study was to explore the association of sugar-sweetened and diet beverage intake with A1c, plasma lipids, adiponectin, leptin, systolic, and diastolic blood pressure in youth with type 1 diabetes. We examined data from 1,806 youth age 10–22 years with type 1 diabetes, of which 22% were minority (10% Hispanic, 8% African Americans, 4% other races) and 48% were female. Sugar-sweetened beverage, diet beverage, and mineral water intake was assessed with a food frequency questionnaire. After adjustment for socio-demographic and clinical covariates, physical activity and total energy intake, high sugar-sweetened beverage intake (at least one serving per day vs. none), was associated with higher levels of total cholesterol, LDL cholesterol, and plasma triglycerides, but not with A1c. High diet beverage intake was associated with higher A1c, total cholesterol, LDL cholesterol, and triglycerides. These associations were partially confounded by body mass index, saturated fat and total fiber intake. High sugar-sweetened beverage intake may have an adverse effect on CVD Risk in youth with type 1 diabetes. Diet beverage intake may be a marker of unhealthy lifestyle which, in turn, is associated with worse metabolic control and CVD Risk profile in these youth. Youth with diabetes should be encouraged to minimize sugar-sweetened beverage intake.
L E Bang - One of the best experts on this subject based on the ideXlab platform.
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White coat hypertension is a Cardiovascular Risk Factor: a 10-year follow-up study
Journal of Human Hypertension, 2003Co-Authors: P H Gustavsen, A Høegholm, L E Bang, K S KristensenAbstract:The objective of this paper was to evaluate the Cardiovascular Risk in white coat hypertension (WCH). WCH is a well-known clinical entity defined by persistently elevated blood pressure (BP) in the doctor's office, whereas BP in other conditions is normal. The prognosis of WCH is unsettled, although two prospective studies that include normal control groups imply that the condition is benign. This study is a 10-year follow-up study on 420 patients with grade I–II hypertension newly diagnosed by their general practitioner and 146 normal controls (NTs). Ambulatory blood pressure (ABP) monitoring was performed at baseline. With our protocollated cutoff value of daytime-ABP
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white coat hypertension is a Cardiovascular Risk Factor a 10 year follow up study
Journal of Human Hypertension, 2003Co-Authors: P H Gustavsen, A Høegholm, L E Bang, K S KristensenAbstract:The objective of this paper was to evaluate the Cardiovascular Risk in white coat hypertension (WCH). WCH is a well-known clinical entity defined by persistently elevated blood pressure (BP) in the doctor's office, whereas BP in other conditions is normal. The prognosis of WCH is unsettled, although two prospective studies that include normal control groups imply that the condition is benign. This study is a 10-year follow-up study on 420 patients with grade I–II hypertension newly diagnosed by their general practitioner and 146 normal controls (NTs). Ambulatory blood pressure (ABP) monitoring was performed at baseline. With our protocollated cutoff value of daytime-ABP <135/90 mmHg, 76 (18.1%) of the 420 hypertensives were white coat hypertensives (WCHs) and 344 were established hypertensives (EHs). With a lower cutoff of 135/85 mmHg, 40 (9.5%) were WCHs. Complete follow-up data were obtained for all 566 subjects. The mean duration of follow-up was 10.2 years (range 9.0–12.5). In the WCH group, 14 first events were recorded (18.4%) consisting of two Cardiovascular deaths and 12 nonfatal Cardiovascular events. In the EH group, the corresponding number of events were 56 first events (16.3%), 12 Cardiovascular deaths and 44 nonfatal Cardiovascular events, and in the NT group 10 first events (6.8%), two Cardiovascular deaths and eight nonfatal Cardiovascular events. The event rate was similar in the WCH group and the EH group and significantly lower in the NT group (P<0.05). When corrected for daytime-ABP, age and other confounders, the difference remained statistically significant. When using the lower cutoff of 135/85 mmHg, WCH was still associated with a significantly higher Cardiovascular event rate. In conclusion, the main finding of this 10-year follow-up study is an increased Cardiovascular Risk in WCH compared to normotensive controls.
A Høegholm - One of the best experts on this subject based on the ideXlab platform.
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White coat hypertension is a Cardiovascular Risk Factor: a 10-year follow-up study
Journal of Human Hypertension, 2003Co-Authors: P H Gustavsen, A Høegholm, L E Bang, K S KristensenAbstract:The objective of this paper was to evaluate the Cardiovascular Risk in white coat hypertension (WCH). WCH is a well-known clinical entity defined by persistently elevated blood pressure (BP) in the doctor's office, whereas BP in other conditions is normal. The prognosis of WCH is unsettled, although two prospective studies that include normal control groups imply that the condition is benign. This study is a 10-year follow-up study on 420 patients with grade I–II hypertension newly diagnosed by their general practitioner and 146 normal controls (NTs). Ambulatory blood pressure (ABP) monitoring was performed at baseline. With our protocollated cutoff value of daytime-ABP
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white coat hypertension is a Cardiovascular Risk Factor a 10 year follow up study
Journal of Human Hypertension, 2003Co-Authors: P H Gustavsen, A Høegholm, L E Bang, K S KristensenAbstract:The objective of this paper was to evaluate the Cardiovascular Risk in white coat hypertension (WCH). WCH is a well-known clinical entity defined by persistently elevated blood pressure (BP) in the doctor's office, whereas BP in other conditions is normal. The prognosis of WCH is unsettled, although two prospective studies that include normal control groups imply that the condition is benign. This study is a 10-year follow-up study on 420 patients with grade I–II hypertension newly diagnosed by their general practitioner and 146 normal controls (NTs). Ambulatory blood pressure (ABP) monitoring was performed at baseline. With our protocollated cutoff value of daytime-ABP <135/90 mmHg, 76 (18.1%) of the 420 hypertensives were white coat hypertensives (WCHs) and 344 were established hypertensives (EHs). With a lower cutoff of 135/85 mmHg, 40 (9.5%) were WCHs. Complete follow-up data were obtained for all 566 subjects. The mean duration of follow-up was 10.2 years (range 9.0–12.5). In the WCH group, 14 first events were recorded (18.4%) consisting of two Cardiovascular deaths and 12 nonfatal Cardiovascular events. In the EH group, the corresponding number of events were 56 first events (16.3%), 12 Cardiovascular deaths and 44 nonfatal Cardiovascular events, and in the NT group 10 first events (6.8%), two Cardiovascular deaths and eight nonfatal Cardiovascular events. The event rate was similar in the WCH group and the EH group and significantly lower in the NT group (P<0.05). When corrected for daytime-ABP, age and other confounders, the difference remained statistically significant. When using the lower cutoff of 135/85 mmHg, WCH was still associated with a significantly higher Cardiovascular event rate. In conclusion, the main finding of this 10-year follow-up study is an increased Cardiovascular Risk in WCH compared to normotensive controls.