The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

Jeffrey E Metter - One of the best experts on this subject based on the ideXlab platform.

  • Carotid intimal medial thickness predicts cognitive decline among adults without clinical vascular disease
    Stroke, 2009
    Co-Authors: Carrington R Wendell, Jeffrey E Metter, Alan B Zonderman, Samer S Najjar, Shari R Waldstein
    Abstract:

    Background and Purpose— Though clinical cardiovascular and cerebrovascular diseases are established risk factors for cognitive decline and dementia, less is known about the relations between vascular health and cognition among individuals without these diseases. Carotid intimal medial thickness (IMT), a measure of subclinical vascular disease, is associated with concurrent decrements in cognitive function, but relatively little research has examined longitudinal relations between Carotid IMT and prospective cognitive decline. Methods— We examined relations of Carotid IMT to prospective trajectories of cognitive function among 538 (aged 20 to 93, 39% male, 66% white) participants in the Baltimore Longitudinal Study of Aging (BLSA) free of known cardiovascular, cerebrovascular, and neurological disease. Participants underwent initial Carotid Ultrasonography and repeat neuropsychological testing on up to 8 occasions over up to 11 years of follow-up. Mixed-effects regression analyses were adjusted for age, ge...

  • Carotid arterial stiffness as a surrogate for aortic stiffness relationship between Carotid artery pressure strain elastic modulus and aortic pulse wave velocity
    Ultrasound in Medicine and Biology, 1999
    Co-Authors: Yoji Nagai, Mary K Kemper, Tomasz M Rywik, Christopher J Earley, Jerome L Fleg, Jeffrey E Metter
    Abstract:

    Abstract Common Carotid arterial (CCA) stiffness can be assessed during Carotid Ultrasonography, but its association with aortic stiffness, a well-defined cardiovascular risk factor, has not been clarified. This study examines the relationship between CCA and aortic stiffness. CCA pressure–strain elastic modulus (Ep) and aortic pulse wave velocity (APWV) were evaluated in 110 healthy volunteers (age 56.2 ± 14.6 y) by B-mode and Doppler Ultrasonography. CCA Ep increased linearly with age and was higher in men than in women (model r2 = 0.50, p

  • Carotid arterial stiffness as a surrogate for aortic stiffness relationship between Carotid artery pressure strain elastic modulus and aortic pulse wave velocity
    Ultrasound in Medicine and Biology, 1999
    Co-Authors: Yoji Nagai, Mary K Kemper, Tomasz M Rywik, Christopher J Earley, Jerome L Fleg, Jeffrey E Metter
    Abstract:

    Common Carotid arterial (CCA) stiffness can be assessed during Carotid Ultrasonography, but its association with aortic stiffness, a well-defined cardiovascular risk factor, has not been clarified. This study examines the relationship between CCA and aortic stiffness. CCA pressure–strain elastic modulus (Ep) and aortic pulse wave velocity (APWV) were evaluated in 110 healthy volunteers (age 56.2 ± 14.6 y) by B-mode and Doppler Ultrasonography. CCA Ep increased linearly with age and was higher in men than in women (model r2 = 0.50, p < 0.001). APWV increased quadratically with age (model r2 = 0.54, p < 0.001), similarly for women and men. Both CCA Ep and APWV were linearly associated with systolic blood pressure (BP) (r = 0.53 and 0.46, respectively) but not with diastolic BP. A linear relationship was found between CCA Ep and APWV (APWV = 194.7 + 5.67 × Ep [model r2 = 0.42, p < 0.001]). CCA Ep was associated with APWV (p < 0.001) independent of age, gender, and BP (model r2 = 0.62, p < 0.001), and the most parsimonious model to explain APWV included CCA Ep and age (APWV = 601.73 − 15.64 × age + 0.223 × age2 + 2.69 × Ep [model r2 = 0.60, p < 0.001]). Thus, CCA Ep is moderately associated with APWV. CCA stiffness as assessed by B-mode may be useful as a surrogate for aortic stiffness.

Yoji Nagai - One of the best experts on this subject based on the ideXlab platform.

  • equivalence of plaque score and intima media thickness of Carotid Ultrasonography for predicting severe coronary artery lesion
    Ultrasound in Medicine and Biology, 2003
    Co-Authors: Manabu Sakaguchi, Yoji Nagai, Kazuo Kitagawa, Hiroshi Yamagami, Kimito Kondo, Kohji Matsushita, Naohiko Oku, Hidetaka Hougaku, Toshiho Ohtsuki, Tohru Masuyama
    Abstract:

    Abstract Carotid atherosclerosis appears to be predictive of myocardial infarction. Because several sonographical indices are available for Carotid ultrasound (US), we compared “blindly” the potential utilities of those indices for predicting coronary lesions in 270 patients. Carotid atherosclerosis was evaluated by the following four indices: plaque score (PlaS), intima-media thickness (IMT) of common Carotid artery (CCA-IMT), IMT of bulb to internal Carotid artery (Bulb-ICA-IMT), and combined IMT measurement from all segments. The existence of coronary lesions was diagnosed by > 50% stenosis in diameter in coronary arteries. All indices were associated with coronary lesions independent of risk factors. By receiver-operating characteristic (ROC) curve analyses, ROC areas defined by Bulb-ICA-IMT (0.76 to 0.86), combined IMT (0.76 to 0.86) and PS (0.76 to 0.87) were greater than that defined by CCA-IMT (0.64 to 0.76). In conclusion, PlaS, Bulb-ICA-IMT and combined IMT are equally effective and could be better than CCA-IMT for predicting coronary lesions in a population with cardiovascular risk.

  • Carotid arterial stiffness as a surrogate for aortic stiffness relationship between Carotid artery pressure strain elastic modulus and aortic pulse wave velocity
    Ultrasound in Medicine and Biology, 1999
    Co-Authors: Yoji Nagai, Mary K Kemper, Tomasz M Rywik, Christopher J Earley, Jerome L Fleg, Jeffrey E Metter
    Abstract:

    Abstract Common Carotid arterial (CCA) stiffness can be assessed during Carotid Ultrasonography, but its association with aortic stiffness, a well-defined cardiovascular risk factor, has not been clarified. This study examines the relationship between CCA and aortic stiffness. CCA pressure–strain elastic modulus (Ep) and aortic pulse wave velocity (APWV) were evaluated in 110 healthy volunteers (age 56.2 ± 14.6 y) by B-mode and Doppler Ultrasonography. CCA Ep increased linearly with age and was higher in men than in women (model r2 = 0.50, p

  • Carotid arterial stiffness as a surrogate for aortic stiffness relationship between Carotid artery pressure strain elastic modulus and aortic pulse wave velocity
    Ultrasound in Medicine and Biology, 1999
    Co-Authors: Yoji Nagai, Mary K Kemper, Tomasz M Rywik, Christopher J Earley, Jerome L Fleg, Jeffrey E Metter
    Abstract:

    Common Carotid arterial (CCA) stiffness can be assessed during Carotid Ultrasonography, but its association with aortic stiffness, a well-defined cardiovascular risk factor, has not been clarified. This study examines the relationship between CCA and aortic stiffness. CCA pressure–strain elastic modulus (Ep) and aortic pulse wave velocity (APWV) were evaluated in 110 healthy volunteers (age 56.2 ± 14.6 y) by B-mode and Doppler Ultrasonography. CCA Ep increased linearly with age and was higher in men than in women (model r2 = 0.50, p < 0.001). APWV increased quadratically with age (model r2 = 0.54, p < 0.001), similarly for women and men. Both CCA Ep and APWV were linearly associated with systolic blood pressure (BP) (r = 0.53 and 0.46, respectively) but not with diastolic BP. A linear relationship was found between CCA Ep and APWV (APWV = 194.7 + 5.67 × Ep [model r2 = 0.42, p < 0.001]). CCA Ep was associated with APWV (p < 0.001) independent of age, gender, and BP (model r2 = 0.62, p < 0.001), and the most parsimonious model to explain APWV included CCA Ep and age (APWV = 601.73 − 15.64 × age + 0.223 × age2 + 2.69 × Ep [model r2 = 0.60, p < 0.001]). Thus, CCA Ep is moderately associated with APWV. CCA stiffness as assessed by B-mode may be useful as a surrogate for aortic stiffness.

Takenori Yamaguchi - One of the best experts on this subject based on the ideXlab platform.

  • oscillating thromboemboli within the extracranial internal Carotid artery demonstrated by Ultrasonography in patients with acute cardioembolic stroke
    Ultrasound in Medicine and Biology, 1998
    Co-Authors: Kazumi Kimura, Masahiro Yasaka, Kuniyasu Wada, Kazuo Minematsu, Makoto Uchino, Kiminobu Yonemura, Jun Ogata, Takenori Yamaguchi
    Abstract:

    We detected oscillating thromboemboli at the extracranial internal Carotid artery (ICA) by duplex Carotid Ultrasonography in patients with acute cardioembolic stroke. Using B-mode Ultrasonography, we evaluated the extracranial ICA in 11 patients with acute cardioembolic ICA occlusion. A homogeneous, elastic, oscillating intraluminal mass echo originating in the extracranial ICA extended distally in 5 (46%) of these patients. The echoes moved quickly and distally during the systolic phase of the cardiac cycle and returned slowly to the original position during the diastolic phase. We performed a postmortem study 24 days after stroke onset in 1 patient with an oscillating intraluminal mass echo that had been demonstrated by duplex Ultrasonography. The ICA lumen was obstructed with a fresh string-like thrombus. The findings of oscillating intraluminal mass echo may help establish a diagnosis of acute embolic ICA occlusion.

  • transoral Carotid Ultrasonography
    Stroke, 1998
    Co-Authors: Masahiro Yasaka, Kazumi Kimura, Ryoichi Otsubo, Katsunori Isa, Kuniyasu Wada, Kazuyuki Nagatsuka, Kazuo Minematsu, Takenori Yamaguchi
    Abstract:

    Background and Purpose—We attempted ultrasonographic evaluation of the distal extracranial internal Carotid artery (ICA) using the transoral method (transoral Carotid Ultrasonography [TOCU]). Metho...

  • ultrasonic evaluation of the site of Carotid axis occlusion in patients with acute cardioembolic stroke
    Stroke, 1992
    Co-Authors: Masahiro Yasaka, T Omae, Takashi Tsuchiya, Takenori Yamaguchi
    Abstract:

    We performed the present study to determine whether the site of cardioembolic occlusion in the Carotid axis could be identified by end-diastolic velocity measurements of the common Carotid arteries.Using duplex Carotid Ultrasonography, we measured the flow velocity in the common Carotid arteries and calculated the side-to-side ratios of the end-diastolic velocity (ED ratio; the end-diastolic velocity of the nonaffected side divided by that of the affected side) in 46 patients with acute cardioembolic stroke. The velocity on the faster side was divided by the slower velocity to obtain the normal values of ED ratio in 30 controls. The ED ratios were compared with the angiographic findings, in which unilateral intracranial internal Carotid artery occlusion was present in 20 patients (IC group), occlusion of the horizontal segment of the middle cerebral artery was present in 16 patients (M1 group), and branch occlusion of the middle cerebral artery was present in 10 patients (MBr group). The ED ratios of the ...

Mary K Kemper - One of the best experts on this subject based on the ideXlab platform.

  • Carotid arterial stiffness as a surrogate for aortic stiffness relationship between Carotid artery pressure strain elastic modulus and aortic pulse wave velocity
    Ultrasound in Medicine and Biology, 1999
    Co-Authors: Yoji Nagai, Mary K Kemper, Tomasz M Rywik, Christopher J Earley, Jerome L Fleg, Jeffrey E Metter
    Abstract:

    Abstract Common Carotid arterial (CCA) stiffness can be assessed during Carotid Ultrasonography, but its association with aortic stiffness, a well-defined cardiovascular risk factor, has not been clarified. This study examines the relationship between CCA and aortic stiffness. CCA pressure–strain elastic modulus (Ep) and aortic pulse wave velocity (APWV) were evaluated in 110 healthy volunteers (age 56.2 ± 14.6 y) by B-mode and Doppler Ultrasonography. CCA Ep increased linearly with age and was higher in men than in women (model r2 = 0.50, p

  • Carotid arterial stiffness as a surrogate for aortic stiffness relationship between Carotid artery pressure strain elastic modulus and aortic pulse wave velocity
    Ultrasound in Medicine and Biology, 1999
    Co-Authors: Yoji Nagai, Mary K Kemper, Tomasz M Rywik, Christopher J Earley, Jerome L Fleg, Jeffrey E Metter
    Abstract:

    Common Carotid arterial (CCA) stiffness can be assessed during Carotid Ultrasonography, but its association with aortic stiffness, a well-defined cardiovascular risk factor, has not been clarified. This study examines the relationship between CCA and aortic stiffness. CCA pressure–strain elastic modulus (Ep) and aortic pulse wave velocity (APWV) were evaluated in 110 healthy volunteers (age 56.2 ± 14.6 y) by B-mode and Doppler Ultrasonography. CCA Ep increased linearly with age and was higher in men than in women (model r2 = 0.50, p < 0.001). APWV increased quadratically with age (model r2 = 0.54, p < 0.001), similarly for women and men. Both CCA Ep and APWV were linearly associated with systolic blood pressure (BP) (r = 0.53 and 0.46, respectively) but not with diastolic BP. A linear relationship was found between CCA Ep and APWV (APWV = 194.7 + 5.67 × Ep [model r2 = 0.42, p < 0.001]). CCA Ep was associated with APWV (p < 0.001) independent of age, gender, and BP (model r2 = 0.62, p < 0.001), and the most parsimonious model to explain APWV included CCA Ep and age (APWV = 601.73 − 15.64 × age + 0.223 × age2 + 2.69 × Ep [model r2 = 0.60, p < 0.001]). Thus, CCA Ep is moderately associated with APWV. CCA stiffness as assessed by B-mode may be useful as a surrogate for aortic stiffness.

Tomasz M Rywik - One of the best experts on this subject based on the ideXlab platform.

  • Carotid arterial stiffness as a surrogate for aortic stiffness relationship between Carotid artery pressure strain elastic modulus and aortic pulse wave velocity
    Ultrasound in Medicine and Biology, 1999
    Co-Authors: Yoji Nagai, Mary K Kemper, Tomasz M Rywik, Christopher J Earley, Jerome L Fleg, Jeffrey E Metter
    Abstract:

    Abstract Common Carotid arterial (CCA) stiffness can be assessed during Carotid Ultrasonography, but its association with aortic stiffness, a well-defined cardiovascular risk factor, has not been clarified. This study examines the relationship between CCA and aortic stiffness. CCA pressure–strain elastic modulus (Ep) and aortic pulse wave velocity (APWV) were evaluated in 110 healthy volunteers (age 56.2 ± 14.6 y) by B-mode and Doppler Ultrasonography. CCA Ep increased linearly with age and was higher in men than in women (model r2 = 0.50, p

  • Carotid arterial stiffness as a surrogate for aortic stiffness relationship between Carotid artery pressure strain elastic modulus and aortic pulse wave velocity
    Ultrasound in Medicine and Biology, 1999
    Co-Authors: Yoji Nagai, Mary K Kemper, Tomasz M Rywik, Christopher J Earley, Jerome L Fleg, Jeffrey E Metter
    Abstract:

    Common Carotid arterial (CCA) stiffness can be assessed during Carotid Ultrasonography, but its association with aortic stiffness, a well-defined cardiovascular risk factor, has not been clarified. This study examines the relationship between CCA and aortic stiffness. CCA pressure–strain elastic modulus (Ep) and aortic pulse wave velocity (APWV) were evaluated in 110 healthy volunteers (age 56.2 ± 14.6 y) by B-mode and Doppler Ultrasonography. CCA Ep increased linearly with age and was higher in men than in women (model r2 = 0.50, p < 0.001). APWV increased quadratically with age (model r2 = 0.54, p < 0.001), similarly for women and men. Both CCA Ep and APWV were linearly associated with systolic blood pressure (BP) (r = 0.53 and 0.46, respectively) but not with diastolic BP. A linear relationship was found between CCA Ep and APWV (APWV = 194.7 + 5.67 × Ep [model r2 = 0.42, p < 0.001]). CCA Ep was associated with APWV (p < 0.001) independent of age, gender, and BP (model r2 = 0.62, p < 0.001), and the most parsimonious model to explain APWV included CCA Ep and age (APWV = 601.73 − 15.64 × age + 0.223 × age2 + 2.69 × Ep [model r2 = 0.60, p < 0.001]). Thus, CCA Ep is moderately associated with APWV. CCA stiffness as assessed by B-mode may be useful as a surrogate for aortic stiffness.