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Bruno Hoen - One of the best experts on this subject based on the ideXlab platform.

  • Streptococcus bovis/Streptococcus equinus complex fecal Carriage, colorectal carcinoma, and infective endocarditis: a new appraisal of a complex connection.
    European Journal of Clinical Microbiology and Infectious Diseases, 2013
    Co-Authors: Catherine Chirouze, Isabelle Patry, Xavier Duval, V Baty, Pierre Tattevin, T Aparicio, M Pagenault, F Carbonnel, G Couetdic, Bruno Hoen
    Abstract:

    The proportion of group D streptococcal infective endocarditis (IE) (predominantly due to Streptococcus gallolyticus) and the incidence of colorectal cancer are higher in France than in most European countries. We assumed that this could be explained by a high group D streptococci (GDS) fecal Carriage rate. The aims of this study were to re-assess the GDS fecal Carriage rate in France and its relationship with colorectal cancer. Consecutive adult subjects who were to undergo a complete colonoscopy were invited to participate. GDS were searched in subjects' stools before their colonoscopy using biomolecular techniques. Colonoscopic findings were sorted into four subgroups: normal colonoscopy, non-tumoral lesions, benign tumors, and premalignant/malignant tumors. GDS fecal Carriages were calculated overall and in each subgroup and compared. The data from 259 subjects were analyzed. GDS were identified in the feces of 12 subjects, with the following distribution: S. lutetiensis (n = 9), S. pasteurianus (n = 2), and S. gallolyticus (n = 1). This accounted for an overall GDS fecal Carriage rate of 4.6 %. The GDS fecal Carriage rate was 6 % in case of normal colonoscopy, 1.3 % in case of non-tumoral lesions, 3.2 % in case of benign tumors, and 11 % in case of premalignant/malignant tumors. These four percentages were not statistically different. The GDS fecal Carriage rate was lower than expected, which did not confirm our working hypothesis. Most strains belonged to S. bovis biotype II, while S. gallolyticus was found only once. These findings suggest that different GDS play different roles in the etiopathogenesis of IE and colorectal cancer.

  • streptococcus bovis streptococcus equinus complex fecal Carriage colorectal carcinoma and infective endocarditis a new appraisal of a complex connection
    European Journal of Clinical Microbiology & Infectious Diseases, 2013
    Co-Authors: Catherine Chirouze, Isabelle Patry, Xavier Duval, V Baty, Pierre Tattevin, T Aparicio, M Pagenault, F Carbonnel, G Couetdic, Bruno Hoen
    Abstract:

    The proportion of group D streptococcal infective endocarditis (IE) (predominantly due to Streptococcus gallolyticus) and the incidence of colorectal cancer are higher in France than in most European countries. We assumed that this could be explained by a high group D streptococci (GDS) fecal Carriage rate. The aims of this study were to re-assess the GDS fecal Carriage rate in France and its relationship with colorectal cancer. Consecutive adult subjects who were to undergo a complete colonoscopy were invited to participate. GDS were searched in subjects’ stools before their colonoscopy using biomolecular techniques. Colonoscopic findings were sorted into four subgroups: normal colonoscopy, non-tumoral lesions, benign tumors, and premalignant/malignant tumors. GDS fecal Carriages were calculated overall and in each subgroup and compared. The data from 259 subjects were analyzed. GDS were identified in the feces of 12 subjects, with the following distribution: S. lutetiensis (n = 9), S. pasteurianus (n = 2), and S. gallolyticus (n = 1). This accounted for an overall GDS fecal Carriage rate of 4.6 %. The GDS fecal Carriage rate was 6 % in case of normal colonoscopy, 1.3 % in case of non-tumoral lesions, 3.2 % in case of benign tumors, and 11 % in case of premalignant/malignant tumors. These four percentages were not statistically different. The GDS fecal Carriage rate was lower than expected, which did not confirm our working hypothesis. Most strains belonged to S. bovis biotype II, while S. gallolyticus was found only once. These findings suggest that different GDS play different roles in the etiopathogenesis of IE and colorectal cancer.

Catherine Chirouze - One of the best experts on this subject based on the ideXlab platform.

  • Streptococcus bovis/Streptococcus equinus complex fecal Carriage, colorectal carcinoma, and infective endocarditis: a new appraisal of a complex connection.
    European Journal of Clinical Microbiology and Infectious Diseases, 2013
    Co-Authors: Catherine Chirouze, Isabelle Patry, Xavier Duval, V Baty, Pierre Tattevin, T Aparicio, M Pagenault, F Carbonnel, G Couetdic, Bruno Hoen
    Abstract:

    The proportion of group D streptococcal infective endocarditis (IE) (predominantly due to Streptococcus gallolyticus) and the incidence of colorectal cancer are higher in France than in most European countries. We assumed that this could be explained by a high group D streptococci (GDS) fecal Carriage rate. The aims of this study were to re-assess the GDS fecal Carriage rate in France and its relationship with colorectal cancer. Consecutive adult subjects who were to undergo a complete colonoscopy were invited to participate. GDS were searched in subjects' stools before their colonoscopy using biomolecular techniques. Colonoscopic findings were sorted into four subgroups: normal colonoscopy, non-tumoral lesions, benign tumors, and premalignant/malignant tumors. GDS fecal Carriages were calculated overall and in each subgroup and compared. The data from 259 subjects were analyzed. GDS were identified in the feces of 12 subjects, with the following distribution: S. lutetiensis (n = 9), S. pasteurianus (n = 2), and S. gallolyticus (n = 1). This accounted for an overall GDS fecal Carriage rate of 4.6 %. The GDS fecal Carriage rate was 6 % in case of normal colonoscopy, 1.3 % in case of non-tumoral lesions, 3.2 % in case of benign tumors, and 11 % in case of premalignant/malignant tumors. These four percentages were not statistically different. The GDS fecal Carriage rate was lower than expected, which did not confirm our working hypothesis. Most strains belonged to S. bovis biotype II, while S. gallolyticus was found only once. These findings suggest that different GDS play different roles in the etiopathogenesis of IE and colorectal cancer.

  • streptococcus bovis streptococcus equinus complex fecal Carriage colorectal carcinoma and infective endocarditis a new appraisal of a complex connection
    European Journal of Clinical Microbiology & Infectious Diseases, 2013
    Co-Authors: Catherine Chirouze, Isabelle Patry, Xavier Duval, V Baty, Pierre Tattevin, T Aparicio, M Pagenault, F Carbonnel, G Couetdic, Bruno Hoen
    Abstract:

    The proportion of group D streptococcal infective endocarditis (IE) (predominantly due to Streptococcus gallolyticus) and the incidence of colorectal cancer are higher in France than in most European countries. We assumed that this could be explained by a high group D streptococci (GDS) fecal Carriage rate. The aims of this study were to re-assess the GDS fecal Carriage rate in France and its relationship with colorectal cancer. Consecutive adult subjects who were to undergo a complete colonoscopy were invited to participate. GDS were searched in subjects’ stools before their colonoscopy using biomolecular techniques. Colonoscopic findings were sorted into four subgroups: normal colonoscopy, non-tumoral lesions, benign tumors, and premalignant/malignant tumors. GDS fecal Carriages were calculated overall and in each subgroup and compared. The data from 259 subjects were analyzed. GDS were identified in the feces of 12 subjects, with the following distribution: S. lutetiensis (n = 9), S. pasteurianus (n = 2), and S. gallolyticus (n = 1). This accounted for an overall GDS fecal Carriage rate of 4.6 %. The GDS fecal Carriage rate was 6 % in case of normal colonoscopy, 1.3 % in case of non-tumoral lesions, 3.2 % in case of benign tumors, and 11 % in case of premalignant/malignant tumors. These four percentages were not statistically different. The GDS fecal Carriage rate was lower than expected, which did not confirm our working hypothesis. Most strains belonged to S. bovis biotype II, while S. gallolyticus was found only once. These findings suggest that different GDS play different roles in the etiopathogenesis of IE and colorectal cancer.

Todd D Swarthou - One of the best experts on this subject based on the ideXlab platform.

  • high residual Carriage of vaccine serotype streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in malawi
    Nature Communications, 2020
    Co-Authors: Todd D Swarthou, Claudio Fronterre, Jose Lourenco, Uri Obolski, Andrea Gori, Nao Arzeev, Dea Evere
    Abstract:

    There are concerns that pneumococcal conjugate vaccines (PCVs) in sub-Saharan Africa sub-optimally interrupt Streptococcus pneumoniae vaccine-serotype (VT) Carriage and transmission. Here we assess PCV Carriage using rolling, prospective nasopharyngeal Carriage surveys between 2015 and 2018, 3.6–7.1 years after Malawi’s 2011 PCV13 introduction. Carriage decay rate is analysed using non-linear regression. Despite evidence of reduction in VT Carriage over the study period, there is high persistent residual Carriage. This includes among PCV-vaccinated children 3–5-year-old (16.1% relative reduction from 19.9% to 16.7%); PCV-unvaccinated children 6–8-year-old (40.5% reduction from 26.4% to 15.7%); HIV-infected adults 18-40-years-old on antiretroviral therapy (41.4% reduction from 15.2% to 8.9%). VT Carriage prevalence half-life is similar among PCV-vaccinated and PCV-unvaccinated children (3.26 and 3.34 years, respectively). Compared with high-income settings, there is high residual VT Carriage 3.6–7.1 years after PCV introduction. Rigorous evaluation of strategies to augment vaccine-induced control of Carriage, including alternative schedules and catch-up campaigns, is required.

T Aparicio - One of the best experts on this subject based on the ideXlab platform.

  • Streptococcus bovis/Streptococcus equinus complex fecal Carriage, colorectal carcinoma, and infective endocarditis: a new appraisal of a complex connection.
    European Journal of Clinical Microbiology and Infectious Diseases, 2013
    Co-Authors: Catherine Chirouze, Isabelle Patry, Xavier Duval, V Baty, Pierre Tattevin, T Aparicio, M Pagenault, F Carbonnel, G Couetdic, Bruno Hoen
    Abstract:

    The proportion of group D streptococcal infective endocarditis (IE) (predominantly due to Streptococcus gallolyticus) and the incidence of colorectal cancer are higher in France than in most European countries. We assumed that this could be explained by a high group D streptococci (GDS) fecal Carriage rate. The aims of this study were to re-assess the GDS fecal Carriage rate in France and its relationship with colorectal cancer. Consecutive adult subjects who were to undergo a complete colonoscopy were invited to participate. GDS were searched in subjects' stools before their colonoscopy using biomolecular techniques. Colonoscopic findings were sorted into four subgroups: normal colonoscopy, non-tumoral lesions, benign tumors, and premalignant/malignant tumors. GDS fecal Carriages were calculated overall and in each subgroup and compared. The data from 259 subjects were analyzed. GDS were identified in the feces of 12 subjects, with the following distribution: S. lutetiensis (n = 9), S. pasteurianus (n = 2), and S. gallolyticus (n = 1). This accounted for an overall GDS fecal Carriage rate of 4.6 %. The GDS fecal Carriage rate was 6 % in case of normal colonoscopy, 1.3 % in case of non-tumoral lesions, 3.2 % in case of benign tumors, and 11 % in case of premalignant/malignant tumors. These four percentages were not statistically different. The GDS fecal Carriage rate was lower than expected, which did not confirm our working hypothesis. Most strains belonged to S. bovis biotype II, while S. gallolyticus was found only once. These findings suggest that different GDS play different roles in the etiopathogenesis of IE and colorectal cancer.

  • streptococcus bovis streptococcus equinus complex fecal Carriage colorectal carcinoma and infective endocarditis a new appraisal of a complex connection
    European Journal of Clinical Microbiology & Infectious Diseases, 2013
    Co-Authors: Catherine Chirouze, Isabelle Patry, Xavier Duval, V Baty, Pierre Tattevin, T Aparicio, M Pagenault, F Carbonnel, G Couetdic, Bruno Hoen
    Abstract:

    The proportion of group D streptococcal infective endocarditis (IE) (predominantly due to Streptococcus gallolyticus) and the incidence of colorectal cancer are higher in France than in most European countries. We assumed that this could be explained by a high group D streptococci (GDS) fecal Carriage rate. The aims of this study were to re-assess the GDS fecal Carriage rate in France and its relationship with colorectal cancer. Consecutive adult subjects who were to undergo a complete colonoscopy were invited to participate. GDS were searched in subjects’ stools before their colonoscopy using biomolecular techniques. Colonoscopic findings were sorted into four subgroups: normal colonoscopy, non-tumoral lesions, benign tumors, and premalignant/malignant tumors. GDS fecal Carriages were calculated overall and in each subgroup and compared. The data from 259 subjects were analyzed. GDS were identified in the feces of 12 subjects, with the following distribution: S. lutetiensis (n = 9), S. pasteurianus (n = 2), and S. gallolyticus (n = 1). This accounted for an overall GDS fecal Carriage rate of 4.6 %. The GDS fecal Carriage rate was 6 % in case of normal colonoscopy, 1.3 % in case of non-tumoral lesions, 3.2 % in case of benign tumors, and 11 % in case of premalignant/malignant tumors. These four percentages were not statistically different. The GDS fecal Carriage rate was lower than expected, which did not confirm our working hypothesis. Most strains belonged to S. bovis biotype II, while S. gallolyticus was found only once. These findings suggest that different GDS play different roles in the etiopathogenesis of IE and colorectal cancer.

M Pagenault - One of the best experts on this subject based on the ideXlab platform.

  • Streptococcus bovis/Streptococcus equinus complex fecal Carriage, colorectal carcinoma, and infective endocarditis: a new appraisal of a complex connection.
    European Journal of Clinical Microbiology and Infectious Diseases, 2013
    Co-Authors: Catherine Chirouze, Isabelle Patry, Xavier Duval, V Baty, Pierre Tattevin, T Aparicio, M Pagenault, F Carbonnel, G Couetdic, Bruno Hoen
    Abstract:

    The proportion of group D streptococcal infective endocarditis (IE) (predominantly due to Streptococcus gallolyticus) and the incidence of colorectal cancer are higher in France than in most European countries. We assumed that this could be explained by a high group D streptococci (GDS) fecal Carriage rate. The aims of this study were to re-assess the GDS fecal Carriage rate in France and its relationship with colorectal cancer. Consecutive adult subjects who were to undergo a complete colonoscopy were invited to participate. GDS were searched in subjects' stools before their colonoscopy using biomolecular techniques. Colonoscopic findings were sorted into four subgroups: normal colonoscopy, non-tumoral lesions, benign tumors, and premalignant/malignant tumors. GDS fecal Carriages were calculated overall and in each subgroup and compared. The data from 259 subjects were analyzed. GDS were identified in the feces of 12 subjects, with the following distribution: S. lutetiensis (n = 9), S. pasteurianus (n = 2), and S. gallolyticus (n = 1). This accounted for an overall GDS fecal Carriage rate of 4.6 %. The GDS fecal Carriage rate was 6 % in case of normal colonoscopy, 1.3 % in case of non-tumoral lesions, 3.2 % in case of benign tumors, and 11 % in case of premalignant/malignant tumors. These four percentages were not statistically different. The GDS fecal Carriage rate was lower than expected, which did not confirm our working hypothesis. Most strains belonged to S. bovis biotype II, while S. gallolyticus was found only once. These findings suggest that different GDS play different roles in the etiopathogenesis of IE and colorectal cancer.

  • streptococcus bovis streptococcus equinus complex fecal Carriage colorectal carcinoma and infective endocarditis a new appraisal of a complex connection
    European Journal of Clinical Microbiology & Infectious Diseases, 2013
    Co-Authors: Catherine Chirouze, Isabelle Patry, Xavier Duval, V Baty, Pierre Tattevin, T Aparicio, M Pagenault, F Carbonnel, G Couetdic, Bruno Hoen
    Abstract:

    The proportion of group D streptococcal infective endocarditis (IE) (predominantly due to Streptococcus gallolyticus) and the incidence of colorectal cancer are higher in France than in most European countries. We assumed that this could be explained by a high group D streptococci (GDS) fecal Carriage rate. The aims of this study were to re-assess the GDS fecal Carriage rate in France and its relationship with colorectal cancer. Consecutive adult subjects who were to undergo a complete colonoscopy were invited to participate. GDS were searched in subjects’ stools before their colonoscopy using biomolecular techniques. Colonoscopic findings were sorted into four subgroups: normal colonoscopy, non-tumoral lesions, benign tumors, and premalignant/malignant tumors. GDS fecal Carriages were calculated overall and in each subgroup and compared. The data from 259 subjects were analyzed. GDS were identified in the feces of 12 subjects, with the following distribution: S. lutetiensis (n = 9), S. pasteurianus (n = 2), and S. gallolyticus (n = 1). This accounted for an overall GDS fecal Carriage rate of 4.6 %. The GDS fecal Carriage rate was 6 % in case of normal colonoscopy, 1.3 % in case of non-tumoral lesions, 3.2 % in case of benign tumors, and 11 % in case of premalignant/malignant tumors. These four percentages were not statistically different. The GDS fecal Carriage rate was lower than expected, which did not confirm our working hypothesis. Most strains belonged to S. bovis biotype II, while S. gallolyticus was found only once. These findings suggest that different GDS play different roles in the etiopathogenesis of IE and colorectal cancer.