The Experts below are selected from a list of 28140 Experts worldwide ranked by ideXlab platform
Rastislav Lukac - One of the best experts on this subject based on the ideXlab platform.
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Vector edge operators for cDNA Microarray spot localization.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society, 2007Co-Authors: Rastislav Lukac, Konstantinos N PlataniotisAbstract:This paper introduces a vector-based framework for edge detection and spot localization in cDNA Microarray data. Since cDNA Microarray images can be viewed as vector fields, both their spectral and spatial characteristics should be used to determine edges, discontinuities and structural elements. Building upon the powerful nature of nonlinear operators, the proposed vector edge operators can effectively localize Microarray spots outperforming the commonly used scalar edge detectors. Moreover, due to the utilization of the principle of robust statistics, vector edge detectors are relatively immune to the noise present in Microarray images. Simulation studies reported in this paper indicate that the proposed framework yields excellent performance and it can be readily incorporated in the cDNA Microarray processing pipeline.
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cDNA Microarray imaging using single sensor technology
Canadian Conference on Electrical and Computer Engineering, 2006Co-Authors: Rastislav Lukac, Konstantinos N PlataniotisAbstract:A new solution for cDNA Microarray image acquisition and processing is introduced. The proposed solution uses a two-color filter array placed on top of a single image sensor to capture the two-channel cDNA Microarray data as a single monochromatic image, thus reducing twofold the memory and storage space. The vectorial nature of the cDNA Microarray data is restored using the proposed image processing framework which also denoises and enhances the acquired image.
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CCECE - cDNA Microarray Imaging using Single-Sensor Technology
2006 Canadian Conference on Electrical and Computer Engineering, 2006Co-Authors: Rastislav Lukac, Konstantinos N PlataniotisAbstract:A new solution for cDNA Microarray image acquisition and processing is introduced. The proposed solution uses a two-color filter array placed on top of a single image sensor to capture the two-channel cDNA Microarray data as a single monochromatic image, thus reducing twofold the memory and storage space. The vectorial nature of the cDNA Microarray data is restored using the proposed image processing framework which also denoises and enhances the acquired image.
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cDNA Microarray image segmentation using root signals
International Journal of Imaging Systems and Technology, 2006Co-Authors: Rastislav Lukac, Konstantinos N PlataniotisAbstract:A vector processing based framework suitable for cDNA Microarray image segmentation is introduced and analyzed in this paper. By using nonlinear, generalized selection vector filters the framework proposed here classifies the cDNA image data as either Microarray spots or image background. The solution converges to a root signal that represents the segmented cDNA Microarray image with the regular spots ideally separated from the background and with their coloration uniquely described by dominant color vectors. It will be demonstrated that the framework readily unifies image denoising, enhancement, data normalization, irregular spot rejection, and spot segmentation in one processing step delivering excellent performance at reasonable computational cost. © 2006 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 16, 51–64, 2006
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cDNA Microarray image processing using fuzzy vector filtering framework
Fuzzy Sets and Systems, 2005Co-Authors: Rastislav Lukac, Konstantinos N Plataniotis, Bogdan Smolka, A N VenetsanopoulosAbstract:This paper presents a novel filtering framework capable of processing cDNA Microarray images. The proposed two-component adaptive vector filters integrate well-known concepts from the areas of fuzzy set theory, nonlinear filtering, multidimensional scaling and robust order-statistics. By appropriately setting the weighting coefficients in a generalized framework, the method is capable of removing noise impairments while preserving structural information in cDNA Microarray images. Noise removal is performed by tuning a membership function which utilizes distance criteria applied to cDNA vectorial inputs at each image location. The classical vector representation, adopted here for a two-channel processing task, as well as a new color-ratio model representation are used. Simulation studies reported in this paper indicate that the proposed adaptive fuzzy vector filters are computationally attractive, yield excellent performance and are able to preserve structural information while efficiently suppressing noise in cDNA Microarray data.
Erwin P. Bottinger - One of the best experts on this subject based on the ideXlab platform.
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Genetic/genomic analysis of signal transduction pathways using cDNA Microarray technology
Nature Genetics, 1999Co-Authors: Yaw-ching Yang, Ester Piek, Aldo Massimi, Rongguang Yang, Joerg Heyer, Raju Kucherlapati, Anita B. Roberts, Erwin P. BottingerAbstract:cDNA Microarray technology provides a novel approach to identify individual target genes and survey global genetic programs under the control of specific signalling pathways in mammalian systems. Smad2 and Smad3 are highly homologous members of the receptor-regulated subfamily of Smad proteins with a central role in TGF- signalling and target gene regulation.
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genetic genomic analysis of signal transduction pathways using cDNA Microarray technology
Nature Genetics, 1999Co-Authors: Yaw-ching Yang, Ester Piek, Aldo Massimi, Rongguang Yang, Joerg Heyer, Raju Kucherlapati, Anita B. Roberts, Erwin P. BottingerAbstract:cDNA Microarray technology provides a novel approach to identify individual target genes and survey global genetic programs under the control of specific signalling pathways in mammalian systems. Smad2 and Smad3 are highly homologous members of the receptor-regulated subfamily of Smad proteins with a central role in TGF- signalling and target gene regulation.
Konstantinos N Plataniotis - One of the best experts on this subject based on the ideXlab platform.
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Vector edge operators for cDNA Microarray spot localization.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society, 2007Co-Authors: Rastislav Lukac, Konstantinos N PlataniotisAbstract:This paper introduces a vector-based framework for edge detection and spot localization in cDNA Microarray data. Since cDNA Microarray images can be viewed as vector fields, both their spectral and spatial characteristics should be used to determine edges, discontinuities and structural elements. Building upon the powerful nature of nonlinear operators, the proposed vector edge operators can effectively localize Microarray spots outperforming the commonly used scalar edge detectors. Moreover, due to the utilization of the principle of robust statistics, vector edge detectors are relatively immune to the noise present in Microarray images. Simulation studies reported in this paper indicate that the proposed framework yields excellent performance and it can be readily incorporated in the cDNA Microarray processing pipeline.
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cDNA Microarray imaging using single sensor technology
Canadian Conference on Electrical and Computer Engineering, 2006Co-Authors: Rastislav Lukac, Konstantinos N PlataniotisAbstract:A new solution for cDNA Microarray image acquisition and processing is introduced. The proposed solution uses a two-color filter array placed on top of a single image sensor to capture the two-channel cDNA Microarray data as a single monochromatic image, thus reducing twofold the memory and storage space. The vectorial nature of the cDNA Microarray data is restored using the proposed image processing framework which also denoises and enhances the acquired image.
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CCECE - cDNA Microarray Imaging using Single-Sensor Technology
2006 Canadian Conference on Electrical and Computer Engineering, 2006Co-Authors: Rastislav Lukac, Konstantinos N PlataniotisAbstract:A new solution for cDNA Microarray image acquisition and processing is introduced. The proposed solution uses a two-color filter array placed on top of a single image sensor to capture the two-channel cDNA Microarray data as a single monochromatic image, thus reducing twofold the memory and storage space. The vectorial nature of the cDNA Microarray data is restored using the proposed image processing framework which also denoises and enhances the acquired image.
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cDNA Microarray image segmentation using root signals
International Journal of Imaging Systems and Technology, 2006Co-Authors: Rastislav Lukac, Konstantinos N PlataniotisAbstract:A vector processing based framework suitable for cDNA Microarray image segmentation is introduced and analyzed in this paper. By using nonlinear, generalized selection vector filters the framework proposed here classifies the cDNA image data as either Microarray spots or image background. The solution converges to a root signal that represents the segmented cDNA Microarray image with the regular spots ideally separated from the background and with their coloration uniquely described by dominant color vectors. It will be demonstrated that the framework readily unifies image denoising, enhancement, data normalization, irregular spot rejection, and spot segmentation in one processing step delivering excellent performance at reasonable computational cost. © 2006 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 16, 51–64, 2006
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cDNA Microarray image processing using fuzzy vector filtering framework
Fuzzy Sets and Systems, 2005Co-Authors: Rastislav Lukac, Konstantinos N Plataniotis, Bogdan Smolka, A N VenetsanopoulosAbstract:This paper presents a novel filtering framework capable of processing cDNA Microarray images. The proposed two-component adaptive vector filters integrate well-known concepts from the areas of fuzzy set theory, nonlinear filtering, multidimensional scaling and robust order-statistics. By appropriately setting the weighting coefficients in a generalized framework, the method is capable of removing noise impairments while preserving structural information in cDNA Microarray images. Noise removal is performed by tuning a membership function which utilizes distance criteria applied to cDNA vectorial inputs at each image location. The classical vector representation, adopted here for a two-channel processing task, as well as a new color-ratio model representation are used. Simulation studies reported in this paper indicate that the proposed adaptive fuzzy vector filters are computationally attractive, yield excellent performance and are able to preserve structural information while efficiently suppressing noise in cDNA Microarray data.
Yaw-ching Yang - One of the best experts on this subject based on the ideXlab platform.
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Genetic/genomic analysis of signal transduction pathways using cDNA Microarray technology
Nature Genetics, 1999Co-Authors: Yaw-ching Yang, Ester Piek, Aldo Massimi, Rongguang Yang, Joerg Heyer, Raju Kucherlapati, Anita B. Roberts, Erwin P. BottingerAbstract:cDNA Microarray technology provides a novel approach to identify individual target genes and survey global genetic programs under the control of specific signalling pathways in mammalian systems. Smad2 and Smad3 are highly homologous members of the receptor-regulated subfamily of Smad proteins with a central role in TGF- signalling and target gene regulation.
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genetic genomic analysis of signal transduction pathways using cDNA Microarray technology
Nature Genetics, 1999Co-Authors: Yaw-ching Yang, Ester Piek, Aldo Massimi, Rongguang Yang, Joerg Heyer, Raju Kucherlapati, Anita B. Roberts, Erwin P. BottingerAbstract:cDNA Microarray technology provides a novel approach to identify individual target genes and survey global genetic programs under the control of specific signalling pathways in mammalian systems. Smad2 and Smad3 are highly homologous members of the receptor-regulated subfamily of Smad proteins with a central role in TGF- signalling and target gene regulation.
Aldo Massimi - One of the best experts on this subject based on the ideXlab platform.
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Genetic/genomic analysis of signal transduction pathways using cDNA Microarray technology
Nature Genetics, 1999Co-Authors: Yaw-ching Yang, Ester Piek, Aldo Massimi, Rongguang Yang, Joerg Heyer, Raju Kucherlapati, Anita B. Roberts, Erwin P. BottingerAbstract:cDNA Microarray technology provides a novel approach to identify individual target genes and survey global genetic programs under the control of specific signalling pathways in mammalian systems. Smad2 and Smad3 are highly homologous members of the receptor-regulated subfamily of Smad proteins with a central role in TGF- signalling and target gene regulation.
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genetic genomic analysis of signal transduction pathways using cDNA Microarray technology
Nature Genetics, 1999Co-Authors: Yaw-ching Yang, Ester Piek, Aldo Massimi, Rongguang Yang, Joerg Heyer, Raju Kucherlapati, Anita B. Roberts, Erwin P. BottingerAbstract:cDNA Microarray technology provides a novel approach to identify individual target genes and survey global genetic programs under the control of specific signalling pathways in mammalian systems. Smad2 and Smad3 are highly homologous members of the receptor-regulated subfamily of Smad proteins with a central role in TGF- signalling and target gene regulation.