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Mae O Gordon - One of the best experts on this subject based on the ideXlab platform.

  • Central Corneal Thickness in the Ocular Hypertension Treatment Study (OHTS).
    Ophthalmology, 2020
    Co-Authors: James D Brandt, Julia A Beiser, Michael A Kass, Mae O Gordon
    Abstract:

    Central Corneal Thickness influences intraocular pressure (IOP) measurement. We examined the Central Corneal Thickness of subjects in the Ocular Hypertension Treatment Study (OHTS) and determined if Central Corneal Thickness is related to race. Cross-sectional study. One thousand three hundred one OHTS subjects with Central Corneal Thickness measurements. Central Corneal Thickness was determined with ultrasonic pachymeters of the same make and model at all clinical sites of the OHTS. Correlation of mean Central Corneal Thickness with race, baseline IOP, refraction, age, gender, systemic hypertension, and diabetes. Mean Central Corneal Thickness was 573.0 ± 39.0 μm. Twenty-four percent of the OHTS subjects had Central Corneal Thickness > 600 μm. Mean Central Corneal Thickness for African American subjects (555.7 ± 40.0 μm; n = 318) was 23 μm thinner than for white subjects (579.0 ± 37.0 μm; P < 0.0001). Other factors associated with greater mean Central Corneal Thickness were younger age, female gender, and diabetes. OHTS subjects have thicker corneas than the general population. African American subjects have thinner corneas than white subjects in the study. The effect of Central Corneal Thickness may influence the accuracy of applanation tonometry in the diagnosis, screening, and management of patients with glaucoma and ocular hypertension. Copyright © 2020. Published by Elsevier Inc.

  • Central Corneal Thickness in the Ocular Hypertension Treatment Study (OHTS).
    Ophthalmology, 2001
    Co-Authors: James D Brandt, Julia A Beiser, Michael A Kass, Mae O Gordon
    Abstract:

    Abstract Objective Central Corneal Thickness influences intraocular pressure (IOP) measurement. We examined the Central Corneal Thickness of subjects in the Ocular Hypertension Treatment Study (OHTS) and determined if Central Corneal Thickness is related to race. Design Cross-sectional study. Participants One thousand three hundred one OHTS subjects with Central Corneal Thickness measurements. Intervention Central Corneal Thickness was determined with ultrasonic pachymeters of the same make and model at all clinical sites of the OHTS. Main outcome measures Correlation of mean Central Corneal Thickness with race, baseline IOP, refraction, age, gender, systemic hypertension, and diabetes. Results Mean Central Corneal Thickness was 573.0 ± 39.0 μm. Twenty-four percent of the OHTS subjects had Central Corneal Thickness > 600 μm. Mean Central Corneal Thickness for African American subjects (555.7 ± 40.0 μm; n=318) was 23 μm thinner than for white subjects (579.0 ± 37.0 μm; P Conclusions OHTS subjects have thicker corneas than the general population. African American subjects have thinner corneas than white subjects in the study. The effect of Central Corneal Thickness may influence the accuracy of applanation tonometry in the diagnosis, screening, and management of patients with glaucoma and ocular hypertension.

James D Brandt - One of the best experts on this subject based on the ideXlab platform.

  • Central Corneal Thickness in the Ocular Hypertension Treatment Study (OHTS).
    Ophthalmology, 2020
    Co-Authors: James D Brandt, Julia A Beiser, Michael A Kass, Mae O Gordon
    Abstract:

    Central Corneal Thickness influences intraocular pressure (IOP) measurement. We examined the Central Corneal Thickness of subjects in the Ocular Hypertension Treatment Study (OHTS) and determined if Central Corneal Thickness is related to race. Cross-sectional study. One thousand three hundred one OHTS subjects with Central Corneal Thickness measurements. Central Corneal Thickness was determined with ultrasonic pachymeters of the same make and model at all clinical sites of the OHTS. Correlation of mean Central Corneal Thickness with race, baseline IOP, refraction, age, gender, systemic hypertension, and diabetes. Mean Central Corneal Thickness was 573.0 ± 39.0 μm. Twenty-four percent of the OHTS subjects had Central Corneal Thickness > 600 μm. Mean Central Corneal Thickness for African American subjects (555.7 ± 40.0 μm; n = 318) was 23 μm thinner than for white subjects (579.0 ± 37.0 μm; P < 0.0001). Other factors associated with greater mean Central Corneal Thickness were younger age, female gender, and diabetes. OHTS subjects have thicker corneas than the general population. African American subjects have thinner corneas than white subjects in the study. The effect of Central Corneal Thickness may influence the accuracy of applanation tonometry in the diagnosis, screening, and management of patients with glaucoma and ocular hypertension. Copyright © 2020. Published by Elsevier Inc.

  • Markedly increased Central Corneal Thickness: an unrecognized finding in congenital aniridia☆
    American journal of ophthalmology, 2004
    Co-Authors: James D Brandt, Lourdes A. Casuso, Donald L. Budenz
    Abstract:

    Abstract Purpose To describe Central Corneal Thickness among patients diagnosed with congenital aniridia. Design Prospective noninterventional case series. Methods We identified patients carrying the clinical diagnosis of congenital aniridia and performed complete ophthalmic examinations. Eyes with known Corneal pathology were excluded. Central Corneal Thickness was determined as the mean of five measurements per eye, acquired by matching ultrasonic pachymeters at two clinical sites. Results Seventeen patients were identified at two sites; 32 eyes qualified for inclusion. The average Central Corneal Thickness of the qualifying eyes was 631.6 ± 50.8 μM. Conclusion Markedly increased Central Corneal Thickness appears to be a previously unrecognized aspect of congenital aniridia. This may lead to incorrect estimates of intraocular pressure by applanation techniques and highlights the importance of monitoring patients with aniridia for the development of glaucoma through regular gonioscopy and optic nerve examination.

  • Central Corneal Thickness in the Ocular Hypertension Treatment Study (OHTS).
    Ophthalmology, 2001
    Co-Authors: James D Brandt, Julia A Beiser, Michael A Kass, Mae O Gordon
    Abstract:

    Abstract Objective Central Corneal Thickness influences intraocular pressure (IOP) measurement. We examined the Central Corneal Thickness of subjects in the Ocular Hypertension Treatment Study (OHTS) and determined if Central Corneal Thickness is related to race. Design Cross-sectional study. Participants One thousand three hundred one OHTS subjects with Central Corneal Thickness measurements. Intervention Central Corneal Thickness was determined with ultrasonic pachymeters of the same make and model at all clinical sites of the OHTS. Main outcome measures Correlation of mean Central Corneal Thickness with race, baseline IOP, refraction, age, gender, systemic hypertension, and diabetes. Results Mean Central Corneal Thickness was 573.0 ± 39.0 μm. Twenty-four percent of the OHTS subjects had Central Corneal Thickness > 600 μm. Mean Central Corneal Thickness for African American subjects (555.7 ± 40.0 μm; n=318) was 23 μm thinner than for white subjects (579.0 ± 37.0 μm; P Conclusions OHTS subjects have thicker corneas than the general population. African American subjects have thinner corneas than white subjects in the study. The effect of Central Corneal Thickness may influence the accuracy of applanation tonometry in the diagnosis, screening, and management of patients with glaucoma and ocular hypertension.

M. B. Shields - One of the best experts on this subject based on the ideXlab platform.

  • Central Corneal Thickness in a Puerto Rican population.
    Journal of glaucoma, 2008
    Co-Authors: Carolyn P. Graeber, Marino Blasini Torres, M. B. Shields
    Abstract:

    PURPOSE To evaluate mean Central Corneal Thickness (CCT) in a Puerto Rican population and to compare our findings with published mean Central Corneal Thicknesses of white, Hispanic, and African American populations in the United States. PATIENTS AND METHODS Volunteers at the Centro Medico, San Juan, Puerto Rico, completed a survey and participated in an eye examination, which included measurement of intraocular pressure and Central Corneal Thickness. RESULTS Of 588 Puerto Rican participants, the mean CCT was 541+/-33 microm, which is significantly thinner than the published values for white populations (P

David Zadok - One of the best experts on this subject based on the ideXlab platform.

  • Central Corneal Thickness measurement with the pentacam scheimpflug system optical low coherence reflectometry pachymeter and ultrasound pachymetry
    Journal of Cataract and Refractive Surgery, 2005
    Co-Authors: Yaniv Arkana, Yariv Gerbe, Uri Elbaz, Shulami Schwartz, Gie Kendro, Isaac Avni, David Zadok
    Abstract:

    Purpose To assess the intraoperator repeatability and interoperator reproducibility of Central Corneal Thickness measurements by the Pentacam Scheimpflug imaging system (Oculus) and the optical low-coherence reflectometer (OLCR) pachymeter (Haag-Streit) and to compare them with those of ultrasound (US) pachymetry. Setting Assaf Harofe Medical Center Ophthalmology Outpatient Clinic, Zerifin, Israel. Methods Repeatability was determined from 10 successive measurements in each of 4 healthy patients. Reproducibility for the Pentacam Scheimpflug system was determined from measurements by 2 operators in each of 24 patients; in these 24 patients, Central Corneal Thickness measurements were compared between the Pentacam and US pachymetry. For the OLCR pachymeter, reproducibility was determined from measurements by 2 operators in each of 16 patients, in whom Central Corneal Thickness was also measured with the Pentacam. Results Mean coefficient of repeatability was 0.84% for the Pentacam Scheimpflug system and 0.33% for the OLCR pachymeter. For the Pentacam, the coefficient of interoperator reproducibility was 1.10% and the 95% limits of agreement were −10.2 μm to +11.9 μm. Mean difference between Pentacam and US was 6.09 μm. For the OLCR pachymeter, the coefficient of interoperator reproducibility was 0.59% and the 95% limits of agreement were −5.4 μm to +7.0 μm. Mean difference between Central Corneal Thickness values obtained with the OLCR pachymeter and Pentacam Scheimpflug system was 1.7 μm. Conclusions Objective, noncontact measurement of Central Corneal Thickness with the Pentacam Scheimpflug system and OLCR pachymeter was convenient and yielded excellent intraoperator repeatability and interoperator reproducibility. Central Corneal Thickness values obtained with the Pentacam were similar to those obtained with both the OLCR pachymeter and an US pachymeter. Further research is needed to corroborate whether Central Corneal Thickness measurements by the Pentacam and OLCR devices can be used interchangeably and are more clinically useful than US pachymetry.

Carolyn P. Graeber - One of the best experts on this subject based on the ideXlab platform.

  • Central Corneal Thickness in a Puerto Rican population.
    Journal of glaucoma, 2008
    Co-Authors: Carolyn P. Graeber, Marino Blasini Torres, M. B. Shields
    Abstract:

    PURPOSE To evaluate mean Central Corneal Thickness (CCT) in a Puerto Rican population and to compare our findings with published mean Central Corneal Thicknesses of white, Hispanic, and African American populations in the United States. PATIENTS AND METHODS Volunteers at the Centro Medico, San Juan, Puerto Rico, completed a survey and participated in an eye examination, which included measurement of intraocular pressure and Central Corneal Thickness. RESULTS Of 588 Puerto Rican participants, the mean CCT was 541+/-33 microm, which is significantly thinner than the published values for white populations (P