The Experts below are selected from a list of 201 Experts worldwide ranked by ideXlab platform

E Balfors - One of the best experts on this subject based on the ideXlab platform.

Karl A Franklin - One of the best experts on this subject based on the ideXlab platform.

Xunming Ji - One of the best experts on this subject based on the ideXlab platform.

  • advances in chronic Cerebral Circulation insufficiency
    CNS Neuroscience & Therapeutics, 2018
    Co-Authors: Da Zhou, Ran Meng, Sijie Li, Jingyuan Ya, Jiayue Ding, Shuling Shang, Yuchuan Ding, Xunming Ji
    Abstract:

    Chronic Cerebral Circulation insufficiency (CCCI) may not be an independent disease; rather, it is a pervasive state of long-term Cerebral blood flow insufficiency caused by a variety of etiologies, and considered to be associated with either occurrence or recurrence of ischemic stroke, vascular cognitive impairment, and development of vascular dementia, resulting in disability and mortality worldwide. This review summarizes the features and recent progress of CCCI, mainly focusing on epidemiology, experimental research, pathophysiology, etiology, clinical manifestations, imaging presentation, diagnosis, and potential therapeutic regimens. Some research directions are briefly discussed as well.

Yuchuan Ding - One of the best experts on this subject based on the ideXlab platform.

  • advances in chronic Cerebral Circulation insufficiency
    CNS Neuroscience & Therapeutics, 2018
    Co-Authors: Da Zhou, Ran Meng, Sijie Li, Jingyuan Ya, Jiayue Ding, Shuling Shang, Yuchuan Ding, Xunming Ji
    Abstract:

    Chronic Cerebral Circulation insufficiency (CCCI) may not be an independent disease; rather, it is a pervasive state of long-term Cerebral blood flow insufficiency caused by a variety of etiologies, and considered to be associated with either occurrence or recurrence of ischemic stroke, vascular cognitive impairment, and development of vascular dementia, resulting in disability and mortality worldwide. This review summarizes the features and recent progress of CCCI, mainly focusing on epidemiology, experimental research, pathophysiology, etiology, clinical manifestations, imaging presentation, diagnosis, and potential therapeutic regimens. Some research directions are briefly discussed as well.

Chengyen Chang - One of the best experts on this subject based on the ideXlab platform.

  • stenotic transverse sinus predisposes to poststenting hyperperfusion syndrome as evidenced by quantitative analysis of peritherapeutic Cerebral Circulation time
    American Journal of Neuroradiology, 2014
    Co-Authors: Fengchi Chang, F Y Tsai, Shengche Hung, D Y T Chen, Chengyen Chang
    Abstract:

    BACKGROUND AND PURPOSE: Hyperperfusion syndrome is a devastating complication of carotid stent placement. The shortening of Cerebral Circulation time after stent placement is seen as a good indicator of the development of hyperperfusion syndrome. The purpose of our study was to evaluate whether patients with ipsilateral transverse sinus stenosis are prone to having shortened Cerebral Circulation time after stent placement, subsequently leading to the possible development of hyperperfusion syndrome. MATERIALS AND METHODS: Forty-nine patients with >70% unilateral carotid stenosis undergoing stent placement were recruited for analysis. Group A consisted of patients with a stenotic ipsilateral transverse sinus >50% greater than the diameter of the contralateral transverse sinus; the remaining patients were in group B. Quantitative DSA was used to calculate Cerebral Circulation time. Cerebral Circulation time was defined as the time difference between the relative time to maximal intensity of ROIs in the proximal internal carotid artery and the internal jugular vein. ΔCCT was defined as Cerebral Circulation time before stent placement minus Cerebral Circulation time after stent placement. ΔCCT, white matter hyperintensity signals, and sulcal effacement in MR imaging were compared between the 2 groups. RESULTS: ΔCCT was significantly shorter in group A (0.65 ± 1.3) than in group B (-0.12 ± 1.4). Three patients had white matter hyperintensity signals in group A, and 1 developed hyperperfusion syndrome. Group B showed no MR imaging signs of hyperperfusion syndrome. CONCLUSIONS: Ipsilateral hypoplastic transverse sinus was associated with prolonged Cerebral Circulation time before stent placement and greatly shortened Cerebral Circulation time after stent placement. Inadequate venous drainage might play a role in impaired Cerebral autoregulation and might influence the development of poststenting hyperperfusion syndrome.