The Experts below are selected from a list of 3009 Experts worldwide ranked by ideXlab platform
Bart Van Meerbeek - One of the best experts on this subject based on the ideXlab platform.
-
rechargeable anti microbial adhesive formulation containing Cetylpyridinium Chloride montmorillonite
Acta Biomaterialia, 2019Co-Authors: Kenya Matsuo, Kumiko Yoshihara, Noriyuki Nagaoka, Yoji Makita, Hideki Obika, Takumi Okihara, Akihiro Matsukawa, Yasuhiro Yoshida, Bart Van MeerbeekAbstract:Abstract Long-term anti-bacterial effect is a desired ability of any dental material in combating tooth caries as one of the most common and widespread persistent diseases today. Among several cationic quaternary ammonium compounds with antiseptic properties, Cetylpyridinium Chloride (CPC) is often used in mouthrinses and toothpastes. In this study, we incorporated CPC in a soft phyllosilicate mineral (clay), referred to as montmorillonite (Mont), to enable gradual CPC release with rechargeability. Besides measuring CPC release and recharge, we examined the anti-bacterial effect, cytotoxicity and bonding effectiveness of five experimental adhesive formulations, prepared by adding 1 and 3 wt% CPC_Mont, 3 wt% Mont (without CPC), and 1 and 3 wt% CPC (without Mont) to the commercial adhesive Clearfil S3 Bond ND Quick (‘C-S3B’; Kuraray Noritake). Strong inhibition of Streptococcus mutans biofilm formation by CPC_Mont adhesives was confirmed by optical density and SEM. CPC release from CPC_Mont adhesives was higher and lasted longer than from CPC adhesives, while CPC_Mont adhesives could also be recharged with CPC upon immersion in 2 wt% CPC. In conclusion, CPC_Mont technology rendered adhesives anti-bacterial properties with recharge ability, this without reducing its bonding potential, neither increasing its cytotoxicity. Statement of significance Dental caries is one of the most prevalent chronic diseases in the population worldwide and is the major cause of tooth loss. In this study, we developed Cetylpyridinium Chloride (CPC) loaded montmorillonite (CPC-Mont) with a long-term antibacterial efficacy to prevent caries. CPC is an antibacterial agent approved by FDA, used as an OTC drug and contained in oral hygiene aids. CPC-Mont was incorporated in a dental adhesive to gradually release CPC. CPC_Mont technology rendered adhesives anti-bacterial properties with rechargeability, this without reducing its bonding potential, neither increasing its cytotoxicity.
Kumiko Yoshihara - One of the best experts on this subject based on the ideXlab platform.
-
rechargeable anti microbial adhesive formulation containing Cetylpyridinium Chloride montmorillonite
Acta Biomaterialia, 2019Co-Authors: Kenya Matsuo, Kumiko Yoshihara, Noriyuki Nagaoka, Yoji Makita, Hideki Obika, Takumi Okihara, Akihiro Matsukawa, Yasuhiro Yoshida, Bart Van MeerbeekAbstract:Abstract Long-term anti-bacterial effect is a desired ability of any dental material in combating tooth caries as one of the most common and widespread persistent diseases today. Among several cationic quaternary ammonium compounds with antiseptic properties, Cetylpyridinium Chloride (CPC) is often used in mouthrinses and toothpastes. In this study, we incorporated CPC in a soft phyllosilicate mineral (clay), referred to as montmorillonite (Mont), to enable gradual CPC release with rechargeability. Besides measuring CPC release and recharge, we examined the anti-bacterial effect, cytotoxicity and bonding effectiveness of five experimental adhesive formulations, prepared by adding 1 and 3 wt% CPC_Mont, 3 wt% Mont (without CPC), and 1 and 3 wt% CPC (without Mont) to the commercial adhesive Clearfil S3 Bond ND Quick (‘C-S3B’; Kuraray Noritake). Strong inhibition of Streptococcus mutans biofilm formation by CPC_Mont adhesives was confirmed by optical density and SEM. CPC release from CPC_Mont adhesives was higher and lasted longer than from CPC adhesives, while CPC_Mont adhesives could also be recharged with CPC upon immersion in 2 wt% CPC. In conclusion, CPC_Mont technology rendered adhesives anti-bacterial properties with recharge ability, this without reducing its bonding potential, neither increasing its cytotoxicity. Statement of significance Dental caries is one of the most prevalent chronic diseases in the population worldwide and is the major cause of tooth loss. In this study, we developed Cetylpyridinium Chloride (CPC) loaded montmorillonite (CPC-Mont) with a long-term antibacterial efficacy to prevent caries. CPC is an antibacterial agent approved by FDA, used as an OTC drug and contained in oral hygiene aids. CPC-Mont was incorporated in a dental adhesive to gradually release CPC. CPC_Mont technology rendered adhesives anti-bacterial properties with rechargeability, this without reducing its bonding potential, neither increasing its cytotoxicity.
Fred W. Pohlman - One of the best experts on this subject based on the ideXlab platform.
-
the impact of single antimicrobial intervention treatment with Cetylpyridinium Chloride trisodium phosphate chlorine dioxide or lactic acid on ground beef lipid instrumental color and sensory characteristics
Meat Science, 2003Co-Authors: J R Jimenezvillarreal, Fred W. Pohlman, A H Brown, Z B Johnson, R T BaublitsAbstract:Abstract The effects of antimicrobial agents on ground beef were evaluated to determine if instrumental color, sensory or odor characteristics were impacted. Trimmings were treated with 0.5% Cetylpyridinium Chloride (CPC), 200-ppm chlorine dioxide (CLO), 0.5% lactic acid (LA), 10% trisodium phosphate (TSP), or an untreated control (C). Ground beef made from trimmings with CLO and TSP were similar ( P > 0.05) in L ∗ values to the control; however, samples were redder ( a ∗ ; P P P >0.05) to the control in beef odor intensity until day 3 of display. Therefore, the use of antimicrobial agents on beef trimmings may not adversely affect, and may improve bulk ground beef color and odor characteristics.
-
effects of chlorine dioxide Cetylpyridinium Chloride lactic acid and trisodium phosphate on physical chemical and sensory properties of ground beef
Meat Science, 2003Co-Authors: J R Jimenezvillarreal, Fred W. Pohlman, Z B Johnson, A H BrownAbstract:The impact of beef trimmings treated with either 0.5% Cetylpyridinium Chloride (CPC), 200-ppm chlorine dioxide (CLO), 2% lactic acid (LA) or 10% trisodium phosphate (TSP) and an untreated control (C) prior to grinding, on instrumental color, sensory characteristics, TBARS values, pH and Lee-Kramer shear under simulated retail display were evaluated. Trimmings were ground, pattied and sampled at 0, 1, 2, 3 and 7 days of display. Patties from LA, CPC and CLO treatments were lighter (L*; P<0.05) and TSP patties were redder (a*; P<0.05) than C. Panelists found TSP and CPC patties were similar or superior in beef and off odor to C on days 3 and 7 of display. Therefore, treatment of beef trimmings before grinding with TSP, CPC, CLO or LA may not only improve ground beef safety, but maintain or enhance patty shelf life.
-
reduction of e coli salmonella typhimurium coliforms aerobic bacteria and improvement of ground beef color using trisodium phosphate or Cetylpyridinium Chloride before grinding
Meat Science, 2002Co-Authors: Fred W. Pohlman, K. S. Mcelyea, M R Stivarius, A. L. WaldroupAbstract:Abstract The impact of 10% trisodium phosphate (TSP) or 0.5% Cetylpyridinium Chloride (CPC) applied to beef trimmings either aerobically or under vacuum before grinding on Salmonella typhimurium (ST), Escherichia coli (EC), coliform (CO), aerobic plate count (APC), color and sensory attributes of ground beef through display was studied. For this, beef trimmings were inoculated with ST and EC then treated with either TSP or CPC in vacuum or aerobic conditions. Trimmings were ground, packaged, displayed under simulated retail conditions and sampled on days 0, 1, 2, 3 and 7 for microbial, instrumental color, and sensory color and odor characteristics. Aerobic and vacuum antimicrobial application methods were equally effective (P>0.05) for reducing microorganisms in ground beef. Trisodium phosphate and CPC reduced (P 0.05) ground beef redness (a*), oxymyoglobin stability (630 nm/580 nm) and sensory overall color throughout display without adversely affecting odor characteristics.
Kenya Matsuo - One of the best experts on this subject based on the ideXlab platform.
-
rechargeable anti microbial adhesive formulation containing Cetylpyridinium Chloride montmorillonite
Acta Biomaterialia, 2019Co-Authors: Kenya Matsuo, Kumiko Yoshihara, Noriyuki Nagaoka, Yoji Makita, Hideki Obika, Takumi Okihara, Akihiro Matsukawa, Yasuhiro Yoshida, Bart Van MeerbeekAbstract:Abstract Long-term anti-bacterial effect is a desired ability of any dental material in combating tooth caries as one of the most common and widespread persistent diseases today. Among several cationic quaternary ammonium compounds with antiseptic properties, Cetylpyridinium Chloride (CPC) is often used in mouthrinses and toothpastes. In this study, we incorporated CPC in a soft phyllosilicate mineral (clay), referred to as montmorillonite (Mont), to enable gradual CPC release with rechargeability. Besides measuring CPC release and recharge, we examined the anti-bacterial effect, cytotoxicity and bonding effectiveness of five experimental adhesive formulations, prepared by adding 1 and 3 wt% CPC_Mont, 3 wt% Mont (without CPC), and 1 and 3 wt% CPC (without Mont) to the commercial adhesive Clearfil S3 Bond ND Quick (‘C-S3B’; Kuraray Noritake). Strong inhibition of Streptococcus mutans biofilm formation by CPC_Mont adhesives was confirmed by optical density and SEM. CPC release from CPC_Mont adhesives was higher and lasted longer than from CPC adhesives, while CPC_Mont adhesives could also be recharged with CPC upon immersion in 2 wt% CPC. In conclusion, CPC_Mont technology rendered adhesives anti-bacterial properties with recharge ability, this without reducing its bonding potential, neither increasing its cytotoxicity. Statement of significance Dental caries is one of the most prevalent chronic diseases in the population worldwide and is the major cause of tooth loss. In this study, we developed Cetylpyridinium Chloride (CPC) loaded montmorillonite (CPC-Mont) with a long-term antibacterial efficacy to prevent caries. CPC is an antibacterial agent approved by FDA, used as an OTC drug and contained in oral hygiene aids. CPC-Mont was incorporated in a dental adhesive to gradually release CPC. CPC_Mont technology rendered adhesives anti-bacterial properties with rechargeability, this without reducing its bonding potential, neither increasing its cytotoxicity.
A. L. Waldroup - One of the best experts on this subject based on the ideXlab platform.
-
reduction of e coli salmonella typhimurium coliforms aerobic bacteria and improvement of ground beef color using trisodium phosphate or Cetylpyridinium Chloride before grinding
Meat Science, 2002Co-Authors: Fred W. Pohlman, K. S. Mcelyea, M R Stivarius, A. L. WaldroupAbstract:Abstract The impact of 10% trisodium phosphate (TSP) or 0.5% Cetylpyridinium Chloride (CPC) applied to beef trimmings either aerobically or under vacuum before grinding on Salmonella typhimurium (ST), Escherichia coli (EC), coliform (CO), aerobic plate count (APC), color and sensory attributes of ground beef through display was studied. For this, beef trimmings were inoculated with ST and EC then treated with either TSP or CPC in vacuum or aerobic conditions. Trimmings were ground, packaged, displayed under simulated retail conditions and sampled on days 0, 1, 2, 3 and 7 for microbial, instrumental color, and sensory color and odor characteristics. Aerobic and vacuum antimicrobial application methods were equally effective (P>0.05) for reducing microorganisms in ground beef. Trisodium phosphate and CPC reduced (P 0.05) ground beef redness (a*), oxymyoglobin stability (630 nm/580 nm) and sensory overall color throughout display without adversely affecting odor characteristics.