The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

A E Kark - One of the best experts on this subject based on the ideXlab platform.

  • infusion Cholecystography in the diagnosis of acute cholecystitis
    British Journal of Surgery, 2005
    Co-Authors: D J Pinto, M Burke, R A Wilkins, A E Kark
    Abstract:

    The use of infusion Cholecystography as an aid in the diagnosis of acute cholecystitis was investigated in 21 patients. Seventeen of 18 patients (94 per cent) with positive cholecyst-tomograms who underwent laparotomy had confirmation of acutely inflamed gallbladders both macroscopically and histologically. These findings suggest that infusion Cholecystography can make a significant contribution in reducing the incidence of misdiagnosis in acute cholecystitis, and that the investigation should be part of the management of patients in whom early surgery is planned.

C S Mcardle - One of the best experts on this subject based on the ideXlab platform.

  • infusion Cholecystography in the early diagnosis of acute gallbladder disease
    British Journal of Surgery, 2005
    Co-Authors: Evelyn H Dykes, I Stewart, H W Gray, C Simpson, S Davidson, C S Mcardle
    Abstract:

    The value of infusion Cholecystography 99mTc HIDA cholescintigraphy and ultrasonography was compared in 51 patients presenting with a clinical diagnosis of acute cholecystitis. Of the 35 patients with proven gallbladder disease, the presence of gallstones was correctly predicted in 31 (88 per cent) by infusion Cholecystography, 32 (90 per cent) by 99mTc HIDA cholescintigraphy and 27 (77 per cent) by ultrasonography. There were no false positive investigations. Infusion Cholecystography may be of particular interest to surgeons with no ready access to isotope scanning techniques.

D J Pinto - One of the best experts on this subject based on the ideXlab platform.

  • infusion Cholecystography in the diagnosis of acute cholecystitis
    British Journal of Surgery, 2005
    Co-Authors: D J Pinto, M Burke, R A Wilkins, A E Kark
    Abstract:

    The use of infusion Cholecystography as an aid in the diagnosis of acute cholecystitis was investigated in 21 patients. Seventeen of 18 patients (94 per cent) with positive cholecyst-tomograms who underwent laparotomy had confirmation of acutely inflamed gallbladders both macroscopically and histologically. These findings suggest that infusion Cholecystography can make a significant contribution in reducing the incidence of misdiagnosis in acute cholecystitis, and that the investigation should be part of the management of patients in whom early surgery is planned.

Evelyn H Dykes - One of the best experts on this subject based on the ideXlab platform.

  • infusion Cholecystography in the early diagnosis of acute gallbladder disease
    British Journal of Surgery, 2005
    Co-Authors: Evelyn H Dykes, I Stewart, H W Gray, C Simpson, S Davidson, C S Mcardle
    Abstract:

    The value of infusion Cholecystography 99mTc HIDA cholescintigraphy and ultrasonography was compared in 51 patients presenting with a clinical diagnosis of acute cholecystitis. Of the 35 patients with proven gallbladder disease, the presence of gallstones was correctly predicted in 31 (88 per cent) by infusion Cholecystography, 32 (90 per cent) by 99mTc HIDA cholescintigraphy and 27 (77 per cent) by ultrasonography. There were no false positive investigations. Infusion Cholecystography may be of particular interest to surgeons with no ready access to isotope scanning techniques.

E A Shaffer - One of the best experts on this subject based on the ideXlab platform.

  • efficacy of bile acid therapy for gallstone dissolution a meta analysis of randomized trials
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: G R May, Lloyd R Sutherland, E A Shaffer
    Abstract:

    To define better the efficacy of bile acid therapy for dissolution of radiolucent gallstones, we performed a meta-analysis of published trials from January 1966 to September 1992. Studies were identified using a MEDLINE computer search followed by an extensive manual search. The inclusion criteria used were: randomized trial, radiolucent gallstones in a visualizing gallbladder on oral Cholecystography, and complete stone dissolution confirmed by oral Cholecystography or ultrasound. Study results were pooled into 6 groups: placebo: high- and low-dose chenodeoxycholic acid (CDCA) (> or = 10 mg.kg/day and or = 7 mg.kg/day and 6 months' duration, high-dose UDCA completely dissolved stones in 37.3% of patients (95% C.I. 33-42%), low-dose UDCA in 20.6%) and high-dose CDCA 18.2% (95% C.I. 15-21%). Based on only two studies, combination therapy achieved dissolution in 62.8% (95% C.I. 51-74%) of patients. Stones less than 10 mm dissolved significantly more frequently than stones larger than 10 mm. This analysis shows that UDCA in doses greater than 7 mg.kg/day taken for greater than 6 months will dissolve radiolucent gallstones in 38% of patients. The combination of UDCA and CDCA may be more efficacious but this observation is based upon only 78 patients and requires confirmation in further randomized trials.