The Experts below are selected from a list of 207 Experts worldwide ranked by ideXlab platform

Z Lele - One of the best experts on this subject based on the ideXlab platform.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-3
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    During the Chordamesoderm to mature NC transition step (). (, : 7 hpf; , : 12 hpf; 24 hpf.) This pattern of developmental arrest occurs in (, ), (, ), (, ) and (, ) expression. : mRNA levels of (, ), (, ), (, ) and (, ) however decreases normally upon Chordamesoderm to mature NC transition. Notice the unchanged expression of marker genes in the floor plate () and in the hypochord (, , ) of U0126-treated embryos. Panels: , , , , , , , , , , , : wild type. Panels: , , , , , , , , , , , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-6
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Os. : Expression of the notochordal marker genes () and () also show different defects in SU5402 and U0126-treated embryos. : Expression of (, ) and () is not decreased normally by U0126-treatment. , : mRNA persists and is not downregulated by U0126-treatment.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-4
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Of intersomitic vessels. Notice that both lack of sprouting (yellow arrows) and double sprouting (red arrow) occurs in U0126-treated embryos (). Expression of the early muscle differentiation marker is normal in treated embryos (, ) but the muscle pioneer cell marker is upregulated (, ). The floor plate of the neural tube differentiates normally (, and also ). expression shows that the sensory Rohon-Beard neurons and motoneurons both develop properly in treated embryos (, )Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-1
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-8
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

Thomas A Hawkins - One of the best experts on this subject based on the ideXlab platform.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-3
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    During the Chordamesoderm to mature NC transition step (). (, : 7 hpf; , : 12 hpf; 24 hpf.) This pattern of developmental arrest occurs in (, ), (, ), (, ) and (, ) expression. : mRNA levels of (, ), (, ), (, ) and (, ) however decreases normally upon Chordamesoderm to mature NC transition. Notice the unchanged expression of marker genes in the floor plate () and in the hypochord (, , ) of U0126-treated embryos. Panels: , , , , , , , , , , , : wild type. Panels: , , , , , , , , , , , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-6
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Os. : Expression of the notochordal marker genes () and () also show different defects in SU5402 and U0126-treated embryos. : Expression of (, ) and () is not decreased normally by U0126-treatment. , : mRNA persists and is not downregulated by U0126-treatment.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-4
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Of intersomitic vessels. Notice that both lack of sprouting (yellow arrows) and double sprouting (red arrow) occurs in U0126-treated embryos (). Expression of the early muscle differentiation marker is normal in treated embryos (, ) but the muscle pioneer cell marker is upregulated (, ). The floor plate of the neural tube differentiates normally (, and also ). expression shows that the sensory Rohon-Beard neurons and motoneurons both develop properly in treated embryos (, )Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-1
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-8
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

Gábor Szabó - One of the best experts on this subject based on the ideXlab platform.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-3
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    During the Chordamesoderm to mature NC transition step (). (, : 7 hpf; , : 12 hpf; 24 hpf.) This pattern of developmental arrest occurs in (, ), (, ), (, ) and (, ) expression. : mRNA levels of (, ), (, ), (, ) and (, ) however decreases normally upon Chordamesoderm to mature NC transition. Notice the unchanged expression of marker genes in the floor plate () and in the hypochord (, , ) of U0126-treated embryos. Panels: , , , , , , , , , , , : wild type. Panels: , , , , , , , , , , , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-6
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Os. : Expression of the notochordal marker genes () and () also show different defects in SU5402 and U0126-treated embryos. : Expression of (, ) and () is not decreased normally by U0126-treatment. , : mRNA persists and is not downregulated by U0126-treatment.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-4
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Of intersomitic vessels. Notice that both lack of sprouting (yellow arrows) and double sprouting (red arrow) occurs in U0126-treated embryos (). Expression of the early muscle differentiation marker is normal in treated embryos (, ) but the muscle pioneer cell marker is upregulated (, ). The floor plate of the neural tube differentiates normally (, and also ). expression shows that the sensory Rohon-Beard neurons and motoneurons both develop properly in treated embryos (, )Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-1
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-8
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

Ferenc Erdélyi - One of the best experts on this subject based on the ideXlab platform.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-3
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    During the Chordamesoderm to mature NC transition step (). (, : 7 hpf; , : 12 hpf; 24 hpf.) This pattern of developmental arrest occurs in (, ), (, ), (, ) and (, ) expression. : mRNA levels of (, ), (, ), (, ) and (, ) however decreases normally upon Chordamesoderm to mature NC transition. Notice the unchanged expression of marker genes in the floor plate () and in the hypochord (, , ) of U0126-treated embryos. Panels: , , , , , , , , , , , : wild type. Panels: , , , , , , , , , , , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-6
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Os. : Expression of the notochordal marker genes () and () also show different defects in SU5402 and U0126-treated embryos. : Expression of (, ) and () is not decreased normally by U0126-treatment. , : mRNA persists and is not downregulated by U0126-treatment.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-4
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Of intersomitic vessels. Notice that both lack of sprouting (yellow arrows) and double sprouting (red arrow) occurs in U0126-treated embryos (). Expression of the early muscle differentiation marker is normal in treated embryos (, ) but the muscle pioneer cell marker is upregulated (, ). The floor plate of the neural tube differentiates normally (, and also ). expression shows that the sensory Rohon-Beard neurons and motoneurons both develop properly in treated embryos (, )Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-1
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-8
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

Florencia Cavodeassi - One of the best experts on this subject based on the ideXlab platform.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-3
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    During the Chordamesoderm to mature NC transition step (). (, : 7 hpf; , : 12 hpf; 24 hpf.) This pattern of developmental arrest occurs in (, ), (, ), (, ) and (, ) expression. : mRNA levels of (, ), (, ), (, ) and (, ) however decreases normally upon Chordamesoderm to mature NC transition. Notice the unchanged expression of marker genes in the floor plate () and in the hypochord (, , ) of U0126-treated embryos. Panels: , , , , , , , , , , , : wild type. Panels: , , , , , , , , , , , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-6
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Os. : Expression of the notochordal marker genes () and () also show different defects in SU5402 and U0126-treated embryos. : Expression of (, ) and () is not decreased normally by U0126-treatment. , : mRNA persists and is not downregulated by U0126-treatment.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-4
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Of intersomitic vessels. Notice that both lack of sprouting (yellow arrows) and double sprouting (red arrow) occurs in U0126-treated embryos (). Expression of the early muscle differentiation marker is normal in treated embryos (, ) but the muscle pioneer cell marker is upregulated (, ). The floor plate of the neural tube differentiates normally (, and also ). expression shows that the sensory Rohon-Beard neurons and motoneurons both develop properly in treated embryos (, )Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-1
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.

  • The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish-8
    2011
    Co-Authors: Thomas A Hawkins, Florencia Cavodeassi, Ferenc Erdélyi, Gábor Szabó, Z Lele
    Abstract:

    Igmentation including in the RPE in the eye (compare panels and ), twists and undulations in the NC are already evident at 24 hpf. (, ) and the trunk and tail of treated embryos is shortened at 48 hpf (compare panels and ). The large yolk sac in 48 hpf embryos indicates that circulation is not established properly to carry away its content (see also later in Fig. 5) Panels , : wild type embryos. Panels , : U0126-treated embryos.Copyright information:Taken from "The small molecule Mek1/2 inhibitor U0126 disrupts the Chordamesoderm to notochord transition in zebrafish"http://www.biomedcentral.com/1471-213X/8/42BMC Developmental Biology 2008;8():42-42.Published online 17 Apr 2008PMCID:PMC2359734.