The Experts below are selected from a list of 4536 Experts worldwide ranked by ideXlab platform
Richard Poetter - One of the best experts on this subject based on the ideXlab platform.
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Local Tumor Control, Visual Acuity, and Survival After Hypofractionated Stereotactic Photon Radiotherapy of Choroidal Melanoma in 212 Patients Treated Between 1997 and 2007
International journal of radiation oncology biology physics, 2010Co-Authors: Roman Dunavoelgyi, Karin Dieckmann, Andreas Gleiss, Stefan Sacu, Karl Kircher, Michael Georgopoulos, Dietmar Georg, Martin Zehetmayer, Richard PoetterAbstract:Purpose To evaluate long-term local tumor control, visual acuity, and survival after hypofractionated linear accelerator–based stereotactic photon radiotherapy in patients with Choroidal melanoma. Methods and Materials Between 1997 and 2007, 212 patients with Choroidal melanoma unsuitable for ruthenium-106 brachytherapy or local resection were treated stereotactically at a linear accelerator with 6-MV photon beams at the Medical University of Vienna in five fractions over 7 days. Twenty-four patients received a total dose of 70 Gy (five fractions of 14 Gy), 158 a total dose of 60 Gy (five fractions of 12 Gy) and 30 patients a total dose of 50 Gy (five fractions of 10 Gy) applied on the 80% isodose. Ophthalmologic examinations were performed at baseline and every 3 months in the first 2 years, every 6 months until 5 years, and once a year thereafter until 10 years after radiotherapy. Assessment of visual acuity, routine ophthalmologic examinations, and measurement of tumor base dimension and height using standardized A-scan and B-scan echography were done at each visit. Funduscopy and fluorescein angiography were done when necessary to document tumor response. Results Median tumor height and volume decreased from 4.8 mm and 270.7 mm 3 at baseline to 2.6 mm and 86.6 mm 3 at the last individual follow-up, respectively ( p p p Conclusion Hypofractionated stereotactic photon radiotherapy with 70 to 50 Gy delivered in five fractions in 7 days is sufficient to achieve excellent local tumor control in patients with malignant melanoma of the Choroid. Disease outcome and vision are comparable to those achieved with proton beam radiotherapy. Decreasing the total dose below 60 Gy seems to be possible.
Roman Dunavoelgyi - One of the best experts on this subject based on the ideXlab platform.
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Local Tumor Control, Visual Acuity, and Survival After Hypofractionated Stereotactic Photon Radiotherapy of Choroidal Melanoma in 212 Patients Treated Between 1997 and 2007
International journal of radiation oncology biology physics, 2010Co-Authors: Roman Dunavoelgyi, Karin Dieckmann, Andreas Gleiss, Stefan Sacu, Karl Kircher, Michael Georgopoulos, Dietmar Georg, Martin Zehetmayer, Richard PoetterAbstract:Purpose To evaluate long-term local tumor control, visual acuity, and survival after hypofractionated linear accelerator–based stereotactic photon radiotherapy in patients with Choroidal melanoma. Methods and Materials Between 1997 and 2007, 212 patients with Choroidal melanoma unsuitable for ruthenium-106 brachytherapy or local resection were treated stereotactically at a linear accelerator with 6-MV photon beams at the Medical University of Vienna in five fractions over 7 days. Twenty-four patients received a total dose of 70 Gy (five fractions of 14 Gy), 158 a total dose of 60 Gy (five fractions of 12 Gy) and 30 patients a total dose of 50 Gy (five fractions of 10 Gy) applied on the 80% isodose. Ophthalmologic examinations were performed at baseline and every 3 months in the first 2 years, every 6 months until 5 years, and once a year thereafter until 10 years after radiotherapy. Assessment of visual acuity, routine ophthalmologic examinations, and measurement of tumor base dimension and height using standardized A-scan and B-scan echography were done at each visit. Funduscopy and fluorescein angiography were done when necessary to document tumor response. Results Median tumor height and volume decreased from 4.8 mm and 270.7 mm 3 at baseline to 2.6 mm and 86.6 mm 3 at the last individual follow-up, respectively ( p p p Conclusion Hypofractionated stereotactic photon radiotherapy with 70 to 50 Gy delivered in five fractions in 7 days is sufficient to achieve excellent local tumor control in patients with malignant melanoma of the Choroid. Disease outcome and vision are comparable to those achieved with proton beam radiotherapy. Decreasing the total dose below 60 Gy seems to be possible.
Karin Dieckmann - One of the best experts on this subject based on the ideXlab platform.
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Local Tumor Control, Visual Acuity, and Survival After Hypofractionated Stereotactic Photon Radiotherapy of Choroidal Melanoma in 212 Patients Treated Between 1997 and 2007
International journal of radiation oncology biology physics, 2010Co-Authors: Roman Dunavoelgyi, Karin Dieckmann, Andreas Gleiss, Stefan Sacu, Karl Kircher, Michael Georgopoulos, Dietmar Georg, Martin Zehetmayer, Richard PoetterAbstract:Purpose To evaluate long-term local tumor control, visual acuity, and survival after hypofractionated linear accelerator–based stereotactic photon radiotherapy in patients with Choroidal melanoma. Methods and Materials Between 1997 and 2007, 212 patients with Choroidal melanoma unsuitable for ruthenium-106 brachytherapy or local resection were treated stereotactically at a linear accelerator with 6-MV photon beams at the Medical University of Vienna in five fractions over 7 days. Twenty-four patients received a total dose of 70 Gy (five fractions of 14 Gy), 158 a total dose of 60 Gy (five fractions of 12 Gy) and 30 patients a total dose of 50 Gy (five fractions of 10 Gy) applied on the 80% isodose. Ophthalmologic examinations were performed at baseline and every 3 months in the first 2 years, every 6 months until 5 years, and once a year thereafter until 10 years after radiotherapy. Assessment of visual acuity, routine ophthalmologic examinations, and measurement of tumor base dimension and height using standardized A-scan and B-scan echography were done at each visit. Funduscopy and fluorescein angiography were done when necessary to document tumor response. Results Median tumor height and volume decreased from 4.8 mm and 270.7 mm 3 at baseline to 2.6 mm and 86.6 mm 3 at the last individual follow-up, respectively ( p p p Conclusion Hypofractionated stereotactic photon radiotherapy with 70 to 50 Gy delivered in five fractions in 7 days is sufficient to achieve excellent local tumor control in patients with malignant melanoma of the Choroid. Disease outcome and vision are comparable to those achieved with proton beam radiotherapy. Decreasing the total dose below 60 Gy seems to be possible.
Andreas Gleiss - One of the best experts on this subject based on the ideXlab platform.
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Local Tumor Control, Visual Acuity, and Survival After Hypofractionated Stereotactic Photon Radiotherapy of Choroidal Melanoma in 212 Patients Treated Between 1997 and 2007
International journal of radiation oncology biology physics, 2010Co-Authors: Roman Dunavoelgyi, Karin Dieckmann, Andreas Gleiss, Stefan Sacu, Karl Kircher, Michael Georgopoulos, Dietmar Georg, Martin Zehetmayer, Richard PoetterAbstract:Purpose To evaluate long-term local tumor control, visual acuity, and survival after hypofractionated linear accelerator–based stereotactic photon radiotherapy in patients with Choroidal melanoma. Methods and Materials Between 1997 and 2007, 212 patients with Choroidal melanoma unsuitable for ruthenium-106 brachytherapy or local resection were treated stereotactically at a linear accelerator with 6-MV photon beams at the Medical University of Vienna in five fractions over 7 days. Twenty-four patients received a total dose of 70 Gy (five fractions of 14 Gy), 158 a total dose of 60 Gy (five fractions of 12 Gy) and 30 patients a total dose of 50 Gy (five fractions of 10 Gy) applied on the 80% isodose. Ophthalmologic examinations were performed at baseline and every 3 months in the first 2 years, every 6 months until 5 years, and once a year thereafter until 10 years after radiotherapy. Assessment of visual acuity, routine ophthalmologic examinations, and measurement of tumor base dimension and height using standardized A-scan and B-scan echography were done at each visit. Funduscopy and fluorescein angiography were done when necessary to document tumor response. Results Median tumor height and volume decreased from 4.8 mm and 270.7 mm 3 at baseline to 2.6 mm and 86.6 mm 3 at the last individual follow-up, respectively ( p p p Conclusion Hypofractionated stereotactic photon radiotherapy with 70 to 50 Gy delivered in five fractions in 7 days is sufficient to achieve excellent local tumor control in patients with malignant melanoma of the Choroid. Disease outcome and vision are comparable to those achieved with proton beam radiotherapy. Decreasing the total dose below 60 Gy seems to be possible.
Stefan Sacu - One of the best experts on this subject based on the ideXlab platform.
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Local Tumor Control, Visual Acuity, and Survival After Hypofractionated Stereotactic Photon Radiotherapy of Choroidal Melanoma in 212 Patients Treated Between 1997 and 2007
International journal of radiation oncology biology physics, 2010Co-Authors: Roman Dunavoelgyi, Karin Dieckmann, Andreas Gleiss, Stefan Sacu, Karl Kircher, Michael Georgopoulos, Dietmar Georg, Martin Zehetmayer, Richard PoetterAbstract:Purpose To evaluate long-term local tumor control, visual acuity, and survival after hypofractionated linear accelerator–based stereotactic photon radiotherapy in patients with Choroidal melanoma. Methods and Materials Between 1997 and 2007, 212 patients with Choroidal melanoma unsuitable for ruthenium-106 brachytherapy or local resection were treated stereotactically at a linear accelerator with 6-MV photon beams at the Medical University of Vienna in five fractions over 7 days. Twenty-four patients received a total dose of 70 Gy (five fractions of 14 Gy), 158 a total dose of 60 Gy (five fractions of 12 Gy) and 30 patients a total dose of 50 Gy (five fractions of 10 Gy) applied on the 80% isodose. Ophthalmologic examinations were performed at baseline and every 3 months in the first 2 years, every 6 months until 5 years, and once a year thereafter until 10 years after radiotherapy. Assessment of visual acuity, routine ophthalmologic examinations, and measurement of tumor base dimension and height using standardized A-scan and B-scan echography were done at each visit. Funduscopy and fluorescein angiography were done when necessary to document tumor response. Results Median tumor height and volume decreased from 4.8 mm and 270.7 mm 3 at baseline to 2.6 mm and 86.6 mm 3 at the last individual follow-up, respectively ( p p p Conclusion Hypofractionated stereotactic photon radiotherapy with 70 to 50 Gy delivered in five fractions in 7 days is sufficient to achieve excellent local tumor control in patients with malignant melanoma of the Choroid. Disease outcome and vision are comparable to those achieved with proton beam radiotherapy. Decreasing the total dose below 60 Gy seems to be possible.