The Experts below are selected from a list of 252 Experts worldwide ranked by ideXlab platform
J Crino - One of the best experts on this subject based on the ideXlab platform.
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Choroid Plexus Cysts do not affect fetal neurodevelopment
Journal of Perinatology, 2006Co-Authors: J A Dipietro, K A Costigan, E A Cristofalo, Y Lu, C W Bird, C A Mcshane, J CrinoAbstract:Objective: To determine whether an isolated finding of a Choroid Plexus Cyst (CPC) during routine ultrasound is associated with altered fetal growth or development. Study design: Prospective, case–control study comparing 35 CPC cases to 67 controls. Neurobehavioral development assessment included 50 min long serial recordings of heart rate, motor activity and their interrelation at 24, 28, 32 and 36 weeks gestation. Growth measurement was based on three ultrasound evaluations of femur length, biparietal diameter, head circumference and abdominal circumference at initial exam, 28 and 36 weeks. Results: Longitudinal analyses revealed no differences in fetal heart rate, variability or accelerations; the number or duration of fetal movements or total motor activity; nor fetal movement-fetal heart rate coupling. CPC cases had slightly smaller head and abdominal circumferences at 28 weeks, but these differences had disappeared by 36 weeks. CPC detection was more common when routine exams were conducted earlier (18.8 versus 19.5 weeks; P
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Women's response to fetal Choroid Plexus Cysts detected by prenatal ultrasound
Journal of Perinatology, 2006Co-Authors: E A Cristofalo, J A Dipietro, K A Costigan, P Nelson, J CrinoAbstract:Objectives: To determine maternal responses to detection of a minor structural variant, the Choroid Plexus Cyst (CPC), in their fetus on prenatal ultrasound. Study design: We interviewed 34 pregnant women with an isolated CPC detected on mid-pregnancy ultrasound about their objective experience at diagnosis, emotional response and subsequent reactions. Audiotaped, transcribed responses were evaluated by two independent raters and analyzed qualitatively and quantitatively. Results: All women reported negative emotional responses including shock, distress, fear and decreased attachment, despite counseling by 82% of providers that the CPC was probably benign. Three women underwent amniocentesis purely for reassurance after CPC detection. Most (79%) sought information beyond what their physician provided, frequently on the internet. One half of women reported that intense negative responses were temporary. However, weeks after diagnosis, 62% continued to believe that the CPC presented some danger to their baby. Conclusions: Detection of CPC prenatally can evoke profound, negative maternal emotional responses despite accurate provider counseling. Practitioners should consider these responses when counseling parents about these and other structural variants of unclear functional significance. Sponsor: The Thomas Wilson Sanitarium for the Children of Baltimore City.
Lisa M Korst - One of the best experts on this subject based on the ideXlab platform.
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the isolated Choroid Plexus Cyst
Obstetrics & Gynecology, 1998Co-Authors: Carol L Morcos, Lawrence D Platt, Dru E Carlson, Kimberly D Gregory, Naomi Greene, Lisa M KorstAbstract:Abstract Objective: To describe the karyotypes of a population of fetuses with Choroid Plexus Cysts and compare affected fetuses with and without additional ultrasonographic findings. Methods: The study population included all patients undergoing second-trimester ultrasound examination in a prenatal diagnostic program between January 1993 and October 1995. The records of all cases in which a Choroid Plexus Cyst was found were reviewed, and information was abstracted regarding the fetal karyotype and the presence of other sonographic abnormalities. Results: Two hundred ten cases of Choroid Plexus Cysts were identified among 7617 patients (2.8%) who underwent second-trimester ultrasound examination. The majority of the cases (181, or 86%) involved isolated Choroid Plexus Cysts and the remaining 29 (14%) were associated with additional ultrasonographic findings. Autosomal aneuploidy was found in one patient with an isolated Choroid Plexus Cyst (trisomy 21) and in another with additional findings (trisomy 18); the mothers of both of these patients were at least 35 years old. For those fetuses with known outcome, the risk of aneuploidy with isolated Choroid Plexus Cyst (one in 180) was not statistically significantly different from that associated with Choroid Plexus Cyst accompanied by other sonographic findings (one in 26). More than 1000 fetuses with Choroid Plexus Cysts would have to be studied to determine whether such a difference was real. Conclusion: Because of the rarity of aneuploidy, the reported risk for a fetus with an isolated Choroid Plexus Cyst must be interpreted cautiously and should include the baseline risk.
Edward R Smith - One of the best experts on this subject based on the ideXlab platform.
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Acute hydrocephalus secondary to obstruction of the foramen of monro and cerebral aqueduct caused by a Choroid Plexus Cyst in the lateral ventricle. Case report.
Journal of neurosurgery, 2020Co-Authors: Brian V Nahed, Aneela Darbar, Robert Doiron, Ali Saad, Caroline D Robson, Edward R SmithAbstract:Choroid Plexus Cysts are common and typically asymptomatic abnormal folds of the epithelial lining of the Choroid Plexus. Rarely, these Cysts may gradually enlarge and cause outflow obstruction of cerebrospinal fluid. The authors present a case of a large Choroid Plexus Cyst causing acute hydrocephalus in a previously healthy 2-year-old boy. The patient presented with markedly declining mental status, vomiting, and bradycardia over the course of several hours. Computed tomography scans demonstrated enlarged lateral and third ventricles with sulcal effacement, but no obvious mass lesions or hemorrhage. There was no antecedent illness or trauma. A right frontal external ventricular drain was placed in the patient, resulting in decompression of only the right lateral ventricle. Magnetic resonance (MR) imaging demonstrated a lobulated Cyst arising from the Choroid Plexus of the left lateral ventricle and herniating through the foramen of Monro into the third ventricle, occluding both the foramen of Monro and the cerebral aqueduct. The patient underwent an endoscopic fenestration of the Cyst, and histological results confirmed that it was a Choroid Plexus Cyst. Postoperative MR imaging showed a marked reduction in the Cyst size. The Cyst was no longer in the third ventricle, the foramen of Monro and the aqueduct were patent, and the ventricles were decompressed. The patient was discharged home with no deficits. To the authors' knowledge, there are no previous reports of a Choroid Plexus Cyst causing acute hydrocephalus due to herniation into the third ventricle. This case is illustrative because it describes this entity for the first time, and more importantly highlights the need to obtain a diagnosis when a patient presents with acute hydrocephalus without a clear cause.
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acute hydrocephalus secondary to obstruction of the foramen of monro and cerebral aqueduct caused by a Choroid Plexus Cyst in the lateral ventricle case report
Journal of Neurosurgery, 2007Co-Authors: Brian V Nahed, Aneela Darbar, Robert Doiron, Ali Saad, Caroline D Robson, Edward R SmithAbstract:✓Choroid Plexus Cysts are common and typically asymptomatic abnormal folds of the epithelial lining of the Choroid Plexus. Rarely, these Cysts may gradually enlarge and cause outflow obstruction of cerebrospinal fluid. The authors present a case of a large Choroid Plexus Cyst causing acute hydrocephalus in a previously healthy 2-year-old boy. The patient presented with markedly declining mental status, vomiting, and bradycardia over the course of several hours. Computed tomography scans demonstrated enlarged lateral and third ventricles with sulcal effacement, but no obvious mass lesions or hemorrhage. There was no antecedent illness or trauma. A right frontal external ventricular drain was placed in the patient, resulting in decompression of only the right lateral ventricle. Magnetic resonance (MR) imaging demonstrated a lobulated Cyst arising from the Choroid Plexus of the left lateral ventricle and herniating through the foramen of Monro into the third ventricle, occluding both the foramen of Monro and...
Sharon Chan - One of the best experts on this subject based on the ideXlab platform.
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isolated Choroid Plexus Cyst or echogenic cardiac focus on prenatal ultrasound is genetic amniocentesis indicated
American Journal of Obstetrics and Gynecology, 2007Co-Authors: Joseph G Ouzounian, Carlyne Ludington, Sharon ChanAbstract:Objective The purpose of this study was to determine whether or not genetic amniocentesis is warranted when isolated Choroid Plexus Cysts (CPC) or echogenic cardiac foci (EF) are noted on prenatal ultrasound. Study Design We performed a retrospective analysis on patients from our perinatal database. All obstetric patients with CPC or EF noted on second-trimester perinatology ultrasound from April, 1998 to November, 2004 were included. Information regarding ultrasound findings and neonatal outcome were analyzed. Results During the study period, 515 patients with CPC or EF were evaluated. Of these, 429 (83.3%) had isolated CPC or EF and 86 (16.7%) had additional risk factors. The incidence of abnormal karyotype was 0 versus 2.3%, respectively (P = .03). The additional risk factors considered were: advanced maternal age, abnormal serum triple marker screening, and/or other abnormal ultrasound findings. Furthermore, during the study period there were 20,122 live births and 27 (0.1%) cases of aneuploidy diagnosed postnatally. Of these, none had isolated CPC or EF on prenatal ultrasound. Conclusion CPC or EF noted on prenatal ultrasound warrants referral for careful consultative ultrasound evaluation. In the absence of other risk factors, however, genetic amniocentesis for isolated CPC or EF does not appear to be necessary.
G Mielke - One of the best experts on this subject based on the ideXlab platform.
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clinically significant persistence and enlargement of an antenatally diagnosed isolated Choroid Plexus Cyst
Ultrasound in Obstetrics & Gynecology, 2002Co-Authors: S Becker, G Niemann, M Schoning, D Wallwiener, G MielkeAbstract:Isolated Choroid Plexus Cysts are usually diagnosed at the time of screening ultrasonography during the second trimester. While they raise the question of underlying chromosomal abnormalities, their clinical course is almost invariably benign with complete resolution often by the third trimester. We report the highly unusual case of a Choroid Plexus Cyst diagnosed at 14 weeks of gestational age with subsequent further enlargement of the Cyst, necessitating postpartum neurosurgical intervention.