The Experts below are selected from a list of 57 Experts worldwide ranked by ideXlab platform
Michael H. Foerster - One of the best experts on this subject based on the ideXlab platform.
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Transscleral resection of a Ciliary Body leiomyoma in a child: case report and review of the literature
Graefe's Archive for Clinical and Experimental Ophthalmology, 2003Co-Authors: Miriam N. Richter, Nikolaos E. Bechrakis, G. Stoltenburg-didinger, Michael H. FoersterAbstract:Purpose To present the case of a patient with leiomyoma of the Ciliary Body and discuss the histological features and treatment of this rare intraocular Tumor. Methods/case report A 13-year-old boy presented with an asymptomatic Tumor of the right eye. Visual acuity was 20/20 in both eyes. Ophthalmoscopy revealed an amelanotic, vascularized Ciliary Body Tumor with exudative retinal detachment and partial transillumination. On ultrasound examination the Tumor height was 8 mm and a low internal reflectivity was found. T2-weighted MRI scans showed a hypointense and T1-weighted scans a hyperintense intraocular mass with significant Gd-TPA enhancement. On the assumption that the diagnosis was consistent with an amelanotic Ciliary Body melanoma, a transscleral resection with adjuvant ruthenium-106 brachytherapy was performed. Visual acuity was 20/40 at 6 months after the operation. Results Routine stains revealed a pleomorphic Tumor composed mainly of spindle cells with palisading in some areas and a prominent intercellular fibrillary background. Immunohistochemistry showed positivity for desmin, vimentin and actin. No reactivity with S-100 and HMB-45 was seen. Intracytoplasmatic filaments and micropinocytotic vesicles were detected by transmission electron microscopy. These findings were consistent with the diagnosis of a Ciliary Body leiomyoma. Conclusion Typical clinical features of leiomyoma include a dome-shaped configuration and translucency, but the final diagnosis can only be confirmed by histology with the aid of immunohistochemistry and electron microscopy. Though rare, leiomyoma should be considered in the differential diagnosis of amelanotic uveal Tumors. Transscleral resection is the treatment of choice of anterior uveal leiomyomas, with a fairly good visual prognosis.
Jeffrey M Liebmann - One of the best experts on this subject based on the ideXlab platform.
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differential diagnosis of anterior segment cysts by ultrasound biomicroscopy
Ophthalmology, 1999Co-Authors: Paul T Finger, Flavio A Marigo, Koji Esaki, Hiroshi Ishikawa, David S Greenfield, Jeffrey M LiebmannAbstract:Abstract Background To describe the ultrasound biomicroscopic (UBM) features of anterior segment cysts. Design A retrospective case series. Participants One hundred eighteen eyes with anterior segment cysts examined by UBM at The New York Eye and Ear Infirmary between August 1992 and November 1997 were included in this study. Intervention The authors reviewed demographic and diagnostic data from the medical record including ocular and medical history, age, race, gender, and intraocular pressure. Ultrasound data concerning the type, number, position, and acoustic characteristics of cysts were recorded. The authors then correlated the written, clinical, and UBM characteristics. Results One hundred eyes (92.6%) had neuroepithelial cysts. Ninety (83.3%) of these had primary neuroepithelial cysts, 10 (9.3%) had cysts associated with uveitis, 7 (6.5%) had implantation cysts, and 1 (0.9%) had a cavitated Ciliary Body Tumor. Neuroepithelial cysts typically were round or ovoid, thin-walled, and echolucent. Of the 90 eyes with primary neuroepithelial cysts, 56 (62.2%) had 3 or fewer cysts; multiple cysts (>3 per eye) were found in 34 eyes (37.8%). The multiple cysts occupied more than 180° in 12 patients (13.3%). Primary neuroepithelial cysts were located at the iridoCiliary junction (74.2%), pars plicata (14.0%), pars plana (6.8%), and iris (5.0%). Implantation cysts (seven eyes) tended to have thicker walls and two contained a copious, echogenic material. Conclusion The UBM results provide important information regarding location and extent of anterior segment cystic lesions. Ultrasound characteristics may help differentiate between neuroepithelial, implantation, and neoplastic cysts.
Miriam N. Richter - One of the best experts on this subject based on the ideXlab platform.
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Transscleral resection of a Ciliary Body leiomyoma in a child: case report and review of the literature
Graefe's Archive for Clinical and Experimental Ophthalmology, 2003Co-Authors: Miriam N. Richter, Nikolaos E. Bechrakis, G. Stoltenburg-didinger, Michael H. FoersterAbstract:Purpose To present the case of a patient with leiomyoma of the Ciliary Body and discuss the histological features and treatment of this rare intraocular Tumor. Methods/case report A 13-year-old boy presented with an asymptomatic Tumor of the right eye. Visual acuity was 20/20 in both eyes. Ophthalmoscopy revealed an amelanotic, vascularized Ciliary Body Tumor with exudative retinal detachment and partial transillumination. On ultrasound examination the Tumor height was 8 mm and a low internal reflectivity was found. T2-weighted MRI scans showed a hypointense and T1-weighted scans a hyperintense intraocular mass with significant Gd-TPA enhancement. On the assumption that the diagnosis was consistent with an amelanotic Ciliary Body melanoma, a transscleral resection with adjuvant ruthenium-106 brachytherapy was performed. Visual acuity was 20/40 at 6 months after the operation. Results Routine stains revealed a pleomorphic Tumor composed mainly of spindle cells with palisading in some areas and a prominent intercellular fibrillary background. Immunohistochemistry showed positivity for desmin, vimentin and actin. No reactivity with S-100 and HMB-45 was seen. Intracytoplasmatic filaments and micropinocytotic vesicles were detected by transmission electron microscopy. These findings were consistent with the diagnosis of a Ciliary Body leiomyoma. Conclusion Typical clinical features of leiomyoma include a dome-shaped configuration and translucency, but the final diagnosis can only be confirmed by histology with the aid of immunohistochemistry and electron microscopy. Though rare, leiomyoma should be considered in the differential diagnosis of amelanotic uveal Tumors. Transscleral resection is the treatment of choice of anterior uveal leiomyomas, with a fairly good visual prognosis.
Lucas Vilarrodona - One of the best experts on this subject based on the ideXlab platform.
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Ciliary Body Tumor and cataract: local resection combined with phacoemulsification.
Journal of cataract and refractive surgery, 2001Co-Authors: Carlos Argento, Marı́a A Carrasco, Jorge Zárate, Martina L Zilli, Lucas VilarrodonaAbstract:A 57-year-old man developed a Ciliary Body mass, clinically diagnosed as malignant melanoma of the Ciliary Body, that produced a cataract in the right eye. Treatment was cataract surgery with sclerouvectomy performed simultaneously. Pathohistologic examination revealed an acquired adenoma of the nonpigmented Ciliary epithelium. The clinicopathologic features and treatment of this Tumor are discussed.
Flavio A Marigo - One of the best experts on this subject based on the ideXlab platform.
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differential diagnosis of anterior segment cysts by ultrasound biomicroscopy
Ophthalmology, 1999Co-Authors: Paul T Finger, Flavio A Marigo, Koji Esaki, Hiroshi Ishikawa, David S Greenfield, Jeffrey M LiebmannAbstract:Abstract Background To describe the ultrasound biomicroscopic (UBM) features of anterior segment cysts. Design A retrospective case series. Participants One hundred eighteen eyes with anterior segment cysts examined by UBM at The New York Eye and Ear Infirmary between August 1992 and November 1997 were included in this study. Intervention The authors reviewed demographic and diagnostic data from the medical record including ocular and medical history, age, race, gender, and intraocular pressure. Ultrasound data concerning the type, number, position, and acoustic characteristics of cysts were recorded. The authors then correlated the written, clinical, and UBM characteristics. Results One hundred eyes (92.6%) had neuroepithelial cysts. Ninety (83.3%) of these had primary neuroepithelial cysts, 10 (9.3%) had cysts associated with uveitis, 7 (6.5%) had implantation cysts, and 1 (0.9%) had a cavitated Ciliary Body Tumor. Neuroepithelial cysts typically were round or ovoid, thin-walled, and echolucent. Of the 90 eyes with primary neuroepithelial cysts, 56 (62.2%) had 3 or fewer cysts; multiple cysts (>3 per eye) were found in 34 eyes (37.8%). The multiple cysts occupied more than 180° in 12 patients (13.3%). Primary neuroepithelial cysts were located at the iridoCiliary junction (74.2%), pars plicata (14.0%), pars plana (6.8%), and iris (5.0%). Implantation cysts (seven eyes) tended to have thicker walls and two contained a copious, echogenic material. Conclusion The UBM results provide important information regarding location and extent of anterior segment cystic lesions. Ultrasound characteristics may help differentiate between neuroepithelial, implantation, and neoplastic cysts.