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Martin R. Prince - One of the best experts on this subject based on the ideXlab platform.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2015
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Martin R. Prince, Hong-lei Zhang
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P < 0.0001). The prevalence of Cisterna chyli enlargement more than the median (3.4 mm), was greater in ADPKD than in controls (99% versus 51%, P < 0.0001). On univariate analysis, Cisterna chyli diameter was inversely correlated with eGFR (r = −0.41; P < 0.0001) and directly correlated with TKV (r = 0.57; P < 0.0001), total renal cyst fraction (r = 0.61; P < 0.001), and liver volume (r = 0.17; P = 0.040). Multivariable linear regression modeling found a significant association of Cisterna chyli diameter with ADPKD diagnosis (B = 2.14; 95% confidence interval [CI]: 0.05–4.23; P = 0.04). Logistic regression analysis confirmed the association of ADPKD with an enlarged Cisterna chyli diameter (odds ratio = 68.4; 95%CI: 8.9–524, P < 0.0001). Conclusion Enlarged Cisterna chyli is highly prevalent in ADPKD patients but not in age and gender-matched controls. J. Magn. Reson. Imaging 2015;41:142–148. © 2014 Wiley Periodicals, Inc.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2014
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Hong-lei Zhang, Martin R. Prince
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P 

Jon D Blumenfeld - One of the best experts on this subject based on the ideXlab platform.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2015
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Martin R. Prince, Hong-lei Zhang
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P < 0.0001). The prevalence of Cisterna chyli enlargement more than the median (3.4 mm), was greater in ADPKD than in controls (99% versus 51%, P < 0.0001). On univariate analysis, Cisterna chyli diameter was inversely correlated with eGFR (r = −0.41; P < 0.0001) and directly correlated with TKV (r = 0.57; P < 0.0001), total renal cyst fraction (r = 0.61; P < 0.001), and liver volume (r = 0.17; P = 0.040). Multivariable linear regression modeling found a significant association of Cisterna chyli diameter with ADPKD diagnosis (B = 2.14; 95% confidence interval [CI]: 0.05–4.23; P = 0.04). Logistic regression analysis confirmed the association of ADPKD with an enlarged Cisterna chyli diameter (odds ratio = 68.4; 95%CI: 8.9–524, P < 0.0001). Conclusion Enlarged Cisterna chyli is highly prevalent in ADPKD patients but not in age and gender-matched controls. J. Magn. Reson. Imaging 2015;41:142–148. © 2014 Wiley Periodicals, Inc.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2014
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Hong-lei Zhang, Martin R. Prince
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P 

Nanda Deepa Thimmappa - One of the best experts on this subject based on the ideXlab platform.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2015
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Martin R. Prince, Hong-lei Zhang
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P < 0.0001). The prevalence of Cisterna chyli enlargement more than the median (3.4 mm), was greater in ADPKD than in controls (99% versus 51%, P < 0.0001). On univariate analysis, Cisterna chyli diameter was inversely correlated with eGFR (r = −0.41; P < 0.0001) and directly correlated with TKV (r = 0.57; P < 0.0001), total renal cyst fraction (r = 0.61; P < 0.001), and liver volume (r = 0.17; P = 0.040). Multivariable linear regression modeling found a significant association of Cisterna chyli diameter with ADPKD diagnosis (B = 2.14; 95% confidence interval [CI]: 0.05–4.23; P = 0.04). Logistic regression analysis confirmed the association of ADPKD with an enlarged Cisterna chyli diameter (odds ratio = 68.4; 95%CI: 8.9–524, P < 0.0001). Conclusion Enlarged Cisterna chyli is highly prevalent in ADPKD patients but not in age and gender-matched controls. J. Magn. Reson. Imaging 2015;41:142–148. © 2014 Wiley Periodicals, Inc.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2014
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Hong-lei Zhang, Martin R. Prince
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P 

Hong-lei Zhang - One of the best experts on this subject based on the ideXlab platform.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2015
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Martin R. Prince, Hong-lei Zhang
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P < 0.0001). The prevalence of Cisterna chyli enlargement more than the median (3.4 mm), was greater in ADPKD than in controls (99% versus 51%, P < 0.0001). On univariate analysis, Cisterna chyli diameter was inversely correlated with eGFR (r = −0.41; P < 0.0001) and directly correlated with TKV (r = 0.57; P < 0.0001), total renal cyst fraction (r = 0.61; P < 0.001), and liver volume (r = 0.17; P = 0.040). Multivariable linear regression modeling found a significant association of Cisterna chyli diameter with ADPKD diagnosis (B = 2.14; 95% confidence interval [CI]: 0.05–4.23; P = 0.04). Logistic regression analysis confirmed the association of ADPKD with an enlarged Cisterna chyli diameter (odds ratio = 68.4; 95%CI: 8.9–524, P < 0.0001). Conclusion Enlarged Cisterna chyli is highly prevalent in ADPKD patients but not in age and gender-matched controls. J. Magn. Reson. Imaging 2015;41:142–148. © 2014 Wiley Periodicals, Inc.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2014
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Hong-lei Zhang, Martin R. Prince
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P 

Michelle Ann C Cerilles - One of the best experts on this subject based on the ideXlab platform.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2015
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Martin R. Prince, Hong-lei Zhang
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P < 0.0001). The prevalence of Cisterna chyli enlargement more than the median (3.4 mm), was greater in ADPKD than in controls (99% versus 51%, P < 0.0001). On univariate analysis, Cisterna chyli diameter was inversely correlated with eGFR (r = −0.41; P < 0.0001) and directly correlated with TKV (r = 0.57; P < 0.0001), total renal cyst fraction (r = 0.61; P < 0.001), and liver volume (r = 0.17; P = 0.040). Multivariable linear regression modeling found a significant association of Cisterna chyli diameter with ADPKD diagnosis (B = 2.14; 95% confidence interval [CI]: 0.05–4.23; P = 0.04). Logistic regression analysis confirmed the association of ADPKD with an enlarged Cisterna chyli diameter (odds ratio = 68.4; 95%CI: 8.9–524, P < 0.0001). Conclusion Enlarged Cisterna chyli is highly prevalent in ADPKD patients but not in age and gender-matched controls. J. Magn. Reson. Imaging 2015;41:142–148. © 2014 Wiley Periodicals, Inc.

  • Cisterna chyli in autosomal dominant polycystic kidney disease
    Journal of Magnetic Resonance Imaging, 2014
    Co-Authors: Nanda Deepa Thimmappa, Jon D Blumenfeld, Michelle Ann C Cerilles, Allison Dunning, Stephanie Donahue, Warren O Bobb, Hong-lei Zhang, Martin R. Prince
    Abstract:

    Purpose After observing prominent Cisterna chyli in several patients with autosomal dominant polycystic kidney disease (ADPKD), we investigated the potential association of Cistern chyli enlargement with ADPKD. Materials and Methods Retrospective, cross-sectional analysis of abdominal and pelvic MRI at 1.5 Tesla (T) in 70 ADPKD patients (male 44.3%, 20–83 years, median = 53 years) were compared with 70 age and gender matched control subjects without ADPKD, cirrhosis, or cholestasis. Cisterna chyli diameter was measured on axial single shot fast spin echo (SSFSE) images at the level of T12–L2 and evaluated by multivariable regression models with covariates including estimated glomerular filtration rate (eGFR), total kidney volume (TKV), renal cyst fraction (cyst volume/kidney volume), and liver volume. Results Subjects with ADPKD had larger median Cisterna chyli diameter compared with those without ADPKD (6.1 mm versus 3.4 mm, P