The Experts below are selected from a list of 625608 Experts worldwide ranked by ideXlab platform
Daniel Hayoz - One of the best experts on this subject based on the ideXlab platform.
-
diagnosing pulmonary embolism in outpatients with Clinical Assessment d dimer measurement venous ultrasound and helical computed tomography a multicenter management study
The American Journal of Medicine, 2004Co-Authors: Arnaud Perrier, Pierremarie Roy, Drahomir Aujesky, Isabelle Chagnon, Nigel Howarth, Annelaurence Gourdier, Georges Leftheriotis, Ghassan Barghouth, Jacques Cornuz, Daniel HayozAbstract:Abstract Purpose To evaluate a diagnostic strategy for pulmonary embolism that combined Clinical Assessment, plasma D-dimer measurement, lower limb venous ultrasonography, and helical computed tomography (CT). Methods A cohort of 965 consecutive patients presenting to the emergency departments of three general and teaching hospitals with Clinically suspected pulmonary embolism underwent sequential noninvasive testing. Clinical probability was assessed by a prediction rule combined with implicit judgment. All patients were followed for 3 months. Results A normal D-dimer level ( Conclusion A noninvasive diagnostic strategy combining Clinical Assessment, D-dimer measurement, ultrasonography, and helical CT yielded a diagnosis in 99% of outpatients suspected of pulmonary embolism, and appeared to be safe, provided that CT was combined with ultrasonography to rule out the disease.
-
diagnosing pulmonary embolism in outpatients with Clinical Assessment d dimer measurement venous ultrasound and helical computed tomography a multicenter management study
The American Journal of Medicine, 2004Co-Authors: Arnaud Perrier, Drahomir Aujesky, Isabelle Chagnon, Nigel Howarth, Annelaurence Gourdier, Georges Leftheriotis, Ghassan Barghouth, Jacques Cornuz, Daniel Hayoz, Henri BounameauxAbstract:PURPOSE: To evaluate a diagnostic strategy for pulmonary embolism that combined Clinical Assessment, plasma D-dimer measurement, lower limb venous ultrasonography, and helical computed tomography (CT). METHODS: A cohort of 965 consecutive patients presenting to the emergency departments of three general and teaching hospitals with Clinically suspected pulmonary embolism underwent sequential noninvasive testing. Clinical probability was assessed by a prediction rule combined with implicit judgment. All patients were followed for 3 months. RESULTS: A normal D-dimer level (<500 microg/L by a rapid enzyme-linked immunosorbent assay) ruled out venous thromboembolism in 280 patients (29%), and finding a deep vein thrombosis by ultrasonography established the diagnosis in 92 patients (9.5%). Helical CT was required in only 593 patients (61%) and showed pulmonary embolism in 124 patients (12.8%). Pulmonary embolism was considered ruled out in the 450 patients (46.6%) with a negative ultrasound and CT scan and a low-to-intermediate Clinical probability. The 8 patients with a negative ultrasound and CT scan despite a high Clinical probability proceeded to pulmonary angiography (positive: 2; negative: 6). Helical CT was inconclusive in 11 patients (pulmonary embolism: 4; no pulmonary embolism: 7). The overall prevalence of pulmonary embolism was 23%. Patients classified as not having pulmonary embolism were not anticoagulated during follow-up and had a 3-month thromboembolic risk of 1.0% (95% confidence interval: 0.5% to 2.1%). CONCLUSION: A noninvasive diagnostic strategy combining Clinical Assessment, D-dimer measurement, ultrasonography, and helical CT yielded a diagnosis in 99% of outpatients suspected of pulmonary embolism, and appeared to be safe, provided that CT was combined with ultrasonography to rule out the disease.
Arnaud Perrier - One of the best experts on this subject based on the ideXlab platform.
-
diagnosing pulmonary embolism in outpatients with Clinical Assessment d dimer measurement venous ultrasound and helical computed tomography a multicenter management study
The American Journal of Medicine, 2004Co-Authors: Arnaud Perrier, Pierremarie Roy, Drahomir Aujesky, Isabelle Chagnon, Nigel Howarth, Annelaurence Gourdier, Georges Leftheriotis, Ghassan Barghouth, Jacques Cornuz, Daniel HayozAbstract:Abstract Purpose To evaluate a diagnostic strategy for pulmonary embolism that combined Clinical Assessment, plasma D-dimer measurement, lower limb venous ultrasonography, and helical computed tomography (CT). Methods A cohort of 965 consecutive patients presenting to the emergency departments of three general and teaching hospitals with Clinically suspected pulmonary embolism underwent sequential noninvasive testing. Clinical probability was assessed by a prediction rule combined with implicit judgment. All patients were followed for 3 months. Results A normal D-dimer level ( Conclusion A noninvasive diagnostic strategy combining Clinical Assessment, D-dimer measurement, ultrasonography, and helical CT yielded a diagnosis in 99% of outpatients suspected of pulmonary embolism, and appeared to be safe, provided that CT was combined with ultrasonography to rule out the disease.
-
diagnosing pulmonary embolism in outpatients with Clinical Assessment d dimer measurement venous ultrasound and helical computed tomography a multicenter management study
The American Journal of Medicine, 2004Co-Authors: Arnaud Perrier, Drahomir Aujesky, Isabelle Chagnon, Nigel Howarth, Annelaurence Gourdier, Georges Leftheriotis, Ghassan Barghouth, Jacques Cornuz, Daniel Hayoz, Henri BounameauxAbstract:PURPOSE: To evaluate a diagnostic strategy for pulmonary embolism that combined Clinical Assessment, plasma D-dimer measurement, lower limb venous ultrasonography, and helical computed tomography (CT). METHODS: A cohort of 965 consecutive patients presenting to the emergency departments of three general and teaching hospitals with Clinically suspected pulmonary embolism underwent sequential noninvasive testing. Clinical probability was assessed by a prediction rule combined with implicit judgment. All patients were followed for 3 months. RESULTS: A normal D-dimer level (<500 microg/L by a rapid enzyme-linked immunosorbent assay) ruled out venous thromboembolism in 280 patients (29%), and finding a deep vein thrombosis by ultrasonography established the diagnosis in 92 patients (9.5%). Helical CT was required in only 593 patients (61%) and showed pulmonary embolism in 124 patients (12.8%). Pulmonary embolism was considered ruled out in the 450 patients (46.6%) with a negative ultrasound and CT scan and a low-to-intermediate Clinical probability. The 8 patients with a negative ultrasound and CT scan despite a high Clinical probability proceeded to pulmonary angiography (positive: 2; negative: 6). Helical CT was inconclusive in 11 patients (pulmonary embolism: 4; no pulmonary embolism: 7). The overall prevalence of pulmonary embolism was 23%. Patients classified as not having pulmonary embolism were not anticoagulated during follow-up and had a 3-month thromboembolic risk of 1.0% (95% confidence interval: 0.5% to 2.1%). CONCLUSION: A noninvasive diagnostic strategy combining Clinical Assessment, D-dimer measurement, ultrasonography, and helical CT yielded a diagnosis in 99% of outpatients suspected of pulmonary embolism, and appeared to be safe, provided that CT was combined with ultrasonography to rule out the disease.
Yu Miao - One of the best experts on this subject based on the ideXlab platform.
-
diagnostic values of 3 methods for evaluating meniscal healing status after meniscal repair comparison among second look arthroscopy Clinical Assessment and magnetic resonance imaging
American Journal of Sports Medicine, 2011Co-Authors: Yu Miao, Xi Gong, Zhuozhao Zheng, Kevin Kar Ming LeungAbstract:Background: The main diagnostic methods for evaluating repaired menisci include second-look arthroscopy, Clinical Assessment, and magnetic resonance imaging (MRI). None of the previous studies applied all 3 methods for each consecutive case nor made any systematic comparison among them.Purpose: This study was undertaken to compare the diagnostic values of the 3 different methods in an attempt to propose suggestions for evaluating meniscal healing results.Study Design: Cohort study (diagnosis); Level of evidence, 2.Methods: Eighty-one patients (89 menisci), with a mean age of 25.4 years (standard deviation [SD], 7.7; range, 15-50 years), underwent arthroscopic meniscal repair, including 65 medial menisci and 24 lateral menisci. Follow-up evaluation for each meniscus included Clinical Assessment, second-look arthroscopy, and postoperative MRI, with a mean follow-up time of 25.4 months (SD, 6.0; range, 17.4-48.3 months). Defined criteria for unhealed meniscus were any symptoms such as joint-line tenderness, ...
-
Diagnostic Values of 3 Methods for Evaluating Meniscal Healing Status After Meniscal Repair Comparison Among Second-Look Arthroscopy, Clinical Assessment, and Magnetic Resonance Imaging
american journal of sports medicine, 2011Co-Authors: Yu Miao, Ao Ying-fang, Yu Jia-kuo, Zheng Zhuo-zhao, Xi Gong, Leung, Kevin Kar MingAbstract:Background: The main diagnostic methods for evaluating repaired menisci include second-look arthroscopy, Clinical Assessment, and magnetic resonance imaging (MRI). None of the previous studies applied all 3 methods for each consecutive case nor made any systematic comparison among them. Purpose: This study was undertaken to compare the diagnostic values of the 3 different methods in an attempt to propose suggestions for evaluating meniscal healing results. Study Design: Cohort study (diagnosis); Level of evidence, 2. Methods: Eighty-one patients (89 menisci), with a mean age of 25.4 years (standard deviation [SD], 7.7; range, 15-50 years), underwent arthroscopic meniscal repair, including 65 medial menisci and 24 lateral menisci. Follow-up evaluation for each meniscus included Clinical Assessment, second-look arthroscopy, and postoperative MRI, with a mean follow-up time of 25.4 months (SD, 6.0; range, 17.4-48.3 months). Defined criteria for unhealed meniscus were any symptoms such as joint-line tenderness, swelling, locking, or positive McMurray test for Clinical Assessment; cleft or instability on second-look arthroscopy; and grade 3 signal intensity shown at the repaired site on postoperative MRI. Results: Seventy-seven menisci were confirmed completely healed by second-look arthroscopy, with a total healing rate of 86.5%. Clinical Assessment found 63 menisci healed, with a Clinical healing rate of 70.8% (sensitivity, 58.3%; specificity, 75.3%; accuracy, 73.0%). By using the second-look arthroscopy as the standard, the sensitivity, specificity, and accuracy, respectively, were calculated for MRI in 5 sequences: sagittal T1: 91.7%, 58.4%, 62.9%; sagittal proton density (PD): 83.3%, 40.3%, 46.1%; sagittal T2: 58.3%, 89.6%, 85.4%; coronal PD: 75.0%, 74.0%, 74.2%; and coronal T2: 41.7%, 98.7%, 91.0%. Conclusion: Second-look arthroscopy was the most dependable way to determine meniscal healing. Clinical Assessment had obvious limitations in diagnosing healed menisci. On MRI examination, T2-weighted sequences had obviously higher specificity and accuracy, while PD and T1 had higher sensitivity. The diagnostic value could be improved by a combined application of different sequences.OrthopedicsSport SciencesSCI(E)PubMed17ARTICLE4735-7423
Henri Bounameaux - One of the best experts on this subject based on the ideXlab platform.
-
diagnosing pulmonary embolism in outpatients with Clinical Assessment d dimer measurement venous ultrasound and helical computed tomography a multicenter management study
The American Journal of Medicine, 2004Co-Authors: Arnaud Perrier, Drahomir Aujesky, Isabelle Chagnon, Nigel Howarth, Annelaurence Gourdier, Georges Leftheriotis, Ghassan Barghouth, Jacques Cornuz, Daniel Hayoz, Henri BounameauxAbstract:PURPOSE: To evaluate a diagnostic strategy for pulmonary embolism that combined Clinical Assessment, plasma D-dimer measurement, lower limb venous ultrasonography, and helical computed tomography (CT). METHODS: A cohort of 965 consecutive patients presenting to the emergency departments of three general and teaching hospitals with Clinically suspected pulmonary embolism underwent sequential noninvasive testing. Clinical probability was assessed by a prediction rule combined with implicit judgment. All patients were followed for 3 months. RESULTS: A normal D-dimer level (<500 microg/L by a rapid enzyme-linked immunosorbent assay) ruled out venous thromboembolism in 280 patients (29%), and finding a deep vein thrombosis by ultrasonography established the diagnosis in 92 patients (9.5%). Helical CT was required in only 593 patients (61%) and showed pulmonary embolism in 124 patients (12.8%). Pulmonary embolism was considered ruled out in the 450 patients (46.6%) with a negative ultrasound and CT scan and a low-to-intermediate Clinical probability. The 8 patients with a negative ultrasound and CT scan despite a high Clinical probability proceeded to pulmonary angiography (positive: 2; negative: 6). Helical CT was inconclusive in 11 patients (pulmonary embolism: 4; no pulmonary embolism: 7). The overall prevalence of pulmonary embolism was 23%. Patients classified as not having pulmonary embolism were not anticoagulated during follow-up and had a 3-month thromboembolic risk of 1.0% (95% confidence interval: 0.5% to 2.1%). CONCLUSION: A noninvasive diagnostic strategy combining Clinical Assessment, D-dimer measurement, ultrasonography, and helical CT yielded a diagnosis in 99% of outpatients suspected of pulmonary embolism, and appeared to be safe, provided that CT was combined with ultrasonography to rule out the disease.
Georges Leftheriotis - One of the best experts on this subject based on the ideXlab platform.
-
diagnosing pulmonary embolism in outpatients with Clinical Assessment d dimer measurement venous ultrasound and helical computed tomography a multicenter management study
The American Journal of Medicine, 2004Co-Authors: Arnaud Perrier, Pierremarie Roy, Drahomir Aujesky, Isabelle Chagnon, Nigel Howarth, Annelaurence Gourdier, Georges Leftheriotis, Ghassan Barghouth, Jacques Cornuz, Daniel HayozAbstract:Abstract Purpose To evaluate a diagnostic strategy for pulmonary embolism that combined Clinical Assessment, plasma D-dimer measurement, lower limb venous ultrasonography, and helical computed tomography (CT). Methods A cohort of 965 consecutive patients presenting to the emergency departments of three general and teaching hospitals with Clinically suspected pulmonary embolism underwent sequential noninvasive testing. Clinical probability was assessed by a prediction rule combined with implicit judgment. All patients were followed for 3 months. Results A normal D-dimer level ( Conclusion A noninvasive diagnostic strategy combining Clinical Assessment, D-dimer measurement, ultrasonography, and helical CT yielded a diagnosis in 99% of outpatients suspected of pulmonary embolism, and appeared to be safe, provided that CT was combined with ultrasonography to rule out the disease.
-
diagnosing pulmonary embolism in outpatients with Clinical Assessment d dimer measurement venous ultrasound and helical computed tomography a multicenter management study
The American Journal of Medicine, 2004Co-Authors: Arnaud Perrier, Drahomir Aujesky, Isabelle Chagnon, Nigel Howarth, Annelaurence Gourdier, Georges Leftheriotis, Ghassan Barghouth, Jacques Cornuz, Daniel Hayoz, Henri BounameauxAbstract:PURPOSE: To evaluate a diagnostic strategy for pulmonary embolism that combined Clinical Assessment, plasma D-dimer measurement, lower limb venous ultrasonography, and helical computed tomography (CT). METHODS: A cohort of 965 consecutive patients presenting to the emergency departments of three general and teaching hospitals with Clinically suspected pulmonary embolism underwent sequential noninvasive testing. Clinical probability was assessed by a prediction rule combined with implicit judgment. All patients were followed for 3 months. RESULTS: A normal D-dimer level (<500 microg/L by a rapid enzyme-linked immunosorbent assay) ruled out venous thromboembolism in 280 patients (29%), and finding a deep vein thrombosis by ultrasonography established the diagnosis in 92 patients (9.5%). Helical CT was required in only 593 patients (61%) and showed pulmonary embolism in 124 patients (12.8%). Pulmonary embolism was considered ruled out in the 450 patients (46.6%) with a negative ultrasound and CT scan and a low-to-intermediate Clinical probability. The 8 patients with a negative ultrasound and CT scan despite a high Clinical probability proceeded to pulmonary angiography (positive: 2; negative: 6). Helical CT was inconclusive in 11 patients (pulmonary embolism: 4; no pulmonary embolism: 7). The overall prevalence of pulmonary embolism was 23%. Patients classified as not having pulmonary embolism were not anticoagulated during follow-up and had a 3-month thromboembolic risk of 1.0% (95% confidence interval: 0.5% to 2.1%). CONCLUSION: A noninvasive diagnostic strategy combining Clinical Assessment, D-dimer measurement, ultrasonography, and helical CT yielded a diagnosis in 99% of outpatients suspected of pulmonary embolism, and appeared to be safe, provided that CT was combined with ultrasonography to rule out the disease.