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Alexandre R Zlotta - One of the best experts on this subject based on the ideXlab platform.

  • possible mechanisms of action of transurethral needle ablation of the prostate on benign prostatic hyperplasia symptoms a neurohistochemical study
    The Journal of Urology, 1997
    Co-Authors: Alexandre R Zlotta, Marieodile Peny, Gil Raviv, J Haot, Jean-christophe Noel, Claude Schulman
    Abstract:

    ABSTRACTPurpose: Transurethral needle ablation of benign prostatic hypertrophy (BPH) is a rapid, anesthesia-free outpatient procedure using low level radiofrequency energy that produces Coagulative Necrosis lesions at temperatures of approximately 100C. Clinically, significant improvement in objective and subjective parameters has been observed in BPH patients. Transurethral needle ablation has also been shown to be effective in relieving urinary retention. However, the precise mechanism of action of this procedure remains to be clarified. Ablation could produce its action on the dynamic component of the infravesical outlet obstruction. We analyzed the possible effects of transurethral needle ablation on the intraprostatic innervation.Materials and Methods: Histological sections from 10 open prostatectomy specimens (BPH) recovered 1 to 46 days after transurethral needle ablation were stained with hematoxylin and eosin and an immunohistochemical technique, using antibodies against S100 proteins and nonspec...

  • transurethral needle ablation of the prostate a new treatment of benign prostatic hyperplasia using interstitial low level radiofrequency energy
    Current Opinion in Urology, 1995
    Co-Authors: Claude Schulman, Alexandre R Zlotta
    Abstract:

    Transurethral needle ablation is a new method of treating benign prostatic hyperplasia. Needles on a urethral catheter deliver low-level radiofrequency power directly to a localized area of the prostate. Extensive Coagulative Necrosis is produced by central lesion temperatures above 100°C. The needles have adjustable shields to protect the urethra if necessary. The instrument is positioned by direct vision using fibre optics. Clinical and pathological studies of transurethral needle ablation have shown the following: (1) that it is feasible and safe; (2) that it can create localized controlled necrotic lesions, as demonstrated by histopathological studies of operative specimen and magnetic resonance imaging; (3) an excellent tolerance of the procedure as an anaesthesia-free outpatient treatment; and (4) an excellent improvement in objective and subjective parameters, such as peak flow rate and International Prostate Symptom Score, after 6 months. Transurethral needle ablation is a promising, anaesthesia-free, alternative treatment for men with symptomatic benign prostatic hyperplasia, but long-term outcome will require further evaluation over several years.

Claude Schulman - One of the best experts on this subject based on the ideXlab platform.

  • possible mechanisms of action of transurethral needle ablation of the prostate on benign prostatic hyperplasia symptoms a neurohistochemical study
    The Journal of Urology, 1997
    Co-Authors: Alexandre R Zlotta, Marieodile Peny, Gil Raviv, J Haot, Jean-christophe Noel, Claude Schulman
    Abstract:

    ABSTRACTPurpose: Transurethral needle ablation of benign prostatic hypertrophy (BPH) is a rapid, anesthesia-free outpatient procedure using low level radiofrequency energy that produces Coagulative Necrosis lesions at temperatures of approximately 100C. Clinically, significant improvement in objective and subjective parameters has been observed in BPH patients. Transurethral needle ablation has also been shown to be effective in relieving urinary retention. However, the precise mechanism of action of this procedure remains to be clarified. Ablation could produce its action on the dynamic component of the infravesical outlet obstruction. We analyzed the possible effects of transurethral needle ablation on the intraprostatic innervation.Materials and Methods: Histological sections from 10 open prostatectomy specimens (BPH) recovered 1 to 46 days after transurethral needle ablation were stained with hematoxylin and eosin and an immunohistochemical technique, using antibodies against S100 proteins and nonspec...

  • transurethral needle ablation of the prostate a new treatment of benign prostatic hyperplasia using interstitial low level radiofrequency energy
    Current Opinion in Urology, 1995
    Co-Authors: Claude Schulman, Alexandre R Zlotta
    Abstract:

    Transurethral needle ablation is a new method of treating benign prostatic hyperplasia. Needles on a urethral catheter deliver low-level radiofrequency power directly to a localized area of the prostate. Extensive Coagulative Necrosis is produced by central lesion temperatures above 100°C. The needles have adjustable shields to protect the urethra if necessary. The instrument is positioned by direct vision using fibre optics. Clinical and pathological studies of transurethral needle ablation have shown the following: (1) that it is feasible and safe; (2) that it can create localized controlled necrotic lesions, as demonstrated by histopathological studies of operative specimen and magnetic resonance imaging; (3) an excellent tolerance of the procedure as an anaesthesia-free outpatient treatment; and (4) an excellent improvement in objective and subjective parameters, such as peak flow rate and International Prostate Symptom Score, after 6 months. Transurethral needle ablation is a promising, anaesthesia-free, alternative treatment for men with symptomatic benign prostatic hyperplasia, but long-term outcome will require further evaluation over several years.

Elias Campo - One of the best experts on this subject based on the ideXlab platform.

  • enigmatic kikuchi fujimoto disease a comprehensive review
    American Journal of Clinical Pathology, 2004
    Co-Authors: X Bosch, Antonio Guilabert, Rosa Miquel, Elias Campo
    Abstract:

    To determine the clinicopathologic significance of Kikuchi-Fujimoto disease (KFD) and review the literature on this condition, we conducted a MEDLINE search of English-language articles published between 1972 and December 2003. KFD has a worldwide distribution, and Asiatic people have a higher prevalence. Its pathogenesis remains controversial. Patients are young and seek care because of acute tender, cervical lymphadenopathy and low-grade fever. Histologic findings include paracortical areas of Coagulative Necrosis with abundant karyorrhectic debris. Karyorrhectic foci consist of various types of histiocytes, plasmacytoid monocytes, immunoblasts, and small and large lymphocytes. There is an abundance of T cells with predominance of CD8+ over CD4+ T cells. Differential diagnosis includes lymphoma, lymphadenitis associated with systemic lupus erythematosus, and even adenocarcinoma. KFD is an uncommon, self-limited, and perhaps underdiagnosed process with an excellent prognosis. Accurate clinicopathologic recognition is crucial, particularly because KFD can be mistaken for malignant lymphoma.

  • enigmatic kikuchi fujimoto disease
    American Journal of Clinical Pathology, 2004
    Co-Authors: X Bosch, Antonio Guilabert, Rosa Miquel, Elias Campo
    Abstract:

    To determine the clinicopathologic significance of Kikuchi-Fujimoto disease (KFD) and review the literature on this condition, we conducted a MEDLINE search of English-language articles published between 1972 and December 2003. KFD has a worldwide distribution, and Asiatic people have a higher prevalence. Its pathogenesis remains controversial. Patients are young and seek care because of acute tender, cervical lymphadenopathy and low-grade fever. Histologic findings include paracortical areas of Coagulative Necrosis with abundant karyorrhectic debris. Karyorrhectic foci consist of various types of histiocytes, plasmacytoid monocytes, immunoblasts, and small and large lymphocytes. There is an abundance of T cells with predominance of CD8+ over CD4+ T cells. Differential diagnosis includes lymphoma, lymphadenitis associated with systemic lupus erythematosus, and even adenocarcinoma. KFD is an uncommon, self-limited, and perhaps underdiagnosed process with an excellent prognosis. Accurate clinicopathologic recognition is crucial, particularly because KFD can be mistaken for malignant lymphoma.

X Bosch - One of the best experts on this subject based on the ideXlab platform.

  • enigmatic kikuchi fujimoto disease a comprehensive review
    American Journal of Clinical Pathology, 2004
    Co-Authors: X Bosch, Antonio Guilabert, Rosa Miquel, Elias Campo
    Abstract:

    To determine the clinicopathologic significance of Kikuchi-Fujimoto disease (KFD) and review the literature on this condition, we conducted a MEDLINE search of English-language articles published between 1972 and December 2003. KFD has a worldwide distribution, and Asiatic people have a higher prevalence. Its pathogenesis remains controversial. Patients are young and seek care because of acute tender, cervical lymphadenopathy and low-grade fever. Histologic findings include paracortical areas of Coagulative Necrosis with abundant karyorrhectic debris. Karyorrhectic foci consist of various types of histiocytes, plasmacytoid monocytes, immunoblasts, and small and large lymphocytes. There is an abundance of T cells with predominance of CD8+ over CD4+ T cells. Differential diagnosis includes lymphoma, lymphadenitis associated with systemic lupus erythematosus, and even adenocarcinoma. KFD is an uncommon, self-limited, and perhaps underdiagnosed process with an excellent prognosis. Accurate clinicopathologic recognition is crucial, particularly because KFD can be mistaken for malignant lymphoma.

  • enigmatic kikuchi fujimoto disease
    American Journal of Clinical Pathology, 2004
    Co-Authors: X Bosch, Antonio Guilabert, Rosa Miquel, Elias Campo
    Abstract:

    To determine the clinicopathologic significance of Kikuchi-Fujimoto disease (KFD) and review the literature on this condition, we conducted a MEDLINE search of English-language articles published between 1972 and December 2003. KFD has a worldwide distribution, and Asiatic people have a higher prevalence. Its pathogenesis remains controversial. Patients are young and seek care because of acute tender, cervical lymphadenopathy and low-grade fever. Histologic findings include paracortical areas of Coagulative Necrosis with abundant karyorrhectic debris. Karyorrhectic foci consist of various types of histiocytes, plasmacytoid monocytes, immunoblasts, and small and large lymphocytes. There is an abundance of T cells with predominance of CD8+ over CD4+ T cells. Differential diagnosis includes lymphoma, lymphadenitis associated with systemic lupus erythematosus, and even adenocarcinoma. KFD is an uncommon, self-limited, and perhaps underdiagnosed process with an excellent prognosis. Accurate clinicopathologic recognition is crucial, particularly because KFD can be mistaken for malignant lymphoma.

Stephen B Solomon - One of the best experts on this subject based on the ideXlab platform.

  • high intensity focused ultrasound ablation of the vas deferens in a canine model
    The Journal of Urology, 2002
    Co-Authors: William W Roberts, David Y Chan, Nathaniel M Fried, James E Wright, Theresa L Nicol, Thomas W Jarrett, Louis R Kavoussi, Stephen B Solomon
    Abstract:

    Purpose: High intensity focused ultrasound is an ablative technology capable of producing thermal Coagulative Necrosis of sub-surface structures without injuring intervening tissues. We assessed the feasibility of using high intensity focused ultrasound to produce occlusion of the canine vas deferens.Materials and Methods: A high intensity focused ultrasound transducer was incorporated into a hand held clip specially designed to grasp the vas deferens transcutaneously. Slots within the jaws of the clip ensured that the vas deferens and high intensity focused ultrasound target zone were properly co-located. We ablated 10 vasa using a range of power and time parameters. At 2 weeks after ablation each vas, epididymis and testis was surgically harvested en bloc. Retrograde vasography was performed to assess vasal occlusion, followed by pathological analysis.Results: High intensity focused ultrasound occlusion of the vas deferens was confirmed in 4 specimens ablated with parameters at the upper end of the para...