The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

Shigeo Hirose - One of the best experts on this subject based on the ideXlab platform.

  • a passive weight Compensation Mechanism with a non circular pulley and a spring
    International Conference on Robotics and Automation, 2010
    Co-Authors: Gen Endo, Hiroya Yamada, Akira Yajima, Masaru Ogata, Shigeo Hirose
    Abstract:

    We propose a new weight Compensation Mechanism with a non-circular pulley and a spring. We show the basic principle and numerical design method to derive the shape of the non-circular pulley. After demonstration of the weight Compensation for an inverted/ordinary pendulum system, we extend the same Mechanism to a parallel five-bar linkage system, analyzing the required torques using transposed Jacobian matrices. Finally, we develop a three degree of freedom manipulator with relatively small output actuators and verified that the weight Compensation Mechanism significantly contributes to decrease static torques to keep the same posture within manipulator's work space.

  • a weight Compensation Mechanism with a non circular pulley and a spring application to a parallel four bar linkage arm
    SICE journal of control measurement and system integration, 2010
    Co-Authors: Gen Endo, Hiroya Yamada, Akira Yajima, Masaru Ogata, Shigeo Hirose
    Abstract:

    We propose a new weight Compensation Mechanism with a non-circular pulley and a spring. We show the basic principle and numerical design method to derive the shape of the non-circular pulley. After demonstration of the weight Compensation for an inverted/ordinary pendulum system, we extend the same Mechanism to a parallel four-bar linkage system, analyzing the required torques with transposed Jacobian matrices. Finally, we develop a 3 D.O.F manipulator with relatively small output actuators and verify that the weight Compensation Mechanism greatly contributes to decrease static torques to keep the same posture within manipulator's work space.

  • a weight Compensation Mechanism with a non circular pulley and a spring application to a parallel four bar linkage arm
    SICE journal of control measurement and system integration, 2010
    Co-Authors: Gen Endo, Hiroya Yamada, Akira Yajima, Masaru Ogata, Shigeo Hirose
    Abstract:

    We propose a new weight Compensation Mechanism with a non-circular pulley and a spring. We show the basic principle and a numerical design method to derive the shape of the non-circular pulley. Aft...

  • float arm v hyper redundant manipulator with wire driven weight Compensation Mechanism
    International Conference on Robotics and Automation, 2003
    Co-Authors: Shigeo Hirose, T Ishii, A Haishi
    Abstract:

    In this paper, the wire-driven weight-Compensation Mechanism is proposed. This Mechanism consists of a parallelogram linkage Mechanism that has an extended portion with the wired double pulley. This is a lighter solution compared to others since no springs are utilized. Below, a detailed description of this new weight-Compensation Mechanism and performances of Float Arm V with this new Mechanism are given.

Michael G Poirier - One of the best experts on this subject based on the ideXlab platform.

  • dissociation rate Compensation Mechanism for budding yeast pioneer transcription factors
    eLife, 2019
    Co-Authors: Benjamin T Donovan, Hengye Chen, Caroline Jipa, Lu Bai, Michael G Poirier
    Abstract:

    Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement. To understand this process mechanistically, we investigated two Saccharomyces cerevisiae TFs, Reb1 and Cbf1. We show that these factors bind to their sites within nucleosomes with similar binding affinities as to naked DNA, trapping a partially unwrapped nucleosome without histone eviction. Both the binding and dissociation rates of Reb1 and Cbf1 are significantly slower at the nucleosomal sites relative to those for naked DNA, demonstrating that the high affinities are achieved by increasing the dwell time on nucleosomes in order to compensate for reduced binding. Reb1 also shows slow migration rate in the yeast nuclei. These properties are similar to those of human pioneer factors (PFs), suggesting that the Mechanism of nucleosome targeting is conserved from yeast to humans.

  • dissociation rate Compensation Mechanism for budding yeast pioneer transcription factors
    bioRxiv, 2018
    Co-Authors: Benjamin T Donovan, Hengye Chen, Caroline Jipa, Lu Bai, Michael G Poirier
    Abstract:

    Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement. To mechanistically understand this process, we investigated two S. cerevisiae TFs , Reb1 and Cbf1. We show these factors bind their sites within nucleosomes with similar affinities to naked DNA, trapping a partially unwrapped nucleosome without histone eviction. Both the binding and dissociation rates of Reb1 and Cbf1 are significantly slower at the nucleosomal sites relative to DNA, demonstrating that the high affinities are achieved by increasing the dwell time on nucleosomes to compensate for reduced binding. Reb1 also shows slow migration rate in the yeast nuclei. These properties are similar to human pioneer factors (PFs), suggesting the Mechanism of nucleosome targeting is conserved from yeast to human.

Gen Endo - One of the best experts on this subject based on the ideXlab platform.

  • a passive weight Compensation Mechanism with a non circular pulley and a spring
    International Conference on Robotics and Automation, 2010
    Co-Authors: Gen Endo, Hiroya Yamada, Akira Yajima, Masaru Ogata, Shigeo Hirose
    Abstract:

    We propose a new weight Compensation Mechanism with a non-circular pulley and a spring. We show the basic principle and numerical design method to derive the shape of the non-circular pulley. After demonstration of the weight Compensation for an inverted/ordinary pendulum system, we extend the same Mechanism to a parallel five-bar linkage system, analyzing the required torques using transposed Jacobian matrices. Finally, we develop a three degree of freedom manipulator with relatively small output actuators and verified that the weight Compensation Mechanism significantly contributes to decrease static torques to keep the same posture within manipulator's work space.

  • a weight Compensation Mechanism with a non circular pulley and a spring application to a parallel four bar linkage arm
    SICE journal of control measurement and system integration, 2010
    Co-Authors: Gen Endo, Hiroya Yamada, Akira Yajima, Masaru Ogata, Shigeo Hirose
    Abstract:

    We propose a new weight Compensation Mechanism with a non-circular pulley and a spring. We show the basic principle and numerical design method to derive the shape of the non-circular pulley. After demonstration of the weight Compensation for an inverted/ordinary pendulum system, we extend the same Mechanism to a parallel four-bar linkage system, analyzing the required torques with transposed Jacobian matrices. Finally, we develop a 3 D.O.F manipulator with relatively small output actuators and verify that the weight Compensation Mechanism greatly contributes to decrease static torques to keep the same posture within manipulator's work space.

  • a weight Compensation Mechanism with a non circular pulley and a spring application to a parallel four bar linkage arm
    SICE journal of control measurement and system integration, 2010
    Co-Authors: Gen Endo, Hiroya Yamada, Akira Yajima, Masaru Ogata, Shigeo Hirose
    Abstract:

    We propose a new weight Compensation Mechanism with a non-circular pulley and a spring. We show the basic principle and a numerical design method to derive the shape of the non-circular pulley. Aft...

Benjamin T Donovan - One of the best experts on this subject based on the ideXlab platform.

  • dissociation rate Compensation Mechanism for budding yeast pioneer transcription factors
    eLife, 2019
    Co-Authors: Benjamin T Donovan, Hengye Chen, Caroline Jipa, Lu Bai, Michael G Poirier
    Abstract:

    Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement. To understand this process mechanistically, we investigated two Saccharomyces cerevisiae TFs, Reb1 and Cbf1. We show that these factors bind to their sites within nucleosomes with similar binding affinities as to naked DNA, trapping a partially unwrapped nucleosome without histone eviction. Both the binding and dissociation rates of Reb1 and Cbf1 are significantly slower at the nucleosomal sites relative to those for naked DNA, demonstrating that the high affinities are achieved by increasing the dwell time on nucleosomes in order to compensate for reduced binding. Reb1 also shows slow migration rate in the yeast nuclei. These properties are similar to those of human pioneer factors (PFs), suggesting that the Mechanism of nucleosome targeting is conserved from yeast to humans.

  • dissociation rate Compensation Mechanism for budding yeast pioneer transcription factors
    bioRxiv, 2018
    Co-Authors: Benjamin T Donovan, Hengye Chen, Caroline Jipa, Lu Bai, Michael G Poirier
    Abstract:

    Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement. To mechanistically understand this process, we investigated two S. cerevisiae TFs , Reb1 and Cbf1. We show these factors bind their sites within nucleosomes with similar affinities to naked DNA, trapping a partially unwrapped nucleosome without histone eviction. Both the binding and dissociation rates of Reb1 and Cbf1 are significantly slower at the nucleosomal sites relative to DNA, demonstrating that the high affinities are achieved by increasing the dwell time on nucleosomes to compensate for reduced binding. Reb1 also shows slow migration rate in the yeast nuclei. These properties are similar to human pioneer factors (PFs), suggesting the Mechanism of nucleosome targeting is conserved from yeast to human.

Ralf Lucklum - One of the best experts on this subject based on the ideXlab platform.

  • differential phononic crystal sensor towards a temperature Compensation Mechanism for field applications development
    Sensors, 2017
    Co-Authors: Simon Villaarango, David Betancur Sanchez, Robinson Torres, P A Kyriacou, Ralf Lucklum
    Abstract:

    Phononic crystals are resonant structures with great potential to be implemented in applications as liquid sensors. The use of the symmetry reduction technique allows introducing relevant transmission features inside bandgaps by creating defect modes in a periodic regular structure. These features can be used as measures to quantify changes in the speed of sound of liquid samples that could be related to the concentration of analytes or the presence of pathogens among other interesting applications. In order to be able to implement this new technology in more challenging applications, such as biomedical applications, it is necessary to have a very precise and accurate measurement. Changes in temperature greatly affect the speed of sound of the liquid samples, causing errors in the measurements. This article presents a phononic crystal sensor that, by introducing additional defect modes, can carry out differential measurements as a temperature Compensation Mechanism. Theoretical studies using the transmission line model and analytes at various temperatures show that the proposed temperature Compensation Mechanism enhances the performance of the sensor in a significant way. This temperature Compensation strategy could also be implemented in crystals with different topologies.