The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform

Sarah Lewis - One of the best experts on this subject based on the ideXlab platform.

Marla L Clayman - One of the best experts on this subject based on the ideXlab platform.

  • documentation of fertility preservation discussions for young adults with cancer examining Compliance with Treatment guidelines
    Journal of The National Comprehensive Cancer Network, 2016
    Co-Authors: John M Salsman, Betina Yanez, Kristin Smith, Jennifer L Beaumont, Mallory A Snyder, Khouri Barnes, Marla L Clayman
    Abstract:

    BACKGROUND Professional guidelines have been developed to promote discussion between providers and newly diagnosed young adults with cancer about the possibility of cancer Treatment-related infertility, but previous research suggests many young adults fail to receive this information. The aim of this study was to examine rates of and factors predictive of oncologists' Compliance with national guidelines for discussing potential Treatment-related infertility with newly diagnosed young adults with cancer seen at an NCI-designated comprehensive cancer center. METHODS We reviewed data from the electronic medical record for new clinic encounters between medical oncologists and young adults with cancer (ages 18-39 years) from 2010 to 2012. Data from oncologist discussions of fertility preservation were abstracted, as were patient (age, sex, race, ethnicity, cancer type) and oncologist (gender, graduation year from fellowship) characteristics. RESULTS A total of 1,018 cases were reviewed, with 454 patients (mean, 31.5 years; 67.8% women) meeting inclusion criteria. Overall, 83% of patients were informed about potential Treatment-related infertility, with patients with breast cancer (85% informed), Hodgkin lymphoma (95% informed), non-Hodgkin's lymphoma (94% informed), leukemia (88% informed), or testicular cancer (100% informed) more likely to be informed than those with other cancer types (60%-74% informed). There was a significant effect for patient sex (odds ratio, 3.57; CI, 1.33, 9.60; P=.012), with women being more likely to be informed than men. CONCLUSIONS Reported Compliance with fertility preservation guidelines was greater than published rates. Higher Compliance rates in female patients and in patients with cancers more common among young adults may reflect greater awareness of fertility-related concerns among these patients and their providers.

David M Ashley - One of the best experts on this subject based on the ideXlab platform.

  • cancer in adolescents and young adults Treatment and outcome in victoria
    The Medical Journal of Australia, 2004
    Co-Authors: Anne E Mitchell, Deborah L Scarcella, Gemma L Rigutto, Vicky Thursfield, Maree Sexton, Graham G. Giles, David M Ashley
    Abstract:

    Objectives: To describe the location of Treatment, recruitment to clinical trials and outcomes for adolescents and young adults treated for cancer in Victoria. Design and setting: Retrospective review of all adolescents and young adults aged 10–24 years diagnosed with cancer between 1992 and 1996, identified from the Victorian Cancer Registry. Main outcome measures: Treatment regimen (clinical trial, Treatment protocol or neither), Compliance with Treatment and 5-year survival. Results: Questionnaires were completed for 576 of 665 eligible adolescents and young adults (87% response rate). Recruitment into clinical trials decreased with increasing age. Adolescents aged 10–19 years were more likely to be recruited to a clinical trial if treated at a paediatric hospital. For all cancers, 5-year survival was similar across the age groups and was not influenced by the place of Treatment. Only 1% of adolescents and young adults failed to complete planned therapy due to non

Michele R. Hutchison - One of the best experts on this subject based on the ideXlab platform.

  • Time to failure of oral therapy in children with type 2 diabetes: a single center retrospective chart review.
    Pediatric diabetes, 2012
    Co-Authors: Nicole S. Barnes, Perrin C. White, Michele R. Hutchison
    Abstract:

    There are no data in children with type 2 diabetes (T2D) regarding the durability of glycemic control with oral medication. Therefore, we assessed the likelihood of and time to failure of oral therapy in children and adolescents diagnosed with T2D. Charts of patients presenting to our large tertiary-care children's hospital between January 2000 and June 2007 with a new diagnosis of diabetes (n = 1625) were reviewed to identify those with T2D (n = 184). Subjects' initial therapy, hemoglobin A1c (HbA1c), body mass index, age, gender, and antibody status were documented, as well as subsequent therapies and HbA1c values, to determine whether baseline characteristics predicted future insulin dependence. Kaplan-Meier survival curves and Cox proportional hazards analysis demonstrated time to failure of oral therapy. Eighty-nine patients remained on insulin throughout the study. Baseline characteristics that determined future insulin dependence included being placed on insulin initially, initial HbA1c and race (whites less likely to be insulin dependent at study conclusion). Patients who failed oral therapy were more often reported to be non-compliant or unable to tolerate metformin than those who continued on oral therapy. The median time to failure of oral therapy (metformin monotherapy in 84/95) was not significantly different for patients initially treated with oral therapy (42 months) and insulin (35 months). Thus, children with T2D appear to fail oral therapy more quickly than what is reported in adults. It is not yet known if improving Compliance with Treatment might allow more children to remain on oral medications.

John M Kane - One of the best experts on this subject based on the ideXlab platform.

  • an economic review of Compliance with medication therapy in the Treatment of schizophrenia
    Psychiatric Services, 2003
    Co-Authors: Patricia Thieda, Stephen M Beard, Anke Richter, John M Kane
    Abstract:

    OBJECTIVES: The authors examined published economic evaluations of schizophrenia and antipsychotic therapies to determine the role of Compliance with medication therapy in the economic cost of schizophrenia. METHODS: The authors reviewed studies published from 1995 to 2002 that evaluated Compliance with Treatment for schizophrenia. Literature searches were conducted for that period by using MEDLINE, EMBASE, and Current Contents. The primary search terms were "schizophrenia," "Compliance," "relapse," and "economic costs." RESULTS AND CONCLUSIONS: A definitive relationship exists between Compliance and the economic costs of schizophrenia. Lower rates of Compliance lead to higher costs of treating schizophrenia. However, the full implications are difficult to surmise from the literature because of inadequacies in the reporting of Compliance rates and outcomes of Treatment over time. The authors suggest collection of data on longer-term clinical outcomes as a means to improve future economic evaluations of sc...