The Experts below are selected from a list of 16086 Experts worldwide ranked by ideXlab platform
Bruce P Hermann - One of the best experts on this subject based on the ideXlab platform.
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network analysis of prospective brain development in youth with benign epilepsy with centrotemporal spikes and its relationship to cognition
2019Co-Authors: Camille Garciaramos, Kevin Dabbs, Jack J Lin, Jana E Jones, Carl E Stafstrom, David A Hsu, Mary E Meyerand, Vivek Prabhakaran, Bruce P HermannAbstract:Objective Benign epilepsy with centrotemporal spikes (BECTS) is the most common childhood idiopathic localization-related epilepsy syndrome. BECTS presents normal routine magnetic resonance imaging (MRI); however, quantitative analytic techniques have captured subtle cortical and subcortical magnetic resonance anomalies. Network science, including graph theory (GT) analyses, facilitates understanding of brain covariance patterns, potentially informing in important ways how this common self-limiting epilepsy syndrome may impact normal patterns of brain and cognitive development. Methods GT analyses examined the developmental covariance among cortical and subcortical regions in children with new/recent onset BECTS (n = 19) and typically developing healthy controls (n = 22) who underwent high-resolution MRI and cognitive assessment at Baseline and 2 years later. Global (transitivity, global efficiency, and modularity index [Q]) and regional measures (local efficiency and hubs) were investigated to characterize network development in each group. Associations between Baseline-based GT measures and cognition at both time points addressed the implications of GT analyses for cognition and prospective cognitive development. Furthermore, an individual contribution measure was investigated, reflecting how important for cognition it is for BECTS to resemble the correlation matrices of controls. Results Groups exhibited similar Q and overall network Configuration, with BECTS presenting significantly higher transitivity and both global and local efficiency. Furthermore, both groups presented a similar number of hubs, with BECTS showing a higher number in temporal lobe regions compared to controls. The investigated measures were negatively associated with 2-year cognitive outcomes in BECTS. Significance Children with BECTS present a higher-than-normal global developmental Configuration compared to controls, along with divergence from normality in terms of regional Configuration. Baseline GT measures demonstrate potential as a cognitive biomarker to predict cognitive outcome in BECTS 2 years after diagnosis. Similarities and differences in developmental network Configurations and their implications for cognition and behavior across common epilepsy syndromes are of theoretical interest and clinical relevance.
Guang Quan Wang - One of the best experts on this subject based on the ideXlab platform.
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the brief analysis of solutions to automated network equipment security Configuration Baseline verification
2015Co-Authors: Guang Quan WangAbstract:This paper introduces definition, control object and classification of network equipment security Configuration Baseline, analyses the difficulties of security work of the security Configuration Baseline, discusses function demand, the system architecture and the deployment module of the security Configuration Baseline verification , forms basic shape of the solutions to the security Configuration Baseline verification and gives suggestions to improve the security Configuration Baseline indemnification.
Camille Garciaramos - One of the best experts on this subject based on the ideXlab platform.
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network analysis of prospective brain development in youth with benign epilepsy with centrotemporal spikes and its relationship to cognition
2019Co-Authors: Camille Garciaramos, Kevin Dabbs, Jack J Lin, Jana E Jones, Carl E Stafstrom, David A Hsu, Mary E Meyerand, Vivek Prabhakaran, Bruce P HermannAbstract:Objective Benign epilepsy with centrotemporal spikes (BECTS) is the most common childhood idiopathic localization-related epilepsy syndrome. BECTS presents normal routine magnetic resonance imaging (MRI); however, quantitative analytic techniques have captured subtle cortical and subcortical magnetic resonance anomalies. Network science, including graph theory (GT) analyses, facilitates understanding of brain covariance patterns, potentially informing in important ways how this common self-limiting epilepsy syndrome may impact normal patterns of brain and cognitive development. Methods GT analyses examined the developmental covariance among cortical and subcortical regions in children with new/recent onset BECTS (n = 19) and typically developing healthy controls (n = 22) who underwent high-resolution MRI and cognitive assessment at Baseline and 2 years later. Global (transitivity, global efficiency, and modularity index [Q]) and regional measures (local efficiency and hubs) were investigated to characterize network development in each group. Associations between Baseline-based GT measures and cognition at both time points addressed the implications of GT analyses for cognition and prospective cognitive development. Furthermore, an individual contribution measure was investigated, reflecting how important for cognition it is for BECTS to resemble the correlation matrices of controls. Results Groups exhibited similar Q and overall network Configuration, with BECTS presenting significantly higher transitivity and both global and local efficiency. Furthermore, both groups presented a similar number of hubs, with BECTS showing a higher number in temporal lobe regions compared to controls. The investigated measures were negatively associated with 2-year cognitive outcomes in BECTS. Significance Children with BECTS present a higher-than-normal global developmental Configuration compared to controls, along with divergence from normality in terms of regional Configuration. Baseline GT measures demonstrate potential as a cognitive biomarker to predict cognitive outcome in BECTS 2 years after diagnosis. Similarities and differences in developmental network Configurations and their implications for cognition and behavior across common epilepsy syndromes are of theoretical interest and clinical relevance.
Jana E Jones - One of the best experts on this subject based on the ideXlab platform.
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network analysis of prospective brain development in youth with benign epilepsy with centrotemporal spikes and its relationship to cognition
2019Co-Authors: Camille Garciaramos, Kevin Dabbs, Jack J Lin, Jana E Jones, Carl E Stafstrom, David A Hsu, Mary E Meyerand, Vivek Prabhakaran, Bruce P HermannAbstract:Objective Benign epilepsy with centrotemporal spikes (BECTS) is the most common childhood idiopathic localization-related epilepsy syndrome. BECTS presents normal routine magnetic resonance imaging (MRI); however, quantitative analytic techniques have captured subtle cortical and subcortical magnetic resonance anomalies. Network science, including graph theory (GT) analyses, facilitates understanding of brain covariance patterns, potentially informing in important ways how this common self-limiting epilepsy syndrome may impact normal patterns of brain and cognitive development. Methods GT analyses examined the developmental covariance among cortical and subcortical regions in children with new/recent onset BECTS (n = 19) and typically developing healthy controls (n = 22) who underwent high-resolution MRI and cognitive assessment at Baseline and 2 years later. Global (transitivity, global efficiency, and modularity index [Q]) and regional measures (local efficiency and hubs) were investigated to characterize network development in each group. Associations between Baseline-based GT measures and cognition at both time points addressed the implications of GT analyses for cognition and prospective cognitive development. Furthermore, an individual contribution measure was investigated, reflecting how important for cognition it is for BECTS to resemble the correlation matrices of controls. Results Groups exhibited similar Q and overall network Configuration, with BECTS presenting significantly higher transitivity and both global and local efficiency. Furthermore, both groups presented a similar number of hubs, with BECTS showing a higher number in temporal lobe regions compared to controls. The investigated measures were negatively associated with 2-year cognitive outcomes in BECTS. Significance Children with BECTS present a higher-than-normal global developmental Configuration compared to controls, along with divergence from normality in terms of regional Configuration. Baseline GT measures demonstrate potential as a cognitive biomarker to predict cognitive outcome in BECTS 2 years after diagnosis. Similarities and differences in developmental network Configurations and their implications for cognition and behavior across common epilepsy syndromes are of theoretical interest and clinical relevance.
Vivek Prabhakaran - One of the best experts on this subject based on the ideXlab platform.
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network analysis of prospective brain development in youth with benign epilepsy with centrotemporal spikes and its relationship to cognition
2019Co-Authors: Camille Garciaramos, Kevin Dabbs, Jack J Lin, Jana E Jones, Carl E Stafstrom, David A Hsu, Mary E Meyerand, Vivek Prabhakaran, Bruce P HermannAbstract:Objective Benign epilepsy with centrotemporal spikes (BECTS) is the most common childhood idiopathic localization-related epilepsy syndrome. BECTS presents normal routine magnetic resonance imaging (MRI); however, quantitative analytic techniques have captured subtle cortical and subcortical magnetic resonance anomalies. Network science, including graph theory (GT) analyses, facilitates understanding of brain covariance patterns, potentially informing in important ways how this common self-limiting epilepsy syndrome may impact normal patterns of brain and cognitive development. Methods GT analyses examined the developmental covariance among cortical and subcortical regions in children with new/recent onset BECTS (n = 19) and typically developing healthy controls (n = 22) who underwent high-resolution MRI and cognitive assessment at Baseline and 2 years later. Global (transitivity, global efficiency, and modularity index [Q]) and regional measures (local efficiency and hubs) were investigated to characterize network development in each group. Associations between Baseline-based GT measures and cognition at both time points addressed the implications of GT analyses for cognition and prospective cognitive development. Furthermore, an individual contribution measure was investigated, reflecting how important for cognition it is for BECTS to resemble the correlation matrices of controls. Results Groups exhibited similar Q and overall network Configuration, with BECTS presenting significantly higher transitivity and both global and local efficiency. Furthermore, both groups presented a similar number of hubs, with BECTS showing a higher number in temporal lobe regions compared to controls. The investigated measures were negatively associated with 2-year cognitive outcomes in BECTS. Significance Children with BECTS present a higher-than-normal global developmental Configuration compared to controls, along with divergence from normality in terms of regional Configuration. Baseline GT measures demonstrate potential as a cognitive biomarker to predict cognitive outcome in BECTS 2 years after diagnosis. Similarities and differences in developmental network Configurations and their implications for cognition and behavior across common epilepsy syndromes are of theoretical interest and clinical relevance.