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Gregory J. Raugi - One of the best experts on this subject based on the ideXlab platform.

  • Dermatologic Features of the Superior Vena Cava Syndrome
    Archives of dermatology, 1992
    Co-Authors: Jan V. Hirschmann, Gregory J. Raugi
    Abstract:

    • Background.— The superior vena cava syndrome occurs when extrinsic compression or intraluminal occlusion impedes blood flow through this vessel. The most common underlying cause is a malignant neoplasm, especially a bronchogenic carcinoma. This article describes the cutaneous findings of this disorder. Observations.— Among the earliest and most prominent features are numerous, dilated, vertically oriented, and tortuous cutaneous venules or veins above the rib cage margin. Recognition of this cutaneous sign allowed us to make a diagnosis of lung cancer in several patients. Other features include upper body edema and ruddiness or cyanosis, distended neck veins, proptosis, and Conjunctival Suffusion. Conclusions.— Detecting the characteristic cutaneous features can lead to an early diagnosis of the superior vena cava syndrome. These skin changes usually represent indirect dermatologic signs of an underlying malignant neoplasm; for most patients, this syndrome is the initial manifestation of their cancer. The most common cause is a bronchogenic carcinoma, especially the small-cell variety, but others include lymphomas, primary mediastinal tumors, and metastases to the mediastinal lymph nodes from extrathoracic primary tumors, especially breast cancer. Treatment of the underlying malignant neoplasm and relief of the obstruction produce prompt improvement in the dermatologic findings. (Arch Dermatol.1992;128:953-956)

Jan V. Hirschmann - One of the best experts on this subject based on the ideXlab platform.

  • Dermatologic Features of the Superior Vena Cava Syndrome
    Archives of dermatology, 1992
    Co-Authors: Jan V. Hirschmann, Gregory J. Raugi
    Abstract:

    • Background.— The superior vena cava syndrome occurs when extrinsic compression or intraluminal occlusion impedes blood flow through this vessel. The most common underlying cause is a malignant neoplasm, especially a bronchogenic carcinoma. This article describes the cutaneous findings of this disorder. Observations.— Among the earliest and most prominent features are numerous, dilated, vertically oriented, and tortuous cutaneous venules or veins above the rib cage margin. Recognition of this cutaneous sign allowed us to make a diagnosis of lung cancer in several patients. Other features include upper body edema and ruddiness or cyanosis, distended neck veins, proptosis, and Conjunctival Suffusion. Conclusions.— Detecting the characteristic cutaneous features can lead to an early diagnosis of the superior vena cava syndrome. These skin changes usually represent indirect dermatologic signs of an underlying malignant neoplasm; for most patients, this syndrome is the initial manifestation of their cancer. The most common cause is a bronchogenic carcinoma, especially the small-cell variety, but others include lymphomas, primary mediastinal tumors, and metastases to the mediastinal lymph nodes from extrathoracic primary tumors, especially breast cancer. Treatment of the underlying malignant neoplasm and relief of the obstruction produce prompt improvement in the dermatologic findings. (Arch Dermatol.1992;128:953-956)

Gottlieb L. Turnbull - One of the best experts on this subject based on the ideXlab platform.

Chun-ming Lee - One of the best experts on this subject based on the ideXlab platform.

  • doi:10.4269/ajtmh.2012.11-0518 Copyright # 2012 by The American Society of Tropical Medicine and Hygiene Images in Clinical Tropical Medicine
    2016
    Co-Authors: Leptospirosis After Typhoon, Chien-yu Lin, Nan-chang Chiu, Chun-ming Lee
    Abstract:

    Abstract. Leptospirosis is a zoonotic disease with proteanmanifestations. A 35-year-oldmale presented with pneumo-nia after the TyphoonMorakot. Skin rash, Conjunctival Suffusion, and subConjunctival hemorrhage led us to the diagnosis of leptospirosis and the microscopic agglutination test confirmed the diagnosis. This patient well demonstrated the picture of Conjunctival Suffusion and reminded us of the alertness of leptospirosis after a typhoon. An immunocompetent 35-year-old male telecom company employee presentedwith fever andmyalgia in early September 2009, a month after the moderate-strength Typhoon Morakot that caused a heavy rainfall in Taiwan. He was diagnosed with pneumonia with respiratory distress and shock (Figure 1). Intensive care with respiratory and inotropic support and broad-spectrum antibiotics with piperacillin/tazobactam were administered upon admission. He subsequently developed skin rash, Conjunctival Suffusion, and subConjunctival hemor-rhage, which were suggestive of leptospirosis (Figures 2 and 3). Thus, empirical therapy with penicillin þ ceftriaxone wa

  • Leptospirosis after Typhoon
    The American journal of tropical medicine and hygiene, 2012
    Co-Authors: Chien-yu Lin, Nan-chang Chiu, Chun-ming Lee
    Abstract:

    Leptospirosis is a zoonotic disease with protean manifestations. A 35-year-old male presented with pneumonia after the Typhoon Morakot. Skin rash, Conjunctival Suffusion, and subConjunctival hemorrhage led us to the diagnosis of leptospirosis and the microscopic agglutination test confirmed the diagnosis. This patient well demonstrated the picture of Conjunctival Suffusion and reminded us of the alertness of leptospirosis after a typhoon.

  • Images in Clinical Tropical Medicine Leptospirosis after Typhoon
    2012
    Co-Authors: Chien-yu Lin, Nan-chang Chiu, Chun-ming Lee
    Abstract:

    Leptospirosis isazoonotic disease withprotean manifestations. A 35-year-old male presented withpneumo- nia after the Typhoon Morakot. Skin rash, Conjunctival Suffusion, and subConjunctival hemorrhage led us to the diagnosis of leptospirosis and the microscopic agglutination test confirmed the diagnosis. This patient well demonstrated the picture of Conjunctival Suffusion and reminded us of the alertnessof leptospirosis after a typhoon. An immunocompetent 35-year-old male telecom company employeepresentedwithfeverandmyalgiainearlySeptember 2009, a month after the moderate-strength Typhoon Morakot that caused a heavy rainfall in Taiwan. He was diagnosed with pneumonia with respiratory distress and shock (Figure 1). Intensive care with respiratory and inotropic support and broad-spectrum antibiotics with piperacillin/tazobactam were administered upon admission. He subsequently developed skin rash, Conjunctival Suffusion, and subConjunctival hemor- rhage,which were suggestive ofleptospirosis (Figures 2 and 3). Thus, empirical therapy with penicillin þ ceftriaxone was initiated to treat leptospirosis and cover possible bacterial co-infection, although he could have been treated with either

Albert J. Moreno - One of the best experts on this subject based on the ideXlab platform.