The Experts below are selected from a list of 234 Experts worldwide ranked by ideXlab platform
Xiao Lin-rong - One of the best experts on this subject based on the ideXlab platform.
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Tabular design based on three-variable universal-threshold-logic gates.
2020Co-Authors: Xiao Lin-rongAbstract:Based on the discussion of the classification of logical functions,the P classification Table of three-variable functions,input permutation Table and input Connection Table of representative functions of P classification are provided. A tabular design method based on three-variable universal-threshold-logic gates is proposed and several design examples are given.
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OC expansion's tabular design based on three-variable universal-threshold-logic gates
Journal of Zhejiang University of Technology, 2020Co-Authors: Xiao Lin-rongAbstract:Threshold functions and universal-threshold-logic gates have a lot of advantages,but the logic design utilizing universal-threshold-logic gates is much complicated.Based on the discussion of OC expansion and the classification of logical functions,the design of universal-threshold-logic gates is discussed.the P classification Table of three-variable functions,input permutation Table and input Connection Table of representative functions of P classification based on logical function OC are provided.A tabular design method for an arbitrary logic function with OC expansion based on three-variable universal-threshold-logic gates is proposed and several design cases are given.It is shown that this method has many advantages,such as simplicity,intuition and so on.
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CRM expansion's tabular design based on three-variable universal-threshold-logic gates with complementary outputs.
2020Co-Authors: Xiao Lin-rongAbstract:Based on the discussion of CRM expansion,the classification of logical functions and the P classification Table of three-variable functions,input permutation Table and input Connection Table of representative functions of P classification are provided.Based on three-variable universal-threshold-logic gates with complementary outputs,a tabular design method to an arbitrary logic function expressed in CRM expansion is proposed.It is proved by several design examples that the method has many advantages,such as simplicity,intuition and so on.
David G. Lloyd - One of the best experts on this subject based on the ideXlab platform.
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Permuting input for more effective sampling of 3D conformer space
Journal of Computer-Aided Molecular Design, 2006Co-Authors: Gianna Carta, Darren Fayne, Valeria Onnis, Andrew J. S. Knox, David G. LloydAbstract:SMILES strings and other classic 2D structural formats offer a convenient way to represent molecules as a simplistic Connection Table, with the inherent advantages of ease of handling and storage. In the context of virtual screening, chemical databases to be screened are often initially represented by canonicalised SMILES strings that can be filtered and pre-processed in a number of ways, resulting in molecules that occupy similar regions of chemical space to active compounds of a therapeutic target. A wide variety of software exists to convert molecules into SMILES format, namely, Mol2smi (Daylight Inc.), MOE (Chemical Computing Group) and Babel (Openeye Scientific Software). Depending on the algorithm employed, the atoms of a SMILES string defining a molecule can be ordered differently. Upon conversion to 3D coordinates they result in the production of ostensibly the same molecule. In this work we show how different permutations of a SMILES string can affect conformer generation, affecting reliability and repeatability of the results. Furthermore, we propose a novel procedure for the generation of conformers, taking advantage of the permutation of the input strings--both SMILES and other 2D formats, leading to more effective sampling of conformation space in output, and also implementing fingerprint and principal component analyses step to post process and visualise the results.
Pan Wei-zhen - One of the best experts on this subject based on the ideXlab platform.
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Tabular Design Based on Three-Variable Universal-Threshold-Logic Gates
Journal of Southwest China Normal University, 2020Co-Authors: Pan Wei-zhenAbstract:Based on the discussion of RM expansion and the classification of logical functions, the P classification Table of three-variable functions, input permutation Table and input Connection Table of representative functions of P classification are provided.A tabular design method to an arbitrary three-variable function with RM expansion based on three-variable universal-threshold-logic gates is proposed, and several design examples are given.
Gianna Carta - One of the best experts on this subject based on the ideXlab platform.
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Permuting input for more effective sampling of 3D conformer space
Journal of Computer-aided Molecular Design, 2006Co-Authors: Gianna Carta, Darren Fayne, Valeria Onnis, Andrew J. S. Knox, David LloydAbstract:SMILES strings and other classic 2D structural formats offer a convenient way to represent molecules as a simplistic Connection Table, with the inherent advantages of ease of handling and storage. In the context of virtual screening, chemical databases to be screened are often initially represented by canonicalised SMILES strings that can be filtered and pre-processed in a number of ways, resulting in molecules that occupy similar regions of chemical space to active compounds of a therapeutic target. A wide variety of software exists to convert molecules into SMILES format, namely, Mol2smi (Daylight Inc.), MOE (Chemical Computing Group) and Babel (Openeye Scientific Software). Depending on the algorithm employed, the atoms of a SMILES string defining a molecule can be ordered differently. Upon conversion to 3D coordinates they result in the production of ostensibly the same molecule.
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Permuting input for more effective sampling of 3D conformer space
Journal of Computer-Aided Molecular Design, 2006Co-Authors: Gianna Carta, Darren Fayne, Valeria Onnis, Andrew J. S. Knox, David G. LloydAbstract:SMILES strings and other classic 2D structural formats offer a convenient way to represent molecules as a simplistic Connection Table, with the inherent advantages of ease of handling and storage. In the context of virtual screening, chemical databases to be screened are often initially represented by canonicalised SMILES strings that can be filtered and pre-processed in a number of ways, resulting in molecules that occupy similar regions of chemical space to active compounds of a therapeutic target. A wide variety of software exists to convert molecules into SMILES format, namely, Mol2smi (Daylight Inc.), MOE (Chemical Computing Group) and Babel (Openeye Scientific Software). Depending on the algorithm employed, the atoms of a SMILES string defining a molecule can be ordered differently. Upon conversion to 3D coordinates they result in the production of ostensibly the same molecule. In this work we show how different permutations of a SMILES string can affect conformer generation, affecting reliability and repeatability of the results. Furthermore, we propose a novel procedure for the generation of conformers, taking advantage of the permutation of the input strings--both SMILES and other 2D formats, leading to more effective sampling of conformation space in output, and also implementing fingerprint and principal component analyses step to post process and visualise the results.
Song Hong - One of the best experts on this subject based on the ideXlab platform.
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Tabular Design Based on Three-Variable Universal-Threshold-logic Gates with a Complementary Output
Bulletin of Science and Technology, 2020Co-Authors: Song HongAbstract:Based on the discussion of the classification of logical functions,the P classification Table of three-variable functions,input permutation Table and i nput Connection Table of representative functions of P classification are provid ed.A tabular design method based on three-variable universal-threshold-logic gat es with a complementary output is proposed and several design examples are given.