The Experts below are selected from a list of 50535 Experts worldwide ranked by ideXlab platform
Paul S Sidhu - One of the best experts on this subject based on the ideXlab platform.
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Characterization of a hepatic haemangioma with Contrast-Enhanced Ultrasound in an infant:
Ultrasound (Leeds England), 2017Co-Authors: Marta Anna Piorkowska, Rok Dezman, Maria E. Sellars, Annamaria Deganello, Paul S SidhuAbstract:Focal liver lesions are uncommon in the paediatric population, majority are benign but need to be clearly identified as benign. Contrast-Enhanced Ultrasound has recently received approval for paediatric hepatic use and represents an inexpensive and safe alternative to computed tomography and magnetic resonance imaging for focal liver lesion characterization. We report a case of an incidental focal liver lesion in a four-month-old infant, indeterminate on B-mode Ultrasound but successfully characterized with Contrast-Enhanced Ultrasound as a haemangioma, without recourse to other imaging techniques, and with minimal patient discomfort.
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Microbubble Contrast-Enhanced Ultrasound in liver transplantation.
European radiology, 2004Co-Authors: Jonathan D Berry, Paul S SidhuAbstract:The use of liver transplantation for treatment of end-stage liver disease is now commonplace. The accurate assessment of the pre-transplant candidate and long-term follow-up of the posttransplant patient is vital in ensuring that the limited resource of donor livers is appropriately used. Ultrasound is accepted as playing an important role in this process. The advent of microbubble contrast enhanced Ultrasound provides new opportunities in terms of improving diagnostic accuracy and obviating more invasive investigations with their associated patient morbidity and mortality. We present the current and developing applications of microbubble Contrast-Enhanced Ultrasound in the field of liver transplantation.
Jonathan D Berry - One of the best experts on this subject based on the ideXlab platform.
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Microbubble Contrast-Enhanced Ultrasound in liver transplantation.
European radiology, 2004Co-Authors: Jonathan D Berry, Paul S SidhuAbstract:The use of liver transplantation for treatment of end-stage liver disease is now commonplace. The accurate assessment of the pre-transplant candidate and long-term follow-up of the posttransplant patient is vital in ensuring that the limited resource of donor livers is appropriately used. Ultrasound is accepted as playing an important role in this process. The advent of microbubble contrast enhanced Ultrasound provides new opportunities in terms of improving diagnostic accuracy and obviating more invasive investigations with their associated patient morbidity and mortality. We present the current and developing applications of microbubble Contrast-Enhanced Ultrasound in the field of liver transplantation.
Ethan J Halpern - One of the best experts on this subject based on the ideXlab platform.
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Contrast-Enhanced Ultrasound imaging of prostate cancer.
Reviews in urology, 2006Co-Authors: Ethan J HalpernAbstract:Ultrasound imaging of the prostate is commonly used to assess the size of the gland and for needle placement during systematic biopsy. Ultrasound evaluation of prostate cancer is limited by difficulty in distinguishing benign from malignant tissue. Although Doppler techniques may provide some improvement in the detection of prostate cancer, targeted biopsy based on conventional Ultrasound with Doppler is not sufficient to replace systematic biopsy. Contrast-Enhanced Ultrasound imaging techniques that employ microbubble contrast agents represent an innovative approach to imaging of the neovascularity associated with prostate cancer. This review describes the application of Contrast-Enhanced Ultrasound to improve detection and assessment of prostate cancer.
Hessel Wijkstra - One of the best experts on this subject based on the ideXlab platform.
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Contrast-Enhanced Ultrasound tractography for 3D vascular imaging of the prostate.
Scientific reports, 2018Co-Authors: Ruud J. G. Van Sloun, Arnoud W Postema, Libertario Demi, Stefan G. Schalk, Cristina Caresio, Christophe K. Mannaerts, Filippo Molinari, Hans Van Der Linden, Pingtong Huang, Hessel WijkstraAbstract:Diffusion tensor tractography (DTT) enables visualization of fiber trajectories in soft tissue using magnetic resonance imaging. DTT exploits the anisotropic nature of water diffusion in fibrous structures to identify diffusion pathways by generating streamlines based on the principal diffusion vector. Anomalies in these pathways can be linked to neural deficits. In a different field, Contrast-Enhanced Ultrasound is used to assess anomalies in blood flow with the aim of locating cancer-induced angiogenesis. Like water diffusion, blood flow and transport of contrast agents also shows a principal direction; however, this is now determined by the local vasculature. Here we show how the tractographic techniques developed for magnetic resonance imaging DTT can be translated to Contrast-Enhanced Ultrasound, by first estimating contrast flow velocity fields from Contrast-Enhanced Ultrasound acquisitions, and then applying tractography. We performed 4D in-vivo Contrast-Enhanced Ultrasound of three human prostates, proving the feasibility of the proposed approach with clinically acquired datasets. By comparing the results to histopathology after prostate resection, we observed qualitative agreement between the contrast flow tracts and typical markers of cancer angiogenic microvasculature: higher densities and tortuous geometries in tumor areas. The method can be used in-vivo using a standard Contrast-Enhanced Ultrasound protocol, opening up new possibilities in the area of vascular characterization for cancer diagnostics.
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Multiparametric dynamic Contrast-Enhanced Ultrasound imaging of prostate cancer
European Radiology, 2016Co-Authors: Rogier R. Wildeboer, Mpj Maarten Kuenen, Arnoud W Postema, Libertario Demi, Hessel Wijkstra, Massimo MischiAbstract:Objectives The aim of this study is to improve the accuracy of dynamic Contrast-Enhanced Ultrasound (DCE-US) for prostate cancer (PCa) localization by means of a multiparametric approach.
Arnoud W Postema - One of the best experts on this subject based on the ideXlab platform.
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Contrast-Enhanced Ultrasound tractography for 3D vascular imaging of the prostate.
Scientific reports, 2018Co-Authors: Ruud J. G. Van Sloun, Arnoud W Postema, Libertario Demi, Stefan G. Schalk, Cristina Caresio, Christophe K. Mannaerts, Filippo Molinari, Hans Van Der Linden, Pingtong Huang, Hessel WijkstraAbstract:Diffusion tensor tractography (DTT) enables visualization of fiber trajectories in soft tissue using magnetic resonance imaging. DTT exploits the anisotropic nature of water diffusion in fibrous structures to identify diffusion pathways by generating streamlines based on the principal diffusion vector. Anomalies in these pathways can be linked to neural deficits. In a different field, Contrast-Enhanced Ultrasound is used to assess anomalies in blood flow with the aim of locating cancer-induced angiogenesis. Like water diffusion, blood flow and transport of contrast agents also shows a principal direction; however, this is now determined by the local vasculature. Here we show how the tractographic techniques developed for magnetic resonance imaging DTT can be translated to Contrast-Enhanced Ultrasound, by first estimating contrast flow velocity fields from Contrast-Enhanced Ultrasound acquisitions, and then applying tractography. We performed 4D in-vivo Contrast-Enhanced Ultrasound of three human prostates, proving the feasibility of the proposed approach with clinically acquired datasets. By comparing the results to histopathology after prostate resection, we observed qualitative agreement between the contrast flow tracts and typical markers of cancer angiogenic microvasculature: higher densities and tortuous geometries in tumor areas. The method can be used in-vivo using a standard Contrast-Enhanced Ultrasound protocol, opening up new possibilities in the area of vascular characterization for cancer diagnostics.
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Multiparametric dynamic Contrast-Enhanced Ultrasound imaging of prostate cancer
European Radiology, 2016Co-Authors: Rogier R. Wildeboer, Mpj Maarten Kuenen, Arnoud W Postema, Libertario Demi, Hessel Wijkstra, Massimo MischiAbstract:Objectives The aim of this study is to improve the accuracy of dynamic Contrast-Enhanced Ultrasound (DCE-US) for prostate cancer (PCa) localization by means of a multiparametric approach.