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M Bollow - One of the best experts on this subject based on the ideXlab platform.

  • rheumatoid arthritis of the shoulder joint comparison of Conventional Radiography ultrasound and dynamic contrast enhanced magnetic resonance imaging
    Arthritis & Rheumatism, 2003
    Co-Authors: Kaygeert A Hermann, M Backhaus, Udo Schneider, Karsten Labs, Dieter Loreck, Svenda Zuhlsdorf, Tania Schink, Thomas Fischer, Bernd Hamm, M Bollow
    Abstract:

    Objective To determine the role of ultrasound and magnetic resonance imaging (MRI) compared with Conventional Radiography in the detection of chronic and acute inflammatory manifestations of rheumatoid arthritis (RA) of the shoulder joint. Methods Forty-three consecutive patients with known RA prospectively underwent clinical examination, Radiography, ultrasound, and MRI of the shoulder joints. Each patient was assigned a clinical/laboratory score consisting of 7 parameters, including measurements of shoulder mobility, the erythrocyte sedimentation rate, and C-reactive protein level. Conventional Radiography was standardized and performed in 2 planes. Ultrasound was performed in 10 predefined planes using a 7.5-MHz linear transducer. MRI at 1.5T comprised transverse and oblique coronal T1- and T2*-weighted fast spin-echo, gradient-echo (GRE), and inversion-recovery sequences with a matrix size of up to 512 pixels. A dynamic T1-weighted GRE sequence was acquired with intravenous administration of contrast medium. Erosions were assessed using all 3 imaging techniques on a 4-point scale. Soft-tissue involvement was evaluated according to the presence of synovitis, tenosynovitis, and bursitis on ultrasound and MRI. The results in the study group were compared with those obtained in a control group of 10 patients with shoulder pain. Results In the study group, erosions of the humeroscapular joint were detected by Conventional Radiography in 26 patients, by ultrasound in 30 patients, and by MRI in 39 patients; the differences were statistically significant for the comparisons of Conventional Radiography with MRI and for ultrasound versus MRI (P < 0.0001). Conventional Radiography detected 12 erosions of the scapula and MRI detected 15. Synovitis was demonstrated in 12 patients by ultrasound and in 27 patients by MRI (P = 0.0003). Tenosynovitis was observed in 15 patients by ultrasound and in 28 patients by MRI (P = 0.0064). Bursitis was detected in 13 patients by ultrasound and in 18 patients by MRI. The findings on dynamic contrast-enhanced MRI correlated significantly with the detection of synovitis by ultrasound and erosions by static MRI (P < 0.05). Conclusion Ultrasound and MRI supplement Conventional Radiography in assessing the shoulder joint. Although Conventional Radiography can be used as the sole method of following up known joint destruction in RA, ultrasound and, preferably, MRI are recommended as additional techniques in the initial diagnostic evaluation when Radiography yields negative results.

  • arthritis of the finger joints a comprehensive approach comparing Conventional Radiography scintigraphy ultrasound and contrast enhanced magnetic resonance imaging
    Arthritis & Rheumatism, 1999
    Co-Authors: M Backhaus, Dieter Loreck, Bernd Hamm, Thomas Kamradt, D Sandrock, J Fritz, K J Wolf, H Raber, Gerdrudiger Burmester, M Bollow
    Abstract:

    Objective A prospective study was performed comparing Conventional Radiography, 3-phase bone scintigraphy, ultrasound, and magnetic resonance imaging (MRI) with precontrast and dynamic postcontrast examinations in 60 patients with various forms of arthritis including rheumatoid arthritis (RA), spondylarthropathy, and arthritis associated with connective tissue disease. Methods A total of 840 finger joints were examined clinically and by all 4 imaging methods. Experienced investigators blinded to the clinical findings and diagnoses analyzed all methods independently of each other. The patients were divided into 2 groups. Group 1 included 32 patients (448 finger joints) without radiologic signs of destructive arthritis (Larsen grades 0–1) of the evaluated hand and wrist and group 2 included 28 patients (392 finger joints) with radiographs revealing erosions (Larsen grade 2) of the evaluated hand and/or wrist. Results Clinical evaluation, scintigraphy, MRI, and ultrasound were each more sensitive than Conventional Radiography in detecting inflammatory soft tissue lesions as well as destructive joint processes in arthritis patients in group 1. All differences were statistically significant. We found ultrasound to be even more sensitive than MRI in the detection of synovitis. MRI detected erosions in 92 finger joints (20%; 26 patients) in group 1 that had not been detected by Conventional Radiography. Conclusion Our data indicate that MRI and ultrasound are valuable diagnostic methods in patients with arthritis who have normal findings on radiologic evaluation.

Mikkel Ostergaard - One of the best experts on this subject based on the ideXlab platform.

  • ultrasonography of the metatarsophalangeal joints in rheumatoid arthritis comparison with magnetic resonance imaging Conventional Radiography and clinical examination
    Arthritis & Rheumatism, 2004
    Co-Authors: Marcin Szkudlarek, Eva Narvestad, Mette Klarlund, Michel Courtpayen, Henrik S Thomsen, Mikkel Ostergaard
    Abstract:

    Objective To compare ultrasonography (US) with magnetic resonance imaging (MRI), Conventional Radiography, and clinical examination in the evaluation of bone destruction and signs of inflammation in the metatarsophalangeal (MTP) joints of patients with rheumatoid arthritis (RA). Methods Two hundred MTP joints of 40 patients with RA and 100 MTP joints of 20 healthy control subjects were assessed with B-mode US, contrast-enhanced MRI, Conventional Radiography, and clinical examination for signs of bone destruction and joint inflammation. Results With MRI considered the reference method, the sensitivity, specificity, and accuracy of US for the detection of bone erosions were 0.79, 0.97, and 0.96, respectively, while the corresponding values for Radiography were 0.32, 0.98, and 0.93. The sensitivity, specificity, and accuracy of US for the detection of synovitis were 0.87, 0.74, and 0.79, while for clinical examination, the corresponding values were 0.43, 0.89, and 0.71. Erosive disease was identified in 26 patients by US, compared with 20 patients by MRI and 11 patients by Radiography. Evaluation by US indicated signs of inflammation in 36 patients, while MRI and clinical examination revealed signs of inflammation in 31 patients and 20 patients, respectively. US and MRI volume-based gradings of synovitis showed intraclass correlation coefficients of 0.56–0.72 (P < 0.0001). The MRI and radiographic visualizations of US-detected bone changes were closely related to their size-based gradings on US. Conclusion US enables detection and grading of destructive and inflammatory changes in the MTP joints of patients with RA. By comparison with MRI, US was found to be markedly more sensitive and accurate than clinical examination and Conventional Radiography. Considering the early and frequent involvement of the MTP joints, evaluation of these joints by US may be of major clinical importance in RA.

  • ultrasonography of the metatarsophalangeal joints in rheumatoid arthritis comparison with magnetic resonance imaging Conventional Radiography and clinical examination
    Arthritis & Rheumatism, 2004
    Co-Authors: Marcin Szkudlarek, Eva Narvestad, Mette Klarlund, Michel Courtpayen, Henrik S Thomsen, Mikkel Ostergaard
    Abstract:

    Objective To compare ultrasonography (US) with magnetic resonance imaging (MRI), Conventional Radiography, and clinical examination in the evaluation of bone destruction and signs of inflammation in the metatarsophalangeal (MTP) joints of patients with rheumatoid arthritis (RA). Methods Two hundred MTP joints of 40 patients with RA and 100 MTP joints of 20 healthy control subjects were assessed with B-mode US, contrast-enhanced MRI, Conventional Radiography, and clinical examination for signs of bone destruction and joint inflammation. Results With MRI considered the reference method, the sensitivity, specificity, and accuracy of US for the detection of bone erosions were 0.79, 0.97, and 0.96, respectively, while the corresponding values for Radiography were 0.32, 0.98, and 0.93. The sensitivity, specificity, and accuracy of US for the detection of synovitis were 0.87, 0.74, and 0.79, while for clinical examination, the corresponding values were 0.43, 0.89, and 0.71. Erosive disease was identified in 26 patients by US, compared with 20 patients by MRI and 11 patients by Radiography. Evaluation by US indicated signs of inflammation in 36 patients, while MRI and clinical examination revealed signs of inflammation in 31 patients and 20 patients, respectively. US and MRI volume-based gradings of synovitis showed intraclass correlation coefficients of 0.56–0.72 (P < 0.0001). The MRI and radiographic visualizations of US-detected bone changes were closely related to their size-based gradings on US. Conclusion US enables detection and grading of destructive and inflammatory changes in the MTP joints of patients with RA. By comparison with MRI, US was found to be markedly more sensitive and accurate than clinical examination and Conventional Radiography. Considering the early and frequent involvement of the MTP joints, evaluation of these joints by US may be of major clinical importance in RA.

Marcin Szkudlarek - One of the best experts on this subject based on the ideXlab platform.

  • ultrasonography of the metatarsophalangeal joints in rheumatoid arthritis comparison with magnetic resonance imaging Conventional Radiography and clinical examination
    Arthritis & Rheumatism, 2004
    Co-Authors: Marcin Szkudlarek, Eva Narvestad, Mette Klarlund, Michel Courtpayen, Henrik S Thomsen, Mikkel Ostergaard
    Abstract:

    Objective To compare ultrasonography (US) with magnetic resonance imaging (MRI), Conventional Radiography, and clinical examination in the evaluation of bone destruction and signs of inflammation in the metatarsophalangeal (MTP) joints of patients with rheumatoid arthritis (RA). Methods Two hundred MTP joints of 40 patients with RA and 100 MTP joints of 20 healthy control subjects were assessed with B-mode US, contrast-enhanced MRI, Conventional Radiography, and clinical examination for signs of bone destruction and joint inflammation. Results With MRI considered the reference method, the sensitivity, specificity, and accuracy of US for the detection of bone erosions were 0.79, 0.97, and 0.96, respectively, while the corresponding values for Radiography were 0.32, 0.98, and 0.93. The sensitivity, specificity, and accuracy of US for the detection of synovitis were 0.87, 0.74, and 0.79, while for clinical examination, the corresponding values were 0.43, 0.89, and 0.71. Erosive disease was identified in 26 patients by US, compared with 20 patients by MRI and 11 patients by Radiography. Evaluation by US indicated signs of inflammation in 36 patients, while MRI and clinical examination revealed signs of inflammation in 31 patients and 20 patients, respectively. US and MRI volume-based gradings of synovitis showed intraclass correlation coefficients of 0.56–0.72 (P < 0.0001). The MRI and radiographic visualizations of US-detected bone changes were closely related to their size-based gradings on US. Conclusion US enables detection and grading of destructive and inflammatory changes in the MTP joints of patients with RA. By comparison with MRI, US was found to be markedly more sensitive and accurate than clinical examination and Conventional Radiography. Considering the early and frequent involvement of the MTP joints, evaluation of these joints by US may be of major clinical importance in RA.

  • ultrasonography of the metatarsophalangeal joints in rheumatoid arthritis comparison with magnetic resonance imaging Conventional Radiography and clinical examination
    Arthritis & Rheumatism, 2004
    Co-Authors: Marcin Szkudlarek, Eva Narvestad, Mette Klarlund, Michel Courtpayen, Henrik S Thomsen, Mikkel Ostergaard
    Abstract:

    Objective To compare ultrasonography (US) with magnetic resonance imaging (MRI), Conventional Radiography, and clinical examination in the evaluation of bone destruction and signs of inflammation in the metatarsophalangeal (MTP) joints of patients with rheumatoid arthritis (RA). Methods Two hundred MTP joints of 40 patients with RA and 100 MTP joints of 20 healthy control subjects were assessed with B-mode US, contrast-enhanced MRI, Conventional Radiography, and clinical examination for signs of bone destruction and joint inflammation. Results With MRI considered the reference method, the sensitivity, specificity, and accuracy of US for the detection of bone erosions were 0.79, 0.97, and 0.96, respectively, while the corresponding values for Radiography were 0.32, 0.98, and 0.93. The sensitivity, specificity, and accuracy of US for the detection of synovitis were 0.87, 0.74, and 0.79, while for clinical examination, the corresponding values were 0.43, 0.89, and 0.71. Erosive disease was identified in 26 patients by US, compared with 20 patients by MRI and 11 patients by Radiography. Evaluation by US indicated signs of inflammation in 36 patients, while MRI and clinical examination revealed signs of inflammation in 31 patients and 20 patients, respectively. US and MRI volume-based gradings of synovitis showed intraclass correlation coefficients of 0.56–0.72 (P < 0.0001). The MRI and radiographic visualizations of US-detected bone changes were closely related to their size-based gradings on US. Conclusion US enables detection and grading of destructive and inflammatory changes in the MTP joints of patients with RA. By comparison with MRI, US was found to be markedly more sensitive and accurate than clinical examination and Conventional Radiography. Considering the early and frequent involvement of the MTP joints, evaluation of these joints by US may be of major clinical importance in RA.

Daichi Hayashi - One of the best experts on this subject based on the ideXlab platform.

  • imaging of osteoarthritis by Conventional Radiography mr imaging pet computed tomography and pet mr imaging
    Pet Clinics, 2019
    Co-Authors: Frank W. Roemer, Daichi Hayashi, Ali Guermazi
    Abstract:

    Radiography remains the first-line imaging tool to characterize structural changes of osteoarthritis (OA) in both clinical and research settings, but MRI continues to play a large role in OA research. Compositional MRI enables evaluation of the biochemical properties of joint tissues, allowing assessment of early "premorphologic" changes that cannot be depicted on Conventional MRI Hybrid PET-CT and PET-MRI allow integration of high-resolution structural information on CT and MRI with metabolic information obtained from PET related to OA disease process. We describe OA imaging by means of Conventional Radiography, MRI PET-CT, and PET-MRI.

  • Conventional Radiography as an Indirect Measure for Cartilage Pathology
    Cartilage Imaging, 2011
    Co-Authors: Daichi Hayashi, Frank W. Roemer, Jeffrey Duryea, Ali Guermazi
    Abstract:

    Conventional Radiography is the simplest and least expensive method for imaging joints affected by various joint pathologies. Radiographs have been widely used to assess structural changes associated with osteoarthritis (OA). Radiography is used in clinical practice in patients to establish the diagnosis of OA and to monitor the progression of the disease. Strengths of Radiography include its ability to clearly visualize bony features, such as marginal osteophytes, subchondral sclerosis, and subchondral cysts that are associated with OA. Although direct visualization of cartilage is not possible, it can provide an indirect estimate of cartilage thickness and meniscal integrity by the interbone distance or joint space width (JSW). Assessment of OA severity mainly relies on joint space narrowing (JSN) and subchondral bone lesions. Increase in JSN is the most commonly used criterion for the longitudinal assessment of OA progression and the complete loss of JSW, characterized by bone-on-bone contact, is one of the factors considered in the decision for joint replacement [1].

  • Detection of marginal osteophytes and their association with pain: diagnostic performance of digital tomosynthesis compared with Conventional Radiography
    2011
    Co-Authors: Ali Guermazi, Daichi Hayashi, David J. Hunter, Nii-kabu Kabutey, F.w. Roemer
    Abstract:

    Poster: "ECR 2011 / C-0303 / Detection of marginal osteophytes and their association with pain: diagnostic performance of digital tomosynthesis compared with Conventional Radiography" by: "A. Guermazi, D. Hayashi, D. J. Hunter, L. Li, N.-K. Kabutey, F. W. Roemer; Boston, MA/US"

Angelo Ravelli - One of the best experts on this subject based on the ideXlab platform.

  • Magnetic resonance imaging, ultrasonography, and Conventional Radiography in the assessment of bone erosions in juvenile idiopathic arthritis.
    Arthritis & Rheumatism, 2008
    Co-Authors: Clara Malattia, Maria Beatrice Damasio, Francesca Magnaguagno, Angela Pistorio, Maura Valle, Carlo Martinoli, Stefania Viola, Antonella Buoncompagni, Anna Loy, Angelo Ravelli
    Abstract:

    Objective To compare magnetic resonance imaging (MRI), Conventional Radiography, and ultrasonography in identifying bone erosions in patients with juvenile idiopathic arthritis (JIA), and to determine the validity and reliability of an MRI scale in detecting and grading joint damage. Methods In 26 JIA patients, the clinically more affected wrist was studied with MRI, Radiography, and ultrasonography, coupled with standard clinical assessment and biochemical analysis. MR images were assessed independently by 2 readers according to an apposite devised scoring system. Results Of 26 patients, 25 (96.1%) had 1 or more erosions as detected by MRI, whereas Conventional Radiography and ultrasonography revealed erosions in 13 (50%) of 26 and 12 (50%) of 24 patients, respectively. The ability of MRI to detect erosive changes was significantly higher with respect to Conventional Radiography (P = 0.002 with Bonferroni correction [PB]) and ultrasonography (PB = 0.0002) in the group of patients with

  • magnetic resonance imaging ultrasonography and Conventional Radiography in the assessment of bone erosions in juvenile idiopathic arthritis
    Arthritis Care and Research, 2008
    Co-Authors: Clara Malattia, Maria Beatrice Damasio, Francesca Magnaguagno, Angela Pistorio, Maura Valle, Carlo Martinoli, Stefania Viola, Antonella Buoncompagni, Anna Loy, Angelo Ravelli
    Abstract:

    Objective To compare magnetic resonance imaging (MRI), Conventional Radiography, and ultrasonography in identifying bone erosions in patients with juvenile idiopathic arthritis (JIA), and to determine the validity and reliability of an MRI scale in detecting and grading joint damage. Methods In 26 JIA patients, the clinically more affected wrist was studied with MRI, Radiography, and ultrasonography, coupled with standard clinical assessment and biochemical analysis. MR images were assessed independently by 2 readers according to an apposite devised scoring system. Results Of 26 patients, 25 (96.1%) had 1 or more erosions as detected by MRI, whereas Conventional Radiography and ultrasonography revealed erosions in 13 (50%) of 26 and 12 (50%) of 24 patients, respectively. The ability of MRI to detect erosive changes was significantly higher with respect to Conventional Radiography (P = 0.002 with Bonferroni correction [PB]) and ultrasonography (PB = 0.0002) in the group of patients with <3 years' disease duration. Ultrasonography and Conventional Radiography were of equivalent value for the detection of destructive changes. Wrist MRI score correlated highly with radiographic erosion score (rs = 0.82) and with wrist limited range of motion score (rs = 0.69). The interreader intraclass correlation coefficient (ICC) for MRI score was excellent (0.97); intrareader ICCs were good for both investigators (0.97 and 0.79). Conclusion MRI seems to be a powerful tool to detect early structural damage in JIA. The proposed MRI scale for bone erosions appears promising in terms of reliability and construct validity. The pathophysiologic meaning and the prognostic value of bone erosions revealed only by MRI remain to be established in longitudinal studies.