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Young Bae Kim - One of the best experts on this subject based on the ideXlab platform.
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A prospective randomized trial of EUS-guided tissue acquisition using a 25-gauge Core Biopsy Needle with and without a stylet
Surgical Endoscopy, 2018Co-Authors: Min Jae Yang, Jae Chul Hwang, Byung Moo Yoo, Jin Hong Kim, Dakeun Lee, Hyunee Lim, Young Bae KimAbstract:Background Endoscopic ultrasound (EUS)-guided tissue acquisition has become the most effective method of obtaining specimens from a solid lesion adjacent to the gastrointestinal tract. No data exist regarding the use of a stylet in the Core Biopsy Needle during EUS-guided tissue acquisition. The aims of this study were to evaluate the feasibility, safety, and diagnostic yield of a 25-gauge Core Biopsy Needle without (S−) a stylet and to compare its performance with that of a 25-gauge Core Biopsy Needle with (S+) a stylet in patients with solid lesions adjacent to the gastrointestinal tract. Methods From November 2013 to January 2016, we performed 114 EUS-guided tissue acquisitions for the diagnosis of solid lesions adjacent to the gastrointestinal tract in a randomized controlled trial. Patients were randomly assigned to the S+ group ( n = 57) or the S− group ( n = 57). EUS-guided tissue acquisition was performed using a 25-gauge Core Biopsy Needle without an on-site cytopathologist. Results There were no significant differences in technical success (100 vs. 100%, p = 1.000), the mean number of Needle passes (7.0 ± 1.6 vs. 6.8 ± 1.5, p = 0.556), Needle malfunction (0 vs. 1.8%, p = 1.000), or complications (1.8 vs. 0%, p = 1.000) between the S+ and S− groups. Both groups exhibited comparable outcomes with respect to cytological diagnostic accuracy (93.0 vs. 91.2%, p = 1.000) and histological diagnostic accuracy (86.0 vs. 87.7%, p = 1.000) for malignancy. The procedure time was significantly shorter in the S− group than in the S+ group (32.4 ± 11.7 vs. 39.7 ± 8.6 min, p
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A prospective randomized trial of EUS-guided tissue acquisition using a 25-gauge Core Biopsy Needle with and without a stylet
Surgical endoscopy, 2018Co-Authors: Min Jae Yang, Jae Chul Hwang, Byung Moo Yoo, Jin Hong Kim, Dakeun Lee, Hyunee Lim, Young Bae KimAbstract:Background Endoscopic ultrasound (EUS)-guided tissue acquisition has become the most effective method of obtaining specimens from a solid lesion adjacent to the gastrointestinal tract. No data exist regarding the use of a stylet in the Core Biopsy Needle during EUS-guided tissue acquisition. The aims of this study were to evaluate the feasibility, safety, and diagnostic yield of a 25-gauge Core Biopsy Needle without (S−) a stylet and to compare its performance with that of a 25-gauge Core Biopsy Needle with (S+) a stylet in patients with solid lesions adjacent to the gastrointestinal tract.
Min Jae Yang - One of the best experts on this subject based on the ideXlab platform.
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A prospective randomized trial of EUS-guided tissue acquisition using a 25-gauge Core Biopsy Needle with and without a stylet
Surgical Endoscopy, 2018Co-Authors: Min Jae Yang, Jae Chul Hwang, Byung Moo Yoo, Jin Hong Kim, Dakeun Lee, Hyunee Lim, Young Bae KimAbstract:Background Endoscopic ultrasound (EUS)-guided tissue acquisition has become the most effective method of obtaining specimens from a solid lesion adjacent to the gastrointestinal tract. No data exist regarding the use of a stylet in the Core Biopsy Needle during EUS-guided tissue acquisition. The aims of this study were to evaluate the feasibility, safety, and diagnostic yield of a 25-gauge Core Biopsy Needle without (S−) a stylet and to compare its performance with that of a 25-gauge Core Biopsy Needle with (S+) a stylet in patients with solid lesions adjacent to the gastrointestinal tract. Methods From November 2013 to January 2016, we performed 114 EUS-guided tissue acquisitions for the diagnosis of solid lesions adjacent to the gastrointestinal tract in a randomized controlled trial. Patients were randomly assigned to the S+ group ( n = 57) or the S− group ( n = 57). EUS-guided tissue acquisition was performed using a 25-gauge Core Biopsy Needle without an on-site cytopathologist. Results There were no significant differences in technical success (100 vs. 100%, p = 1.000), the mean number of Needle passes (7.0 ± 1.6 vs. 6.8 ± 1.5, p = 0.556), Needle malfunction (0 vs. 1.8%, p = 1.000), or complications (1.8 vs. 0%, p = 1.000) between the S+ and S− groups. Both groups exhibited comparable outcomes with respect to cytological diagnostic accuracy (93.0 vs. 91.2%, p = 1.000) and histological diagnostic accuracy (86.0 vs. 87.7%, p = 1.000) for malignancy. The procedure time was significantly shorter in the S− group than in the S+ group (32.4 ± 11.7 vs. 39.7 ± 8.6 min, p
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A prospective randomized trial of EUS-guided tissue acquisition using a 25-gauge Core Biopsy Needle with and without a stylet
Surgical endoscopy, 2018Co-Authors: Min Jae Yang, Jae Chul Hwang, Byung Moo Yoo, Jin Hong Kim, Dakeun Lee, Hyunee Lim, Young Bae KimAbstract:Background Endoscopic ultrasound (EUS)-guided tissue acquisition has become the most effective method of obtaining specimens from a solid lesion adjacent to the gastrointestinal tract. No data exist regarding the use of a stylet in the Core Biopsy Needle during EUS-guided tissue acquisition. The aims of this study were to evaluate the feasibility, safety, and diagnostic yield of a 25-gauge Core Biopsy Needle without (S−) a stylet and to compare its performance with that of a 25-gauge Core Biopsy Needle with (S+) a stylet in patients with solid lesions adjacent to the gastrointestinal tract.
Manu Nayar - One of the best experts on this subject based on the ideXlab platform.
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Comparison of the diagnostic performance of 2 Core Biopsy Needles for EUS-guided tissue acquisition from solid pancreatic lesions
Gastrointestinal endoscopy, 2016Co-Authors: Manu Nayar, Bharat Paranandi, Muhammad F. Dawwas, John S. Leeds, Antony Darne, Beate Haugk, D Majumdar, Muna M. Ahmed, Kofi OppongAbstract:Background and Aims A new Core Biopsy Needle with a novel tip, opposing bevel, and sheath design has recently been introduced for EUS-guided fine-Needle Biopsy (FNB). The diagnostic utility of this Needle for differentiating solid pancreatic masses is currently unknown. The aim of this study was to compare the diagnostic performance and yield for tissue acquisition from solid pancreatic lesions of the opposing bevel Needle with those of a reverse bevel EUS-FNB Needle. Methods Consecutive patients with solid pancreatic masses undergoing EUS-FNB using the opposing bevel (n = 101) and the reverse bevel (n = 100) Core Biopsy Needles were included in the study. Final diagnosis was based on positive histology or at least 12 months of follow-up in cases with a negative Biopsy. The primary outcome was the diagnostic performance of the 2 Needles for malignant pancreatic masses. A secondary outcome was the diagnostic yield. Results Compared with the reverse bevel Needle, using strict criteria the opposing bevel Needle provided significantly higher sensitivity (71.1% vs 90.1%; P = .0006) and overall accuracy (74% vs 92%; I = 0.0006) for discriminating malignant from benign solid pancreatic masses. The proportion of samples classified as adequate for histologic analysis was 87% for the reverse bevel Needle versus 99% for the opposing bevel Needle ( p = 0.002) Multivariate analysis controlling the Needle gauge and site did not show any significant difference in accuracy and sensitivity between the 2 groups. There were no adverse events in either group. Conclusions In this first, large, single-center preliminary cohort study, an EUS Core Biopsy Needle with a novel tip, opposing bevel, and sheath design afforded substantially superior tissue yield and diagnostic performance compared with a reverse-bevel Needle. If replicated by randomized controlled trials, our findings suggest that similarly designed Needles could become the standard of care for EUS-guided tissue acquisition from solid pancreatic masses.
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Comparison of Diagnostic Performance Between Two Core Biopsy Needles for Endoscopic Ultrasound-Guided Tissue Acquisition of Solid Pancreatic Lesions
Gut, 2016Co-Authors: Bharat Paranandi, Kofi Oppong, Muhammad F. Dawwas, John S. Leeds, Antony Darne, Beate Haugk, D Majumdar, Mm Ahmed, Manu NayarAbstract:Introduction A new Core Biopsy Needle (SharkCore) with a novel design has recently been introduced for endoscopic ultrasound guided Biopsy. There is as yet no data on how its diagnostic performance compares to the existing Core Biopsy Needle (ProCore) in the diagnosis of pancreatic masses. The aim of this study was to compare the diagnostic performance and yield of the two Core Biopsy Needles i.e. the ProCore and the SharkCore Needles in the Biopsy of solid pancreatic lesions. This is the first study in literature to compare 2 Core Biopsy Needles. Methods A retrospective comparison of a prospectively maintained database. Consecutive patients who had EUS guided fine Needle Biopsy with ProCore (100) and SharkCore (101) were included in the study. Demographic details, site of lesion, number of passes and histological diagnosis. Final diagnosis was based on positive histology or at least 6 months follow up in cases with a benign pathology. Primary outcome was to compare the diagnostic accuracy of the two Needles using only samples graded as definitely malignant as diagnostic for malignancy. The secondary outcome was to compare the diagnostic yield for both Needles. Results The sensitivity, specificity, negative predictive value and accuracy between the groups were - ProCore =71%, 100%, 28% and 74% vs. SharkCore =91%, 100%, 53% and 94%. There was a significant difference in sensitivity (p = 0.0003) and accuracy (p = 0.006). The proportion of samples classified as adequate for histological analysis was 87% for ProCore and 99% for SharkCore - this was significantly different (p = 0.0009). There were no complications in either group. Conclusion In this study the SharkCore Biopsy Needle demonstrated significantly better diagnostic accuracy and tissue yield. Prospective randomised studies are required. Disclosure of Interest None Declared
Kyu-bo Sung - One of the best experts on this subject based on the ideXlab platform.
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Transjugular Liver Biopsy in Patients with Liver Transplantation: Comparison of Quick-Core Biopsy and Forceps Biopsy.
Cardiovascular and interventional radiology, 2021Co-Authors: Gun Ha Kim, Dong-il Gwon, Kyu-bo SungAbstract:To compare the safety and efficacy of transjugular liver Biopsy (TJLB) using a Quick-Core Biopsy Needle or a forceps Biopsy in patients with liver transplantation (LT) who were suspected of having rejection. From June 2015 to January 2017, 98 TJLBs (60 patients) with the Quick-Core Biopsy Needle and 95 TJLBs (58 patients) with a forceps Biopsy system were attempted in patients with LT suspected of having rejection. Technical success, adequacy for diagnosis, number of Biopsy instrument passes, the maximum and mean length of the obtained samples, and the complications were retrospectively analyzed. TJLB was technically successful in all patients. Adequate specimens were obtained in 95.9% of the Biopsy Needle group and 91.6% in the forceps group (p = 0.246). The mean number of biopsies was 4.8 ± 1.8 in the Biopsy Needle group and 6.2 ± 1.7 in the forceps group. The mean size of the Biopsy sample was 11.1 ± 3.0 mm in the Biopsy Needle group and 2.5 ± 1.2 mm in the forceps group. Only one minor complication (a subcapsular hematoma) occurred in the Biopsy Needle group. No major complication was observed in any patient. TJLB using a Quick-Core Biopsy Needle or forceps can be safely and effectively performed in LT patients. The adequacy of sampling for diagnosis was equivalent between the groups. Level 4, case series.
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Transjugular Liver Biopsy in Patients with Liver Transplantation: Comparison of Quick-Core Biopsy and Forceps Biopsy
CardioVascular and Interventional Radiology, 2021Co-Authors: Gun Ha Kim, Dong-il Gwon, Kyu-bo SungAbstract:Purpose To compare the safety and efficacy of transjugular liver Biopsy (TJLB) using a Quick-Core Biopsy Needle or a forceps Biopsy in patients with liver transplantation (LT) who were suspected of having rejection. Materials and Methods From June 2015 to January 2017, 98 TJLBs (60 patients) with the Quick-Core Biopsy Needle and 95 TJLBs (58 patients) with a forceps Biopsy system were attempted in patients with LT suspected of having rejection. Technical success, adequacy for diagnosis, number of Biopsy instrument passes, the maximum and mean length of the obtained samples, and the complications were retrospectively analyzed. Results TJLB was technically successful in all patients. Adequate specimens were obtained in 95.9% of the Biopsy Needle group and 91.6% in the forceps group ( p = 0.246). The mean number of biopsies was 4.8 ± 1.8 in the Biopsy Needle group and 6.2 ± 1.7 in the forceps group. The mean size of the Biopsy sample was 11.1 ± 3.0 mm in the Biopsy Needle group and 2.5 ± 1.2 mm in the forceps group. Only one minor complication (a subcapsular hematoma) occurred in the Biopsy Needle group. No major complication was observed in any patient. Conclusion TJLB using a Quick-Core Biopsy Needle or forceps can be safely and effectively performed in LT patients. The adequacy of sampling for diagnosis was equivalent between the groups. Level of Evidence Level 4, case series
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Transfemoral liver Biopsy using a Quick-Core Biopsy Needle system in living donor liver transplantation recipients.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation S, 2014Co-Authors: Kyu-bo Sung, Dong-il Gwon, Jong Woo KimAbstract:The purpose of this study was to evaluate the efficacy and safety of transfemoral liver Biopsy with a Quick-Core Biopsy Needle in select living donor liver transplantation (LDLT) recipients. Eight LDLT recipients underwent 9 transfemoral liver Biopsy sessions. Six patients had undergone modified right lobe (mRL) LDLT, and 2 patients had undergone dual–left lobe LDLT. The indications for transfemoral liver Biopsy were a hepatic vein (HV) at an acute angle to the inferior vena cava (IVC) on the coronal plane and a thin (
Jin Hong Kim - One of the best experts on this subject based on the ideXlab platform.
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A prospective randomized trial of EUS-guided tissue acquisition using a 25-gauge Core Biopsy Needle with and without a stylet
Surgical Endoscopy, 2018Co-Authors: Min Jae Yang, Jae Chul Hwang, Byung Moo Yoo, Jin Hong Kim, Dakeun Lee, Hyunee Lim, Young Bae KimAbstract:Background Endoscopic ultrasound (EUS)-guided tissue acquisition has become the most effective method of obtaining specimens from a solid lesion adjacent to the gastrointestinal tract. No data exist regarding the use of a stylet in the Core Biopsy Needle during EUS-guided tissue acquisition. The aims of this study were to evaluate the feasibility, safety, and diagnostic yield of a 25-gauge Core Biopsy Needle without (S−) a stylet and to compare its performance with that of a 25-gauge Core Biopsy Needle with (S+) a stylet in patients with solid lesions adjacent to the gastrointestinal tract. Methods From November 2013 to January 2016, we performed 114 EUS-guided tissue acquisitions for the diagnosis of solid lesions adjacent to the gastrointestinal tract in a randomized controlled trial. Patients were randomly assigned to the S+ group ( n = 57) or the S− group ( n = 57). EUS-guided tissue acquisition was performed using a 25-gauge Core Biopsy Needle without an on-site cytopathologist. Results There were no significant differences in technical success (100 vs. 100%, p = 1.000), the mean number of Needle passes (7.0 ± 1.6 vs. 6.8 ± 1.5, p = 0.556), Needle malfunction (0 vs. 1.8%, p = 1.000), or complications (1.8 vs. 0%, p = 1.000) between the S+ and S− groups. Both groups exhibited comparable outcomes with respect to cytological diagnostic accuracy (93.0 vs. 91.2%, p = 1.000) and histological diagnostic accuracy (86.0 vs. 87.7%, p = 1.000) for malignancy. The procedure time was significantly shorter in the S− group than in the S+ group (32.4 ± 11.7 vs. 39.7 ± 8.6 min, p
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A prospective randomized trial of EUS-guided tissue acquisition using a 25-gauge Core Biopsy Needle with and without a stylet
Surgical endoscopy, 2018Co-Authors: Min Jae Yang, Jae Chul Hwang, Byung Moo Yoo, Jin Hong Kim, Dakeun Lee, Hyunee Lim, Young Bae KimAbstract:Background Endoscopic ultrasound (EUS)-guided tissue acquisition has become the most effective method of obtaining specimens from a solid lesion adjacent to the gastrointestinal tract. No data exist regarding the use of a stylet in the Core Biopsy Needle during EUS-guided tissue acquisition. The aims of this study were to evaluate the feasibility, safety, and diagnostic yield of a 25-gauge Core Biopsy Needle without (S−) a stylet and to compare its performance with that of a 25-gauge Core Biopsy Needle with (S+) a stylet in patients with solid lesions adjacent to the gastrointestinal tract.