The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform
Laurent Legendre - One of the best experts on this subject based on the ideXlab platform.
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secondary metabolite diversity in taro colocasia esculenta l schott Corms
Journal of Food Composition and Analysis, 2016Co-Authors: Roger Malapa, Serge Michalet, Vincent Lebot, Laurent Legendre, Ismael MunozcuervoAbstract:Abstract Taro, Colocasia esculenta (L.) Schott, is one of the oldest major staple food crops of tropical regions. This study represents one the first in-depth surveys of taro biodiversity based on Corms flesh secondary metabolites fingerprints. Out of the 167 analyzed cultivars, 70 UV-absorbing substances were annotated according to their retention time, UV/vis absorption spectrum, high resolution mass (by HRMS) and fragmentation pattern (tandem MS-MS). They included 6 carotenoids, 35 flavones/flavonols, 6 flavanones, 2 flavanols and 1 indol. Twenty flavones that were glycosylated forms of apigenin, luteolin and chrysoeriol conferred to the Corms a yellow color and defined a low abundance (ca. 10% of cultivars) chemotype. Their accumulation negatively correlated with flavanones which were annotated for the first time in taro. Orange flesh Corms were characterized by high levels of β-carotene. Secondary metabolite-based chemotypes displayed no geographical distribution pattern.
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Secondary metabolite diversity in taro, Colocasia esculenta (L.) Schott, Corms
Journal of Food Composition and Analysis, 2016Co-Authors: Ismaël Munoz, Roger Malapa, Serge Michalet, Vincent Lebot, Laurent LegendreAbstract:Taro, Colocasia esculenta (L.) Schott, is one of the oldest major staple food crops of tropical regions. This study represents one the first in-depth surveys of taro biodiversity based on Corms flesh secondary metabolites fingerprints. Out of the 167 analyzed cultivars, 70 UV-absorbing substances were annotated according to their retention time, UV/vis absorption spectrum, high resolution mass (by HRMS) and fragmentation pattern (tandem MS-MS). They included 6 carotenoids, 35 flavones/flavonols, 6 flavanones, 2 flavanols and 1 indol. Twenty flavones that were glycosylated forms of apigenin, luteolin and chrysoeriol conferred to the Corms a yellow color and defined a low abundance (ca. 10% of cultivars) chemotype. Their accumulation negatively correlated with flavanones which were annotated for the first time in taro. Orange flesh Corms were characterized-by high levels of beta-carotene. Secondary metabolite based chemotypes displayed no geographical distribution pattern.
Ian J. S. Fairlamb - One of the best experts on this subject based on the ideXlab platform.
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Redox-Tagged Carbon Monoxide-Releasing Molecules (Corms): Ferrocene-Containing [Mn(C^N)(CO)4] Complexes as a Promising New CORM Class.
Inorganic chemistry, 2017Co-Authors: Benjamin J. Aucott, Jonathan S. Ward, Samuel Andrew, Jessica Milani, Adrian C. Whitwood, Jason M. Lynam, Alison Parkin, Ian J. S. FairlambAbstract:This study describes the synthesis and characterization of a new class of ferrocene-containing carbon monoxide-releasing molecules (Corms, 1-3). The ferrocenyl group is both a recognized therapeutically viable coligand and a handle for informative infrared spectroelectrochemistry. Deoxymyoglobin CO-release assays and in situ infrared spectroscopy confirm compounds 2 and 3 as photoCorms and 1 as a thermal CORM, attributed to the increased sensitivity of the Mn-ferrocenyl bond to protonation in 1. Electrochemical and infrared spectroelectrochemical experiments confirm a single reversible redox couple associated with the ferrocenyl moiety with the Mn tetracarbonyl center showing no redox activity up to +590 mV vs Fc/Fc+, though no concomitant CO release was observed in association with the redox activity. The effects of linker length on communication between the Fe and Mn centers suggest that the incorporation of redox-active ligands into Corms focuses on the first coordination sphere of the CORM. Redox-tagged Corms could prove to be a useful mechanistic probe; our findings could be developed to use redox changes to trigger CO release.
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redox tagged carbon monoxide releasing molecules Corms ferrocene containing mn c n co 4 complexes as a promising new corm class
Inorganic Chemistry, 2017Co-Authors: Benjamin J. Aucott, Jonathan S. Ward, Samuel Andrew, Jessica Milani, Adrian C. Whitwood, Jason M. Lynam, Alison Parkin, Ian J. S. FairlambAbstract:This study describes the synthesis and characterization of a new class of ferrocene-containing carbon monoxide-releasing molecules (Corms, 1–3). The ferrocenyl group is both a recognized therapeutically viable coligand and a handle for informative infrared spectroelectrochemistry. Deoxymyoglobin CO-release assays and in situ infrared spectroscopy confirm compounds 2 and 3 as photoCorms and 1 as a thermal CORM, attributed to the increased sensitivity of the Mn–ferrocenyl bond to protonation in 1. Electrochemical and infrared spectroelectrochemical experiments confirm a single reversible redox couple associated with the ferrocenyl moiety with the Mn tetracarbonyl center showing no redox activity up to +590 mV vs Fc/Fc+, though no concomitant CO release was observed in association with the redox activity. The effects of linker length on communication between the Fe and Mn centers suggest that the incorporation of redox-active ligands into Corms focuses on the first coordination sphere of the CORM. Redox-tagg...
Benjamin J. Aucott - One of the best experts on this subject based on the ideXlab platform.
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Redox-Tagged Carbon Monoxide-Releasing Molecules (Corms): Ferrocene-Containing [Mn(C^N)(CO)4] Complexes as a Promising New CORM Class.
Inorganic chemistry, 2017Co-Authors: Benjamin J. Aucott, Jonathan S. Ward, Samuel Andrew, Jessica Milani, Adrian C. Whitwood, Jason M. Lynam, Alison Parkin, Ian J. S. FairlambAbstract:This study describes the synthesis and characterization of a new class of ferrocene-containing carbon monoxide-releasing molecules (Corms, 1-3). The ferrocenyl group is both a recognized therapeutically viable coligand and a handle for informative infrared spectroelectrochemistry. Deoxymyoglobin CO-release assays and in situ infrared spectroscopy confirm compounds 2 and 3 as photoCorms and 1 as a thermal CORM, attributed to the increased sensitivity of the Mn-ferrocenyl bond to protonation in 1. Electrochemical and infrared spectroelectrochemical experiments confirm a single reversible redox couple associated with the ferrocenyl moiety with the Mn tetracarbonyl center showing no redox activity up to +590 mV vs Fc/Fc+, though no concomitant CO release was observed in association with the redox activity. The effects of linker length on communication between the Fe and Mn centers suggest that the incorporation of redox-active ligands into Corms focuses on the first coordination sphere of the CORM. Redox-tagged Corms could prove to be a useful mechanistic probe; our findings could be developed to use redox changes to trigger CO release.
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redox tagged carbon monoxide releasing molecules Corms ferrocene containing mn c n co 4 complexes as a promising new corm class
Inorganic Chemistry, 2017Co-Authors: Benjamin J. Aucott, Jonathan S. Ward, Samuel Andrew, Jessica Milani, Adrian C. Whitwood, Jason M. Lynam, Alison Parkin, Ian J. S. FairlambAbstract:This study describes the synthesis and characterization of a new class of ferrocene-containing carbon monoxide-releasing molecules (Corms, 1–3). The ferrocenyl group is both a recognized therapeutically viable coligand and a handle for informative infrared spectroelectrochemistry. Deoxymyoglobin CO-release assays and in situ infrared spectroscopy confirm compounds 2 and 3 as photoCorms and 1 as a thermal CORM, attributed to the increased sensitivity of the Mn–ferrocenyl bond to protonation in 1. Electrochemical and infrared spectroelectrochemical experiments confirm a single reversible redox couple associated with the ferrocenyl moiety with the Mn tetracarbonyl center showing no redox activity up to +590 mV vs Fc/Fc+, though no concomitant CO release was observed in association with the redox activity. The effects of linker length on communication between the Fe and Mn centers suggest that the incorporation of redox-active ligands into Corms focuses on the first coordination sphere of the CORM. Redox-tagg...
Serge Michalet - One of the best experts on this subject based on the ideXlab platform.
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secondary metabolite diversity in taro colocasia esculenta l schott Corms
Journal of Food Composition and Analysis, 2016Co-Authors: Roger Malapa, Serge Michalet, Vincent Lebot, Laurent Legendre, Ismael MunozcuervoAbstract:Abstract Taro, Colocasia esculenta (L.) Schott, is one of the oldest major staple food crops of tropical regions. This study represents one the first in-depth surveys of taro biodiversity based on Corms flesh secondary metabolites fingerprints. Out of the 167 analyzed cultivars, 70 UV-absorbing substances were annotated according to their retention time, UV/vis absorption spectrum, high resolution mass (by HRMS) and fragmentation pattern (tandem MS-MS). They included 6 carotenoids, 35 flavones/flavonols, 6 flavanones, 2 flavanols and 1 indol. Twenty flavones that were glycosylated forms of apigenin, luteolin and chrysoeriol conferred to the Corms a yellow color and defined a low abundance (ca. 10% of cultivars) chemotype. Their accumulation negatively correlated with flavanones which were annotated for the first time in taro. Orange flesh Corms were characterized by high levels of β-carotene. Secondary metabolite-based chemotypes displayed no geographical distribution pattern.
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Secondary metabolite diversity in taro, Colocasia esculenta (L.) Schott, Corms
Journal of Food Composition and Analysis, 2016Co-Authors: Ismaël Munoz, Roger Malapa, Serge Michalet, Vincent Lebot, Laurent LegendreAbstract:Taro, Colocasia esculenta (L.) Schott, is one of the oldest major staple food crops of tropical regions. This study represents one the first in-depth surveys of taro biodiversity based on Corms flesh secondary metabolites fingerprints. Out of the 167 analyzed cultivars, 70 UV-absorbing substances were annotated according to their retention time, UV/vis absorption spectrum, high resolution mass (by HRMS) and fragmentation pattern (tandem MS-MS). They included 6 carotenoids, 35 flavones/flavonols, 6 flavanones, 2 flavanols and 1 indol. Twenty flavones that were glycosylated forms of apigenin, luteolin and chrysoeriol conferred to the Corms a yellow color and defined a low abundance (ca. 10% of cultivars) chemotype. Their accumulation negatively correlated with flavanones which were annotated for the first time in taro. Orange flesh Corms were characterized-by high levels of beta-carotene. Secondary metabolite based chemotypes displayed no geographical distribution pattern.
Ismael Munozcuervo - One of the best experts on this subject based on the ideXlab platform.
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secondary metabolite diversity in taro colocasia esculenta l schott Corms
Journal of Food Composition and Analysis, 2016Co-Authors: Roger Malapa, Serge Michalet, Vincent Lebot, Laurent Legendre, Ismael MunozcuervoAbstract:Abstract Taro, Colocasia esculenta (L.) Schott, is one of the oldest major staple food crops of tropical regions. This study represents one the first in-depth surveys of taro biodiversity based on Corms flesh secondary metabolites fingerprints. Out of the 167 analyzed cultivars, 70 UV-absorbing substances were annotated according to their retention time, UV/vis absorption spectrum, high resolution mass (by HRMS) and fragmentation pattern (tandem MS-MS). They included 6 carotenoids, 35 flavones/flavonols, 6 flavanones, 2 flavanols and 1 indol. Twenty flavones that were glycosylated forms of apigenin, luteolin and chrysoeriol conferred to the Corms a yellow color and defined a low abundance (ca. 10% of cultivars) chemotype. Their accumulation negatively correlated with flavanones which were annotated for the first time in taro. Orange flesh Corms were characterized by high levels of β-carotene. Secondary metabolite-based chemotypes displayed no geographical distribution pattern.