The Experts below are selected from a list of 18 Experts worldwide ranked by ideXlab platform
Norberto Cysne Coimbra - One of the best experts on this subject based on the ideXlab platform.
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topographic and functional neuroanatomical study of gabaergic disinhibitory striatum nigral inputs and inhibitory nigrocollicular pathways neural hodology recruiting the substantia nigra pars reticulata for the modulation of the neural activity in th
Journal of Chemical Neuroanatomy, 2006Co-Authors: Lissandra Castellanbaldan, Mateus Da Costa Kawasaki, Sandro Jose Ribeiro, Fabricio Calvo, Vani Maria Alves Correa, Norberto Cysne CoimbraAbstract:Considering the influence of the substantia nigra on mesencephalic neurons involved with fear-induced reactions organized in rostral aspects of the dorsal midbrain, the present work investigated the topographical and functional neuroanatomy of similar influence on caudal division of the Corpora quadrigemina, addressing: (a) the neural hodology connecting the neostriatum, the substantia nigra, periaqueductal gray matter and inferior colliculus (IC) neural networks; (b) the influence of the inhibitory neostriatonigral-nigrocollicular GABAergic links on the control of the defensive behavior organized in the IC. The effects of the increase or decrease of activity of nigrocollicular inputs on defensive responses elicited by either electrical or chemical stimulation of the IC were also determined. Electrolytic or chemical lesions of the substantia nigra, pars reticulata (SNpr), decreased the freezing and escape behaviors thresholds elicited by electrical stimulation of the IC, and increased the behavioral responses evoked by the GABAA blockade in the same sites of the mesencephalic tectum (MT) electrically stimulated. These findings were corroborated by similar effects caused by microinjections of the GABAA-receptor agonist muscimol in the SNpr, followed by electrical and chemical stimulations of the IC. The GABAA blockade in the SNpr caused a significant increase in the defensive behavior thresholds elicited by electrical stimulation of the IC and a decrease in the mean incidence of panic-like responses induced by microinjections of bicuculline in the mesencephalic tectum (inferior colliculus). These findings suggest that the substantia nigra receives GABAergic inputs that modulate local and also inhibitory GABAergic outputs toward the IC. In fact, neurotracing experiments with fast blue and iontophoretic microinjections of biotinylated dextran amine either into the inferior colliculus or in the reticular division of the substantia nigra demonstrated a neural link between these structures, as well as between the neostriatum and SNpr.
D G Dzhavadov - One of the best experts on this subject based on the ideXlab platform.
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the effect of the impulse stimulation of the posterior hypothalamus on the function of the superior colliculi of the Corpora quadrigemina
Fiziologicheskiĭ zhurnal, 1991Co-Authors: N A Gadzhieva, D G DzhavadovAbstract:Single stimuli applied to the posterior hypothalamus of alert rabbits induced short-latency responses in the superior colliculus. The data obtained suggests existence of phasic mechanisms in hypothalamic control of the superior colliculus' function.
Lissandra Castellanbaldan - One of the best experts on this subject based on the ideXlab platform.
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topographic and functional neuroanatomical study of gabaergic disinhibitory striatum nigral inputs and inhibitory nigrocollicular pathways neural hodology recruiting the substantia nigra pars reticulata for the modulation of the neural activity in th
Journal of Chemical Neuroanatomy, 2006Co-Authors: Lissandra Castellanbaldan, Mateus Da Costa Kawasaki, Sandro Jose Ribeiro, Fabricio Calvo, Vani Maria Alves Correa, Norberto Cysne CoimbraAbstract:Considering the influence of the substantia nigra on mesencephalic neurons involved with fear-induced reactions organized in rostral aspects of the dorsal midbrain, the present work investigated the topographical and functional neuroanatomy of similar influence on caudal division of the Corpora quadrigemina, addressing: (a) the neural hodology connecting the neostriatum, the substantia nigra, periaqueductal gray matter and inferior colliculus (IC) neural networks; (b) the influence of the inhibitory neostriatonigral-nigrocollicular GABAergic links on the control of the defensive behavior organized in the IC. The effects of the increase or decrease of activity of nigrocollicular inputs on defensive responses elicited by either electrical or chemical stimulation of the IC were also determined. Electrolytic or chemical lesions of the substantia nigra, pars reticulata (SNpr), decreased the freezing and escape behaviors thresholds elicited by electrical stimulation of the IC, and increased the behavioral responses evoked by the GABAA blockade in the same sites of the mesencephalic tectum (MT) electrically stimulated. These findings were corroborated by similar effects caused by microinjections of the GABAA-receptor agonist muscimol in the SNpr, followed by electrical and chemical stimulations of the IC. The GABAA blockade in the SNpr caused a significant increase in the defensive behavior thresholds elicited by electrical stimulation of the IC and a decrease in the mean incidence of panic-like responses induced by microinjections of bicuculline in the mesencephalic tectum (inferior colliculus). These findings suggest that the substantia nigra receives GABAergic inputs that modulate local and also inhibitory GABAergic outputs toward the IC. In fact, neurotracing experiments with fast blue and iontophoretic microinjections of biotinylated dextran amine either into the inferior colliculus or in the reticular division of the substantia nigra demonstrated a neural link between these structures, as well as between the neostriatum and SNpr.
L I Changyua - One of the best experts on this subject based on the ideXlab platform.
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microsurgical anatomy of transoccipito supratentorial approach of key hole to the pineal region
Clinical neurosurgery, 2006Co-Authors: L I ChangyuaAbstract:Objective To study the microsurgical anatomy of the transoccipito-supratentorial approach of key hole to the pineal region. Methods Ten cadaveric heads fixed with formalin, in which the arteries and veins were perfused by red or blue color latex, were dissected with microsurgical anatomical skills to observe the ambien cisternat, quadrigeminal cistern, corpus callosum, the pos-terior of the third ventricle, system of Galen veins, pineal gland and Corpora quadrigemina. Results The exposure extent of the pineal region via the transoccipito-supratentorial key hole approach was similar to that via the routine transoccipito-supratentorial approach, but the useless exposure of the brain and the injury of the tissue due to brain traction are less through the former than that through the latter. Conclusion The surgery for the lesions in the pineal region is feasible via the transoccipito-supratentorial key hole operation approach.
N Ashok - One of the best experts on this subject based on the ideXlab platform.
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histogenesis of Corpora quadrigemina in goat foetuses
Indian Journal of Animal Research, 2008Co-Authors: K M Lucy, K R Harshan, J J Chungath, N AshokAbstract:Prenatal development of the Corpora quadrigemina in the brain of goats was studied using 52 foetuses ranging from a crown rump length (CRL) of 1.4 cm (24 days of gestation) to 41.5 cm (full term). During the seventh week, the primordial quadrigeminal plate appeared in the alar plate region of mesencephalon. The neuroblasts from the inner ependymal layer invaded the dorsal marginal zone of the tectum to form the rostral and caudal colliculi. By 76 days of gestation, the tectum revealed numerous nuclear masses. Neurons and glial cells of the tectum were differentiated towards term. Rostral colliculi showed a laminated structure consisting of stratum zonale, stratum cinerium, stratum opticum and stratum lemnisci from outer to inner. Caudal colliculi were homogeneous without any lamination.
